Benchmarking docking, density functional theory and molecular dynamics studies to assess the aldose reductase inhibitory potential of Trigonella foenum-graecum compounds for managing diabetes-associated complications

Authors: Mohammed Albratty, Neelaveni Thangavel, Balakumar Chandrasekaran, Abdulkarim M. Meraya, Hassan Ahmad Alhazmi, Sankar Muthumanickam, Pandi Boomi, Natarajan Boopala Bhagavan, Safaa F. Saleh

Source: Pharmacia, Vol 71, Iss , Pp 1-10 (2024)

Subject Terms: Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://pharmacia.pensoft.net/article/118949/download/pdf/; https://pharmacia.pensoft.net/article/118949/download/xml/; https://pharmacia.pensoft.net/article/118949/; https://doaj.org/toc/2603-557X

Access URL: https://doaj.org/article/502e3d8ec89a40e78ee05d914c83a93c

Synthesis, Anticancer Screening, and In Silico Evaluations of Thieno[2,3-c]pyridine Derivatives as Hsp90 Inhibitors

Authors: Balakumar Chandrasekaran, Mohammad F. Bayan, Ali Hmedat, Bilal A. Al-Jaidi, Deniz M. Al-Tawalbeh, Duaa Abuarqoub, Anas J. Rasras, Da’san M. M. Jaradat, Abdel Naser Dakkah, Wafa Hourani, Rajshekhar Karpoormath

Source: Pharmaceuticals, Vol 18, Iss 2, p 153 (2025)

Subject Terms: Hsp90, anticancer agents, thieno[2,3-c]pyridines, cell cycle analysis, molecular docking, ADME prediction, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/18/2/153; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/af027950f2ac406aaff94301baf04560

Editorial: Pharmacological and biochemical perspectives of kinase inhibitors in cancer and COVID-19 therapeutics

Authors: Balakumar Chandrasekaran, Muthupandian Saravanan

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: COVID-19, kinase inhibitors, cancer, hepatocellular carcinoma, JAKs, FDA, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1229673/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/2e0fb99f80ae4127adb74e25b87740c0

Therapeutic implications of current Janus kinase inhibitors as anti-COVID agents: A review

Authors: Nem Kumar Jain, Mukul Tailang, Hemant Kumar Jain, Balakumar Chandrasekaran, Biswa Mohan Sahoo, Anandhalakshmi Subramanian, Neelaveni Thangavel, Afaf Aldahish, Kumarappan Chidambaram, M. Alagusundaram, Santosh Kumar, Palani Selvam

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: Janus kinase, JAKs, JAK-STAT pathway, JAKi, Jakinibs, kinase inhibitors, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1135145/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/e8ed95bebb81434ba99fd334b94fd17b

Synthesis, pharmacological evaluation, and molecular modeling studies of novel isatin hybrids as potential anticancer agents

Authors: Rajapandi Raju, Kumarappan Chidambaram, Balakumar Chandrasekaran, Mohammad F. Bayan, Tapan Kumar Maity, Abdullah M. Alkahtani, Harish C Chandramoorthy

Source: Journal of Saudi Chemical Society, Vol 27, Iss 2, Pp 101598- (2023)

Subject Terms: Isatin-pyrimidine hybrid, Antiproliferative activity, Breast cancer cell (MCF-7), Dalton’s ascitic lymphoma (DAL), Molecular docking, Chemistry, QD1-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1319610323000029; https://doaj.org/toc/1319-6103

Access URL: https://doaj.org/article/bac5222bdfee4892997a7bcb04780389

Development and Characterization of Econazole Topical Gel

Authors: Mohammad F. Bayan, Balakumar Chandrasekaran, Mohammad H. Alyami

Source: Gels, Vol 9, Iss 12, p 929 (2023)

Subject Terms: econazole, cutaneous candidiasis, Carbopol® 940, topical gel, sustainability, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65

File Description: electronic resource

Relation: https://www.mdpi.com/2310-2861/9/12/929; https://doaj.org/toc/2310-2861

Access URL: https://doaj.org/article/df37512b0a2c4d999f1cc8ecc05618c2

Appraising the therapeutical potentials of Alchornea laxiflora (Benth.) Pax & K. Hoffm., an underexplored medicinal herb: A systematic review

Authors: Nem Kumar Jain, Mukul Tailang, Santosh Kumar, Balakumar Chandrasekaran, Yahia Alghazwani, Harish C. Chandramoorthy, Ashish Kumar, Hemali Deshpande, Pranay Wal, Manickam Balamurugan, Kumarappan Chidambaram

