Compartmentalized role of xCT in supporting pancreatic tumor growth, inflammation and mood disturbance in mice

Authors: Lara, Olaya ^{a, b, 1}, Janssen, Pauline ^{a, b, 1}, Mambretti, Marco ^b, De Pauw, Laura ^a, Ates, Gamze ^a, Mackens, Liselotte ^a, De Munck, Jolien ^a, Walckiers, Jarne ^a, Pan, Zhaolong ^b, Beckers, Pauline ^c, Espinet, Elisa ^{d, e}, Sato, Hideyo ^f, De Ridder, Mark ^g, Marks, Daniel L. ^h, Barbé, Kurt ⁱ, Aerts, Joeri L. ^a, Hermans, Emmanuel ^c, Rooman, Ilse ^{b, 2, ⁎}, Massie, Ann ^{a, 2, ⁎}

Source: In Brain Behavior and Immunity May 2024 118:275-286

Neutral Red Uptake Assay to Assess Cytotoxicity In Vitro

Authors: Rodrigues, Robim M., Stinckens, Marth, Ates, Gamze, Vanhaecke, Tamara

Source: Methods in molecular biology. 2644:237-246

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632511370&indx=1&recIds=ETOCRN632511370

Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis

Authors: Van der Vreken, Arne, Oudaert, Inge, Ates, Gamze, Faict, Sylvia, Vlummens, Philip, Satilmis, Hatice, Fan, Rong, Maes, Anke, Massie, Ann, De Veirman, Kim, De Bruyne, Elke, Vanderkerken, Karin, Menu, Eline

Source: Journal of pathology. 260(2):112-123

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182493065.0x000001&indx=1&recIds=ETOCvdc_100182493065.0x000001

Targeting the β2‐adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism

Authors: Satilmis, Hatice, Verheye, Emma, Vlummens, Philip, Oudaert, Inge, Vandewalle, Niels, Fan, Rong, Knight, Jennifer M, De Beule, Nathan, Ates, Gamze, Massie, Ann, Moreaux, Jerome, Maes, Anke, De Bruyne, Elke, Vanderkerken, Karin, Menu, Eline, Sloan, Erica K, De Veirman, Kim

Source: Journal of pathology. 259(1):69-80

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100169507612.0x000001&indx=1&recIds=ETOCvdc_100169507612.0x000001

AMPKα1 Deficiency in Astrocytes from a Rat Model of ALS Is Associated with an Altered Metabolic Resilience.

Authors: Belo do Nascimento, Inês¹ (AUTHOR) ines.belo@uclouvain.be, Ates, Gamze² (AUTHOR) gamze.ates@vub.be, Desmet, Nathalie¹ (AUTHOR) nathalie.desmet@uclouvain.be, Beckers, Pauline¹ (AUTHOR) pauline.beckers@uclouvain.be, Massie, Ann² (AUTHOR) ann.massie@vub.be, Hermans, Emmanuel¹ (AUTHOR) emmanuel.hermans@uclouvain.be

Source: Biomolecules (2218-273X). Aug2023, Vol. 13 Issue 8, p1183. 16p.

Subject Terms: *AMYOTROPHIC lateral sclerosis, *GLUTAMATE transporters, *AMP-activated protein kinases, *ASTROCYTES, *ANIMAL disease models, *PROTEIN kinases

CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease

Authors: Ates, Gamze, Goldberg, Joshua, Currais, Antonio, Maher, Pamela

Source: In Redox Biology September 2020 36

(Q)SAR tools for priority setting: A case study with printed paper and board food contact material substances

Authors: Van Bossuyt, Melissa, Van Hoeck, Els, Raitano, Giuseppa, Manganelli, Serena, Braeken, Els, Ates, Gamze, Vanhaecke, Tamara, Van Miert, Sabine, Benfenati, Emilio, Mertens, Birgit, Rogiers, Vera

Source: In Food and Chemical Toxicology April 2017 102:109-119

CMS121 Partially Attenuates Disease Progression in Mouse Models of Huntington's Disease.

Authors: Ates, Gamze, Taguchi, Taketo, Maher, Pamela

Source: Molecular Neurobiology; Apr2024, Vol. 61 Issue 4, p2165-2175, 11p

Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq

Authors: Limonciel, Alice, Ates, Gamze, Carta, Giada, Wilmes, Anja, Watzele, Manfred, Shepard, Peter J., VanSteenhouse, Harper C., Seligmann, Bruce, Yeakley, Joanne M., van de Water, Bob, Vinken, Mathieu, Jennings, Paul

Source: Archives of toxicology. 92(8):2517-2531

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125620409.0x000001&indx=1&recIds=ETOCvdc_100125620409.0x000001

A novel genotoxin-specific qPCR array based on the metabolically competent human HepaRG™ cell line as a rapid and reliable tool for improved in vitro hazard assessment

Authors: Ates, Gamze, Mertens, Birgit, Heymans, Anja, Verschaeve, Luc, Milushev, Dimiter, Vanparys, Philippe, Roosens, Nancy H. C., De Keersmaecker, Sigrid C. J., Rogiers, Vera, Doktorova, Tatyana Y.

