Adjunctive rosiglitazone treatment for severe pediatric malaria: A randomized placebo-controlled trial in Mozambican children

Authors: Rosauro Varo, Valerie M. Crowley, Humberto Mucasse, Antonio Sitoe, Justina Bramugy, Lena Serghides, Andrea M. Weckman, Clara Erice, Rubao Bila, Pio Vitorino, Campos Mucasse, Marta Valente, Sara Ajanovic, Núria Balanza, Kathleen Zhong, Yiovanna Derpsch, Melissa Gladstone, Alfredo Mayor, Quique Bassat, Kevin C. Kain

Source: International Journal of Infectious Diseases, Vol 139, Iss , Pp 34-40 (2024)

Subject Terms: Adjunctive, Treatment, Plasmodium falciparum, Malaria, Severe, Rosiglitazone, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971223007920; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/35a487633f2b42adae155c4ba0365d55

Endothelial transcriptomic analysis identifies biomarkers of severe and cerebral malaria

Authors: Cláudia Gomes, Rosauro Varo, Miquel Duran-Frigola, Antonio Sitoe, Rubão Bila, Sonia Machevo, Alfredo Mayor, Quique Bassat, Ana Rodriguez

Source: JCI Insight, Vol 8, Iss 22 (2023)

Subject Terms: Infectious disease, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/860cefaf2ea545ce90cd8443e088c558

Provider adherence to clinical care recommendations for infants and children who died in seven low- and middle-income countries in the Child Health and Mortality Prevention Surveillance (CHAMPS) networkResearch in context

Authors: Chris A. Rees, Kitiezo Aggrey Igunza, Zachary J. Madewell, Victor Akelo, Dickens Onyango, Shams El Arifeen, Emily S. Gurley, Mohammad Zahid Hossain, Afruna Rahman, Muntasir Alam, J. Anthony G. Scott, Nega Assefa, Lola Madrid, Anteneh Belachew, Haleluya Leulseged, Karen L. Kotloff, Samba O. Sow, Milagritos D. Tapia, Adama Mamby Keita, Diakaridia Sidibe, Antonio Sitoe, Rosauro Varo, Sara Ajanovic, Quique Bassat, Inácio Mandomando, Beth A. Tippett Barr, Ikechukwu Ogbuanu, Carrie Jo Cain, Ima-Abasi Bassey, Ronita Luke, Khadija Gassama, Shabir Madhi, Ziyaad Dangor, Sana Mahtab, Sithembiso Velaphi, Jeanie du Toit, Portia C. Mutevedzi, Dianna M. Blau, Robert F. Breiman, Cynthia G. Whitney, Fatima Solomon, Gillian Sorour, Hennie Lombaard, Jeannette Wadula, Karen Petersen, Martin Hale, Nelesh P. Govender, Peter J. Swart, Sanjay G. Lala, Richard Chawana, Yasmin Adam, Amy Wise, Ashleigh Fritz, Nellie Myburgh, Pedzisai Ndagurwa, Cleopas Hwinya, Sanwarul Bari, Shahana Parveen, Mohammed Kamal, A.S.M. Nawshad Uddin Ahmed, Mahbubul Hoque, Saria Tasnim, Ferdousi Islam, Farida Ariuman, Mohammad Mosiur Rahman, Ferdousi Begum, K. Zaman, Mustafizur Rahman, Dilruba Ahmed, Meerjady Sabrina Flora, Tahmina Shirin, Mahbubur Rahman, Joseph Oundo, Alexander M. Ibrahim, Fikremelekot Temesgen, Tadesse Gure, Addisu Alemu, Melisachew Mulatu Yeshi, Mahlet Abayneh Gizaw, Stian Orlien, Solomon Ali, Peter Otieno, Peter Nyamthimba Onyango, Janet Agaya, Richard Oliech, Joyce Akinyi Were, Dickson Gethi, Sammy Khagayi, George Aol, Thomas Misore, Harun Owuor, Christopher Mugah, Bernard Oluoch, Christine Ochola, Sharon M. Tennant, Carol L. Greene, Ashka Mehta, J. Kristie Johnson, Brigitte Gaume, Rima Koka, Karen D. Fairchild, Diakaridia Kone, Doh Sanogo, Uma U. Onwuchekwa, Nana Kourouma, Seydou Sissoko, Cheick Bougadari Traore, Jane Juma, Kounandji Diarra, Awa Traore, Tiéman Diarra, Kiranpreet Chawla, Tacilta Nhampossa, Zara Manhique, Sibone Mocumbi, Clara Menéndez, Khátia Munguambe, Ariel Nhacolo, Maria Maixenchs, Andrew Moseray, Fatmata Bintu Tarawally, Martin Seppeh, Ronald Mash, Julius Ojulong, Babatunde Duduyemi, James Bunn, Alim Swaray-Deen, Joseph Bangura, Amara Jambai, Margaret Mannah, Okokon Ita, Cornell Chukwuegbo, Sulaiman Sannoh, Princewill Nwajiobi, Dickens Kowuor, Erick Kaluma, Oluseyi Balogun, Solomon Samura, Samuel Pratt, Francis Moses, Tom Sesay, James Squire, Joseph Kamanda Sesay, Osman Kaykay, Binyam Halu, Hailemariam Legesse, Francis Smart, Sartie Kenneh, Soter Ameh, Jana Ritter, Tais Wilson, Jonas Winchell, Jakob Witherbee, Navit T. Salzberg, Jeffrey P. Koplan, Margaret Basket, Ashutosh Wadhwa, Kyu Han Lee, Valentine Wanga, Roosecelis Martines, Shamta Warang, Maureen Diaz, Jessica Waller, Shailesh Nair, Lucy Liu, Courtney Bursuc, Kristin LaHatte, Sarah Raymer, John Blevins, Solveig Argeseanu, Kurt Vyas, Manu Bhandari

