Divergent effects of monomethyl branched-chain fatty acids on energy metabolism and insulin signaling in human myotubes

Authors: Parmeshwar Bajirao Katare, Ragna H. Tingstad, Sivar T. Beajani, Jørgen Pasjkurov Indseth, Vibeke H. Telle-Hansen, Mari C.W. Myhrstad, Arild C. Rustan, Lars Eide, Oliwia Witczak, Vigdis Aas

Source: Journal of Lipid Research, Vol 66, Iss 3, Pp 100764- (2025)

Subject Terms: energy homeostasis, obesity and metabolic diseases, skeletal muscle metabolism, dairy products, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227525000240; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/da9d8fb1d67544a99c6e5a8fac890861

Krill oil supplementation in vivo promotes increased fuel metabolism and protein synthesis in cultured human skeletal muscle cells

Authors: Parmeshwar B. Katare, Andrea Dalmao-Fernandez, Abel M. Mengeste, Farnaz Navabakbar, Håvard Hamarsland, Stian Ellefsen, Rolf K. Berge, Hege G. Bakke, Tuula Anneli Nyman, Eili Tranheim Kase, Arild C. Rustan, G. Hege Thoresen

Source: Frontiers in Nutrition, Vol 11 (2024)

Subject Terms: skeletal muscle cells, krill oil, energy metabolism, omega-3 fatty acids, mitochondria, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2024.1452768/full; https://doaj.org/toc/2296-861X

Access URL: https://doaj.org/article/9e7ce34d3fcf4ea690ea6faed4cb6cde

Human HDL subclasses modulate energy metabolism in skeletal muscle cells

Authors: Jenny Lund, Emilia Lähteenmäki, Tiia Eklund, Hege G. Bakke, G. Hege Thoresen, Eija Pirinen, Matti Jauhiainen, Arild C. Rustan, Maarit Lehti

Source: Journal of Lipid Research, Vol 65, Iss 1, Pp 100481- (2024)

Subject Terms: cellular respiration, substrate oxidation, glycolysis, oxidative phosphorylation, skeletal muscle myotubes, HDL subclasses, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227523001542; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/b2f1922a9f8b460c9bcc358cbd0235a3

Effect of noradrenaline on propofol-induced mitochondrial dysfunction in human skeletal muscle cells

Authors: Adéla Krajčová, Christine Skagen, Valér Džupa, Tomáš Urban, Arild C. Rustan, Kateřina Jiroutková, Bohumil Bakalář, G. Hege Thoresen, František Duška

Source: Intensive Care Medicine Experimental, Vol 10, Iss 1, Pp 1-14 (2022)

Subject Terms: Propofol infusion syndrome, Noradrenaline, Mitochondrial dysfunction, Skeletal muscle, Critical illness, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2197-425X

Access URL: https://doaj.org/article/b82e34584bbd453fa2f2d26a2cf87767

SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation

Authors: Solveig A. Krapf, Jenny Lund, Hege G. Bakke, Tuula A. Nyman, Stefano Bartesaghi, Xiao-Rong Peng, Arild C. Rustan, G. Hege Thoresen, Eili T. Kase

Source: Metabolism Open, Vol 18, Iss , Pp 100234- (2023)

Subject Terms: SENP2, Knockdown, Lentivirus, Primary human preadipocytes, Energy metabolism, Browning markers, Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589936823000063; https://doaj.org/toc/2589-9368

Access URL: https://doaj.org/article/ecf8c273e32343c2aa05e45db1565f81

Impairment of adrenergically-regulated thermogenesis in brown fat of obesity-resistant mice is compensated by non-shivering thermogenesis in skeletal muscle

Authors: Petra Janovska, Petr Zouhar, Kristina Bardova, Jakub Otahal, Marek Vrbacky, Tomas Mracek, Katerina Adamcova, Lucie Lenkova, Jiri Funda, Tomas Cajka, Zdenek Drahota, Sara Stanic, Arild C. Rustan, Olga Horakova, Josef Houstek, Martin Rossmeisl, Jan Kopecky

Source: Molecular Metabolism, Vol 69, Iss , Pp 101683- (2023)

Subject Terms: Non-shivering thermogenesis, Sarcolipin, Mitochondrial supercomplex, Skeletal muscle, Brown adipose tissue, Obesity, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877823000170; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/31f0b59f9117425794b61598c518ae9c

Development of three-dimensional primary human myospheres as culture model of skeletal muscle cells for metabolic studies

