KDM5A/B contribute to HIV-1 latent infection and survival of HIV-1 infected cells

Authors: Li, Tai-Wei, Park, Youngmin, Watters, Emily G., Wang, Xu, Zhou, Dawei, Fiches, Guillaume N., Wu, Zhenyu, Badley, Andrew D., Sacha, Jonah B., Ho, Wen-Zhe, Santoso, Netty G., Qi, Jun, Zhu, Jian

Source: In Antiviral Research August 2024 228

Longitudinal laboratory testing tied to PCR diagnostics in COVID-19 patients reveals temporal evolution of distinctive coagulopathy signatures

Authors: Pawlowski, Colin, Wagner, Tyler, Puranik, Arjun, Murugadoss, Karthik, Loscalzo, Liam, Venkatakrishnan, AJ, Pruthi, Rajiv K., Houghton, Damon E., OHoro, John C., Morice II, William G., Halamka, John, Badley, Andrew D., Barnathan, Elliot S., Makimura, Hideo, Khan, Najat, Soundararajan, Venky

Subject Terms: Physics - Medical Physics, Electrical Engineering and Systems Science - Image and Video Processing, Quantitative Biology - Quantitative Methods

Access URL: http://arxiv.org/abs/2005.10938

Augmented Curation of Unstructured Clinical Notes from a Massive EHR System Reveals Specific Phenotypic Signature of Impending COVID-19 Diagnosis

Authors: Shweta, FNU, Murugadoss, Karthik, Awasthi, Samir, Venkatakrishnan, AJ, Puranik, Arjun, Kang, Martin, Pickering, Brian W., O'Horo, John C., Bauer, Philippe R., Razonable, Raymund R., Vergidis, Paschalis, Temesgen, Zelalem, Rizza, Stacey, Mahmood, Maryam, Wilson, Walter R., Challener, Douglas, Anand, Praveen, Liebers, Matt, Doctor, Zainab, Silvert, Eli, Solomon, Hugo, Wagner, Tyler, Gores, Gregory J., Williams, Amy W., Halamka, John, Soundararajan, Venky, Badley, Andrew D.

Subject Terms: Computer Science - Machine Learning, Computer Science - Information Retrieval, Quantitative Biology - Quantitative Methods

Access URL: http://arxiv.org/abs/2004.09338

Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in patients with severe COVID-19

Authors: Wu, Xiaosheng ^{1, 7, ∗}, Manske, Michelle K. ¹, Ruan, Gordon J. ¹, Witter, Taylor L. ², Nowakowski, Kevin E. ¹, Abeykoon, Jithma P. ¹, Tang, Xinyi ¹, Yu, Yue ³, Gwin, Kimberly A. ¹, Wu, Annie ⁴, Taupin, Vanessa ⁵, Bhardwaj, Vaishali ¹, Paludo, Jonas ¹, Dasari, Surendra ³, Dong, Haidong ⁴, Ansell, Stephen M. ¹, Badley, Andrew D. ⁶, Schellenberg, Matthew J. ², Witzig, Thomas E. ^{1, ∗∗}

Source: In iScience 16 June 2023 26(6)

Development of a multiomics model for identification of predictive biomarkers for COVID-19 severity: a retrospective cohort study

Authors: Byeon, Seul Kee, Madugundu, Anil K, Garapati, Kishore, Ramarajan, Madan Gopal, Saraswat, Mayank, Kumar-M, Praveen, Hughes, Travis, Shah, Rameen, Patnaik, Mrinal M, Chia, Nicholas, Ashrafzadeh-Kian, Susan, Yao, Joseph D, Pritt, Bobbi S, Cattaneo, Roberto, Salama, Mohamed E, Zenka, Roman M, Kipp, Benjamin R, Grebe, Stefan K G, Singh, Ravinder J, Sadighi Akha, Amir A, Algeciras-Schimnich, Alicia, Dasari, Surendra, Olson, Janet E, Walsh, Jesse R, Venkatakrishnan, A J, Jenkinson, Garrett, O'Horo, John C, Badley, Andrew D, Pandey, Akhilesh ^*

