Wastewater monitoring of human and avian influenza A viruses in Northern Ireland: a genomic surveillance study

Authors: Lee, Andrew J, Carson, Stephen, Reyne, Marina I, Marshall, Andrew, Moody, Daniel, Allen, Danielle M, Allingham, Pearce, Levickas, Ashley, Fitzgerald, Arthur, Bell, Stephen H, Lock, Jonathan, Coey, Jonathon D, McSparron, Cormac, Nejad, Behnam F, Troendle, Evan P, Simpson, David A, Courtney, David G, Einarsson, Gisli G, McKenna, James P, Fairley, Derek J, Curran, Tanya, McKinley, Jennifer M, Gilpin, Deirdre F, Lemon, Ken, McGrath, John W, Bamford, Connor G G

Source: In The Lancet Microbe December 2024 5(12)

SARS-CoV-2 introductions to the island of Ireland: a phylogenetic and geospatiotemporal study of infection dynamics.

Authors: Rice, Alan M., Troendle, Evan P., Bridgett, Stephen J., Firoozi Nejad, Behnam, McKinley, Jennifer M., Bradley, Declan T., Fairley, Derek J., Bamford, Connor G. G., Skvortsov, Timofey, Simpson, David A.

Source: Genome Medicine; 12/19/2024, Vol. 16 Issue 1, p1-27, 27p

Subject Terms: PUBLIC health surveillance, SARS-CoV-2 Omicron variant, WHOLE genome sequencing, COVID-19 pandemic, COUNTRY of origin (Immigrants), PARSIMONIOUS models

Direct Antiviral Activity of IFN-Stimulated Genes Is Responsible for Resistance to Paramyxoviruses in ISG15-Deficient Cells

Authors: Holthaus, David, Vasou, Andri, Bamford, Connor G. G., Andrejeva, Jelena, Paulus, Christina, Randall, Richard E., McLauchlan, John, Hughes, David J.

Source: Journal of immunology. 205(1):261-271

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624156054&indx=1&recIds=ETOCRN624156054

A Human and Rhesus Macaque Interferon-Stimulated Gene Screen Shows That Over-Expression of ARHGEF3/XPLN Inhibits Replication of Hepatitis C Virus and Other Flavivirids.

Authors: Bamford, Connor G. G.^1,2 (AUTHOR) c.bamford@qub.ac.uk, Aranday-Cortes, Elihu¹ (AUTHOR) elihu.aranday-cortes@glasgow.ac.uk, Sanchez-Velazquez, Ricardo^1,3 (AUTHOR) ricardo.sanchez@biontech.de, Mullan, Catrina¹ (AUTHOR) c.mullan.1@research.gla.ac.uk, Kohl, Alain¹ (AUTHOR) alain.kohl@glasgow.ac.uk, Patel, Arvind H.¹ (AUTHOR) arvind.patel@glasgow.ac.uk, Wilson, Sam J.¹ (AUTHOR) sam.wilson@glasgow.ac.uk, McLauchlan, John¹ (AUTHOR) john.mclauchlan@glasgow.ac.uk

Source: Viruses (1999-4915). Aug2022, Vol. 14 Issue 8, p1655-1655. 18p.

Subject Terms: *MACAQUES, *RHESUS monkeys, *GUANINE nucleotide exchange factors, *HEPATITIS C virus, *SIMIAN immunodeficiency virus, *YELLOW fever, *ZIKA virus

Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV‐2 spike

Authors: Cantoni, Diego, Murray, Matthew J, Kalemera, Mphatso D, Dicken, Samuel J, Stejskal, Lenka, Brown, Georgina, Lytras, Spyros, Coey, Jonathon D, McKenna, James, Bridgett, Stephen, Simpson, David, Fairley, Derek, Thorne, Lucy G, Reuschl, Ann‐Kathrin, Forrest, Calum, Ganeshalingham, Maaroothen, Muir, Luke, Palor, Machaela, Jarvis, Lisa, Willett, Brian, Power, Ultan F, McCoy, Laura E, Jolly, Clare, Towers, Greg J, Doores, Katie J, Robertson, David L, Shepherd, Adrian J, Reeves, Matthew B, Bamford, Connor G G, Grove, Joe

Source: EMBO reports. 23(10)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181986263.0x000001&indx=1&recIds=ETOCvdc_100181986263.0x000001

