An SLC12A9-dependent ion transport mechanism maintains lysosomal osmolarity

Authors: Levin-Konigsberg, Roni ¹, Mitra, Koushambi ^{2, 3, 4, 11}, Spees, Kaitlyn ^{1, 11}, Nigam, AkshatKumar ^{5, 11}, Liu, Katherine ⁶, Januel, Camille ⁷, Hivare, Pravin ³, Arana, Sophia M. ¹, Prolo, Laura M. ⁸, Kundaje, Anshul ^{1, 5}, Leonetti, Manuel D. ⁷, Krishnan, Yamuna ^{2, 3, 4}, Bassik, Michael C. ^{1, 9, 10, 12, ∗}

Source: In Developmental Cell 20 January 2025 60(2):220-235

Review: therapeutic approaches for circadian modulation of the glioma microenvironment.

Authors: Nettnin, Ella A., Nguyen, Thien, Arana, Sophia, Guinle, Maria Isabel Barros, Garcia, Cesar A., Gibson, Erin M., Prolo, Laura M.

Source: Frontiers in Oncology; 2024, p1-13, 13p

Subject Terms: BRAIN tumors, THERAPEUTICS, GLIOMAS, CHIMERIC antigen receptors, CHILD patients, TUMOR microenvironment

CDC42BPA::BRAF represents a novel fusion in desmoplastic infantile ganglioglioma/desmoplastic infantile astrocytoma.

Authors: Barros Guinle, Maria Isabel, Nirschl, Jeffrey J, Xing, Yao Lulu, Nettnin, Ella A, Arana, Sophia, Feng, Zhi-Ping, Nasajpour, Emon, Pronina, Anna, Garcia, Cesar A, Grant, Gerald A, Vogel, Hannes, Yeom, Kristen W, Prolo, Laura M, Petritsch, Claudia K

Source: Neuro-Oncology Advances; Jan-Dec2024, Vol. 6 Issue 1, p1-7, 7p

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts.

Authors: Tycko, Josh^1,2 (AUTHOR), Van, Mike V. (AUTHOR), Aradhana (AUTHOR), DelRosso, Nicole (AUTHOR), Ye, Hanrong (AUTHOR), Yao, David (AUTHOR), Valbuena, Raeline (AUTHOR), Vaughan-Jackson, Alun^1,3 (AUTHOR), Xu, Xiaoshu (AUTHOR), Ludwig, Connor (AUTHOR), Spees, Kaitlyn (AUTHOR), Liu, Katherine (AUTHOR), Gu, Mingxin (AUTHOR), Khare, Venya (AUTHOR), Mukund, Adi Xiyal (AUTHOR), Suzuki, Peter H. (AUTHOR), Arana, Sophia (AUTHOR), Zhang, Catherine (AUTHOR), Du, Peter P. (AUTHOR), Ornstein, Thea S. (AUTHOR)

Source: Nature Biotechnology. Nov2024, p1-14.

Subject Terms: *CHIMERIC antigen receptors, *NUCLEAR proteins, *PROTEIN domains, *TRANSCRIPTION factors, *IMMUNE response