NLRP3 deficiency abrogates silica-induced neutrophil infiltration, pulmonary damage and fibrosis

Authors: Maggie Lam, Kristian T. Barry, Christopher J. Hodges, Christopher M. Harpur, James D. H. Ong, Sarah Rosli, Alison C. West, Lovisa Dousha, Paul J. Hertzog, Ashley Mansell, Michelle D. Tate

Source: Respiratory Research, Vol 26, Iss 1, Pp 1-17 (2025)

Subject Terms: Silicosis, NLRP3 inflammasome, Mouse model, Inflammation, Fibrosis, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1465-993X

Access URL: https://doaj.org/article/43e7af70a23e4fc4969c7335cba14e91

NLRP1- A CINDERELLA STORY: a perspective of recent advances in NLRP1 and the questions they raise

Authors: Kristian Barry, Christopher Murphy, Ashley Mansell

Source: Communications Biology, Vol 6, Iss 1, Pp 1-7 (2023)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/5fbe5dea1c804a6abf8ecaef3abd03fc

Aggregated Hendra virus C-protein activates the NLRP3 inflammasome to induce inflammation

Authors: Kristian Barry, Christopher Harpur, Maggie Lam, Michelle D. Tate, Ashley Mansell

Source: Journal of Inflammation, Vol 20, Iss 1, Pp 1-12 (2023)

Subject Terms: Hendra, Virus, C-protein, NLRP3, Inflammasome, Inflammation, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1476-9255

Access URL: https://doaj.org/article/feaf3a4221284e8e960884093ed27a8f

Gasdermin D promotes hyperinflammation and immunopathology during severe influenza A virus infection

Authors: Sarah Rosli, Christopher M. Harpur, Maggie Lam, Alison C. West, Christopher Hodges, Ashley Mansell, Kate E. Lawlor, Michelle D. Tate

Source: Cell Death and Disease, Vol 14, Iss 11, Pp 1-11 (2023)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/9c7949fd85564d61aa791d0e32aed636

IL11 activates the placental inflammasome to drive preeclampsia

Authors: Ellen Menkhorst, Leilani L. Santos, Wei Zhou, Guannan Yang, Amy L. Winship, Katarzyna E. Rainczuk, Philana Nguyen, Jian-Guo Zhang, Paddy Moore, Michelle Williams, Kim-Anh Lê Cao, Ashley Mansell, Evdokia Dimitriadis

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: interleukin 11, preeclampsia, ASC, NLRP3, inflammasome, hypertension, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1175926/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/37e05e9c3dab4860b192b8a2938aaace

A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases

Authors: Callum AH Docherty, Anuruddika J Fernando, Sarah Rosli, Maggie Lam, Roland E Dolle, Manuel A Navia, Ronald Farquhar, Danny La France, Michelle D Tate, Christopher K Murphy, Adriano G Rossi, Ashley Mansell

Source: Clinical & Translational Immunology, Vol 12, Iss 6, Pp n/a-n/a (2023)

Subject Terms: drug targets, inflammasome, inflammation, NLRP1, NLRP3, pulmonary inflammation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0068

Access URL: https://doaj.org/article/f402fa42dc57419ea86338a42ffe4836

Evaluation of inflammation and follicle depletion during ovarian ageing in mice

Authors: Carolina Lliberos, Seng H. Liew, Pirooz Zareie, Nicole L. La Gruta, Ashley Mansell, Karla Hutt

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/ccf2ef3a52fb47d880669b6ed595328e

STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression

Authors: Jesse J. Balic, Hassan Albargy, Kevin Luu, Francis J. Kirby, W. Samantha N. Jayasekara, Finbar Mansell, Daniel J. Garama, Dominic De Nardo, Nikola Baschuk, Cynthia Louis, Fiachra Humphries, Katherine Fitzgerald, Eicke Latz, Daniel J. Gough, Ashley Mansell

Source: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/56d3ddfe137f4fb1a1f4f01e629a3c2e

The Inflammasome Contributes to Depletion of the Ovarian Reserve During Aging in Mice

Authors: Carolina Lliberos, Seng H. Liew, Ashley Mansell, Karla J. Hutt

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2021)

Subject Terms: inflammation, inflammasome, follicle, ovary, ovarian ageing, cytokine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2020.628473/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/2144ed2199814425ae78122c9886cfce

Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

Authors: Tali Lang, Jacinta P. W. Lee, Kirstin Elgass, Anita A. Pinar, Michelle D. Tate, Elizabeth H. Aitken, Huapeng Fan, Sarah J. Creed, Nadia S. Deen, Daouda A. K. Traore, Ivo Mueller, Danielle Stanisic, Francesca S. Baiwog, Colin Skene, Matthew C. J. Wilce, Ashley Mansell, Eric F. Morand, James Harris

Source: Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e3f4f9c8a1b94be9979682bf263d2d83

Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo

Authors: Jessica D. Cecil, Neil M. O’Brien-Simpson, Jason C. Lenzo, James A. Holden, William Singleton, Alexis Perez-Gonzalez, Ashley Mansell, Eric C. Reynolds

Source: Frontiers in Immunology, Vol 8 (2017)

Subject Terms: outer membrane vesicles, macrophages, inflammasomes, Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fimmu.2017.01017/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3fa2c660ae2843f8bb1a805d84bca6b2

Parsing the IL-37-Mediated Suppression of Inflammasome Function

Authors: Ina Rudloff, Holly K. Ung, Jennifer K. Dowling, Ashley Mansell, Laura D’Andrea, Andrew M. Ellisdon, James C. Whisstock, Philip J. Berger, Claudia A. Nold-Petry, Marcel F. Nold

Source: Cells, Vol 9, Iss 1, p 178 (2020)

Subject Terms: interleukin 37, interleukin 1β, interleukin 18, inflammasome, asc, caspase-1, pyroptosis, nlrp3, aim2, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/1/178; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/7071fae11d8d49f8bc767ea133c1627c

IRF7 in the Australian black flying fox, Pteropus alecto: evidence for a unique expression pattern and functional conservation.

Authors: Peng Zhou, Chris Cowled, Ashley Mansell, Paul Monaghan, Diane Green, Lijun Wu, Zhengli Shi, Lin-Fa Wang, Michelle L Baker

Source: PLoS ONE, Vol 9, Iss 8, p e103875 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4123912?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/13ce24245de647ae98f2a63fd1d1c9e2

MyD88 is a critical regulator of hematopoietic cell-mediated neuroprotection seen after stroke.

Authors: Catherine E Downes, Connie H Y Wong, Katya J Henley, Pedro L Guio-Aguilar, Moses Zhang, Robert Ates, Ashley Mansell, Benjamin T Kile, Peter J Crack

Source: PLoS ONE, Vol 8, Iss 3, p e57948 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23483951/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/aba7a1673b1c4d669cd0e9194af99a57

Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease.

Authors: Julie L McAuley, Michelle D Tate, Charley J MacKenzie-Kludas, Anita Pinar, Weiguang Zeng, Andrea Stutz, Eicke Latz, Lorena E Brown, Ashley Mansell

Source: PLoS Pathogens, Vol 9, Iss 5, p e1003392 (2013)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23737748/pdf/?tool=EBI; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/487231b4cf484a60809c34176b8b5705

An update on the NLRP3 inflammasome and influenza: the road to redemption or perdition?

Authors: Michelle D, Tate, Ashley, Mansell

Source: Current opinion in immunology. 54:80-85

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100069076704.0x000001&indx=1&recIds=ETOCvdc_100069076704.0x000001