Comparative analysis of genome-encoded viral sequences reveals the evolutionary history of flavivirids (family Flaviviridae)

Authors: Bamford, Connor G G, de Souza, William M, Parry, Rhys, Gifford, Robert J

Source: Virus evolution. 8(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165486066.0x000001&indx=1&recIds=ETOCvdc_100165486066.0x000001

The evolutionary dynamics and epidemiological history of hepatitis C virus genotype 6, including unique strains from the Li community of Hainan Island, China

Authors: Xu, Ru, Aranday-Cortes, Elihu, Leitch, E Carol McWilliam, Hughes, Joseph, Singer, Joshua B, Sreenu, Vattipally, Tong, Lily, da Silva Filipe, Ana, Bamford, Connor G G, Rong, Xia, Huang, Jieting, Wang, Min, Fu, Yongshui, McLauchlan, John

Source: Virus evolution. 8(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163858362.0x000001&indx=1&recIds=ETOCvdc_100163858362.0x000001

An endogenously activated antiviral state restricts SARS-CoV-2 infection in differentiated primary airway epithelial cells.

Authors: Broadbent, Lindsay¹ (AUTHOR) l.broadbent@qub.ac.uk, Bamford, Connor G. G.¹ (AUTHOR), Lopez Campos, Guillermo¹ (AUTHOR), Manzoor, Sheerien¹ (AUTHOR), Courtney, David¹ (AUTHOR), Ali, Ahlam^1,2 (AUTHOR), Touzelet, Olivier¹ (AUTHOR), McCaughey, Conall³ (AUTHOR), Mills, Ken² (AUTHOR), Power, Ultan F.¹ (AUTHOR) l.broadbent@qub.ac.uk

Source: PLoS ONE. 4/18/2022, Vol. 17 Issue 4, p1-14. 14p.

Subject Terms: *COVID-19, *SARS-CoV-2, *EPITHELIAL cells, *RESPIRATORY syncytial virus

Type 1 interferon auto-antibodies are elevated in patients with decompensated liver cirrhosis.

Authors: Greville, Gordon, Cremen, Sinead, O'Neill, Shauna, Azarian, Sarah, Brady, Gareth, McCormack, William, Dyer, Adam H, Bourke, Nollaig M, Touzelet, Olivier, Courtney, David, Power, Ultan F, Dowling, Paul, Gallagher, Tom K, Bamford, Connor G G, Robinson, Mark W

Source: Clinical & Experimental Immunology; Feb2024, Vol. 215 Issue 2, p177-189, 13p

Subject Terms: TYPE I interferons, CIRRHOSIS of the liver, AUTOANTIBODIES, SARS-CoV-2, VIRUS diseases

Two courses of deconstructed coronavirus please.

Authors: Bamford, Connor G. G.¹ (AUTHOR) c.bamford@qub.ac.uk

Source: PLoS Pathogens. 4/29/2021, Vol. 17 Issue 4, p1-4. 4p.

Subject Terms: *COVID-19, *MERS coronavirus, *PANDEMICS

Improved recovery of SARS-CoV-2 from wastewater through application of RNA and DNA stabilising agents.

Authors: Bell, Stephen H, Allen, Danielle M, Reyne, Marina I, Lock, Jonathan F W, Fitzgerald, Arthur, Levickas, Ashley, Lee, Andrew J, Bamford, Connor G G, Gilpin, Deirdre F, McGrath, John W

Source: Letters in Applied Microbiology; Jun2023, Vol. 76 Issue 6, p1-6, 6p

Subject Terms: SEWAGE, SARS-CoV-2, RNA, RIBONUCLEASES, COMMUNITIES

The antiviral state has shaped the CpG composition of the vertebrate interferome to avoid self-targeting.

Authors: Shaw, Andrew E.^1,2, Rihn, Suzannah J.¹, Mollentze, Nardus^1,3, Wickenhagen, Arthur¹, Stewart, Douglas G.¹, Orton, Richard J.¹, Kuchi, Srikeerthana¹, Bakshi, Siddharth¹, Collados, Mila Rodriguez¹, Turnbull, Matthew L.¹, Busby, Joseph¹, Gu, Quan¹, Smollett, Katherine¹, Bamford, Connor G. G.¹, Sugrue, Elena¹, Johnson, Paul C. D.^1,3, Da Silva, Ana Filipe¹, Castello, Alfredo¹, Streicker, Daniel G.^1,3, Robertson, David L.¹

Source: PLoS Biology; 9/7/2021, Vol. 19 Issue 9, p1-25, 25p, 5 Graphs

A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages.

