Contemporary trends and outcomes after liver transplantation and resection for intrahepatic cholangiocarcinoma

Authors: Howell, Thomas Clark, Rhodin, Kristen E., Shaw, Brian, Bao, Jiayin, Kanu, Elishama, Masoud, Sabran, Bartholomew, Alex J., Gao, Qimeng, Anwar, Imran J., Ladowski, Joseph M., Nussbaum, Daniel P., Blazer, Dan G., 3rd, Zani, Sabino, Allen, Peter J., Barbas, Andrew S., Lidsky, Michael E.

Source: In Journal of Gastrointestinal Surgery May 2024 28(5):738-745

Incidence of Postreperfusion Hyperfibrinolysis in Liver Transplantation by Donor Type and Observed Treatment Strategies

Authors: Krom, Russell J., Welsby, Ian J., Fuller, Matthew, Barbas, Andrew S., Gao, Qimeng, Anwar, Imran J., Dunkman, W. Jonathan

Source: Anesthesia & analgesia. 136(3):518-523

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Revisiting Medical Student Expectations on the Surgery Clerkship

Authors: Rhodin, Kristen E., Leraas, Harold, Nash, Amanda L., Gao, Qimeng, Anwar, Imran J, Kang, Lillian, Ladowski, Joseph M, Tracy, Elisabeth, Migaly, John, Vatsaas, Cory J

Source: In Journal of Surgical Education October 2023 80(10):1358-1361

Xenorecognition and costimulation of porcine endothelium-derived extracellular vesicles in initiating human porcine-specific T cell immune responses

Authors: Li, Shu, Anwar, Imran J., Canning, Aidan J., Vo-Dinh, Tuan, Kirk, Allan D., Xu, He

Source: In American Journal of Transplantation July 2023 23(7):904-919

Addition of interleukin-6 receptor blockade to carfilzomib-based desensitization in a highly sensitized nonhuman primate model

Authors: Anwar, Imran J., Ezekian, Brian, DeLaura, Isabel, Manook, Miriam, Schroder, Paul, Yoon, Janghoon, Curfman, Verna, Branum, Evelyn, Messina, Julia, Harnois, Melissa, Permar, Sallie R., Farris, Alton B., Kwun, Jean ^*, Knechtle, Stuart J. ^**

Source: In American Journal of Transplantation December 2022 22 Supplement 4:1-11

A novel method for in vitro culture and expansion of nonhuman primate B cells

Authors: DeLaura, Isabel, Schroder, Paul M., Yoon, Janghoon, Ladowski, Joseph, Anwar, Imran J., Ezekian, Brian, Schmitz, Robin, Fitch, Zachary W., Kwun, Jean, Knechtle, Stuart J.

Source: In Journal of Immunological Methods December 2022 511

Liver Transplantation as a New Standard of Care in Patients With Perihilar Cholangiocarcinoma? Results From an International Benchmark Study

Authors: Breuer, Eva, Mueller, Matteo, Doyle, Majella B., Yang, Liu, Darwish Murad, Sarwa, Anwar, Imran J., Merani, Shaheed, Limkemann, Ashley, Jeddou, Heithem, Kim, Steven C., López-López, Victor, Nassar, Ahmed, Hoogwater, Frederik J.H., Vibert, Eric, De Oliveira, Michelle L., Cherqui, Daniel, Porte, Robert J., Magliocca, Joseph F., Fischer, Lutz, Fondevila, Constantino, Zieniewicz, Krzysztof, Ramírez, Pablo, Foley, David P., Boudjema, Karim, Schenk, Austin D., Langnas, Alan N., Knechtle, Stuart, Polak, Wojciech G., Taner, C. Burcin, Chapman, William C., Rosen, Charles B., Gores, Gregory J., Dutkowski, Philipp, Heimbach, Julie K., Clavien, Pierre-Alain

Source: Annals of surgery. 276(5):846-853

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188938994.0x000001&indx=1&recIds=ETOCvdc_100188938994.0x000001

Shifting Clinical Trial Endpoints in Kidney Transplantation: The Rise of Composite Endpoints and Machine Learning to Refine Prognostication

Authors: Anwar, Imran J., Srinivas, Titte R., Gao, Qimeng, Knechtle, Stuart J.

