Cumulative suppressive index as a predictor of relapse free survival and overall survival in Human Papilloma Virus‐negative oral squamous cell carcinomas with negative resection margins

Authors: Hum, Lauren, Bethmann, Daniel, Feng, Zipei, Chang, Shu‐Ching, Eckert, Alexander, Ballesteros‐Merino, Carmen, Keschke, Claudia, Kappler, Matthias, Bifulco, Carlo B., Wickenhauser, Claudia, Seliger, Barbara, Fox, Bernard A., Bell, Richard

Source: Head & neck. 43(2):568-576

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112575658.0x000001&indx=1&recIds=ETOCvdc_100112575658.0x000001

Future Research Goals in Immunotherapy

Authors: Hulett, Tyler W., Fox, Bernard A., Messenheimer, David J., Marwitz, Sebastian, Moudgil, Tarsem, Afentoulis, Michael E., Wegman, Keith W., Ballesteros-Merino, Carmen, Jensen, Shawn M.

Source: In Surgical Oncology Clinics of North America July 2019 28(3):505-518

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

Authors: Pagès, Franck, Mlecnik, Bernhard, Marliot, Florence, Bindea, Gabriela, Ou, Fang-Shu, Bifulco, Carlo, Lugli, Alessandro, Zlobec, Inti, Rau, Tilman T, Berger, Martin D, Nagtegaal, Iris D, Vink-Börger, Elisa, Hartmann, Arndt, Geppert, Carol, Kolwelter, Julie, Merkel, Susanne, Grützmann, Robert, Van den Eynde, Marc, Jouret-Mourin, Anne, Kartheuser, Alex, Léonard, Daniel, Remue, Christophe, Wang, Julia Y, Bavi, Prashant, Roehrl, Michael H A, Ohashi, Pamela S, Nguyen, Linh T, Han, SeongJun, MacGregor, Heather L, Hafezi-Bakhtiari, Sara, Wouters, Bradly G, Masucci, Giuseppe V, Andersson, Emilia K, Zavadova, Eva, Vocka, Michal, Spacek, Jan, Petruzelka, Lubos, Konopasek, Bohuslav, Dundr, Pavel, Skalova, Helena, Nemejcova, Kristyna, Botti, Gerardo, Tatangelo, Fabiana, Delrio, Paolo, Ciliberto, Gennaro, Maio, Michele, Laghi, Luigi, Grizzi, Fabio, Fredriksen, Tessa, Buttard, Bénédicte, Angelova, Mihaela, Vasaturo, Angela, Maby, Pauline, Church, Sarah E, Angell, Helen K, Lafontaine, Lucie, Bruni, Daniela, El Sissy, Carine, Haicheur, Nacilla, Kirilovsky, Amos, Berger, Anne, Lagorce, Christine, Meyers, Jeffrey P, Paustian, Christopher, Feng, Zipei, Ballesteros-Merino, Carmen, Dijkstra, Jeroen, van de Water, Carlijn, van Lent-van Vliet, Shannon, Knijn, Nikki, Mușină, Ana-Maria, Scripcariu, Dragos-Viorel, Popivanova, Boryana, Xu, Mingli, Fujita, Tomonobu, Hazama, Shoichi, Suzuki, Nobuaki, Nagano, Hiroaki, Okuno, Kiyotaka, Torigoe, Toshihiko, Sato, Noriyuki, Furuhata, Tomohisa, Takemasa, Ichiro, Itoh, Kyogo, Patel, Prabhu S, Vora, Hemangini H, Shah, Birva, Patel, Jayendrakumar B, Rajvik, Kruti N, Pandya, Shashank J, Shukla, Shilin N, Wang, Yili, Zhang, Guanjun, Kawakami, Yutaka, Marincola, Francesco M, Ascierto, Paolo A, Sargent, Daniel J, Fox, Bernard A, Galon, Jérôme

Source: In The Lancet 26 May-1 June 2018 391(10135):2128-2139

Impact of moderate prenatal alcohol exposure on histaminergic neurons, histidine decarboxylase levels and histamine H2 receptors in adult rat offspring

Authors: Davies, Suzy, Ballesteros-Merino, Carmen, Allen, Nyika A., Porch, Morgan W., Pruitt, Morgan E., Christensen, Kyle H., Rosenberg, Martina J., Savage, Daniel D.

