Two Novel Compounds Isolated from the Marine Fungal Symbiont of Aspergillus unguis Induce Apoptosis and Cell Cycle Arrest in Breast Cancer Cells: In vitro Study

Authors: Bashari MH, Agung MUK, Ariyanto EF, Al Muqarrabun LMR, Salsabila S, Chahyadi A, Rosandy AR, Afifah E, Afni M, Atmaja HE, Putri T, Utami F, Subhan B, Syafrizayanti, Andriani Y, Elfahmi

Source: Journal of Experimental Pharmacology, Vol Volume 17, Pp 37-50 (2025)

Subject Terms: aspergillus unguis, drug screening assays, porifera, triple negative breast neoplasms, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.dovepress.com/two-novel-compounds-isolated-from-the-marine-fungal-symbiont-of-asperg-peer-reviewed-fulltext-article-JEP; https://doaj.org/toc/1179-1454

Access URL: https://doaj.org/article/b530c1fc338a4abbab95fbaa5329aa1a

Anti-inflammatory potential of aspergillus unguis SP51-EGY: TLR4-dependent effects & chemical diversity via Q-TOF LC-HRMS

Authors: Soad Nasr, Abdelhameed S. Dawood, Amal Mosad Ibrahim, Mohamed S. Abdel-Aziz, Walid Fayad, Anwar Abdelnaser, Faten K. Abd EL-Hady

Source: BMC Biotechnology, Vol 24, Iss 1, Pp 1-21 (2024)

Subject Terms: Aspergillus unguis SP51-EGY, TLR4, Anti-inflammatory, Macrophages, Q-TOF LC-HRMS, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://doaj.org/toc/1472-6750

Access URL: https://doaj.org/article/7b27676a3773473faef88036e27c487e

Antimicrobial Natural Products

Contributors: Song, Fuhang, Feng, Yunjiang

Subject Terms: antimicrobials, Bacillus, probiotic, animal feed, omics, curcumin, metabolism, bioavailability, formulations, pharmacological activities, cyclic tetrapeptides, synergistic antifungal activity, molecular networking, Aspergillus westerdijkiae, marine-derived fungus, Talaromyces sp., antibacterial, Staphylococcus aureus, polyketide, Aspergillus terreus, Aspergillus unguis, co-culture, antimicrobial activity, LC-PDA-MS/MS, molecular network, database mining, plant metabolite, Bryophytes, moss, Physcomitrium patens, Sphagnum fallax, antibacterial activity, exudate, extract, bacitracin, cream, in vitro evaluation, chitosan, propolis, ethanol extracts, blends of propolis, phenolic compounds, antioxidant potential, Candida albicans, antagonistic microorganisms, biocontrol strategy, bioactive compounds, pestalachlorides, halogenase, genome-mining, flavin-dependent halogenases (FDHs), atropisomers, antimicrobial, antifungal, heteroaryl (aryl) thiazole derivatives, docking, Research and information: general, Chemistry

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/128711
https://mdpi.com/books/pdfview/book/8175

Marine Drug Research in China: Selected Papers from the 15-NASMD Conference

Contributors: Zhou, Xuefeng, Luo, Xiaowei, Liu, Yonghong

Subject Terms: Antarctic krill (Euphausia superba), peptide, antioxidant activity, stability, oyster, plasma, peptidome, antimicrobial peptides, cytotoxicity, actinomycete, piericidins, absolute configuration, Pestalotiopsis heterocornis, heterocornols, anti-inflammatory activity, sponge-derived fungus, sclerotides, lipodepsipeptide, Aspergillus sclerotiorum, nasopharyngeal carcinoma, AChE inhibitory, vascular endothelial cell, flavonoid, oxidized low-density lipoprotein, Nrf2, apoptosis, butyrolactone I, food allergy, metabolism, pharmacokinetics, actinomycin X2, microbial pigments, dyeing, silk, antibacterial properties, PD-L1, virtual screening, pharmacophore modeling, ADME, molecular dynamics, xanthones, ascidian-derived fungus, Diaporthe sp., anti-glioma activity, antiaging, Sonneratia apetala, signaling pathway, Caenorhabditis elegans, mutants, coral-derived fungi, Aspergillus hiratsukae, meroterpenoids, antibacterial activity, cytotoxic activity, deep-sea-derived fungus, Aspergillus puniceus, isoquinoline alkaloid, protein tyrosine phosphatase inhibitor, antibacterial, Aspergillus sp., geodin, semisynthesize, insecticidal activity, Arca inflata, antitumor peptide, MAPK signaling, calmodulin, colorectal cancer, methicillin-resistant Staphylococcus aureus, actinomycin D, Streptomyces parvulus, mechanism, mangrove endophytic Pestalotiopsis, Sdy-1, antitumor activity, Wnt signaling, β-catenin, eremophilane sesquiterpenoids, mangrove-derived fungus, Penicillium sp., Oceanapia, sponge, secondary metabolites, biological activities, drug design, anticancer, cyclic pentapeptide, galaxamide analogues, skipjack tuna (Katsuwonus pelamis) muscle, angiotensin-I-converting enzyme (ACE) peptide, molecular docking, nitric oxide (NO), endothelin-1 (ET-1), Trichoderma longibrachiatum, sesquiterpene glycoside, antimicrobial activity, marine fungi, Aspergillus unguis, depsides, depsidones, osteoclast differentiation, soft-coral-derived fungus, pyranodipyran derivatives, tyrosyl DNA phosphodiesterase 1 inhibitory activities, fluorescent properties, butenolides, enantiomers, Aspergillus terreus, pancreatic lipase, NAFLD, fucoxanthin, adenosine monophosphate-activated protein kinase (AMPK), nuclear factor erythroid-2-related factor 2-mediated (Nrf2), Toll-like receptor 4-mediated (TLR4), Aspergillus flavipes HN4-13, emodin, macroporous resin XAD-16, adsorption kinetics and isotherms, enrichment, tetramic acid derivatives, deep-sea fungus, clavipitacae, Lecanicillium fusisporum, chronic kidney disease, fucoidan, cognitive dysfunction, neuroinflammation, oxidative stress, GSK3β-Nrf2-HO-1 signaling, microglial polarization, deep-sea actinomycetes, aromatic acids, oximes, antihyperlipidemic, phycocyanin, microbiota, transcriptome, IL-17 pathway, Hahella, prodiginine, chejuenlide, genome mining, LC-MS/MS, CDK4/6, marine compounds, pharmacophore construction, ADMET, mm-pbsa, Medicine and Nursing