Source: Transplantation. 106(8):1558-1564

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167700493.0x000001&indx=1&recIds=ETOCvdc_100167700493.0x000001

CD154 blockade effectively controls antibody-mediated rejection in highly sensitized nonhuman primate kidney transplant recipients.

Authors: Anwar, Imran J., DeLaura, Isabel, Ladowski, Joseph M., Schilirò, Davide, Gao, Qimeng, Manook, Miriam, Yoon, Janghoon, Belloni, Rafaela, Park, Angela, Schuster, Daniel J., Song, Mingqing, Lin, Lin, Farris, Alton B., Magnani, Diogo, Williams, Kyha, Kwun, Jean, Knechtle, Stuart J.

Source: Science Translational Medicine; 1/1/2025, Vol. 17 Issue 779, p1-14, 14p

Subject Terms: REGULATORY T cells, T helper cells, HLA histocompatibility antigens, B cells, GRAFT rejection, KIDNEY transplantation, IMMUNOSUPPRESSION

Attitudes of patients with renal disease on xenotransplantation: A systematic review

Authors: DeLaura, Isabel, Anwar, Imran J., Ladowski, Joseph, Patino, Alejandra, Cantrell, Sarah, Sanoff, Scott

Source: Xenotransplantation. 30(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184361480.0x000001&indx=1&recIds=ETOCvdc_100184361480.0x000001

Allosensitisation in NHP results in cross‐reactive anti‐SLA antibodies not detected by a lymphocyte‐based flow cytometry crossmatch.

Authors: Ladowski, Joseph M., Chapman, Henry, DeLaura, Isabel, Anwar, Imran J., Yoon, Janghoon, Chen, Zheng, Clark, Adella, Chen, DongFeng, Knechtle, Stuart, Jackson, Annette, Rogers, Bruce, Kwun, Jean

Source: HLA: Immune Response Genetics; Jul2024, Vol. 104 Issue 1, p1-11, 11p

Subject Terms: SKIN grafting, HLA histocompatibility antigens, ERYTHROCYTES, KIDNEY transplantation, HISTOCOMPATIBILITY

Research Highlights

Authors: Anwar, Imran J., Luo, Xunrong

Source: Transplantation. 107(5):1008-1009

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191153677.0x000001&indx=1&recIds=ETOCvdc_100191153677.0x000001

The impact of IdeS (imlifidase) on allo‐specific, xeno‐reactive, and protective antibodies in a sensitized rhesus macaque model.

Authors: DeLaura, Isabel, Zikos, Joanna, Anwar, Imran J., Yoon, Janghoon, Ladowski, Joseph, Jackson, Annette, Van Rompay, Koen, Magnani, Diogo, Knechtle, Stuart J., Kwun, Jean

Source: Xenotransplantation; Jan2024, Vol. 31 Issue 1, p1-11, 11p

Subject Terms: RHESUS monkeys, IMMUNOGLOBULINS, CELL populations, GRAFT rejection, HUMORAL immunity

The endothelial mineralocorticoid receptor: mediator of the switch from vascular health to disease

Authors: Davel, Ana P., Anwar, Imran J., Jaffe, Iris Z.

