Hydroxyurea dose optimisation for children with sickle cell anaemia in sub-Saharan Africa (REACH): extended follow-up of a multicentre, open-label, phase 1/2 trial

Authors: Aygun, Banu ^*, Lane, Adam, Smart, Luke R, Santos, Brígida, Tshilolo, Léon, Williams, Thomas N, Olupot-Olupot, Peter, Stuber, Susan E, Tomlinson, George, Latham, Teresa, Ware, Russell E

Source: In The Lancet Haematology June 2024 11(6):e425-e435

Hydroxyurea treatment is associated with lower malaria incidence in children with sickle cell anemia in sub-Saharan Africa

Authors: Olupot-Olupot, Peter, Tomlinson, George, Williams, Thomas N., Tshilolo, Léon, Santos, Brígida, Smart, Luke R., McElhinney, Kathryn, Howard, Thad A., Aygun, Banu, Stuber, Susan E., Lane, Adam, Latham, Teresa S., Ware, Russell E. ^∗

Source: In Blood 23 March 2023 141(12):1402-1410

Cardiac complications of sickle cell disease in pediatric patients: A case report and contemporary literature review

Authors: Smerling, Jonathan, Burns, Joseph, Haimed, Abraham, Ganigara, Madhusudan, Appiah-Kubi, Abena O., Aygun, Banu, Mitchell, Elizabeth C., Dhar, Arushi

Source: In Progress in Pediatric Cardiology September 2022 66

Longitudinal analysis of cardiac abnormalities in pediatric patients with sickle cell anemia and effect of hydroxyurea therapy

Authors: Dhar, Arushi ^*, Leung, Tung Ming, Appiah-Kubi, Abena, Gruber, Dorota, Aygun, Banu, Serigano, Olivia, Mitchell, Elizabeth

Source: In Blood Advances 9 November 2021 5(21):4406-4412

Developmental screening of three‐year‐old children with sickle cell disease compared to controls

Authors: Wang, Winfred, Freeman, Molly, Hamilton, Latacha, Carroll, Yvonne, Kang, Guolian, Moen, Joseph, Smeltzer, Matthew P., Schreiber, Jane, Heitzer, Andrew M., Estepp, Jeremie, Aygun, Banu

Source: British journal of haematology. 195(4):621-628

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141591744.0x000001&indx=1&recIds=ETOCvdc_100141591744.0x000001

Safety and benefits of automated red cell depletion‐exchange compared to standard exchange in patients with sickle cell disease undergoing chronic transfusion

Authors: Ziemba, Yonah, Xu, Cindy, Fomani, Katayoun M., Nandi, Vijay, Yuan, Tiejun, Rehmani, Shiraz, Sachais, Bruce S., Appiah‐Kubi, Abena O., Aygun, Banu, Louie, James E., Shi, Patricia A.

Source: Transfusion. 61(2):526-536

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114876799.0x000001&indx=1&recIds=ETOCvdc_100114876799.0x000001

NT‐proBNP levels and cardiopulmonary function in children with sickle cell disease

Authors: Feld, Lance, Fiorino, Elizabeth K., Aygun, Banu, Appiah‐Kubi, Abena, Mitchell, Elizabeth C., Jackson, Stacey, Mehran, Roxana, Fishbein, Joanna, Santiago, Maria T.

Source: Pediatric pulmonology. 56(2):495-501

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114425001.0x000001&indx=1&recIds=ETOCvdc_100114425001.0x000001

Multisystem inflammatory syndrome in children (MIS‐C) and the prothrombotic state: Coagulation profiles and rotational thromboelastometry in a MIS‐C cohort

Authors: Al‐Ghafry, Maha, Vagrecha, Anshul, Malik, Marium, Levine, Chana, Uster, Eliza, Aygun, Banu, Appiah‐Kubi, Abena, Vlachos, Adrianna, Capone, Christine A., Rajan, Sujatha, Palumbo, Nancy, Misra, Nilanjana, Mitchell, Elizabeth C., Wolfe, Lawrence C., Lipton, Jeffrey M., Shore‐Lesserson, Linda, Acharya, Suchitra S.

Source: Journal of thrombosis and haemostasis. 19(7):1764-1770

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122923261.0x000001&indx=1&recIds=ETOCvdc_100122923261.0x000001

Clinical phenotypes of three children with sickle cell disease caused by HbS/Sicilian (δβ)0‐thalassemia deletion

Authors: Aygun, Banu, Bello, Adriana, Thompson, Alexis A., Davis, Lance, Sun, Yanan, Luo, Hong‐yuan, Cui, Shuaiying, Chui, David H. K.

Source: American journal of hematology. 97(4):E156-E158

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168204001.0x000001&indx=1&recIds=ETOCvdc_100168204001.0x000001

Documented Viral Illness at the Time of Splenic Sequestration Does Not Affect the Odds of Recurrence in Children With Sickle Cell Disease

Authors: Clement, Omoyeni, Fishbein, Joanna, Appiah-Kubi, Abena, Aygun, Banu

Source: Journal of pediatric hematology/oncology. 44(2):40-42

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155081192.0x000001&indx=1&recIds=ETOCvdc_100155081192.0x000001

Varying presentations and favourable outcomes of COVID‐19 infection in children and young adults with sickle cell disease: an additional case series with comparisons to published cases

Authors: Appiah‐Kubi, Abena, Acharya, Suchitra, Fein Levy, Carolyn, Vlachos, Adrianna, Ostovar, Gholamabbas, Murphy, Kristina, Farrell, Antonella, Brower, Donna, Lipton, Jeffrey M., Wolfe, Lawrence, Aygun, Banu

Source: British journal of haematology. 190(4):e221-e224

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122574485.0x000001&indx=1&recIds=ETOCvdc_100122574485.0x000001

Assessing multilevel barriers to hydroxyurea adherence in youth with sickle cell disease using pharmacy‐based refill records.

