Genomic and transcriptomic correlates of Richter transformation in chronic lymphocytic leukemia

Authors: Klintman, Jenny ^*, Appleby, Niamh ^*, Stamatopoulos, Basile, Ridout, Katie, Eyre, Toby A., Robbe, Pauline, Pascua, Laura Lopez, Knight, Samantha J.L., Dreau, Helene, Cabes, Maite, Popitsch, Niko, Ehinger, Mats, Martín-Subero, Jose I., Campo, Elías, Månsson, Robert, Rossi, Davide, Taylor, Jenny C., Vavoulis, Dimitrios V., Schuh, Anna ^**

Source: In Blood 20 May 2021 137(20):2800-2816

Measuring Health-Related Quality of Life in Amyotrophic Lateral Sclerosis: A Systematic Review and Conceptual Framework.

Authors: McDool, Emily, Carlton, Jill, Powell, Philip A., Coates, Elizabeth, Knox, Liam, Mayberry, Emily, Appleby, Niamh, Griffiths, Alys W., Hobson, Esther, McDermott, Christopher J.

Source: Neurology; 7/23/2024, Vol. 103 Issue 2, p1-10, 10p

The STELLAR trial protocol: a prospective multicentre trial for Richter's syndrome consisting of a randomised trial investigation CHOP-R with or without acalabrutinib for newly diagnosed RS and a single-arm platform study for evaluation of novel agents in relapsed disease

Authors: Appleby, Niamh, Eyre, Toby, Cabes, Maite, Jackson, Aimee, Boucher, Rebecca, Yates, Francesca, Fox, Sonia, Rawstron, Andrew, Hillmen, Peter, Schuh, Anna

Source: BMC cancer. 19(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188042081.0x000001&indx=1&recIds=ETOCvdc_100188042081.0x000001

Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib

Authors: Bye, Alexander P., Unsworth, Amanda J., Desborough, Michael J., Hildyard, Catherine A.T., Appleby, Niamh, Bruce, David, Kriek, Neline, Nock, Sophie H., Sage, Tanya, Hughes, Craig E. ^*, Gibbins, Jonathan M. ^*

Source: In Blood Advances 12 December 2017 1(26):2610-2623

Risk adjusted therapy in chronic lymphocytic leukemia: a phase II cancer trials Ireland (CTRIAL-IE [ICORG 07-01]) study of fludarabine, cyclophosphamide, and rituximab therapy evaluating response adapted, abbreviated frontline therapy with FCR in non-del(17p) CLL

Authors: Appleby, Niamh, O'Brien, David, Quinn, Fiona M., Smyth, Liam, Kelly, Johanna, Parker, Imelda, Scott, Kathleen, Cahill, Mary R., Crotty, Gerard, Enright, Helen, Hennessy, Brian, Hodgson, Andrew, Leahy, Maeve, O'Leary, Hilary, O'Dwyer, Michael, Hayat, Amjad, Vandenberghe, Elisabeth A.

Source: Leukemia & lymphoma. 59(6):1338-1347

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100062577649.0x000001&indx=1&recIds=ETOCvdc_100062577649.0x000001

Whole Genome Classification of Pre-Malignant B-Cells Disorder of the Oxplored Study

Authors: Robbe, Pauline, Ridout, Kate, Appleby, Niamh, Ciuban, Georgeta, Batth, Gagandeep, Dreau, Helene, Wenban-Smith, Thomas, Kormandy, Melinda, Gafencu, Grigore-Aristide, Carninci, Piero, Freestone, Clare, McAleese, Daniel, Vavoulis, Dimitrios, Schuh, Anna

Source: In Blood 2 November 2023 142 Supplement 1:3256-3256

Cellular Therapy in High-Risk Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter Syndrome.

