Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

Authors: Harkness, Kirsty, Shaw, Louise, Sword, Jane, Mohd Nor, Azlisham, Sharma, Pankaj, Kelly, Deborah, Harrington, Frances, Randall, Marc, Smith, Matthew, Mahawish, Karim, Elmarim, Abduelbaset, Esisi, Bernard, Cullen, Claire, Nallasivam, Arumug, Price, Christopher, Barry, Adrian, Roffe, Christine, Coyle, John, Hassan, Ahamad, Birns, Jonathan, Cohen, David, Sekaran, Lakshmanan, Parry-Jones, Adrian, Parry, Anthea, Hargroves, David, Proschel, Harald, Datta, Prabel, Darawil, Khaled, Manoj, Aravindakshan, Burn, Mathew, Patterson, Chris, Giallombardo, Elio, Smyth, Nigel, Mansoor, Syed, Anwar, Ijaz, Marsh, Rachel, Ispoglou, Sissi, Chadha, Dinesh, Prabhakaran, Mathuri, Meenakishundaram, Sanjeevikumar, O'Connell, Janice, Scott, Jon, Krishnamurthy, Vinodh, Aghoram, Prasanna, McCormick, Michael, Sprigg, Nikola, O'Mahony, Paul, Cooper, Martin, Choy, Lillian, Wilkinson, Peter, Leach, Simon, Caine, Sarah, Burger, Ilse, Gunathilagan, Gunaratam, Guyler, Paul, Emsley, Hedley, Davis, Michelle, Manawadu, Dulka, Pasco, Kath, Mamun, Maam, Luder, Robert, Sajid, Mahmud, Okwera, James, Warburton, Elizabeth, Saastamoinen, Kari, England, Timothy, Putterill, Janet, Flossman, Enrico, Power, Michael, Dani, Krishna, Mangion, David, Suman, Appu, Corrigan, John, Lawrence, Enas, Vahidassr, Djamil, Shakeshaft, Clare, Brown, Martin, Charidimou, Andreas, Cohen, Hannah, Banerjee, Gargi, Houlden, Henry, White, Mark, Yousry, Tarek, Flossmann, Enrico, Muir, Keith, El-Koussy, Marwan, Gratz, Pascal, Molad, Jeremy, Korczyn, Amos, Kliper, Efrat, Maeder, Philippe, Gass, Achim, Pachai, Chahin, Bracoub, Luc, Douste-Blazy, Marie-Yvonne, Fratacci, Marie Dominique, Vicaut, Eric, Sato, Shoichiro, Miwa, Kaori, Fujita, Kyohei, Ide, Toshihiro, Ma, Henry, Ly, John, Singhal, Shahoo, Chandra, Ronil, Slater, Lee-Anne, Soufan, Cathy, Moran, Christopher, Traenka, Christopher, Thilemann, Sebastian, Fladt, Joachim, Gensicke, Henrik, Bonati, Leo, Kim, Beom Joon, Han, Moon-Ku, Kang, Jihoon, Ko, Eunbin, Yang, Mi Hwa, Jang, Myung Suk, Murphy, Sean, Carty, Fiona, Akijian, Layan, Thornton, John, Schembri, Mark, Douven, Elles, Delgado-Mederos;, Raquel, Marín, Rebeca, Camps-Renom, Pol, Guisado-Alonso, Daniel, Nuñez, Fidel, Medrano-Martorell, Santiago, Merino, Elisa, Iida, Kotaro, Ikeda, Syuhei, Nishihara, Masashi, Irie, Hiroyuki, Demirelli, Derya Selcuk, Medanta, Jayesh Modi, Zerna, Charlotte, Hernández, Maria Valdés, Armitage, Paul, Heye, Anna, Muñoz-Maniega, Susana, Sakka, Eleni, Thrippleton, Michael, Dennis, Martin, Beigneux, Ysoline, Silva, Mauro, Venketasubramanian, Narayanaswamy, Ho, Shu Leung, Cheung, Raymond Tak Fai, Chan, Koon Ho, Teo, Kay Cheong, Hui, Edward, Kwan, Joseph Shiu Kwong, Chang, Richard, Tse, Man Yu, Hoi, Chu Peng, Chan, Chung