Source: In The Lancet Digital Health September 2022 4(9):e632-e645

Lenzilumab in hospitalised patients with COVID-19 pneumonia (LIVE-AIR): a phase 3, randomised, placebo-controlled trial

Authors: Lewis, Meghan, Sher, Linda, Bowdish, Michael, Wald-Dickler, Noah, Biswas, Subarna, Lam, Lydia, Vo, Khang, Poblete, Roy, Lee, May M., Hutcheon, Douglass, Patron, Roberto, Gharbin, John, Moran, Caitlin, Kandiah, Sheetal, Cantos, Valeria, Rebolledo, Paulina, del Rio, Carlos, Lennox, Jeffrey, Polito, Carmen, Sheth, Anandi, Patel, Anup, Paniagua, Homero, Yohannes, Seife, Amin, Alpesh, Lee, Richard, Watanabe, Miki, Hsieh, Lanny, Cearras, Martin, Parikh, Amay, Sniffen, Jason, Onyia, Wilfred, Boger, Michael, Davidson, Lisa, Gajurel, Kiran, Leonard, Michael, McCurdy, Lewis, Quezada, Nestor, Sampson, Mindy, Shahid, Zainab, Strollo, Stephanie, Weinrib, David, Zulfigar, Sara, McDonald, Cheryl, Hollingsworth, John, Burk, John, Berg, Joshua, Barbaro, Daniel, Miller, Andrew, Sambathkumar, Lakshmi, McDonald, Stuart, Okoye, Obinna, Pulido, Juan, Fulton, Jennifer, Gill, William, Zuckerman, Richard, Lewis, Lionel, Mandapakala, Chaitanya, Robinson, Matthew, Metzger, Brian, Alam, Maqsood, Politis, Chrisoula, Frosch, Anne, Ngo, Linh, Carvalho Neuenschwander, Fernando, Figueiredo, EstevÃo, CanÇado, Gualter, Araujo, Gustavo, GuimarÃes, Lucas, Diaz, Ricardo, Bacellar, Natalia, Silva, Celso, Ferreira, Paulo, Andrade Lima, Marina, Uber Ghisi, Caroline, Anton, Camila, Albaneze, Ricardo, Wagner de Castro Lima Santos, Daniel, Iglessias, Ana Caroline, Lago, Marianna, Pietrobom, Paula, Alves, Maysa, Duailibe Furtado, Juvencio José, Trevelin, Leopoldo, Telles, Valeria, Correa, Francini, Ramos, Fabiano, de A. R. Da Silva, Marina, Lacerda Garcia, Rebeca C., Maldonado, Ana Elizabeth G., Beheregaray, Ana Carolina M., Ortiz, Ana Maria T., Luz, Kleber, Pipolo Milan, Eveline, Soares de Castro, Janine, Barbosa Moreira, Matheus José, Bezerra Onofre, Renata, do Nascimento JÁcome, TÁcito, Barreto Garcia, Victor, Rolim de Souzafrom, Victor Matheus, Dal Pizzol, Felipe, Ritter, Cristiane, Vinhas, Marcelo B., Westheimer Cavalcante, Adilson Joaquim, Minghini, Julia, Dorigo, Loni, Salgado Miranda, Marina, Antila, Martti Anton, Brugnolli, Rebeca, Antila, Henrikki, Temesgen, Zelalem ^*, Burger, Charles D, Baker, Jason, Polk, Christopher, Libertin, Claudia R, Kelley, Colleen F, Marconi, Vincent C, Orenstein, Robert, Catterson, Victoria M, Aronstein, William S, Durrant, Cameron, Chappell, Dale, Ahmed, Omar, Chappell, Gabrielle, Badley, Andrew D

Source: In The Lancet Respiratory Medicine March 2022 10(3):237-246

The Female-Predominant Persistent Immune Dysregulation of the Post-COVID Syndrome

Authors: Ganesh, Ravindra, Grach, Stephanie L., Ghosh, Aditya K., Bierle, Dennis M., Salonen, Bradley R., Collins, Nerissa M., Joshi, Avni Y., Boeder, Neal D., Jr., Anstine, Christopher V., Mueller, Michael R., Wight, Elizabeth C., Croghan, Ivana T., Badley, Andrew D., Carter, Rickey E., Hurt, Ryan T.