Authors: Smaldone, Arlene, Manwani, Deepa, Aygun, Banu, Appiah‐Kubi, Abena, Smith‐Whitley, Kim, Green, Nancy S.

Source: Pediatric Blood & Cancer; Sep2024, Vol. 71 Issue 9, p1-7, 7p

Health Supervision for Children and Adolescents With Sickle Cell Disease: Clinical Report.

Authors: Yates, Amber M.¹, Aygun, Banu², Nuss, Rachelle³, Rogers, Zora R.⁴ Zora.Rogers@UTSouthwestern.edu

Source: Pediatrics. Aug2024, Vol. 154 Issue 2, p1-18. 18p.

Subject Terms: *SUPERVISION of employees, *PATIENT education, *SICKLE cell anemia, *PRIMARY health care, *FAMILIES, *GENETIC counseling, *PEDIATRICS, *SOCIAL support, *HEALTH care teams

Lovo-cel (bb1111) Gene Therapy for Sickle Cell Disease (SCD): Updated Group C Clinical Results and Investigations into Two Cases of Anemia from the Phase 1/2 HGB-206 Study

Authors: Walters, Mark C., Thompson, Alexis A., Kwiatkowski, Janet L., Parikh, Suhag, Mapara, Markus Y., Rifkin-Zenenberg, Stacey, Aygun, Banu, Kasow, Kimberly A., Miller, Alex, Zhang, Lixin, Chawla, Anjulika, Macari, Elizabeth R., Pierciey, Francis J., Tisdale, John F., Kanter, Julie

Source: Transplantation and Cellular Therapy. 29(S):S288-S289

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180673146.0x000001&indx=1&recIds=ETOCvdc_100180673146.0x000001

Management of vaso‐occlusive episodes in the day hospital decreases admissions in children with sickle cell disease

Authors: Karkoska, Kristine, Appiah‐Kubi, Abena, Rocker, Joshua, Stoffels, Guillaume, Aygun, Banu

Source: British journal of haematology. 186(6):855-860

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100088877257.0x000001&indx=1&recIds=ETOCvdc_100088877257.0x000001

HABIT efficacy and sustainability trial, a multi-center randomized controlled trial to improve hydroxyurea adherence in youth with sickle cell disease: a study protocol

Authors: Smaldone, Arlene, Manwani, Deepa, Aygun, Banu, Smith-Whitley, Kim, Jia, Haomiao, Bruzzese, Jean-Marie, Findley, Sally, Massei, Joshua, Green, Nancy

Source: BMC pediatrics. 19(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190433237.0x000001&indx=1&recIds=ETOCvdc_100190433237.0x000001

Mental health assessment of youth with sickle cell disease and their primary caregivers during the COVID‐19 pandemic

Authors: Green, Nancy S., Manwani, Deepa, Smith‐Whitley, Kim, Aygun, Banu, Appiah‐Kubi, Abena, Smaldone, Arlene M.

Source: Pediatric blood & cancer. 69(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157119707.0x000001&indx=1&recIds=ETOCvdc_100157119707.0x000001

Reducing transfusion utilization for children with sickle cell anemia in sub‐Saharan Africa with hydroxyurea: Analysis from the phase I/II REACH trial.

Authors: Power‐Hays, Alexandra, Tomlinson, George A., Tshilolo, Leon, Santos, Brígida, Williams, Thomas N., Olupot‐Olupot, Peter, Smart, Luke R., Aygun, Banu, Lane, Adam, Stuber, Susan E., Latham, Teresa, Ware, Russell E.

Source: American Journal of Hematology; Apr2024, Vol. 99 Issue 4, p625-632, 8p

Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment (HABIT) efficacy trial: Community health worker support may increase hydroxyurea adherence of youth with sickle cell disease.

Authors: Green, Nancy S., Manwani, Deepa, Aygun, Banu, Appiah‐Kubi, Abena, Smith‐Whitley, Kim, Castillo, Yina, Soriano, Lucy, Jia, Haomiao, Smaldone, Arlene M.

Source: Pediatric Blood & Cancer; Apr2024, Vol. 71 Issue 4, p1-10, 10p

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia—TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial

Authors: Ware, Russell E ^*, Davis, Barry R, Schultz, William H, Brown, R Clark, Aygun, Banu, Sarnaik, Sharada, Odame, Isaac, Fuh, Beng, George, Alex, Owen, William, Luchtman-Jones, Lori, Rogers, Zora R, Hilliard, Lee, Gauger, Cynthia, Piccone, Connie, Lee, Margaret T, Kwiatkowski, Janet L, Jackson, Sherron, Miller, Scott T, Roberts, Carla, Heeney, Matthew M, Kalfa, Theodosia A, Nelson, Stephen, Imran, Hamayun, Nottage, Kerri, Alvarez, Ofelia, Rhodes, Melissa, Thompson, Alexis A, Rothman, Jennifer A, Helton, Kathleen J, Roberts, Donna, Coleman, Jamie, Bonner, Melanie J, Kutlar, Abdullah, Patel, Niren, Wood, John, Piller, Linda, Wei, Peng, Luden, Judy, Mortier, Nicole A, Stuber, Susan E, Luban, Naomi L C, Cohen, Alan R, Pressel, Sara, Adams, Robert J

Source: In The Lancet 13-19 February 2016 387(10019):661-670