Yan, Chan, Oi Ling, Cheung, Ryan Hoi Kit, Wong, Edmund Ka Ming, Leung, Kam Tat, Tsang, Suk Fung, Ip, Hing Lung, Ma, Sze Ho, Ma, Karen, Fong, Wing Chi, Li, Siu Hung, Li, Richard, Ng, Ping Wing, Wong, Kwok Kui, Liu, Wenyan, Wong, Lawrence, Ramos, Lino, De Schryver, Els, Jöbsis, Joost, van der Sande, Jaap, Brouwers, Paul, Roos, Yvo, Stam, Jan, Bakker, Stef, Verbiest, Henk, Schoonewille, Wouter, Linn, Cisca, Hertzberger, Leopold, van Gemert, Maarten, Berntsen, Paul, Hendrikse, Jeroen, Nederkoorn, Paul, Mess, Werner, Koudstaal, Peter, Leff, Alexander, Ward, Nicholas, Nachev, Parashkev, Perry, Richard, Ozkan, Hatice, Mitchell, John, Wilson, Duncan, Ambler, Gareth, Lee, Keon-Joo, Lim, Jae-Sung, Shiozawa, Masayuki, Koga, Masatoshi, Li, Linxin, Lovelock, Caroline, Chabriat, Hugues, Hennerici, Michael, Wong, Yuen Kwun, Mak, Henry Ka Fung, Prats-Sánchez, Luis, Martínez-Domeño, Alejandro, Inamura, Shigeru, Yoshifuji, Kazuhisa, Arsava, Ethem Murat, Horstmann, Solveig, Purrucker, Jan, Lam, Bonnie Yin Ka, Wong, Adrian, Kim, Young Dae, Song, Tae-Jin, Schrooten, Maarten, Lemmens, Robin, Eppinger, Sebastian, Gattringer, Thomas, Uysal, Ender, Tanriverdi, Zeynep, Bornstein, Natan M, Assayag, Einor Ben, Hallevi, Hen, Tanaka, Jun, Hara, Hideo, Coutts, Shelagh B, Hert, Lisa, Polymeris, Alexandros, Seiffge, David J, Lyrer, Philippe, Algra, Ale, Kappelle, Jaap, Al-Shahi Salman, Rustam, Jäger, Hans R, Lip, Gregory Y H, Mattle, Heinrich P, Panos, Leonidas D, Mas, Jean-Louis, Legrand, Laurence, Karayiannis, Christopher, Phan, Thanh, Gunkel, Sarah, Christ, Nicolas, Abrigo, Jill, Leung, Thomas, Chu, Winnie, Chappell, Francesca, Makin, Stephen, Hayden, Derek, Williams, David J, Kooi, M Eline, van Dam-Nolen, Dianne H K, Barbato, Carmen, Browning, Simone, Wiegertjes, Kim, Tuladhar, Anil M, Maaijwee, Noortje, Guevarra, Christine, Yatawara, Chathuri, Mendyk, Anne-Marie, Delmaire, Christine, Köhler, Sebastian, van Oostenbrugge, Robert, Zhou, Ying, Xu, Chao, Hilal, Saima, Gyanwali, Bibek, Chen, Christopher, Lou, Min, Staals, Julie, Bordet, Régis, Kandiah, Nagaendran, de Leeuw, Frank-Erik, Simister, Robert, van der Lugt, Aad, Kelly, Peter J, Wardlaw, Joanna M, Soo, Yannie, Fluri, Felix, Srikanth, Velandai, Calvet, David, Jung, Simon, Kwa, Vincent I H, Engelter, Stefan T, Peters, Nils, Smith, Eric E, Yakushiji, Yusuke, Orken, Dilek Necioglu, Fazekas, Franz, Thijs, Vincent, Heo, Ji Hoe, Mok, Vincent, Veltkamp, Roland, Ay, Hakan, Imaizumi, Toshio, Gomez-Anson, Beatriz, Lau, Kui Kai, Jouvent, Eric, Rothwell, Peter M, Toyoda, Kazunori, Bae, Hee-Joon, Marti-Fabregas, Joan, Werring, David J ^*

Source: In The Lancet Neurology July 2019 18(7):653-665

Circle of Willis integrity in acute middle cerebral artery occlusion: does the posterior communicating artery matter?

