Influenza virus infection enhances tumour-specific CD8+ T-cell immunity, facilitating tumour control.

Authors: Philine Steinbach, Eva Pastille, Lara Kaumanns, Alexandra Adamczyk, Kathrin Sutter, Wiebke Hansen, Ulf Dittmer, Jan Buer, Astrid M Westendorf, Torben Knuschke

Source: PLoS Pathogens, Vol 20, Iss 1, p e1011982 (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011982&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/a63e2a8e22f64398969f9161ce87c646

Neuropilin-1 identifies a subset of highly activated CD8+ T cells during parasitic and viral infections.

Authors: Hanna Abberger, Matthias Hose, Anne Ninnemann, Christopher Menne, Mareike Eilbrecht, Karl S Lang, Kai Matuschewski, Robert Geffers, Josephine Herz, Jan Buer, Astrid M Westendorf, Wiebke Hansen

Source: PLoS Pathogens, Vol 19, Iss 11, p e1011837 (2023)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/7b59caa70b0d472fb4113dc9f186b875

Cell-intrinsic ceramides determine T cell function during melanoma progression

Authors: Matthias Hose, Anne Günther, Eyad Naser, Fabian Schumacher, Tina Schönberger, Julia Falkenstein, Athanasios Papadamakis, Burkhard Kleuser, Katrin Anne Becker, Erich Gulbins, Adriana Haimovitz-Friedman, Jan Buer, Astrid M Westendorf, Wiebke Hansen

Source: eLife, Vol 11 (2022)

Subject Terms: sphingolipids, T cells, ceramide, melanoma, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/83073; https://doaj.org/toc/2050-084X

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The acid ceramidase/ceramide axis controls parasitemia in Plasmodium yoelii-infected mice by regulating erythropoiesis

Authors: Anne Günther, Matthias Hose, Hanna Abberger, Fabian Schumacher, Ylva Veith, Burkhard Kleuser, Kai Matuschewski, Karl Sebastian Lang, Erich Gulbins, Jan Buer, Astrid M Westendorf, Wiebke Hansen

Source: eLife, Vol 11 (2022)

Subject Terms: sphingolipids, ceramide, malaria, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/77975; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/d7bfdd0ec15f450d8112fb8ebc0a7fda

Immune hyporeactivity to bacteria and multiple TLR-ligands, yet no response to checkpoint inhibition in patients just after meeting Sepsis-3 criteria.

Authors: Alexandra Bick, Willem Buys, Andrea Engler, Rabea Madel, Mazen Atia, Francesca Faro, Astrid M Westendorf, Andreas Limmer, Jan Buer, Frank Herbstreit, Carsten J Kirschning, Jürgen Peters

Source: PLoS ONE, Vol 17, Iss 8, p e0273247 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6ea8ff6976ca474f997f552712c7e3fe

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.

Authors: Paul David, Malgorzata Drabczyk-Pluta, Eva Pastille, Torben Knuschke, Tanja Werner, Nadine Honke, Dominik A Megger, Ilseyar Akhmetzyanova, Namir Shaabani, Annette Eyking-Singer, Elke Cario, Olivia Kershaw, Achim D Gruber, Matthias Tenbusch, Kirsten K Dietze, Mirko Trilling, Jia Liu, Dirk Schadendorf, Hendrik Streeck, Karl S Lang, Youhua Xie, Lisa Zimmer, Barbara Sitek, Annette Paschen, Astrid M Westendorf, Ulf Dittmer, Gennadiy Zelinskyy

Source: PLoS Pathogens, Vol 16, Iss 3, p e1008340 (2020)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/9987cb67515b4dc9a412c66b03e91f68

Intestinal helminth infection drives carcinogenesis in colitis-associated colon cancer.

Authors: Eva Pastille, Annika Frede, Henry J McSorley, Jessica Gräb, Alexandra Adamczyk, Sebastian Kollenda, Wiebke Hansen, Matthias Epple, Jan Buer, Rick M Maizels, Robert Klopfleisch, Astrid M Westendorf

Source: PLoS Pathogens, Vol 13, Iss 9, p e1006649 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5627963?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

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Quantitative Comparison of Abundance Structures of Generalized Communities: From B-Cell Receptor Repertoires to Microbiomes.

Authors: Mohammadkarim Saeedghalati, Farnoush Farahpour, Bettina Budeus, Anja Lange, Astrid M Westendorf, Marc Seifert, Ralf Küppers, Daniel Hoffmann

Source: PLoS Computational Biology, Vol 13, Iss 1, p e1005362 (2017)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5293285?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/42bc802e27bd4c3f9f0543865469732c

Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota.