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: Alchornea laxiflora, ethnopharmacology, African plants, traditional medicine, phytochemistry, pharmacology, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.958453/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/a49173a36e74456e84f10c4adc363690

Development and Characterization of Gel-Based Buccoadhesive Bilayer Formulation of Nifedipine

Authors: M. Alagusundaram, Nem Kumar Jain, M. Yasmin Begum, S. Angala Parameswari, Vinod Kumar Nelson, Mohammad F. Bayan, Balakumar Chandrasekaran

Source: Gels, Vol 9, Iss 9, p 688 (2023)

Subject Terms: nifedipine, buccoadhesive, triggered delivery, ex vivo permeation, polymeric gel, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65

File Description: electronic resource

Relation: https://www.mdpi.com/2310-2861/9/9/688; https://doaj.org/toc/2310-2861

Access URL: https://doaj.org/article/a12fca8ad33e41eca25f571b8aea2bae

Editorial: Pharmacological and Biochemical Perspectives of Kinase Inhibitors in Cancer and COVID-19 Therapeutics, Volume I

Authors: Balakumar Chandrasekaran, Muthupandian Saravanan

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: COVID-19, kinase inhibitors, CDK, ligand-based and structure-based drug design, pharmacology, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.916324/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/5de03024f1aa41bb89b12850f2a5dd35

Combating Microbial Infections Using Metal-Based Nanoparticles as Potential Therapeutic Alternatives

Authors: Rajwinder Kaur, Kirandeep Kaur, Mohammad H. Alyami, Damanpreet Kaur Lang, Balraj Saini, Mohammad F. Bayan, Balakumar Chandrasekaran

Source: Antibiotics, Vol 12, Iss 5, p 909 (2023)

Subject Terms: metals, nanoparticles, antimicrobial action, microbicidal, biofilm formation inhibitors, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/12/5/909; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/9be53ce9f2e847fcb6578f66c1d9137b

Development of a Polyherbal Topical Gel for the Treatment of Acne

Authors: Benedict Jose Chellathurai, Ramyadevi Anburose, Mohammad H. Alyami, Mohan Sellappan, Mohammad F. Bayan, Balakumar Chandrasekaran, Kumarappan Chidambaram, Mohamed Rahamathulla

Source: Gels, Vol 9, Iss 2, p 163 (2023)

Subject Terms: Aloe barbadensis, Vigna radiata, Carbopol 940, polyherbal gel, acne, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65

File Description: electronic resource

Relation: https://www.mdpi.com/2310-2861/9/2/163; https://doaj.org/toc/2310-2861

Access URL: https://doaj.org/article/ce33b85e637a46e398fe087b1cae1544

In silico Screening of Natural Phytocompounds Towards Identification of Potential Lead Compounds to Treat COVID-19

Authors: Muthumanickam Sankar, Balajee Ramachandran, Boomi Pandi, Nachiappan Mutharasappan, Vidhyavathi Ramasamy, Poorani Gurumallesh Prabu, Gowrishankar Shanmugaraj, Yao Wang, Brintha Muniyandai, Subaskumar Rathinasamy, Balakumar Chandrasekaran, Mohammad F. Bayan, Jeyakanthan Jeyaraman, Gurumallesh Prabu Halliah, Solomon King Ebenezer

Source: Frontiers in Molecular Biosciences, Vol 8 (2021)

Subject Terms: COVID-19, main protease, molecular dynamics simulation, natural medicinal plants, S-ACE2, structure-based virtual screening, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.637122/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/b69cf5efd4b049a89b4475915d4bf629

Prospective Role of Peptide-Based Antiviral Therapy Against the Main Protease of SARS-CoV-2

Authors: Shafi Mahmud, Gobindo Kumar Paul, Suvro Biswas, Shamima Afrose, Mohasana Akter Mita, Md. Robiul Hasan, Mst. Sharmin Sultana Shimu, Alomgir Hossain, Maria Meha Promi, Fahmida Khan Ema, Kumarappan Chidambaram, Balakumar Chandrasekaran, Ali M. Alqahtani, Talha Bin Emran, Md. Abu Saleh

Source: Frontiers in Molecular Biosciences, Vol 8 (2021)

Subject Terms: SARS-CoV-2, COVID-19, M Pro, peptides, molecular dynamics, in silico, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.628585/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/55dbe76d764349329b3f7babf01ce824

Developmental Landscape of Potential Vaccine Candidates Based on Viral Vector for Prophylaxis of COVID-19

Authors: Rajashri Bezbaruah, Pobitra Borah, Bibhuti Bhushan Kakoti, Nizar A. Al-Shar’I, Balakumar Chandrasekaran, Da’san M. M. Jaradat, Munir A. Al-Zeer, Saeid Abu-Romman