Authors: Andrea Dalmao-Fernandez, Aleksandra Aizenshtadt, Hege G. Bakke, Stefan Krauss, Arild C. Rustan, G. Hege Thoresen, Eili Tranheim Kase

Source: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)

Subject Terms: skeletal muscle, myosphere, energy metabolism, metabolic disorders, 3D cell model, muscle spheroid, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2023.1130693/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/b4dd0506ab1d4dd487b3cdad5fa28ab5

The effect of toll-like receptor ligands on energy metabolism and myokine expression and secretion in cultured human skeletal muscle cells

Authors: Ragna H. Tingstad, Frode Norheim, Fred Haugen, Yuan Z. Feng, Hege S. Tunsjø, G. Hege Thoresen, Arild C. Rustan, Colin Charnock, Vigdis Aas

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e35e695f03b54c55a8073c1741f89ab2

A medium-chain fatty acid analogue prevents hepatosteatosis and decreases inflammatory lipid metabolites in a murine model of parenteral nutrition-induced hepatosteatosis

Authors: Bennet S. Cho, Scott C. Fligor, Gillian L. Fell, Jordan D. Secor, Savas T. Tsikis, Amy Pan, Lumeng J. Yu, Victoria H. Ko, Duy T. Dao, Lorenzo Anez-Bustillos, Thomas I. Hirsch, Jenny Lund, Arild C. Rustan, David A. Fraser, Kathleen M. Gura, Mark Puder

Source: PLoS ONE, Vol 18, Iss 12 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10691711/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/28b3051b765841b4942b471325ef0c87

Editorial: Untangling energy metabolism in skeletal muscle: From physiology to pharmacology

Authors: Sergej Pirkmajer, Pablo M. Garcia-Roves, Arild C. Rustan, Alexander V. Chibalin

Source: Frontiers in Physiology, Vol 13 (2022)

Subject Terms: skeletal muscle, energy metabolism, AMPK, myosin, angiotensin-converting enzyme (ACE), metformin, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2022.1113860/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/9735c570ed7741699cf6a202bd10c6bd

Energy metabolism in skeletal muscle cells from donors with different body mass index

Authors: Parmeshwar B. Katare, Andrea Dalmao-Fernandez, Abel M. Mengeste, Håvard Hamarsland, Stian Ellefsen, Hege G. Bakke, Eili Tranheim Kase, G. Hege Thoresen, Arild C. Rustan

Source: Frontiers in Physiology, Vol 13 (2022)

Subject Terms: skeletal muscle cells, eicosapentaenoic acid, EPA, metabolism, obesity, mitochondria, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2022.982842/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/9e8ef44ccc444d4ea2ea123cc1162d40

Interplay between Cultured Human Osteoblastic and Skeletal Muscle Cells: Effects of Conditioned Media on Glucose and Fatty Acid Metabolism

Authors: Ngoc Nguyen Lunde, Nimo Mukhtar Mohamud Osoble, Andrea Dalmao Fernandez, Alfreda S. Antobreh, Abbas Jafari, Sachin Singh, Tuula A. Nyman, Arild C. Rustan, Rigmor Solberg, G. Hege Thoresen

Source: Biomedicines, Vol 11, Iss 11, p 2908 (2023)

Subject Terms: energy metabolism, myokines, osteoblastic cells, osteokines, primary human myotubes, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/11/11/2908; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/9b55cb3472654e90987d9dbb647f0ff7

Insight Into the Metabolic Adaptations of Electrically Pulse-Stimulated Human Myotubes Using Global Analysis of the Transcriptome and Proteome

Authors: Abel M. Mengeste, Nataša Nikolić, Andrea Dalmao Fernandez, Yuan Z. Feng, Tuula A. Nyman, Sander Kersten, Fred Haugen, Eili Tranheim Kase, Vigdis Aas, Arild C. Rustan, G. Hege Thoresen

Source: Frontiers in Physiology, Vol 13 (2022)

Subject Terms: exercise, skeletal muscle, energy metabolism, myokines, omics, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2022.928195/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/9dba3ff975f94e63b19ff885e811c46a

Pancreatic Cancer Cell-Conditioned, Human-Derived Primary Myotubes Display Increased Leucine Turnover, Increased Lipid Accumulation, and Reduced Glucose Uptake

Authors: Solveig A. Krapf, Jenny Lund, Awais Ur Rehman Saqib, Hege G. Bakke, Arild C. Rustan, G. Hege Thoresen, Eili T. Kase