Authors: Sadeh-Gonik, Udi, Budylev, Anatoly, Krivitzky, David, Molad, Jeremy, Halevi, Hen, Jonas-Kimchi, Tali, Yashar, Hila, Assayag, Einor Ben, Seyman, Estelle

Source: Journal of NeuroInterventional Surgery; Aug2024, Vol. 16 Issue 8, p801-808, 8p

Subject Terms: INTRACRANIAL aneurysm surgery, INTRACRANIAL aneurysms, CIRCLE of Willis, SURVIVAL rate, ANTERIOR cerebral artery, MULTIPLE regression analysis, BLOOD vessels, COMPUTED tomography, ENDOVASCULAR surgery, TREATMENT effectiveness, RETROSPECTIVE studies, DESCRIPTIVE statistics, MULTIVARIATE analysis, DECISION making in clinical medicine, CEREBRAL arteries, LONGITUDINAL method, STATISTICS, INFARCTION, THROMBECTOMY, STROKE, CONFIDENCE intervals, COLLATERAL circulation

Geographic Terms: ISRAEL

Blocking CCR5 activity by maraviroc augmentation in post-stroke depression: a proof-of-concept clinical trial.

Authors: Tene, Oren, Molad, Jeremy, Rotschild, Ofer, Alpernas, Aviva, Hawwari, Muhamad, Seyman, Estelle, Giladi, Nir, Hallevi, Hen, Assayag, Einor Ben

Source: BMC Neurology; 6/6/2024, Vol. 24 Issue 1, p1-9, 9p

Subject Terms: MENTAL depression, CHEMOKINE receptors, CLINICAL trials, PROOF of concept, STROKE

Early signaling of inflammation in acute ischemic stroke: Clinical and rheological implications

Authors: Shenhar-Tsarfaty, Shani, Assayag, Einor Ben, Bova, Irena, Shopin, Ludmila, Berliner, Shlomo, Shapira, Itzhak, Bornstein, Natan M.

Source: In Thrombosis Research 2008 122(2):167-173

Prognosis and Outcome of Cerebral Sinus Venous Thrombosis—A Multicenter Cohort Study.

Authors: Simaan, Naaem, Honig, Asaf, Hallevi, Hen, Seyman, Estelle, Rotschild, Ofer, Assayag, Einor Ben, Filioglo, Andrei, Peretz, Shlomi, Mendel, Rom, Barnea, Rani, Auriel, Eitan, Aladdin, Shorooq, Orion, David, Darawsha, Khalil, Shbat, Fadi, Leker, Ronen R., Molad, Jeremy

Source: Acta Neurologica Scandinavica; 2/7/2023, p1-7, 7p

Subject Terms: CRANIAL sinuses, SINUS thrombosis, VENOUS thrombosis, PROGNOSIS, ACADEMIC medical centers, INTRACEREBRAL hematoma

Preventing post-stroke dementia. The MARCH Trial. Protocol and statistical analysis plan of a randomized clinical trial testing the safety and efficacy of Maraviroc in post-stroke cognitive impairment.

Authors: Assayag, Einor Ben, Molad, Jeremy, Seyman, Estelle, Rotschild, Ofer, Zeltzer, Ehud, Sadeh-Gonik, Udi, Bregman, Noa, Alpernas, Aviva, Segal, Yahel, Bashat, Dafna Ben, Nathan, Talya, Hawwari, Muhamad, Tene, Oren, Hallevi, Hen

Source: European Stroke Journal; Sep2022, Vol. 7 Issue 3, p314-322, 9p

Inflammation-sensitive proteins and erythrocyte aggregation in atherothrombosis

Authors: Assayag, Einor Ben, Bornstein, Nathan, Shapira, Itzhak ^*, Mardi, Tamar, Goldin, Yelena, Tolshinski, Tatiana, Vered, Yafa, Zakuth, Vera, Burke, Michael, Berliner, Shlomo, Bonet, Dorit Samocha