Source: Current opinion in nephrology and hypertension. 26(2):97-104

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100042325209.0x000001&indx=1&recIds=ETOCvdc_100042325209.0x000001

Research Highlights

Authors: Anwar, Imran J., Luo, Xunrong

Source: Transplantation. 106(11):2097-2098

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173143971.0x000001&indx=1&recIds=ETOCvdc_100173143971.0x000001

Letter to the editor in response to: Measuring success in pig to non‐human‐primate renal xenotransplantation: Systematic review and comparative outcomes analysis of 1051 life sustaining NHP renal allo‐ and xeno‐transplants by Firl and Markmann

Authors: Anwar, Imran J., DeLaura, Isabel, Gao, Qimeng, Knechtle, Stuart, Kwun, Jean

Source: American journal of transplantation. 22(7):1933-1934

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154895987.0x000001&indx=1&recIds=ETOCvdc_100154895987.0x000001

The anti-CD40L monoclonal antibody AT-1501 promotes islet and kidney allograft survival and function in nonhuman primates.

Authors: Anwar, Imran J., Berman, Dora M., DeLaura, Isabel, Gao, Qimeng, Willman, Melissa A., Miller, Allison, Gill, Alan, Gill, Cindy, Perrin, Steve, Ricordi, Camillo, Ruiz, Philip, Song, Mingqing, Ladowski, Joseph M., Kirk, Allan D., Kenyon, Norma S.

Source: Science Translational Medicine; 8/30/2023, Vol. 15 Issue 711, p1-15, 15p

Subject Terms: GRAFT survival, MONOCLONAL antibodies, ISLANDS, PRIMATES, RHESUS monkeys

Design and testing of a humanized porcine donor for xenotransplantation

Authors: Anand, Ranjith P., Layer, Jacob V., Heja, David, Hirose, Takayuki, Lassiter, Grace, Firl, Daniel J., Paragas, Violette B., Akkad, Adam, Chhangawala, Sagar, Colvin, Robert B., Ernst, Russell J., Esch, Nicholas, Getchell, Kristen, Griffin, Alexandra K., Guo, Xiaoyun, Hall, Katherine C., Hamilton, Paula, Kalekar, Lokesh A., Kan, Yinan, Karadagi, Ahmad, Li, Feng, Low, Susan C., Matheson, Rudy, Nehring, Claudia, Otsuka, Ryo, Pandelakis, Matthew, Policastro, Robert A., Pols, Rebecca, Queiroz, Luis, Rosales, Ivy A., Serkin, William T., Stiede, Kathryn, Tomosugi, Toshihide, Xue, Yongqiang, Zentner, Gabriel E., Angeles-Albores, David, Chris Chao, J., Crabtree, Juliet N., Harken, Sierra, Hinkle, Nicole, Lemos, Tania, Li, Mailin, Pantano, Lorena, Stevens, Denise, Subedar, Omar D., Tan, Xiaoqing, Yin, Shiyi, Anwar, Imran J., Aufhauser, David, Capuano, Saverio, Kaufman, Dixon B., Knechtle, Stuart J., Kwun, Jean, Shanmuganayagam, Dhanansayan, Markmann, James F., Church, George M., Curtis, Mike, Kawai, Tatsuo, Youd, Michele E., Qin, Wenning

Source: Nature; October 2023, Vol. 622 Issue: 7982 p393-401, 9p

Successful Prevention of Parastomal Hernia Formation With Intra-Abdominal Funnel-Shaped Mesh.

Authors: Anwar, Imran J., Greenberg, Jacob A.

Source: JAMA Surgery; Nov2024, Vol. 159 Issue 11, p1250-1251, 2p

Complement-targeting therapeutics for ischemiareperfusion injury in transplantation and the potential for ex vivo delivery.

Authors: Delaura, Isabel F., Qimeng Gao, Anwar, Imran J., Abraham, Nader, Kahan, Riley, Hartwig, Matthew G., Barbas, Andrew S.

Source: Frontiers in Immunology; 10/19/2022, Vol. 13, p1-11, 11p

Subject Terms: COMPLEMENT inhibition, COMPLEMENT activation, THERAPEUTICS, REPERFUSION injury, PRESERVATION of organs, tissues, etc.