Source: Alcohol. 76:47-57

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100082084181.0x000001&indx=1&recIds=ETOCvdc_100082084181.0x000001

Multispectral Fluorescence Imaging Allows for Distinctive Topographic Assessment and Subclassification of Tumor-Infiltrating and Surrounding Immune Cells

Authors: Wickenhauser, Claudia, Bethmann, Daniel, Feng, Zipei, Jensen, Shawn M., Ballesteros-Merino, Carmen, Massa, Chiara, Steven, Andre, Bauer, Marcus, Kaatzsch, Peter, Pazaitis, Nikolaos

Source: Methods in molecular biology. 1913:13-32

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN619265724&indx=1&recIds=ETOCRN619265724

Novel frontiers in detecting cancer metastasis

Authors: Leong, Stanley P., Ballesteros-Merino, Carmen, Jensen, Shawn M., Marwitz, Sebastian, Bifulco, Carlo, Fox, Bernard A., Skoberne, Mojca

Source: Clinical and experimental metastasis. 35(5-6):403-412

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127161797.0x000001&indx=1&recIds=ETOCvdc_100127161797.0x000001

Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination

Authors: Hulett, Tyler, Jensen, Shawn, Wilmarth, Phillip, Reddy, Ashok, Ballesteros-Merino, Carmen, Afentoulis, Michael, Dubay, Christopher, David, Larry, Fox, Bernard

Source: Journal for immunotherapy of cancer. 6(1):1-14

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165364477.0x000001&indx=1&recIds=ETOCvdc_100165364477.0x000001

A Network Landscape of HPVOPC Reveals Methylation Alterations as Significant Drivers of Gene Expression via an Immune-Mediated GPCR Signal.

Authors: Qualliotine, Jesse R., Nakagawa, Takuya, Rosenthal, Sara Brin, Sadat, Sayed, Ballesteros-Merino, Carmen, Xu, Guorong, Mark, Adam, Nasamran, Art, Gutkind, J. Silvio, Fisch, Kathleen M., Guo, Theresa, Fox, Bernard A., Khan, Zubair, Molinolo, Alfredo A., Califano, Joseph A.

Source: Cancers; Sep2023, Vol. 15 Issue 17, p4379, 25p

Subject Terms: PAPILLOMAVIRUSES, CYTOKINES, SEQUENCE analysis, ANIMAL experimentation, OROPHARYNGEAL cancer, HEAD & neck cancer, CELL receptors, RNA, MACROPHAGES, GENE expression, CELLULAR signal transduction, RESEARCH funding, SQUAMOUS cell carcinoma, MICE, EPIGENOMICS

A phase 1b single-arm trial of intratumoral oncolytic virus V937 in combination with pembrolizumab in patients with advanced melanoma: results from the CAPRA study.

Authors: Silk, Ann W., O'Day, Steven J., Kaufman, Howard L., Bryan, Jennifer, Norrell, Jacqueline T., Imbergamo, Casey, Portal, Daniella, Zambrano-Acosta, Edwin, Palmeri, Marisa, Fein, Seymour, Wu, Cai, Guerreiro, Leslie, Medina, Daniel, Bommareddy, Praveen K., Zloza, Andrew, Fox, Bernard A., Ballesteros-Merino, Carmen, Ren, Yixin, Shafren, Darren, Grose, Mark

Source: Cancer Immunology, Immunotherapy; Jun2023, Vol. 72 Issue 6, p1405-1415, 11p

Subject Terms: ADVERSE health care events, PEMBROLIZUMAB, MELANOMA, T cells, TUMOR microenvironment

PD-L1 expression with immune-infiltrate evaluation and outcome prediction in melanoma patients treated with ipilimumab

Authors: Madonna, Gabriele, Ballesteros-Merino, Carmen, Feng, Zipei, Bifulco, Carlo, Capone, Mariaelena, Giannarelli, Diana, Mallardo, Domenico, Simeone, Ester, Grimaldi, Antonio M., Caracò, Corrado, Botti, Gerardo, Fox, Bernard A., Ascierto, Paolo A.

Source: Oncoimmunology. 7(12)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100077196966.0x000001&indx=1&recIds=ETOCvdc_100077196966.0x000001

Differential subcellular localization of SK3-containing channels in the hippocampus.

Authors: Ballesteros‐Merino, Carmen¹, Watanabe, Masahiko², Shigemoto, Ryuichi³, Fukazawa, Yugo³, Adelman, John P.⁴, Luján, Rafael¹

Source: European Journal of Neuroscience. Mar2014, Vol. 39 Issue 6, p883-892. 10p.

Subject Terms: *CALCIUM-dependent potassium channels, *HIPPOCAMPUS (Brain), *NEUROPLASTICITY, *MEMORY, *GENE expression, *WESTERN immunoblotting, *IMMUNOHISTOCHEMISTRY

Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells.