Source: EClinicalMedicine, Vol 63, Iss , Pp 102198- (2023)

Subject Terms: Childhood, Mortality, Clinical care, Guideline adherence, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537023003759; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/7bbde38ed56a44c89b6d96f1be3aa920

Causes of death identified in neonates enrolled through Child Health and Mortality Prevention Surveillance (CHAMPS), December 2016 –December 2021

Authors: Sana Mahtab, Shabir A. Madhi, Vicky L. Baillie, Toyah Els, Bukiwe Nana Thwala, Dickens Onyango, Beth A. Tippet-Barr, Victor Akelo, Kitiezo Aggrey Igunza, Richard Omore, Shams El Arifeen, Emily S. Gurley, Muntasir Alam, Atique Iqbal Chowdhury, Afruna Rahman, Quique Bassat, Inacio Mandomando, Sara Ajanovic, Antonio Sitoe, Rosauro Varo, Samba O. Sow, Karen L. Kotloff, Henry Badji, Milagritos D. Tapia, Cheick B. Traore, Ikechukwu U. Ogbuanu, James Bunn, Ronita Luke, Sulaiman Sannoh, Alim Swarray-Deen, Nega Assefa, J. Anthony G. Scott, Lola Madrid, Dadi Marami, Surafel Fentaw, Maureen H. Diaz, Roosecelis B. Martines, Robert F. Breiman, Zachary J. Madewell, Dianna M. Blau, Cynthia G. Whitney

Source: PLOS Global Public Health, Vol 3, Iss 3 (2023)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027211/?tool=EBI; https://doaj.org/toc/2767-3375

Access URL: https://doaj.org/article/c306a2e7cd9c43cdb04eb5dbb09df71d

Prognostic accuracy of biomarkers of immune and endothelial activation in Mozambican children hospitalized with pneumonia

Authors: Núria Balanza, Clara Erice, Michelle Ngai, Chloe R. McDonald, Andrea M. Weckman, Julie Wright, Melissa Richard-Greenblatt, Rosauro Varo, Elisa López-Varela, Antonio Sitoe, Pio Vitorino, Justina Bramugy, Miguel Lanaspa, Sozinho Acácio, Lola Madrid, Bàrbara Baro, Kevin C. Kain, Quique Bassat

Source: PLOS Global Public Health, Vol 3, Iss 2 (2023)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021812/?tool=EBI; https://doaj.org/toc/2767-3375

Access URL: https://doaj.org/article/b2a923bd2b16409aa3d68478cfbae8b8

Prognostic accuracy of biomarkers of immune and endothelial activation in Mozambican children hospitalized with pneumonia.