Source: Frontiers in Molecular Biosciences, Vol 8 (2021)

Subject Terms: COVID-19, vaccines, viral vector, ChAdOx1-S, Ad5-nCoV, MERS-CoV, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.635337/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/491d5e8fa38f455abf76016493893f58

Emerging Therapeutic Approaches to Combat COVID-19: Present Status and Future Perspectives

Authors: Karthik Vivekanandhan, Poornima Shanmugam, Hamed Barabadi, Vigneshwaran Arumugam, Dharun Daniel Raj Daniel Paul Raj, Manikandan Sivasubramanian, Subbaiya Ramasamy, Krishnan Anand, Pandi Boomi, Balakumar Chandrasekaran, Selvaraj Arokiyaraj, Muthupandian Saravanan

Source: Frontiers in Molecular Biosciences, Vol 8 (2021)

Subject Terms: COVID-19, SARS-CoV-2, therapeutics, antiviral drugs, vaccines, nano-based approaches, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.604447/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/14ae668ea8fa4c3e88da8f1163da38d4

Perspectives on RNA Vaccine Candidates for COVID-19

Authors: Pobitra Borah, Pran Kishore Deb, Nizar A. Al-Shar’i, Lina A. Dahabiyeh, Katharigatta N. Venugopala, Vinayak Singh, Pottathil Shinu, Snawar Hussain, Satyendra Deka, Balakumar Chandrasekaran, Da’san M. M. Jaradat

Source: Frontiers in Molecular Biosciences, Vol 8 (2021)

Subject Terms: COVID-19, SARS-CoV-2, mRNA, self-amplifying RNA, vaccine, conventional RNA, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.635245/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/436c2bebdae14321991a8bd13fee9c3c

Neurological Consequences of SARS-CoV-2 Infection and Concurrence of Treatment-Induced Neuropsychiatric Adverse Events in COVID-19 Patients: Navigating the Uncharted

Authors: Pobitra Borah, Pran Kishore Deb, Balakumar Chandrasekaran, Manoj Goyal, Monika Bansal, Snawar Hussain, Pottathil Shinu, Katharigatta N. Venugopala, Nizar A. Al-Shar’i, Satyendra Deka, Vinayak Singh

Source: Frontiers in Molecular Biosciences, Vol 8 (2021)

Subject Terms: COVID - 19, SARS – CoV – 2, neurotropism, nervous system, neurologic manifestations, psychological impact, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.627723/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/0953f66fe2674df68eff68817c8341a2

One-step synthesis of picolinohydrazides from fusaric acid: DFT, structural characterization and molecular inhibitory studies on metastatic tumor-derived exosomal and non-exosomal proteins

Authors: Anand, Krishnan, Ramesh, Muthusamy, Singh, Thishana, Balakumar, Chandrasekaran, Chithravel, Vadivalagan, Prasher, Parteek, Katari, Naresh Kumar, Gupta, Gaurav, Singh, Sachin Kumar, Chellappan, Dinesh Kumar, Dua, Kamal, Chavda, Vivek, Laishevtcev, Alexey, Shahbaaz, Mohd, Abdellattif, Magda H., Saravanan, Muthupandian, Chuturgoon, Anil A.

Source: In Journal of Molecular Structure 5 May 2022 1255

Ligand- and structure-based in silico studies to identify kinesin spindle protein (KSP) inhibitors as potential anticancer agents

Authors: Balakumar, Chandrasekaran, Ramesh, Muthusamy, Tham, Chuin Lean, Khathi, Samukelisiwe Pretty, Kozielski, Frank, Srinivasulu, Cherukupalli, Hampannavar, Girish A., Sayyad, Nisar, Soliman, Mahmoud E., Karpoormath, Rajshekhar

Source: Journal of biomolecular structure & dynamics. 36(14):3687-3704

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100078515176.0x000001&indx=1&recIds=ETOCvdc_100078515176.0x000001

Green biosynthesis of gold nanoparticles using Croton sparsiflorus leaves extract and evaluation of UV protection, antibacterial and anticancer applications

Authors: Boomi, Pandi, Poorani, Gurumallesh Prabu, Selvam, Samayanan, Palanisamy, Subramanian, Jegatheeswaran, Sonamuthu, Anand, Krishnan, Balakumar, Chandrasekaran, Premkumar, Kumpati, Prabu, Halliah Gurumallesh

Source: Applied organometallic chemistry. 34(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107035534.0x000001&indx=1&recIds=ETOCvdc_100107035534.0x000001