Source: In International Journal of Cardiology 2005 98(2):271-276

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Genetic manipulations of CCR5 and the multifaceted molecular cellular and circuit mechanisms of cognitive enhancement: A cautionary tale

Authors: Silva, Alcino, Zhou, Miou, Shen, Yang, Joy, Mary T., Assayag, Einor Ben, Shabashov-Stone, Dalia, Silva, Tawnie, Kliper, Efrat, Liraz-Zaltsman, Sigal, Bornstein, Natan M., Shohami, Esther, Carmichael, Stanley T.

Source: In IBRO Reports September 2019 6 Supplement:S24-S24

The Price of Stress: High Bedtime Salivary Cortisol Levels Are Associated with Brain Atrophy and Cognitive Decline in Stroke Survivors. Results from the TABASCO Prospective Cohort Study.

Authors: Tene, Oren, Hallevi, Hen, Korczyn, Amos D., Shopin, Ludmila, Molad, Jeremy, Kirschbaum, Clemens, Bornstein, Natan M., Shenhar-Tsarfaty, Shani, Kliper, Efrat, Auriel, Eitan, Usher, Sali, Stalder, Tobias, Ben Assayag, Einor, Assayag, Einor Ben

Source: Journal of Alzheimer's Disease; 2018, Vol. 65 Issue 4, p1365-1375, 11p

Subject Terms: PSYCHOLOGICAL stress, HYDROCORTISONE, STROKE patients, CEREBRAL atrophy, BRAIN abnormalities, COGNITION disorders diagnosis, COGNITION disorder patients, MAGNETIC resonance imaging

Type 2 Diabetes Mellitus and Impaired Renal Function Are Associated With Brain Alterations and Poststroke Cognitive Decline.

Authors: Assayag, Einor Ben, Eldor, Roy, Korczyn, Amos D., Kliper, Efrat, Shenhar-Tsarfaty, Shani, Tene, Oren, Molad, Jeremy, Shapira, Itzhak, Berliner, Shlomo, Volfson, Viki, Shopin, Ludmila, Strauss, Yehuda, Hallevi, Hen, Bornstein, Natan M., Auriel, Eitan, Ben Assayag, Einor

Source: Stroke (00392499); Sep2017, Vol. 48 Issue 9, Following p2368-2374, 14p, 5 Charts, 3 Graphs

Only White Matter Hyperintensities Predicts Post-Stroke Cognitive Performances Among Cerebral Small Vessel Disease Markers: Results from the TABASCO Study.

Authors: Molad, Jeremy, Kliper, Efrat, Korczyn, Amos D., Assayag, Einor Ben, Bashat, Dafna Ben, Shenhar-Tsarfaty, Shani, Aizenstein, Orna, Shopin, Ludmila, Bornstein, Natan M., Auriel, Eitan, Ben Assayag, Einor, Ben Bashat, Dafna

Source: Journal of Alzheimer's Disease; 2017, Vol. 56 Issue 4, p1293-1299, 7p

Subject Terms: COGNITION disorders, TRANSIENT ischemic attack, CEREBRAL small vessel diseases, WHITE matter (Nerve tissue), PREDICTION models, COHORT analysis, BRAIN, CEREBRAL hemorrhage, CEREBRAL ischemia, CLINICAL trials, COGNITION, COMPARATIVE studies, LONGITUDINAL method, MAGNETIC resonance imaging, RESEARCH methodology, MEDICAL cooperation, PROGNOSIS, RESEARCH, EVALUATION research, STROKE, DISEASE complications, PSYCHOLOGY

Post-stroke dementia - a comprehensive review.

