Inhibition of cellular activation induced by platelet factor 4 via the CXCR3 pathway ameliorates Japanese encephalitis and dengue viral infections

Authors: Singh, Anamika, Ghosh, Riya, Asuru, Tejeswara Rao, Prajapat, Surendra K., Joshi, Garima, Gaur, Kishan K., Shrimali, Nishith M., Ojha, Amrita, Vikram, Naval K., Poncz, Mortimer, Kalia, Manjula, Guchhait, Prasenjit

Source: In Journal of Thrombosis and Haemostasis March 2024 22(3):818-833

7D, a small molecule inhibits dengue infection by increasing interferons and neutralizing-antibodies via CXCL4:CXCR3:p38:IRF3 and Sirt1:STAT3 axes respectively.

Authors: Gaur, Kishan Kumar, Asuru, Tejeswara Rao, Srivastava, Mitul, Singh, Nitu, Purushotham, Nikil, Poojary, Boja, Das, Bhabatosh, Bhattacharyya, Sankar, Asthana, Shailendra, Guchhait, Prasenjit

Source: EMBO Molecular Medicine; Oct2024, Vol. 16 Issue 10, p2376-2401, 26p

Dengue virus: pathogenesis and potential for small molecule inhibitors.

Authors: Chauhan, Navya, Gaur, Kishan Kumar, Asuru, Tejeswara Rao, Guchhait, Prasenjit

Source: Bioscience Reports; Aug2024, Vol. 44 Issue 8, p1-18, 18p

Subject Terms: SMALL molecules, VACCINE development, DRUG development, VACCINE effectiveness, ANTIVIRAL agents, DENGUE viruses

Dietary alpha‐ketoglutarate inhibits SARS CoV‐2 infection and rescues inflamed lungs to restore O2 saturation by inhibiting pAkt

Authors: Agarwal, Sakshi, Kaur, Simrandeep, Asuru, Tejeswara Rao, Joshi, Garima, Shrimali, Nishith M, Singh, Anamika, Singh, Oinam Ningthemmani, Srivastva, Puneet, Shrivastava, Tripti, Vrati, Sudhanshu, Surjit, Milan, Guchhait, Prasenjit

Source: Clinical and translational medicine. 12(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162418244.0x000001&indx=1&recIds=ETOCvdc_100162418244.0x000001

Dietary alpha‐ketoglutarate inhibits SARS CoV‐2 infection and rescues inflamed lungs to restore O2 saturation by inhibiting pAkt.

Authors: Agarwal, Sakshi, Kaur, Simrandeep, Asuru, Tejeswara Rao, Joshi, Garima, Shrimali, Nishith M, Singh, Anamika, Singh, Oinam Ningthemmani, Srivastva, Puneet, Shrivastava, Tripti, Vrati, Sudhanshu, Surjit, Milan, Guchhait, Prasenjit

Source: Clinical & Translational Medicine; Sep2022, Vol. 12 Issue 9, p1-6, 6p

Subject Terms: SARS-CoV-2, MUCUS, ANIMAL rescue, BLOOD platelet aggregation, LUNGS