Authors: Núria Balanza, Clara Erice, Michelle Ngai, Chloe R McDonald, Andrea M Weckman, Julie Wright, Melissa Richard-Greenblatt, Rosauro Varo, Elisa López-Varela, Antonio Sitoe, Pio Vitorino, Justina Bramugy, Miguel Lanaspa, Sozinho Acácio, Lola Madrid, Bàrbara Baro, Kevin C Kain, Quique Bassat

Source: PLOS Global Public Health, Vol 3, Iss 2, p e0001553 (2023)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/2767-3375

Access URL: https://doaj.org/article/b2155be86a76412cbd2914a9868451e0

Causes of death identified in neonates enrolled through Child Health and Mortality Prevention Surveillance (CHAMPS), December 2016 -December 2021.

Authors: Sana Mahtab, Shabir A Madhi, Vicky L Baillie, Toyah Els, Bukiwe Nana Thwala, Dickens Onyango, Beth A Tippet-Barr, Victor Akelo, Kitiezo Aggrey Igunza, Richard Omore, Shams El Arifeen, Emily S Gurley, Muntasir Alam, Atique Iqbal Chowdhury, Afruna Rahman, Quique Bassat, Inacio Mandomando, Sara Ajanovic, Antonio Sitoe, Rosauro Varo, Samba O Sow, Karen L Kotloff, Henry Badji, Milagritos D Tapia, Cheick B Traore, Ikechukwu U Ogbuanu, James Bunn, Ronita Luke, Sulaiman Sannoh, Alim Swarray-Deen, Nega Assefa, J Anthony G Scott, Lola Madrid, Dadi Marami, Surafel Fentaw, Maureen H Diaz, Roosecelis B Martines, Robert F Breiman, Zachary J Madewell, Dianna M Blau, Cynthia G Whitney, CHAMPS Consortium

Source: PLOS Global Public Health, Vol 3, Iss 3, p e0001612 (2023)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/2767-3375

Access URL: https://doaj.org/article/597ac256dd7f4d9aaca13eca5fead733

Plasmodium falciparum sexual conversion rates can be affected by artemisinin-based treatment in naturally infected malaria patients

Authors: Harvie P. Portugaliza, H. Magloire Natama, Pieter Guetens, Eduard Rovira-Vallbona, Athanase M. Somé, Aida Millogo, D. Florence Ouédraogo, Innocent Valéa, Hermann Sorgho, Halidou Tinto, Nguyen van Hong, Antonio Sitoe, Rosauro Varo, Quique Bassat, Alfred Cortés, Anna Rosanas-Urgell

Source: EBioMedicine, Vol 83, Iss , Pp 104198- (2022)

Subject Terms: Plasmodium falciparum, Sexual conversion, Artemisinin, Malaria transmission, pfap2-g, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396422003802; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/c8aff7f8de5e45eebd91282b7d06570d

Plasma MicroRNA Profiling of Plasmodium falciparum Biomass and Association with Severity of Malaria Disease

Authors: Himanshu Gupta, Mercedes Rubio, Antonio Sitoe, Rosauro Varo, Pau Cisteró, Lola Madrid, Inocencia Cuamba, Alfons Jimenez, Xavier Martiáñez-Vendrell, Diana Barrios, Lorena Pantano, Allison Brimacombe, Mariona Bustamante, Quique Bassat, Alfredo Mayor

Source: Emerging Infectious Diseases, Vol 27, Iss 2, Pp 430-442 (2021)

Subject Terms: Plasmodium falciparum, miRNA, malaria, severe malaria, biomarkers, next-generation sequencing, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/27/2/19-1795_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/95fe2e9beb2342e2a79de088dedac99d

Post-malarial anemia in Mozambican children treated with quinine or artesunate: A retrospective observational study

Authors: Rosauro Varo, Llorenç Quintó, Antonio Sitoe, Lola Madrid, Sozinho Acácio, Pio Vitorino, Ana Marta Valente, Alfredo Mayor, Daniel Camprubí, Jose Muñoz, Gizela Bambo, Eusebio Macete, Clara Menéndez, Pedro L. Alonso, Pedro Aide, Quique Bassat

Source: International Journal of Infectious Diseases, Vol 96, Iss , Pp 655-662 (2020)

Subject Terms: Severe malaria, Anemia, Hemolysis, Artesunate, Quinine, African children, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971220303969; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/b5af346c94eb4014980476fdd23b28ae

Postmortem investigations and identification of multiple causes of child deaths: An analysis of findings from the Child Health and Mortality Prevention Surveillance (CHAMPS) network.

