Establishment of the auxin inducible degron system for Babesia duncani: a conditional knockdown tool to study precise protein regulation in Babesia spp.

Authors: Bo Chen, Qi Zhang, Sen Wang, Xing-ai Guan, Wan-xin Luo, Dong-fang Li, Yue He, Shu-jing Huang, Ya-ting Zhou, Jun-long Zhao, Lan He

Source: Parasites & Vectors, Vol 17, Iss 1, Pp 1-12 (2024)

Subject Terms: Babesia duncani, Conditional knockdown system, Auxin-inducible degron, Protein degradation, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1756-3305

Access URL: https://doaj.org/article/efecd796b72641bb9d320d31a351979f

Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism

Authors: Emily M. Pujadas Liwag, Xiaolong Wei, Nicolas Acosta, Lucas M. Carter, Jiekun Yang, Luay M. Almassalha, Surbhi Jain, Ali Daneshkhah, Suhas S. P. Rao, Fidan Seker-Polat, Kyle L. MacQuarrie, Joe Ibarra, Vasundhara Agrawal, Erez Lieberman Aiden, Masato T. Kanemaki, Vadim Backman, Mazhar Adli

Source: Genome Biology, Vol 25, Iss 1, Pp 1-42 (2024)

Subject Terms: Nuclear lamina, Auxin-inducible degron system, 3D chromatin organization, Lamin-associated domains, Topologically associated domains, Partial Wave Spectroscopic Microscopy, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/4305f5fcf633415aacff6d99aeabee41

HiHo-AID2: boosting homozygous knock-in efficiency enables robust generation of human auxin-inducible degron cells

Authors: Shiqian Li, Yafei Wang, Miesje van der Stoel, Xin Zhou, Shrinidhi Madhusudan, Kristiina Kanerva, Van Dien Nguyen, Nazli Eskici, Vesa M. Olkkonen, You Zhou, Taneli Raivio, Elina Ikonen

Source: Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)

Subject Terms: Auxin-inducible degron 2, Homology-directed repair enhancers, Homozygous knock-in, Functional inactivation, Chemogenetics, Human embryonic stem cell (hESC), Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/b386292dc07c45e88b124344bcaa5ff8

Auxin-inducible degron system: an efficient protein degradation tool to study protein function

Authors: Kundurthi Phanindhar, Rakesh K Mishra

Source: BioTechniques, Vol 74, Iss 4, Pp 186-198 (2023)

Subject Terms: auxin, auxin-inducible degron, degrons, model organisms, protein degradation, TIR1, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

Access URL: https://doaj.org/article/1209eaba01544e1fab1ca16d7e62ac33

Auxin-inducible degron 2 system deciphers functions of CTCF domains in transcriptional regulation

Authors: Judith Hyle, Mohamed Nadhir Djekidel, Justin Williams, Shaela Wright, Ying Shao, Beisi Xu, Chunliang Li

Source: Genome Biology, Vol 24, Iss 1, Pp 1-30 (2023)

Subject Terms: CTCF, Transcription, Auxin-inducible degron, CRISPR, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/653df8a9744f4e94aef44191fad0d353

EWSR1 prevents the induction of aneuploidy through direct regulation of Aurora B

Authors: Haeyoung Kim, Hyewon Park, Evan T. Schulz, Yoshiaki Azuma, Mizuki Azuma

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: mitosis, Aurora B, sarcoma, aneuploidy, chromosome mis-segregation, auxin inducible degron (AID) system, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.987153/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/0ddbbfbf64d24010b6277a5cbd7aab86

Erratum: Auxin-inducible degron system reveals temporal-spatial roles of HSF-1 and its transcriptional program in lifespan assurance

Authors: Frontiers Production Office

Source: Frontiers in Aging, Vol 3 (2022)

Subject Terms: aging, proteostasis, heat shock factor, auxin-inducible degron, temporal-spatial function, core chaperome, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fragi.2022.1006781/full; https://doaj.org/toc/2673-6217

Access URL: https://doaj.org/article/af40a8248bd84b5c86b293104d47bd0a

A One-step strategy to target essential factors with auxin-inducible degron system in mouse embryonic stem cells

Authors: Jingsheng Li, Chunhong Dai, Wenyan Xie, Heyao Zhang, Xin Huang, Constantinos Chronis, Ying Ye, Wensheng Zhang

Source: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Subject Terms: pluripotency, embryonic stem cells, chromatin modifiers, auxin-inducible degron, differentiation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.964119/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/925b0d0d461e43f8a34e3bfdbcb325d7

Auxin-Inducible Degron System Reveals Temporal-Spatial Roles of HSF-1 and Its Transcriptional Program in Lifespan Assurance

