Predicting COVID-19 booster immunogenicity against future SARS-CoV-2 variants and the benefits of vaccine updates

Authors: Deborah Cromer, Arnold Reynaldi, Ainslie Mitchell, Timothy E. Schlub, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, David S. Khoury, Miles P. Davenport

Source: Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2e91dd6127a5475a935ffe022d664285

Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis

Authors: Deborah Cromer, Megan Steain, Arnold Reynaldi, Timothy E. Schlub, Shanchita R. Khan, Sarah C. Sasson, Stephen J. Kent, David S. Khoury, Miles P. Davenport

Source: Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0ffd847cd5604f1bbad7250751912307

Preexisting immunity restricts mucosal antibody recognition of SARS-CoV-2 and Fc profiles during breakthrough infections

Authors: Kevin J. Selva, Pradhipa Ramanathan, Ebene R. Haycroft, Arnold Reynaldi, Deborah Cromer, Chee Wah Tan, Lin-Fa Wang, Bruce D. Wines, P. Mark Hogarth, Laura E. Downie, Samantha K. Davis, Ruth A. Purcell, Helen E. Kent, Jennifer A. Juno, Adam K. Wheatley, Miles P. Davenport, Stephen J. Kent, Amy W. Chung

Source: JCI Insight, Vol 8, Iss 18 (2023)

Subject Terms: COVID-19, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/5642c4f059134a179ab08b3553b928dd

Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations

Authors: Jennifer R. Habel, Brendon Y. Chua, Lukasz Kedzierski, Kevin J. Selva, Timon Damelang, Ebene R. Haycroft, Thi H.O. Nguyen, Hui-Fern Koay, Suellen Nicholson, Hayley A. McQuilten, Xiaoxiao Jia, Lilith F. Allen, Luca Hensen, Wuji Zhang, Carolien E. van de Sandt, Jessica A. Neil, Katherine Pragastis, Jillian S.Y. Lau, Jaycee Jumarang, E. Kaitlynn Allen, Fatima Amanant, Florian Krammer, Kathleen M. Wragg, Jennifer A. Juno, Adam K. Wheatley, Hyon-Xhi Tan, Gabrielle Pell, Susan Walker, Jennifer Audsley, Arnold Reynaldi, Irani Thevarajan, Justin T. Denholm, Kanta Subbarao, Miles P. Davenport, P. Mark Hogarth, Dale I. Godfrey, Allen C. Cheng, Steven Y.C. Tong, Katherine Bond, Deborah A. Williamson, James H. McMahon, Paul G. Thomas, Pia S. Pannaraj, Fiona James, Natasha E. Holmes, Olivia C. Smibert, Jason A. Trubiano, Claire L. Gordon, Amy W. Chung, Clare L. Whitehead, Stephen J. Kent, Martha Lappas, Louise C. Rowntree, Katherine Kedzierska

Source: JCI Insight, Vol 8, Iss 7 (2023)

Subject Terms: Immunology, Infectious disease, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/5baf2d86cad54efcaef6a7913823280a

Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19

Authors: Adam K. Wheatley, Jennifer A. Juno, Jing J. Wang, Kevin J. Selva, Arnold Reynaldi, Hyon-Xhi Tan, Wen Shi Lee, Kathleen M. Wragg, Hannah G. Kelly, Robyn Esterbauer, Samantha K. Davis, Helen E. Kent, Francesca L. Mordant, Timothy E. Schlub, David L. Gordon, David S. Khoury, Kanta Subbarao, Deborah Cromer, Tom P. Gordon, Amy W. Chung, Miles P. Davenport, Stephen J. Kent

Source: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e4e8f1c116754d5288a334fd4274b5ac

Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis

Authors: Deborah Cromer, PhD, Megan Steain, PhD, Arnold Reynaldi, PhD, Timothy E Schlub, PhD, Adam K Wheatley, PhD, Jennifer A Juno, PhD, Stephen J Kent, MD, James A Triccas, PhD, David S Khoury, PhD, Miles P Davenport, DPhil

Source: The Lancet Microbe, Vol 3, Iss 1, Pp e52-e61 (2022)

Subject Terms: Medicine (General), R5-920, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666524721002676; https://doaj.org/toc/2666-5247

Access URL: https://doaj.org/article/23977c96b0e84581a0a9625eb4ecfd5a

Anti-Drug Antibodies in Pigtailed Macaques Receiving HIV Broadly Neutralising Antibody PGT121