Authors: Robert F Breiman, Dianna M Blau, Portia Mutevedzi, Victor Akelo, Inacio Mandomando, Ikechukwu U Ogbuanu, Samba O Sow, Lola Madrid, Shams El Arifeen, Mischka Garel, Nana Bukiwe Thwala, Dickens Onyango, Antonio Sitoe, Ima-Abasi Bassey, Adama Mamby Keita, Addisu Alemu, Muntasir Alam, Sana Mahtab, Dickson Gethi, Rosauro Varo, Julius Ojulong, Solomon Samura, Ashka Mehta, Alexander M Ibrahim, Afruna Rahman, Pio Vitorino, Vicky L Baillie, Janet Agaya, Milagritos D Tapia, Nega Assefa, Atique Iqbal Chowdhury, J Anthony G Scott, Emily S Gurley, Karen L Kotloff, Amara Jambai, Quique Bassat, Beth A Tippett-Barr, Shabir A Madhi, Cynthia G Whitney, CHAMPS Consortium

Source: PLoS Medicine, Vol 18, Iss 9, p e1003814 (2021)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/ef564d1c67214749a85426496f56e460

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis.

Authors: Andria Mousa, Abdullah Al-Taiar, Nicholas M Anstey, Cyril Badaut, Bridget E Barber, Quique Bassat, Joseph D Challenger, Aubrey J Cunnington, Dibyadyuti Datta, Chris Drakeley, Azra C Ghani, Victor R Gordeuk, Matthew J Grigg, Pierre Hugo, Chandy C John, Alfredo Mayor, Florence Migot-Nabias, Robert O Opoka, Geoffrey Pasvol, Claire Rees, Hugh Reyburn, Eleanor M Riley, Binal N Shah, Antonio Sitoe, Colin J Sutherland, Philip E Thuma, Stefan A Unger, Firmine Viwami, Michael Walther, Christopher J M Whitty, Timothy William, Lucy C Okell

Source: PLoS Medicine, Vol 17, Iss 10, p e1003359 (2020)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/ba8efe1bc73045abb15eedf4a63503a8

Adjunctive therapy for severe malaria: a review and critical appraisal

Authors: Rosauro Varo, Valerie M. Crowley, Antonio Sitoe, Lola Madrid, Lena Serghides, Kevin C. Kain, Quique Bassat

Source: Malaria Journal, Vol 17, Iss 1, Pp 1-18 (2018)

Subject Terms: Adjunctive, Treatment, Plasmodium falciparum, Malaria, Severe, Cerebral, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-018-2195-7; https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/43b697e14bef4c9d9cbaadc636043e40

Continuous determination of blood glucose in children admitted with malaria in a rural hospital in Mozambique

Authors: Lola Madrid, Antonio Sitoe, Rosauro Varo, Tacilta Nhampossa, Miguel Lanaspa, Abel Nhama, Sozinho Acácio, Isolina Riaño, Aina Casellas, Quique Bassat

Source: Malaria Journal, Vol 16, Iss 1, Pp 1-12 (2017)

Subject Terms: Hypoglycaemia, Blood glucose, Hyperglycaemia, Continuous glucose monitor, Malaria, Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-017-1840-x; https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/a6ba5a63772d4e95bd014f69c0c2377e

Safety and tolerability of adjunctive rosiglitazone treatment for children with uncomplicated malaria

Authors: Rosauro Varo, Valerie M. Crowley, Antonio Sitoe, Lola Madrid, Lena Serghides, Rubao Bila, Helio Mucavele, Alfredo Mayor, Quique Bassat, Kevin C. Kain

Source: Malaria Journal, Vol 16, Iss 1, Pp 1-8 (2017)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12936-017-1858-0; https://doaj.org/toc/1475-2875

Access URL: https://doaj.org/article/22664b9c57514e5b95e305f37e421e02

Continuous Glucose Monitoring in Resource-Constrained Settings for Hypoglycaemia Detection: Looking at the Problem from the Other Side of the Coin

Authors: Rubao Bila, Rosauro Varo, Lola Madrid, Antonio Sitoe, Quique Bassat

Source: Biosensors, Vol 8, Iss 2, p 43 (2018)

Subject Terms: continuous glucose monitoring, hypoglycaemia, low-income countries, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.mdpi.com/2079-6374/8/2/43; https://doaj.org/toc/2079-6374