Authors: Allison C. Morphis, Stacey L. Edwards, Purevsuren Erdenebat, Lalit Kumar, Jian Li

Source: Frontiers in Aging, Vol 3 (2022)

Subject Terms: aging, proteostasis, heat shock factor, auxin-inducible degron, temporal-spatial function, core chaperome, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fragi.2022.899744/full; https://doaj.org/toc/2673-6217

Access URL: https://doaj.org/article/ceb9d3f889ae42cd8e9eb0a19de6ab82

Efficient Gene Knockout and Knockdown Systems in Neospora caninum Enable Rapid Discovery and Functional Assessment of Novel Proteins

Authors: Tiago W. P. Mineo, Jessica H. Chern, Amara C. Thind, Caroline M. Mota, Santhosh M. Nadipuram, Juan A. Torres, Peter J. Bradley

Source: mSphere, Vol 7, Iss 1 (2022)

Subject Terms: Neospora caninum, Toxoplasma gondii, Ku80, CRISPR/Cas9, dense granule, auxin-inducible degron, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/f3b2b63836244ecd8576478477290f30

Evaluation of the OsTIR1 and AtAFB2 AID Systems for Genome Architectural Protein Degradation in Mammalian Cells

Authors: Anastasia Yunusova, Alexander Smirnov, Tatiana Shnaider, Varvara Lukyanchikova, Svetlana Afonnikova, Nariman Battulin

Source: Frontiers in Molecular Biosciences, Vol 8 (2021)

Subject Terms: auxin-inducible degron (AID) system, CRISPR/Cas9, condensin, cohesin, mouse ES cells, HAP1 cells, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.757394/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/326ad3447e7448588d75862d96e9e9d8

Adaptation of the AID system for stem cell and transgenic mouse research

Authors: Marina V. Pryzhkova, Michelle J. Xu, Philip W. Jordan

Source: Stem Cell Research, Vol 49, Iss , Pp 102078- (2020)

Subject Terms: Auxin-inducible degron, Embryonic stem cells, SMC5/6 complex, H11 locus, CRISPR-Cas9, Transgenic mouse, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1873506120303792; https://doaj.org/toc/1873-5061

Access URL: https://doaj.org/article/842dc1005aef46c58b28b2e03adbcd2e

Auxin-Inducible Depletion of the Essentialome Suggests Inhibition of TORC1 by Auxins and Inhibition of Vrg4 by SDZ 90-215, a Natural Antifungal Cyclopeptide

Authors: Nathan A. Snyder, Adam Kim, Louis Kester, Andrew N. Gale, Christian Studer, Dominic Hoepfner, Silvio Roggo, Stephen B. Helliwell, Kyle W. Cunningham

Source: G3: Genes, Genomes, Genetics, Vol 9, Iss 3, Pp 829-840 (2019)

Subject Terms: auxin, auxin inducible degron, functional genomics, glycosylation, Golgi, rapamycin, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2160-1836

Access URL: https://doaj.org/article/3c656557bb5648078cf2ced79446adef

Condensin locates at transcriptional termination sites in mitosis, possibly releasing mitotic transcripts

Authors: Norihiko Nakazawa, Orie Arakawa, Mitsuhiro Yanagida

Source: Open Biology, Vol 9, Iss 10 (2019)

Subject Terms: condensin, chromosome segregation, fission yeast, mitosis, transcriptional termination, auxin-inducible degron, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-2441

Access URL: https://doaj.org/article/a2cbd90125b04f07836e4f57a2783975

Constructing Auxin-Inducible Degron Mutants Using an All-in-One Vector

Authors: Aisha Yesbolatova, Yuichiro Saito, Masato T. Kanemaki

Source: Pharmaceuticals, Vol 13, Iss 5, p 103 (2020)

Subject Terms: auxin-inducible degron, conditional protein depletion, gene knockout, expression vector, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/13/5/103; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/65718b3a72cb434d9ff7e7aa6a41d21a

Manipulating Histone H3 Methylation During Development: A Caenorhabditis Elegans Approach Toward Modeling Kabuki Syndrome.

Authors: Ortiz, Nathaniel

Contributors: Heiman, Maxwell, Morris, James

Source: Ortiz, Nathaniel. 2020. Manipulating Histone H3 Methylation During Development: A Caenorhabditis Elegans Approach Toward Modeling Kabuki Syndrome.. Master's thesis, Harvard Extension School.

Subject Terms: Kabuki syndrome, Caenorhabditis elegans, COMPASS/MLL, Histone, Auxin-inducible degron, histone-lysine N-methyltransferase 2D, histone-lysine demethylase 6A

File Description: application/pdf; application/pdf

Access URL: https://nrs.harvard.edu/URN-3:HUL.INSTREPOS:37365611

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