Authors: Wen Shi Lee, Arnold Reynaldi, Thakshila Amarasena, Miles P. Davenport, Matthew S. Parsons, Stephen J. Kent

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: HIV, broadly neutralizing antibodies (bNAb), PGT121, anti-drug antibodies (ADA), pigtailed macaque, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.749891/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/099d8252a5c742e2aa9272fa91e71d68

Decay of Fc-dependent antibody functions after mild to moderate COVID-19

Authors: Wen Shi Lee, Kevin John Selva, Samantha K. Davis, Bruce D. Wines, Arnold Reynaldi, Robyn Esterbauer, Hannah G. Kelly, Ebene R. Haycroft, Hyon-Xhi Tan, Jennifer A. Juno, Adam K. Wheatley, P. Mark Hogarth, Deborah Cromer, Miles P. Davenport, Amy W. Chung, Stephen J. Kent

Source: Cell Reports Medicine, Vol 2, Iss 6, Pp 100296- (2021)

Subject Terms: SARS-CoV-2, COVID-19, antibody, decay, Fc effector functions, ADCC, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666379121001294; https://doaj.org/toc/2666-3791

Access URL: https://doaj.org/article/055cad52624241e08920af0c14bd5a0d

Tear antibodies to SARS‐CoV‐2: implications for transmission

Authors: Kevin J Selva, Samantha K Davis, Ebene R Haycroft, Wen Shi Lee, Ester Lopez, Arnold Reynaldi, Miles P Davenport, Helen E Kent, Jennifer A Juno, Amy W Chung, Stephen J Kent

Source: Clinical & Translational Immunology, Vol 10, Iss 11, Pp n/a-n/a (2021)

Subject Terms: antibodies, COVID‐19, neutralisation, saliva, SARS‐CoV‐2, tears, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0068

Access URL: https://doaj.org/article/0dcabd136d5f4092a7816b36c8cabccb

Interaction between maternally derived antibodies and heterogeneity in exposure combined to determine time-to-first Plasmodium falciparum infection in Kenyan infants

Authors: Arnold Reynaldi, Arlene E. Dent, Timothy E. Schlub, Sidney Ogolla, Rosemary Rochford, Miles P. Davenport

Source: Malaria Journal, Vol 18, Iss 1, Pp 1-9 (2019)

Subject Terms: Plasmodium falciparum malaria, Antibody, Immunity, Heterogeneity in exposure, Newborns, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-019-2657-6; https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/139e27fbf6cf4d70981db0531bc0fa76

Exploration of broadly neutralizing antibody fragments produced in bacteria for the control of HIV

Authors: Sarah B. Lloyd, Keith P. Niven, Ben R. Kiefel, David C. Montefiori, Arnold Reynaldi, Miles P. Davenport, Stephen J. Kent, Wendy R. Winnall

Source: Human Vaccines & Immunotherapeutics, Vol 13, Iss 11, Pp 2726-2737 (2017)

Subject Terms: 10e8, broadly neutralizing antibodies, diabodies, e. coli expression, human immunodeficiency virus, pgt121, single-chain variable fragment antibodies, tandem-scfv, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/89a2356a613b4dbc9539b96d6c42d890

Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy.

Authors: Christine M Fennessey, Mykola Pinkevych, Taina T Immonen, Arnold Reynaldi, Vanessa Venturi, Priyanka Nadella, Carolyn Reid, Laura Newman, Leslie Lipkey, Kelli Oswald, William J Bosche, Matthew T Trivett, Claes Ohlen, David E Ott, Jacob D Estes, Gregory Q Del Prete, Jeffrey D Lifson, Miles P Davenport, Brandon F Keele

Source: PLoS Pathogens, Vol 13, Iss 5, p e1006359 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5433785?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/12624c7f2b5640c181fb68da867a31e1

Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys.

Authors: Alexandra M Ortiz, Diane G Carnathan, Joana Yu, Katherine M Sheehan, Peter Kim, Arnold Reynaldi, Thomas H Vanderford, Nichole R Klatt, Jason M Brenchley, Miles P Davenport, Guido Silvestri

Source: PLoS ONE, Vol 11, Iss 5, p e0156352 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4881966?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b3fd1c6b2328462cab246b510beb2726