Access URL: https://doaj.org/article/b90b7301cbcd4d1783352b49f22944a5

Child Health and Mortality Prevention Surveillance (CHAMPS): Manhiça site description, Mozambique [version 2; peer review: 2 approved]

Authors: Fabíola Fernandes, Maria Maixenchs, Inácio Mandomando, Charfudin Sacoor, Ariel Nhacolo, Pio Vitorino, Rita Mabunda, Khátia Munguambe, Edgar Jamisse, Quique Bassat, Marcelino Garrine, Elísio Xerinda, Amílcar Magaço, Carla Carrilho, António Sitoe, Tacilta Nhampossa, Percina Chirinda, Natalia Rakislova, Bento Nhancale, Sara Ajanovic, Arsénio Nhacolo, Arsénia Massinga, Marta Valente, Clara Menéndez, Justina Bramugy, Rosauro Varo, Jaume Ordi

Source: Gates Open Research, Vol 7 (2024)

Subject Terms: Manhiça site description, Health and Demographic Surveillance System, morbidity surveillance, Mozambique, child mortality, post-mortem, eng, Medicine

File Description: electronic resource

Relation: https://gatesopenresearch.org/articles/7-4/v2; https://doaj.org/toc/2572-4754

Access URL: https://doaj.org/article/c3914af9ed41487ab0aab7c1db64c3b5

Child Health and Mortality Prevention Surveillance (CHAMPS): Manhiça site description, Mozambique [version 3; peer review: 2 approved]

Authors: Fabíola Fernandes, Maria Maixenchs, Inácio Mandomando, Charfudin Sacoor, Ariel Nhacolo, Pio Vitorino, Rita Mabunda, Khátia Munguambe, Edgar Jamisse, Quique Bassat, Marcelino Garrine, Elísio Xerinda, Amílcar Magaço, Carla Carrilho, António Sitoe, Tacilta Nhampossa, Percina Chirinda, Natalia Rakislova, Bento Nhancale, Sara Ajanovic, Arsénio Nhacolo, Arsénia Massinga, Marta Valente, Clara Menéndez, Justina Bramugy, Rosauro Varo, Jaume Ordi

Source: Gates Open Research, Vol 7 (2024)

Subject Terms: Manhiça site description, Health and Demographic Surveillance System, morbidity surveillance, Mozambique, child mortality, post-mortem, eng, Medicine

File Description: electronic resource

Relation: https://gatesopenresearch.org/articles/7-4/v3; https://doaj.org/toc/2572-4754

Access URL: https://doaj.org/article/0f9114ecb9624f0698e1e45a96feef26

Child Health and Mortality Prevention Surveillance (CHAMPS): Manhiça site description, Mozambique [version 1; peer review: 2 approved]

Authors: Fabíola Fernandes, Maria Maixenchs, Inácio Mandomando, Charfudin Sacoor, Ariel Nhacolo, Pio Vitorino, Rita Mabunda, Khátia Munguambe, Edgar Jamisse, Quique Bassat, Marcelino Garrine, Elísio Xerinda, Amílcar Magaço, Carla Carrilho, António Sitoe, Tacilta Nhampossa, Percina Chirinda, Natalia Rakislova, Bento Nhancale, Sara Ajanovic, Arsénio Nhacolo, Arsénia Massinga, Marta Valente, Clara Menéndez, Justina Bramugy, Rosauro Varo, Jaume Ordi

Source: Gates Open Research, Vol 7 (2023)

Subject Terms: Manhiça site description, Health and Demographic Surveillance System, morbidity surveillance, Mozambique, child mortality, post-mortem, eng, Medicine

File Description: electronic resource

Relation: https://gatesopenresearch.org/articles/7-4/v1; https://doaj.org/toc/2572-4754

Access URL: https://doaj.org/article/bcf50b7562494e039fbc053d802d026d

Experiences of parents and caretakers going through the consent process to perform minimally invasive tissue sampling (MITS) on their deceased children in Quelimane, Mozambique: A qualitative study.

Authors: Amilcar Magaço, Maria Maixenchs, Yury Macete, Nelson Escritório, Raquel Mucor, António Calia, António Sitoe, Elisio Xirinda, Pio Vitorino, Mischka Garel, Robert F Breiman, Agbessi Amouzou, Quique Bassat, Inácio Mandomando, John Blevins, Khátia Munguambe

Source: PLoS ONE, Vol 18, Iss 6, p e0286785 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0286785&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f0fefefcc70f4a6ba2a77ae073d57819