Authors: Duhen, Rebekka, Ballesteros-Merino, Carmen, Frye, Alexandra K., Tran, Eric, Rajamanickam, Venkatesh, Chang, Shu-Ching, Koguchi, Yoshinobu, Bifulco, Carlo B., Bernard, Brady, Leidner, Rom S., Curti, Brendan D., Fox, Bernard A., Urba, Walter J., Bell, R. Bryan, Weinberg, Andrew D.

Source: Nature Communications; 2/16/2021, Vol. 12 Issue 1, p1-14, 14p

Subject Terms: SQUAMOUS cell carcinoma, HEAD & neck cancer, LYMPHOCYTE subsets, BLOOD cells, HEMATOMA, T cells

Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer.

Authors: Gunderson, Andrew J., Rajamanickam, Venkatesh, Bui, Cynthia, Bernard, Brady, Pucilowska, Joanna, Ballesteros-Merino, Carmen, Schmidt, Mark, McCarty, Kayla, Philips, Michaela, Piening, Brian, Dubay, Christopher, Medler, Terry, Newell, Phillipa, Hansen, Paul, Tran, Eric, Tang, Ephraim, Bifulco, Carlo, Crittenden, Marka, Gough, Michael, Young, Kristina H.

Source: OncoImmunology; 2021, Vol. 10 Issue 1, p1-16, 16p

Subject Terms: GERMINAL centers, HUMORAL immunity, TERTIARY structure, MELANOMA, PANCREATIC cancer, IMMUNOLOGIC memory, PSYCHONEUROIMMUNOLOGY, HYPERCOAGULATION disorders

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TP53 Abnormalities Correlate with Immune Infiltration and Associate with Response to Flotetuzumab Immunotherapy in Acute Myeloid Leukemia

Authors: Lai, Catherine, Vadakekolathu, Jayakumar ^*, Reeder, Stephen ^*, Church, Sarah E. ^*, Ballesteros-Merino, Carmen ^*, Aldoss, Ibrahim, Advani, Anjali S, Godwin, John E., Wieduwilt, Matthew J., Arellano, Martha L., Uy, Geoffrey L, Ravandi, Farhad, Foster, Matthew C, Gyan, Emmanuel, Stiff, Patrick J., Vey, Norbert, Emadi, Ashkan, Carrabba, Matteo Giovanni ^*, Walter, Roland B., Sayre, Peter H., Tran, Kathy ^*, Timmeny, Erin ^*, Rettig, Michael P., Kaminker, Patrick ^*, Muth, John ^*, Guo, Kuo ^*, Yau, Tung On ^*, Valk, Peter J.M., Lowenberg, Bob, Gojo, Ivana, Bornhäuser, Martin ^*, DiPersio, John F., Davidson-Moncada, Jan K, Rutella, Sergio

Source: In Blood 5 November 2020 136 Supplement 1:3-4

Impact of moderate prenatal alcohol exposure on histaminergic neurons, histidine decarboxylase levels and histamine H2 receptors in adult rat offspring.

Authors: Davies, Suzy¹ (AUTHOR), Ballesteros-Merino, Carmen¹ (AUTHOR), Allen, Nyika A.¹ (AUTHOR), Porch, Morgan W.¹ (AUTHOR), Pruitt, Morgan E.¹ (AUTHOR), Christensen, Kyle H.¹ (AUTHOR), Rosenberg, Martina J.¹ (AUTHOR), Savage, Daniel D.¹ (AUTHOR) dsavage@salud.unm.edu

Source: Alcohol. May2019, Vol. 76, p47-57. 11p.

Subject Terms: *LABORATORY rats, *HYPOTHALAMUS, *HISTAMINE receptors, *LONG-term potentiation, *NEURONS, *DENTATE gyrus, *ANIMALS, *CELL receptors, *CEREBELLUM, *ENZYMES, *FRONTAL lobe, *HIPPOCAMPUS (Brain), *HISTAMINE, *QUESTIONNAIRES, *RADIOISOTOPES in medical diagnosis, *RATS, *CYTOMETRY, *PRENATAL exposure delayed effects, *IMPACT of Event Scale

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Flotetuzumab (FLZ), an Investigational CD123 x CD3 Bispecific Dart® Protein-Induced Clustering of CD3+ T Cells and CD123+ AML Cells in Bone Marrow Biopsies Is Associated with Response to Treatment in Primary Refractory AML Patients

Authors: Godwin, John E., Ballesteros-Merino, Carmen ^*, Lonberg, Nikhil ^*, Jensen, Shawn ^*, Moudgil, Tarsem ^*, Bifulco, Carlo B ^*, Wigginton, Jon, Muth, John ^*, Davidson-Moncada, Jan K, Fox, Bernard ^*

Source: In Blood 13 November 2019 134 Supplement 1:1410-1410