Authors: Mijajlović, Milija D., Pavlović, Aleksandra, Brainin, Michael, Heiss, Wolf-Dieter, Quinn, Terence J., Ihle-Hansen, Hege B., Hermann, Dirk M., Assayag, Einor Ben, Richard, Edo, Thiel, Alexander, Kliper, Efrat, Yong-Il Shin, Yun-Hee Kim, SeongHye Choi, San Jung, Yeong-Bae Lee, Sinanović, Osman, Levine, Deborah A., Schlesinger, Ilana, Mead, Gillian

Source: BMC Medicine; 1/18/2017, Vol. 15, p1-12, 12p, 2 Diagrams, 2 Charts

Subject Terms: TREATMENT of dementia, DEMENTIA patients, BRAIN imaging, GENETIC polymorphisms, IMAGING of cerebral circulation, COMPUTED tomography, MAGNETIC resonance imaging, POSITRON emission tomography, DIAGNOSIS of dementia, GERIATRIC assessment, DEMENTIA, PROGNOSIS, PSYCHOLOGICAL tests, QUESTIONNAIRES, STROKE, DISEASE complications

Impaired renal function is associated with brain atrophy and poststroke cognitive decline.

Authors: Auriel, Eitan, Kliper, Efrat, Shenhar-Tsarfaty, Shani, Molad, Jeremy, Berliner, Shlomo, Shapira, Itzhak, Ben-Bashat, Dafna, Shopin, Ludmila, Tene, Oren, Rosenberg, Gary A., Bornstein, Natan M., Assayag, Einor Ben, Ben Assayag, Einor

Source: Neurology; 5/24/2016, Vol. 86 Issue 21, p1996-2005, 10p

Depressive Symptoms Following Stroke and Transient Ischemic Attack: Is It Time for a More Intensive Treatment Approach? Results From the TABASCO Cohort Study.

Authors: Tene, Oren^1,2, Shenhar-Tsarfaty, Shani¹, Korczyn, Amos D.², Kliper, Efrat^1,2, Hallevi, Hen^1,2, Shopin, Ludmila¹, Auriel, Eitan¹, Mike, Anat¹, Bornstein, Natan M.^1,2 natanb@tlvmc.gov.il, Assayag, Einor Ben¹

Source: Journal of Clinical Psychiatry. May2016, Vol. 77 Issue 5, p673-680. 8p.

Gait Measures as Predictors of Poststroke Cognitive Function Evidence From the TABASCO Study.

Authors: Assayag, Einor Ben, Shenhar-Tsarfaty, Shani, Korczyn, Amos D., Kliper, Efrat, Hallevi, Hen, Shopin, Ludmila, Auriel, Eitan, Giladi, Nir, Mike, Anat, Halevy, Anat, Weiss, Aner, Mirelman, Anat, Bornstein, Natan M., Hausdorff, Jeffrey M.

Source: Stroke (00392499); Apr2015, Vol. 46 Issue 4, p1077-1083, 7p

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Cognitive decline after stroke: relation to inflammatory biomarkers and hippocampal volume.

Authors: Kliper, Efrat, Bashat, Dafna Ben, Bornstein, Natan M, Shenhar-Tsarfaty, Shani, Hallevi, Hen, Auriel, Eitan, Shopin, Ludmila, Bloch, Sivan, Berliner, Shlomo, Giladi, Nir, Goldbourt, Uri, Shapira, Itzhak, Korczyn, Amos D, Assayag, Einor Ben

Source: Stroke (00392499); May2013, Vol. 44 Issue 5, p1433-1435, 3p

The Butyrylcholinesterase K Variant Confers Structurally Derived Risks for Alzheimer Pathology.

Authors: PodoIy, Erez^1,2, ShaIev, Deborah E.², Shenhar-Tsarfaty, Shani³, Bennett, Estelle R.¹, Assayag, Einor Ben³, WiIgus, Harvey⁴, Livnah, Oded^1,2, Soreq, Hermona¹ soreq@cc.huji.ac.il

Source: Journal of Biological Chemistry. 6/19/2009, Vol. 284 Issue 25, p17170-17179. 10p. 7 Graphs.

Subject Terms: *BUTYRYLCHOLINESTERASE, *ALZHEIMER'S disease risk factors, *AMYLOID, *ACETYLCHOLINE, *NEUROBLASTOMA, *NEUROTOXICOLOGY, *PATHOLOGY