Efficacy of emergency maternal MVA-ZIKV vaccination in a rapid challenge model of lethal Zika infection

Authors: Asisa Volz, Sabrina Clever, Alina Tscherne, Astrid Freudenstein, Sylvia Jany, Jan H. Schwarz, Leonard Limpinsel, William G. Valiant, Georgia Kalodimou, Gerd Sutter, Joseph J. Mattapallil

Source: npj Vaccines, Vol 10, Iss 1, Pp 1-16 (2025)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2059-0105

Access URL: https://doaj.org/article/540359ecbdd6469c9e18e1f65bce5a9f

Rapid Development of Modified Vaccinia Virus Ankara (MVA)-Based Vaccine Candidates Against Marburg Virus Suitable for Clinical Use in Humans

Authors: Alina Tscherne, Georgia Kalodimou, Alexandra Kupke, Cornelius Rohde, Astrid Freudenstein, Sylvia Jany, Satendra Kumar, Gerd Sutter, Verena Krähling, Stephan Becker, Asisa Volz

Source: Vaccines, Vol 12, Iss 12, p 1316 (2024)

Subject Terms: Modified Vaccinia virus Ankara (MVA), viral vector vaccine, emerging viruses, rapid vaccine development, Marburg virus, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/12/1316; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/335b9ecf356444e18bbf4b531bcb86ea

Single MVA-SARS-2-ST/N Vaccination Rapidly Protects K18-hACE2 Mice against a Lethal SARS-CoV-2 Challenge Infection

Authors: Sabrina Clever, Leonard Limpinsel, Christian Meyer zu Natrup, Lisa-Marie Schünemann, Georg Beythien, Malgorzata Rosiak, Kirsten Hülskötter, Katharina Manuela Gregor, Tamara Tuchel, Georgia Kalodimou, Astrid Freudenstein, Satendra Kumar, Wolfgang Baumgärtner, Gerd Sutter, Alina Tscherne, Asisa Volz

Source: Viruses, Vol 16, Iss 3, p 417 (2024)

Subject Terms: SARS-CoV-2, poxvirus, multivalent vaccine, K18-hACE2 mice, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/3/417; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/dce965dac07f41e881175ae99326794b

Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity

Authors: Christian Meyer zu Natrup, Alina Tscherne, Christine Dahlke, Malgorzata Ciurkiewicz, Dai-Lun Shin, Anahita Fathi, Cornelius Rohde, Georgia Kalodimou, Sandro Halwe, Leonard Limpinsel, Jan H. Schwarz, Martha Klug, Meral Esen, Nicole Schneiderhan-Marra, Alex Dulovic, Alexandra Kupke, Katrin Brosinski, Sabrina Clever, Lisa-Marie Schünemann, Georg Beythien, Federico Armando, Leonie Mayer, Marie L. Weskamm, Sylvia Jany, Astrid Freudenstein, Tamara Tuchel, Wolfgang Baumgärtner, Peter Kremsner, Rolf Fendel, Marylyn M. Addo, Stephan Becker, Gerd Sutter, Asisa Volz

Source: The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)

Subject Terms: Infectious disease, Vaccines, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/c3dacfdcee5044c4a6d220158af4b33c

Newly Designed Poxviral Promoters to Improve Immunogenicity and Efficacy of MVA-NP Candidate Vaccines against Lethal Influenza Virus Infection in Mice

Authors: Martin C. Langenmayer, Anna-Theresa Luelf-Averhoff, Lisa Marr, Sylvia Jany, Astrid Freudenstein, Silvia Adam-Neumair, Alina Tscherne, Robert Fux, Juan J. Rojas, Andreas Blutke, Gerd Sutter, Asisa Volz

Source: Pathogens, Vol 12, Iss 7, p 867 (2023)

Subject Terms: influenza A virus, nucleoprotein, Modified Vaccinia virus Ankara, vaccine, synthetic VACV promoter, CD8+ T cell response, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/12/7/867; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/ed108fa0846b4fb79076124651caa712

Short- and Long-Interval Prime-Boost Vaccination with the Candidate Vaccines MVA-SARS-2-ST and MVA-SARS-2-S Induces Comparable Humoral and Cell-Mediated Immunity in Mice

Authors: Georgia Kalodimou, Sylvia Jany, Astrid Freudenstein, Jan Hendrik Schwarz, Leonard Limpinsel, Cornelius Rohde, Alexandra Kupke, Stephan Becker, Asisa Volz, Alina Tscherne, Gerd Sutter

Source: Viruses, Vol 15, Iss 5, p 1180 (2023)

Subject Terms: Modified Vaccinia virus Ankara, SARS-CoV-2, preclinical testing, vaccinia virus, vector vaccine, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/15/5/1180; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/1273b01d73fc4963ac4a077943276725

Protective CD8+ T Cell Response Induced by Modified Vaccinia Virus Ankara Delivering Ebola Virus Nucleoprotein

Authors: Alexandra Kupke, Asisa Volz, Erik Dietzel, Astrid Freudenstein, Jörg Schmidt, Hosam Shams-Eldin, Sylvia Jany, Lucie Sauerhering, Verena Krähling, Michelle Gellhorn Serra, Christiane Herden, Markus Eickmann, Stephan Becker, Gerd Sutter

Source: Vaccines, Vol 10, Iss 4, p 533 (2022)

Subject Terms: Ebola virus, Modified Vaccinia virus Ankara, vaccine, correlates of protection, nucleoprotein, glycoprotein, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/10/4/533; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/c197fefc32064d6e8959d5b89150555f

E3L and F1L Gene Functions Modulate the Protective Capacity of Modified Vaccinia Virus Ankara Immunization in Murine Model of Human Smallpox

Authors: Asisa Volz, Sylvia Jany, Astrid Freudenstein, Markus Lantermann, Holger Ludwig, Gerd Sutter

Source: Viruses, Vol 10, Iss 1, p 21 (2018)

Subject Terms: smallpox vaccination, MVA, immunogenic cell death, emergency vaccination, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.mdpi.com/1999-4915/10/1/21; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/3d42926771e947038926380bd2f119fd