Authors: Bamford, Connor G. G.¹, Aranday-Cortes, Elihu¹, Filipe, Ines Cordeiro¹, Sukumar, Swathi¹, Mair, Daniel¹, Filipe, Ana da Silva¹, Mendoza, Juan L.², Garcia, K. Christopher², Fan, Shaohua³, Tishkoff, Sarah A.³, McLauchlan, John¹ john.mclauchlan@glasgow.ac.uk

Source: PLoS Pathogens. 10/11/2018, Vol. 14 Issue 10, p1-35. 35p.

Subject Terms: *INTERFERONS, *OXIDOREDUCTASES, *HEPATITIS C virus, *ANTIRETROVIRAL agents, *ENZYMOLOGY, *CHIMPANZEES

evolutionary dynamics and epidemiological history of hepatitis C virus genotype 6, including unique strains from the Li community of Hainan Island, China.

Authors: Xu, Ru, Aranday-Cortes, Elihu, Leitch, E Carol McWilliam, Hughes, Joseph, Singer, Joshua B, Sreenu, Vattipally, Tong, Lily, Filipe, Ana da Silva, Bamford, Connor G G, Rong, Xia, Huang, Jieting, Wang, Min, Fu, Yongshui, McLauchlan, John

Source: Virus Evolution; 2022, Vol. 8 Issue 1, p1-11, 11p

Subject Terms: HEPATITIS C virus, WHOLE genome sequencing, GENOTYPES, MOLECULAR evolution, ETHNIC groups

Geographic Terms: HAINAN Sheng (China), CHINA

Conserved Induction of Distinct Antiviral Signalling Kinetics by Primate Interferon Lambda 4 Proteins.

Authors: Guo, Cuncai, Reuss, Dorothee, Coey, Jonathon D., Sukumar, Swathi, Lang, Benjamin, McLauchlan, John, Boulant, Steeve, Stanifer, Megan L., Bamford, Connor G. G.

Source: Frontiers in Immunology; 11/18/2021, Vol. 12, p1-14, 14p

Subject Terms: INTERFERONS, PRIMATES, HEPATITIS C virus, GASTROINTESTINAL system, CYTOKINES

Comparison of SARS-CoV-2 Evolution in Paediatric Primary Airway Epithelial Cell Cultures Compared with Vero-Derived Cell Lines.

Authors: Bamford, Connor G. G.¹ (AUTHOR) L.Broadbent@qub.ac.uk, Broadbent, Lindsay¹ (AUTHOR) mmccabe783@qub.ac.uk, Aranday-Cortes, Elihu² (AUTHOR) elihu.aranday-cortes@glasgow.ac.uk, McCabe, Mary¹ (AUTHOR) david.courtney@qub.ac.uk, McKenna, James³ (AUTHOR) james.mckenna@belfasttrust.hscni.net, Courtney, David G.¹ (AUTHOR) o.touzelet@qub.ac.uk, Touzelet, Olivier¹ (AUTHOR) a.ali@qub.ac.uk, Ali, Ahlam^1,4 (AUTHOR) g.roberts@qub.ac.uk, Roberts, Grace¹ (AUTHOR) G.LopezCampos@qub.ac.uk, Lopez Campos, Guillermo¹ (AUTHOR) david.simpson@qub.ac.uk, Simpson, David¹ (AUTHOR), McCaughey, Conall³ (AUTHOR) conall.mccaughey@belfasttrust.hscni.net, Fairley, Derek³ (AUTHOR) derek.fairley@belfasttrust.hscni.net, Mills, Ken⁴ (AUTHOR), Power, Ultan F.¹ (AUTHOR) c.bamford@qub.ac.uk

Source: Viruses (1999-4915). Feb2022, Vol. 14 Issue 2, p325. 1p.

Subject Terms: *EPITHELIAL cell culture, *SARS-CoV-2, *CELL lines, *PHENOTYPIC plasticity, *PEDIATRICS

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mSphere of Influence: Interferon Ultra Is a Means To Fight Viral Disease.

Authors: Bamford, Connor G. G.

Source: MSphere; Mar/Apr2020, Vol. 5 Issue 2, p1-3, 3p

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