Source: In Mayo Clinic Proceedings March 2022 97(3):454-464

Comparative effectiveness of mRNA-1273 and BNT162b2 against symptomatic SARS-CoV-2 infection

Authors: Puranik, Arjun, Lenehan, Patrick J., Silvert, Eli, Niesen, Michiel J.M., Corchado-Garcia, Juan, O’Horo, John C., Virk, Abinash, Swift, Melanie D., Gordon, Joel E., Speicher, Leigh Lewis, Geyer, Holly L., Kremers, Walter, Halamka, John, Badley, Andrew D., Venkatakrishnan, A.J., Soundararajan, Venky

Source: In Med 14 January 2022 3(1):28-41

Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo

Authors: Cummins, Nathan W, Baker, Jason, Chakraborty, Rana, Dean, Patrick G, Garcia-Rivera, Enrique, Krogman, Ashton, Kumar, Shaji, Kuzmichev, Yury V, Laird, Gregory M, Landay, Alan, Lichterfeld, Mathias, Mahmood, Maryam, Martinson, Jeffrey, Maynes, Mark, Natesampillai, Sekar, Rajkumar, Vincent, Rassadkina, Yelizaveta, Ritter, Kristen D., Rivera, Christina G, Rizza, Stacey A, Subramanian, Krupa, Tande, Aaron J, Wonderlich, Elizabeth R, Whitaker, Jennifer A, Zeuli, John, Badley, Andrew D

Source: In eClinicalMedicine December 2021 42

Casirivimab–Imdevimab treatment is associated with reduced rates of hospitalization among high-risk patients with mild to moderate coronavirus disease-19

Authors: Razonable, Raymund R., Pawlowski, Colin, O'Horo, John C., Arndt, Lori L., Arndt, Richard, Bierle, Dennis M., Borgen, Molly Destro, Hanson, Sara N., Hedin, Michelle C., Lenehan, Patrick, Puranik, Arjun, Seville, Maria T, Speicher, Leigh L., Tulledge-Scheitel, Sidna M., Venkatakrishnan, AJ, Wilker, Caroline G., Badley, Andrew D., Ganesh, Ravindra

Source: In EClinicalMedicine October 2021 40

Cerebral Venous Sinus Thrombosis is not Significantly Linked to COVID-19 Vaccines or Non-COVID Vaccines in a Large Multi-State Health System

Authors: Pawlowski, Colin, Rincón-Hekking, John, Awasthi, Samir, Pandey, Viral, Lenehan, Patrick, Venkatakrishnan, AJ, Bade, Sairam, O'Horo, John C., Virk, Abinash, Swift, Melanie D., Williams, Amy W., Gores, Gregory J., Badley, Andrew D., Halamka, John, Soundararajan, Venky

Source: In Journal of Stroke and Cerebrovascular Diseases October 2021 30(10)

Acute Kidney Injury in Severe COVID-19 Has Similarities to Sepsis-Associated Kidney Injury: A Multi-Omics Study

Authors: Alexander, Mariam P., Mangalaparthi, Kiran K., Madugundu, Anil K., Moyer, Ann M., Adam, Benjamin A., Mengel, Michael, Singh, Smrita, Herrmann, Sandra M., Rule, Andrew D., Cheek, E. Heidi, Herrera Hernandez, Loren P., Graham, Rondell P., Aleksandar, Denic, Aubry, Marie-Christine, Roden, Anja C., Hagen, Catherine E., Quinton, Reade A., Bois, Melanie C., Lin, Peter T., Maleszewski, Joseph J., Cornell, Lynn D., Sethi, Sanjeev, Pavelko, Kevin D., Charlesworth, Jon, Narasimhan, Ramya, Larsen, Christopher P., Rizza, Stacey A., Nasr, Samih H., Grande, Joseph P., McKee, Trevor D., Badley, Andrew D., Pandey, Akhilesh, Taner, Timucin