Source: Archives of toxicology. 92(4):1593-1608

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125621776.0x000001&indx=1&recIds=ETOCvdc_100125621776.0x000001

The Vitotox and ToxTracker assays: A two-test combination for quick and reliable assessment of genotoxic hazards

Authors: Ates, Gamze, Favyts, Dorien, Hendriks, Giel, Derr, Remco, Mertens, Birgit, Verschaeve, Luc, Rogiers, Vera, Y. Doktorova, Tatyana

Source: In Mutation Research - Genetic Toxicology and Environmental Mutagenesis 1 November 2016 810:13-21

Linking existing in vitro dermal absorption data to physicochemical properties: Contribution to the design of a weight-of-evidence approach for the safety evaluation of cosmetic ingredients with low dermal bioavailability

Authors: Ates, Gamze, Steinmetz, Fabian P., Doktorova, Tatyana Yordanova, Madden, Judith C., Rogiers, Vera

Source: In Regulatory Toxicology and Pharmacology April 2016 76:74-78

Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes

Authors: Chaudhari, Umesh, Nemade, Harshal, Sureshkumar, Poornima, Vinken, Mathieu, Ates, Gamze, Rogiers, Vera, Hescheler, Jürgen, Hengstler, Jan Georg, Sachinidis, Agapios

Source: Archives of toxicology. 92(1):371-381

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125189628.0x000001&indx=1&recIds=ETOCvdc_100125189628.0x000001

Assaying Cellular Viability Using the Neutral Red Uptake Assay

Authors: Ates, Gamze, Vanhaecke, Tamara, Rogiers, Vera, Rodrigues, Robim M.

Source: Methods in molecular biology. 1601:19-26

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN611403299&indx=1&recIds=ETOCRN611403299

Way forward in case of a false positive in vitro genotoxicity result for a cosmetic substance?

Authors: Doktorova, Tatyana Y., Ates, Gamze, Vinken, Mathieu, Vanhaecke, Tamara, Rogiers, Vera

Source: In Toxicology in Vitro February 2014 28(1):54-59

In vitro Dermal Absorption of Hydroquinone: Protocol Validation and Applicability on Illegal Skin-Whitening Cosmetics

Authors: Desmedt, Bart, Ates, Gamze, Courselle, Patricia, De Beer, Jacques O., Rogiers, Vera, Hendrickx, Benoit, Deconinck, Eric, De Paepe, Kristien

Source: Skin pharmacology and physiology. 29(6):300-308

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084813268.0x000001&indx=1&recIds=ETOCvdc_100084813268.0x000001

Targeting S100A9 protein affects mTOR-ER stress signaling and increases venetoclax sensitivity in Acute Myeloid Leukemia.

Authors: Fan, Rong, Satilmis, Hatice, Vandewalle, Niels, Verheye, Emma, De Bruyne, Elke, Menu, Eline, De Beule, Nathan, De Becker, Ann, Ates, Gamze, Massie, Ann, Kerre, Tessa, Törngren, Marie, Eriksson, Helena, Vanderkerken, Karin, Breckpot, Karine, Maes, Ken, De Veirman, Kim

Source: Blood Cancer Journal; 12/18/2023, Vol. 13 Issue 1, p1-12, 12p

Subject Terms: ACUTE myeloid leukemia, VENETOCLAX, DRUG target, ENDOPLASMIC reticulum, CELL survival, AZACITIDINE

Pancreatic acinar cell fate relies on system xC^- to prevent ferroptosis during stress.

Authors: Pan, Zhaolong, Van den Bossche, Jan-Lars, Rodriguez-Aznar, Eva, Janssen, Pauline, Lara, Olaya, Ates, Gamze, Massie, Ann, De Paep, Diedert Luc, Houbracken, Isabelle, Mambretti, Marco, Rooman, Ilse

Source: Cell Death & Disease; Aug2023, Vol. 14 Issue 8, p1-10, 10p

Effects of lactate, super-GDF9, and low oxygen tension during bi-phasic in vitro maturation on the bioenergetic profiles of mouse cumulus–oocyte complex†

Authors: Akin, Nazli, Ates, Gamze, von Mengden, Lucia, Herta, Anamaria-Cristina, Meriggioli, Cecilia, Billooye, Katy, Stocker, William A, Ghesquiere, Brecht, Harrison, Craig A, Cools, Wilfried, Klamt, Fabio, Massie, Ann, Smitz, Johan, Anckaert, Ellen

Source: Biology of Reproduction; October 2023, Vol. 109 Issue: 4 p432-449, 18p

Targeting the β2‐adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism.

Authors: Satilmis, Hatice, Verheye, Emma, Vlummens, Philip, Oudaert, Inge, Vandewalle, Niels, Fan, Rong, Knight, Jennifer M, De Beule, Nathan, Ates, Gamze, Massie, Ann, Moreaux, Jerome, Maes, Anke, De Bruyne, Elke, Vanderkerken, Karin, Menu, Eline, Sloan, Erica K, De Veirman, Kim

Source: Journal of Pathology; Jan2023, Vol. 259 Issue 1, p69-80, 12p

Subject Terms: MULTIPLE myeloma, CELL metabolism, CANCER cells, MONOCLONAL gammopathies, CARDIOVASCULAR agents, APOPTOSIS

Company/Entity: JOHN Wiley & Sons Inc.