File Description: application/octet-stream

Access URL: https://directory.doabooks.org/handle/20.500.12854/92038
https://mdpi.com/books/pdfview/book/5911

Antiproliferative Role of Secondary Metabolites From Aspergillus unguis AG 1.1 (G) Isolated From Marine Macroalgae Enteromorpha sp. by Inducing Intracellular ROS Production and Mitochondrial Membrane Potential Loss Leading to Apoptosis

Authors: Kuttuvan Valappil Sajna, Siya Kamat, Chelliah Jayabaskaran

Source: Frontiers in Marine Science, Vol 7 (2020)

Subject Terms: secondary metabolites, anticancer, Aspergillus unguis, GC-MS, LC-MS/MS, endophytes, Science, General. Including nature conservation, geographical distribution, QH1-199.5

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmars.2020.543523/full; https://doaj.org/toc/2296-7745

Access URL: https://doaj.org/article/7e7edf93c7fb4090a47401ef8d3fd64d

Secondary Metabolite Variation and Bioactivities of Two Marine Aspergillus Strains in Static Co-Culture Investigated by Molecular Network Analysis and Multiple Database Mining Based on LC-PDA-MS/MS

Authors: Yuan Wang, Evgenia Glukhov, Yifan He, Yayue Liu, Longjian Zhou, Xiaoxiang Ma, Xueqiong Hu, Pengzhi Hong, William H. Gerwick, Yi Zhang

Source: Antibiotics, Vol 11, Iss 4, p 513 (2022)

Subject Terms: Aspergillus terreus, Aspergillus unguis, co-culture, antimicrobial activity, LC-PDA-MS/MS, molecular network, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/11/4/513; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/79efd48a5b5a40fd81603ad74b6dd55e

Anti-Osteoclastogenic and Antibacterial Effects of Chlorinated Polyketides from the Beibu Gulf Coral-Derived Fungus Aspergillus unguis GXIMD 02505

Authors: Yanting Zhang, Zhichao Li, Bingyao Huang, Kai Liu, Shuai Peng, Xinming Liu, Chenghai Gao, Yonghong Liu, Yanhui Tan, Xiaowei Luo

Source: Marine Drugs, Vol 20, Iss 3, p 178 (2022)

Subject Terms: marine fungi, Aspergillus unguis, depsides, depsidones, osteoclast differentiation, antibacterial, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1660-3397/20/3/178; https://doaj.org/toc/1660-3397

Access URL: https://doaj.org/article/e34b561ba6794712926f77a18769a53b

Antibacterial and Cytotoxic Phenolic Polyketides from Two Marine-Derived Fungal Strains of Aspergillus unguis

Authors: Cao Van Anh, Joo-Hee Kwon, Jong Soon Kang, Hwa-Sun Lee, Chang-Su Heo, Hee Jae Shin

Source: Pharmaceuticals, Vol 15, Iss 1, p 74 (2022)

Subject Terms: Aspergillus unguis, marine-derived fungus, phenolic polyketides, antibacterial, cytotoxicity, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/15/1/74; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/1705e94c1f5840dd917f8b41510506e7

Depsidone Derivatives and a Cyclopeptide Produced by Marine Fungus Aspergillus unguis under Chemical Induction and by Its Plasma Induced Mutant

Authors: Wen-Cong Yang, Hai-Yan Bao, Ya-Yue Liu, Ying-Ying Nie, Jing-Ming Yang, Peng-Zhi Hong, Yi Zhang

Source: Molecules, Vol 23, Iss 9, p 2245 (2018)

Subject Terms: depsidones, Aspergillus unguis, chemical induction, plasma-induced mutant, docking, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/23/9/2245; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/260a8b682057433bb9988fbdd4ea3ccd

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