Source: In Mayo Clinic Proceedings October 2021 96(10):2561-2575

FDA-authorized mRNA COVID-19 vaccines are effective per real-world evidence synthesized across a multi-state health system

Authors: Pawlowski, Colin, Lenehan, Patrick, Puranik, Arjun, Agarwal, Vineet, Venkatakrishnan, A.J., Niesen, Michiel J.M., O’Horo, John C., Virk, Abinash, Swift, Melanie D., Badley, Andrew D., Halamka, John, Soundararajan, Venky

Source: In Med 13 August 2021 2(8):979-992

Real-time analysis of a mass vaccination effort confirms the safety of FDA-authorized mRNA COVID-19 vaccines

Authors: McMurry, Reid, Lenehan, Patrick, Awasthi, Samir, Silvert, Eli, Puranik, Arjun, Pawlowski, Colin, Venkatakrishnan, A.J., Anand, Praveen, Agarwal, Vineet, O’Horo, John C., Gores, Gregory J., Williams, Amy W., Badley, Andrew D., Halamka, John, Virk, Abinash, Swift, Melanie D., Carlson, Katie, Doddahonnaiah, Deeksha, Metzger, Anna, Kayal, Nikhil, Berner, Gabi, Ramudu, Eshwan, Carpenter, Corinne, Wagner, Tyler, Rajasekharan, Ajit, Soundararajan, Venky

Source: In Med 13 August 2021 2(8):965-978

Anemia during SARS-CoV-2 infection is associated with rehospitalization after viral clearance

Authors: Lenehan, Patrick J., Ramudu, Eshwan, Venkatakrishnan, A.J., Berner, Gabriela, McMurry, Reid, O'Horo, John C., Badley, Andrew D., Morice, William, II, Halamka, John, Soundararajan, Venky

Source: In iScience 23 July 2021 24(7)

A Blueprint to Control the SARS-CoV-2 Pandemic

Authors: O’Horo, John C., Williams, Amy W., Badley, Andrew D.

Source: In Mayo Clinic Proceedings May 2021 96(5):1128-1131

Pre-existing conditions are associated with COVID-19 patients’ hospitalization, despite confirmed clearance of SARS-CoV-2 virus

Authors: Pawlowski, Colin, Venkatakrishnan, AJ, Ramudu, Eshwan, Kirkup, Christian, Puranik, Arjun, Kayal, Nikhil, Berner, Gabriela, Anand, Akash, Barve, Rakesh, O'Horo, John C., Badley, Andrew D., Soundararajan, Venky

Source: In EClinicalMedicine April 2021 34

Association Between Chronic Statin Use and 30-Day Mortality in Hospitalized Patients With COVID-19

Authors: Yetmar, Zachary A., Challener, Douglas W., Tleyjeh, Imad M., Sohail, M. Rizwan, Cerhan, James R., Badley, Andrew D., O’Horo, John C.

Source: In Mayo Clinic Proceedings: Innovations, Quality & Outcomes April 2021 5(2):442-446

The Yin and Yang of SARS-CoV-2 Mutation and Evolution

Authors: Badley, Andrew D.

Source: In Mayo Clinic Proceedings April 2021 96(4):863-865

Enoxaparin is associated with lower rates of mortality than unfractionated Heparin in hospitalized COVID-19 patients

Authors: Pawlowski, Colin, Venkatakrishnan, AJ, Kirkup, Christian, Berner, Gabriela, Puranik, Arjun, O'Horo, John C., Badley, Andrew D., Soundararajan, Venky

Source: In EClinicalMedicine March 2021 33