Authors: Barbanti, Maria Chiara, Appleby, Niamh, Kesavan, Murali, Eyre, Toby Andrew

Source: Frontiers in Oncology; 4/28/2022, Vol. 12, p1-9, 9p

Subject Terms: RICHTER syndrome, CHRONIC lymphocytic leukemia, LYMPHOCYTOSIS, CELLULAR therapy, CD19 antigen, STEM cell transplantation, HISTOCOMPATIBILITY antigens

Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features

Authors: Robbe, Pauline, Ridout, Kate E., Vavoulis, Dimitrios V., Dréau, Helene, Kinnersley, Ben, Denny, Nicholas, Chubb, Daniel, Appleby, Niamh, Cutts, Anthony, Cornish, Alex J., Lopez-Pascua, Laura, Clifford, Ruth, Burns, Adam, Stamatopoulos, Basile, Cabes, Maite, Alsolami, Reem, Antoniou, Pavlos, Oates, Melanie, Cavalieri, Doriane, Gibson, Jane, Prabhu, Anika V., Schwessinger, Ron, Jennings, Daisy, James, Terena, Maheswari, Uma, Duran-Ferrer, Martí, Carninci, Piero, Knight, Samantha J. L., Månsson, Robert, Hughes, Jim, Davies, James, Ross, Mark, Bentley, David, Strefford, Jonathan C., Devereux, Stephen, Pettitt, Andrew R., Hillmen, Peter, Caulfield, Mark J., Houlston, Richard S., Martín-Subero, José I., Schuh, Anna

Source: Nature Genetics; November 2022, Vol. 54 Issue: 11 p1675-1689, 15p

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Symptomatic BK virus reactivation following fludarabine, cyclophosphamide and rituximab chemotherapy for chronic lymphocytic leukemia/small lymphocytic lymphoma.

Authors: Appleby, Niamh¹ (AUTHOR) applebyn@gmail.com, Dillon, Anna¹ (AUTHOR), Arrigan, Martin² (AUTHOR), Fennell, Jerome³ (AUTHOR), Crowley, Brendan¹ (AUTHOR), Hayden, Patrick J.¹ (AUTHOR), Enright, Helen¹ (AUTHOR)

Source: Leukemia & Lymphoma. May2014, Vol. 55 Issue 5, p1181-1183. 3p.

Subject Terms: *BK virus diseases, *VIRUS diseases, *POLYOMAVIRUSES, *LYMPHOMA treatment, *DRUG side effects, *THERAPEUTICS

Highly Comprehensive Genomic Testing for CLL: WGS, One Key to CLL Patient Stratification

Authors: Ridout, Kate E ^*, Robbe, Pauline ^*, Cavalieri, Doriane ^*, Becq, Jennifer ^*, He, Miao ^*, Clifford, Ruth ^*, Appleby, Niamh ^*, Alsolami, Reem ^*, Burns, Adam ^*, Oates, Melanie ^*, Stamatopoulos, Basile ^*, Knight, Samantha ^*, Sosinsky, Alona ^*, Antoniou, Pavlos ^*, Ross, Mark ^*, Bentley, David ^*, Pettitt, Andrew ^*, Hillmen, Peter, Caulfield, Mark ^*, Schuh, Anna

Source: In Blood 29 November 2018 132 Supplement 1:3115-3115

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Minimal Residual Disease (MRD) Status in FCR-Treated CLL Patients at the End of Treatment Influences Progression Free Survival (PFS), Results of the Ctrial-IE (ICORG) 07-01/ CLL Ireland Study, with Mutational Analysis Providing Additional Insight

Authors: Appleby, Niamh ^*, Quinn, Fiona M ^*, O'Brien, David ^*, Liam, Smyth ^*, Kelly, Johanna ^*, Parker, Imelda ^*, Scott, Kathleen ^*, Cahill, Mary R ^*, Crotty, Gerard ^*, Enright, Helen ^*, Hennessy, Brian ^*, Hodgson, Andrew, Leahy, Maeve ^*, O'Leary, Hilary M ^*, O'Dwyer, Michael E, Hayat, Amjad, Vandenberghe, Elisabeth A.

Source: In Blood 2 December 2016 128(22):3237-3237

Poor Outcomes in HIV Negative and HIV Positive Patients with Plasmablastic Lymphoma (PBL) in a Population Based Patient Study

Authors: Appleby, Niamh ^*, Cullen, Ruth ^*, Painter, Dan ^*, Smith, Alexandra ^*, Roman, Eve ^*, Barrans, Sharon ^*, O'Connor, Sheila J.M. ^*, Burton, Catherine H ^*, Jack, Andrew S, Owen, Roger G, Tooze, Reuben M

Source: In Blood 3 December 2015 126(23):3924-3924

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