Authors: Bärbel Stecher, Riccardo Robbiani, Alan W Walker, Astrid M Westendorf, Manja Barthel, Marcus Kremer, Samuel Chaffron, Andrew J Macpherson, Jan Buer, Julian Parkhill, Gordon Dougan, Christian von Mering, Wolf-Dietrich Hardt

Source: PLoS Biology, Vol 5, Iss 10, Pp 2177-2189 (2007)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/afeccb6446b84bc3975aa7e3de0727f6

Hydrocortisone fails to abolish NF-κB1 protein nuclear translocation in deletion allele carriers of the NFKB1 promoter polymorphism (-94ins/delATTG) and is associated with increased 30-day mortality in septic shock.

Authors: Simon T Schäfer, Sophia Gessner, André Scherag, Katharina Rump, Ulrich H Frey, Winfried Siffert, Astrid M Westendorf, Jörg Steinmann, Jürgen Peters, Michael Adamzik

Source: PLoS ONE, Vol 9, Iss 8, p e104953 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4136840?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/7eab1cf054f94afc931c248e79a86408

Distinct kinetics in the frequency of peripheral CD4+ T cells in patients with ulcerative colitis experiencing a flare during treatment with mesalazine or with a herbal preparation of myrrh, chamomile, and coffee charcoal.

Authors: Jost Langhorst, Annika Frede, Markus Knott, Eva Pastille, Jan Buer, Gustav J Dobos, Astrid M Westendorf

Source: PLoS ONE, Vol 9, Iss 8, p e104257 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4140685?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e9e66ff665c34c2fa3dc592743d985d5

Local induction of immunosuppressive CD8+ T cells in the gut-associated lymphoid tissues.

Authors: Diana Fleissner, Wiebke Hansen, Robert Geffers, Jan Buer, Astrid M Westendorf

Source: PLoS ONE, Vol 5, Iss 10, p e15373 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2958146?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/119c584f57ef45138461e048d7b1df0d

Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity.

Authors: Sya N Ukena, Anurag Singh, Ulrike Dringenberg, Regina Engelhardt, Ursula Seidler, Wiebke Hansen, André Bleich, Dunja Bruder, Anke Franzke, Gerhard Rogler, Sebastian Suerbaum, Jan Buer, Florian Gunzer, Astrid M Westendorf

Source: PLoS ONE, Vol 2, Iss 12, p e1308 (2007)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/9d49b6f3f0d641289e56b96d8afc9204

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Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice

Authors: Christina Wenzek, Devon Siemes, G. Sebastian Hönes, Eva Pastille, Nina Härting, Frank Kaiser, Lars C. Moeller, Daniel R. Engel, Astrid M. Westendorf, Dagmar Führer

Source: iScience, Vol 27, Iss 8, Pp 110547- (2024)

Subject Terms: Molecular biology, Immunology, Endocrinology, Cell biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224017723; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/ccc41df7f60d483a819b4e87f9def24f

The ST2+ Treg/amphiregulin axis protects from immune-mediated hepatitis

Authors: Selina Wachtendorf, Fitriasari Jonin, Aaron Ochel, Fabian Heinrich, Astrid M. Westendorf, Gisa Tiegs, Katrin Neumann

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: Treg maintenance and function, ST2+ Tregs, ILC2s, amphiregulin, hepatic immunoregulation, liver inflammation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1351405/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/fa6213fcf2124cacb771a89ecf01098d

Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus

Authors: Vu Thuy Khanh Le-Trilling, Andreja Jagnjić, Ilija Brizić, Mareike Eilbrecht, Kerstin Wohlgemuth, Carmen Rožmanić, Alan Herdman, Katja Hoffmann, Astrid M. Westendorf, Hartmut Hengel, Stipan Jonjić, Mirko Trilling

Source: npj Vaccines, Vol 8, Iss 1, Pp 1-13 (2023)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2059-0105

Access URL: https://doaj.org/article/5bb5e1a25fb24a2880eaea087eec9796

CD47 blockade enhances phagocytosis of cardiac cell debris by neutrophils

Authors: Elias Haj-Yehia, Sebastian Korste, Robert Jochem, Aldona Lusha, Anna Roth, Nina Dietzel, Josefine Niroomand, Pia Stock, Astrid M. Westendorf, Jan Buer, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Totzeck

Source: International Journal of Cardiology: Heart & Vasculature, Vol 48, Iss , Pp 101269- (2023)

Subject Terms: CD47, Ischemia/reperfusion injury, Reperfused acute myocardial infarction, repAMI, Neutrophils, Phagocytosis, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352906723001008; https://doaj.org/toc/2352-9067

Access URL: https://doaj.org/article/3e38543a33e249afba3fe9903646b023