Proximal tubule-on-chip as a model for predicting cation transport and drug transporter dynamics

Authors: Isy Petit, Quentin Faucher, Jean-Sébastien Bernard, Perrine Giunchi, Antoine Humeau, François-Ludovic Sauvage, Pierre Marquet, Nicolas Védrenne, Florent Di Meo

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-12 (2025)

Subject Terms: Organ-On-a-Chip, Pharmacokinetics, Drug membrane transporters, Proximal tubule-On-a-Chip, Drug-Drug Interactions, Drug-Endogenous metabolite Interactions, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/cfdf4b852a454451b8699495f37a24ff

Tacrolimus Dose Requirement in De Novo Adult Kidney Transplant Patients Treated With Adoport® Can Be Anticipated

Authors: Pierre Marquet, Dany Anglicheau, Antoine Humeau, Sofian Adrouche, Lakhdar Saada, Julie Bisiaux, Sara Guillemin, Audrey Lardy-Cléaud, Lionel Rostaing

Source: Transplant International, Vol 37 (2024)

Subject Terms: tacrolimus, pharmacokinetic variability, diet, ethnicity, genetic polymorphisms, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13495/full; https://doaj.org/toc/1432-2277

Access URL: https://doaj.org/article/4ed9a91435b44ababa90035d64d19c85

In vitro and in vivo models define a molecular signature reference for human embryonic notochordal cells

Authors: Julie Warin, Nicolas Vedrenne, Vivian Tam, Mengxia Zhu, Danqing Yin, Xinyi Lin, Bluwen Guidoux-D’halluin, Antoine Humeau, Luce Roseiro, Lily Paillat, Claire Chédeville, Caroline Chariau, Frank Riemers, Markus Templin, Jérôme Guicheux, Marianna A. Tryfonidou, Joshua W.K. Ho, Laurent David, Danny Chan, Anne Camus

Source: iScience, Vol 27, Iss 2, Pp 109018- (2024)

Subject Terms: Biological sciences, Biology of human development, Developmental biology, Natural sciences, Omics, Transcriptomics, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224002396; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/4fbbade5e5f24b0385edeacb652fc23d

Alternative to animal experimentation in pharmacology teaching: Development and validation of an equivalent digital learning tool

Authors: Roland Lawson, Sophie Leymarie, Claire Nikitopoulos, Antoine Humeau, Hichem Bouchenaki, Jean‐Luc Duroux, Laurent Fourcade, Sandrine Karam, Nicolas Picard, Claire Demiot

Source: Pharmacology Research & Perspectives, Vol 10, Iss 1, Pp n/a-n/a (2022)

Subject Terms: animal experimentation, digital teaching tool, knowledge acquisition, motivation, preclinical pharmacology teaching, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2052-1707

Access URL: https://doaj.org/article/2fa992f037c740ecad0240d40bf3a596