SCF-SKP2 E3 ubiquitin ligase links mTORC1/ER stress/ISR with YAP activation in murine renal cystogenesis

Authors: Dibyendu K. Panda, Xiuying Bai, Yan Zhang, Nicholas A. Stylianesis, Antonis E. Koromilas, Mark L. Lipman, Andrew C. Karaplis

Source: The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)

Subject Terms: Nephrology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/805150cc024648f6bb0b0df97758d5bb

The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer

Authors: Nour Ghaddar, Shuo Wang, Bethany Woodvine, Jothilatha Krishnamoorthy, Vincent van Hoef, Cedric Darini, Urszula Kazimierczak, Nicolas Ah-son, Helmuth Popper, Myriam Johnson, Leah Officer, Ana Teodósio, Massimo Broggini, Koren K. Mann, Maria Hatzoglou, Ivan Topisirovic, Ola Larsson, John Le Quesne, Antonis E. Koromilas

Source: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c5184c726c2a4e1fa460c06a009a5df9

An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy

Authors: Cedric Darini, Nour Ghaddar, Catherine Chabot, Gloria Assaker, Siham Sabri, Shuo Wang, Jothilatha Krishnamoorthy, Marguerite Buchanan, Adriana Aguilar-Mahecha, Bassam Abdulkarim, Jean Deschenes, Jose Torres, Josie Ursini-Siegel, Mark Basik, Antonis E. Koromilas

Source: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7ecf6c59b1264893ab9910b75de10e72

The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression

Authors: Ryuhjin Ahn, Valérie Sabourin, Alicia M. Bolt, Steven Hébert, Stephanie Totten, Nicolas De Jay, Maria Carolina Festa, Yoon Kow Young, Young Kyuen Im, Tony Pawson, Antonis E. Koromilas, William J. Muller, Koren K. Mann, Claudia L. Kleinman, Josie Ursini-Siegel

Source: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/4564af3090224e7180bdbbc6e315baaa

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

Authors: Valentina Gandin, Laia Masvidal, Marie Cargnello, Laszlo Gyenis, Shannon McLaughlan, Yutian Cai, Clara Tenkerian, Masahiro Morita, Preetika Balanathan, Olivier Jean-Jean, Vuk Stambolic, Matthias Trost, Luc Furic, Louise Larose, Antonis E. Koromilas, Katsura Asano, David Litchfield, Ola Larsson, Ivan Topisirovic

Source: Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/3b23e374915e42abafd814b872f5dd1d

Detection of Lung Tumor Progression in Mice by Ultrasound Imaging

Authors: Nour Ghaddar, author^{1, 2}, Shuo Wang, author¹, Véronique Michaud, author¹, Urszula Kazimierczak, author^{1, 3}, Nicolas Ah-son, author¹, Antonis E. Koromilas, author^{1, 4}

Source: Journal of Visualized Experiments. (156)

Availability: http://www.jove.com/video/60565

Protein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytes.

Authors: Ahmed Bettaieb, Kosuke Matsuo, Izumi Matsuo, Shuo Wang, Ramzi Melhem, Antonis E Koromilas, Fawaz G Haj

Source: PLoS ONE, Vol 7, Iss 4, p e34412 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3317973?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/870265da77d7448ca41eb4e49778d137

Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1.

Authors: Shuo Wang, Jennifer F Raven, Joan E Durbin, Antonis E Koromilas

Source: PLoS ONE, Vol 3, Iss 10, p e3476 (2008)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2568943?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c64e26c3ee4e418594e2c12995c8e02f