Source: Metabolites, Vol 12, Iss 11, p 1095 (2022)

Subject Terms: cachexia, cross talk, energy metabolism, protein metabolism, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-1989/12/11/1095; https://doaj.org/toc/2218-1989

Access URL: https://doaj.org/article/867b467274c849e1b425b83c27fe4b26

The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells

Authors: Abel M. Mengeste, Jenny Lund, Parmeshwar Katare, Roya Ghobadi, Hege G. Bakke, Per Kristian Lunde, Lars Eide, Gavin O’ Mahony, Sven Göpel, Xiao-Rong Peng, Eili Tranheim Kase, G. Hege Thoresen, Arild C. Rustan

Source: Current Research in Pharmacology and Drug Discovery, Vol 2, Iss , Pp 100060- (2021)

Subject Terms: Obesity, Type 2 diabetes, Skeletal muscle, SERCA, Glucose metabolism, Lipid metabolism, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S259025712100047X; https://doaj.org/toc/2590-2571

Access URL: https://doaj.org/article/ca2e8dd4b3ef4e27af96a4d4cc90fef0

SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells

Authors: Jenny Lund, Solveig A. Krapf, Medina Sistek, Hege G. Bakke, Stefano Bartesaghi, Xiao-Rong Peng, Arild C. Rustan, G. Hege Thoresen, Eili T. Kase

Source: Current Research in Pharmacology and Drug Discovery, Vol 2, Iss , Pp 100061- (2021)

Subject Terms: SENP2, Lentivirus, Knockdown, Primary human myotubes, Energy metabolism, Insulin sensitivity, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590257121000481; https://doaj.org/toc/2590-2571

Access URL: https://doaj.org/article/1aefb167ef6a43069d7e66d63da000b8

Loss of lysosomal membrane protein NCU-G1 in mice results in spontaneous liver fibrosis with accumulation of lipofuscin and iron in Kupffer cells

Authors: Xiang Y. Kong, Cecilie Kasi Nesset, Markus Damme, Else-Marit Løberg, Torben Lübke, Jan Mæhlen, Kristin B. Andersson, Petra I. Lorenzo, Norbert Roos, G. Hege Thoresen, Arild C. Rustan, Eili T. Kase, Winnie Eskild

Source: Disease Models & Mechanisms, Vol 7, Iss 3, Pp 351-362 (2014)

Subject Terms: NCU-G1, Lysosome, Fibrosis, Medicine, Pathology, RB1-214

File Description: electronic resource

Relation: http://dmm.biologists.org/content/7/3/351; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

Access URL: https://doaj.org/article/118cd37476824946b0852ead9ad9bb7b

Regulation of skeletal muscle lipolysis and oxidative metabolism by the co-lipase CGI-58

Authors: Pierre-Marie Badin, Camille Loubière, Maarten Coonen, Katie Louche, Geneviève Tavernier, Virginie Bourlier, Aline Mairal, Arild C. Rustan, Steven R. Smith, Dominique Langin, Cedric Moro

Source: Journal of Lipid Research, Vol 53, Iss 5, Pp 839-848 (2012)

Subject Terms: comparative gene identification 58, fatty acid, substrate oxidation, intramyocellular triacylglycerol, peroxisome proliferator-activated receptor, mitochondria, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520392142; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/259e8894db5b4c6d80ad2009c04bcb9b

Eicosapentaenoic acid (20:5 n-3) increases fatty acid and glucose uptake in cultured human skeletal muscle cells

Authors: Vigdis Aas, Merethe H. Rokling-Andersen, Eili Tranheim Kase, G. Hege Thoresen, Arild C. Rustan

Source: Journal of Lipid Research, Vol 47, Iss 2, Pp 366-374 (2006)

Subject Terms: human skeletal myotubes, lipid metabolism, glucose metabolism, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520336373; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/cffeba37fb004c2ab81fa799a17de1d7

Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases

Authors: Rasmus K. Petersen, Claus J⊘rgensen, Arild C. Rustan, Livar Fr⊘yland, Karin Muller-Decker, Gerhard Furstenberger, Rolf K. Berge, Karsten Kristiansen, Lise Madsen

Source: Journal of Lipid Research, Vol 44, Iss 12, Pp 2320-2330 (2003)

Subject Terms: mitogen-activated protein kinase, peroxisome proliferator-activated receptor, CCAAT/enhancer-binding protein, diacylglycerol acyltransferase, protein kinase A, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520319507; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/a8de303a3ce240de8b9bab9921bfef81