Regulation of adipocyte differentiation and lipid metabolism by novel synthetic chromenes exploring anti-obesity and broader therapeutic potential

Authors: Kewalin Inthanon, Natthawut Wong-a-nan, Srisulak Dheeranupattana, Andres Garcia Guerra, Neal M. Davies, Chatchai Kesornpun, Sasithorn Sangher, Prasat Kittakoop

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-25 (2025)

Subject Terms: Chromene, Anti-obesity agent, Adipogenesis, Lipolysis, 3T3-L1, Adipocyte, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/865bc7e17eb3460f960eb8caeccd96b1

Quantitative proteomics and targeted metabolomics reveal the role of Cassia siamea L. extract in the response to high-fat diet-induced obesity in Drosophila

Authors: Ananya Dechakhamphu, Nattapong Wongchum, Theeraphan Chumroenphat, Alongklod Tanomtong, Sirithon Siriamornpun

Source: Phytomedicine Plus, Vol 5, Iss 1, Pp 100743- (2025)

Subject Terms: Anti-obesity agent, Plant extract, Biological product, Obesity, Animal model, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667031325000168; https://doaj.org/toc/2667-0313

Access URL: https://doaj.org/article/b40b1f9b061643839a16807baa47f47e

Drug Metabolism/Transport and Pharmacokinetics

Contributors: Song, Im-Sook

Subject Terms: tofacitinib, dose-dependent pharmacokinetics, hepatic and intestinal first-pass effect, rats, catalposide, in vitro human metabolism, UDP-glucuronosyltransferase, sulfotransferase, carboxylesterase, celecoxib, drug–drug interaction, fluorescence, HPLC, metabolism, repaglinide, HSG4112, anti-obesity agent, stereoselectivity, pharmacokinetics, compound K, protopanaxadiol (PPD), biliary excretion, intestinal metabolism, Carthamus tinctorius extract, notoginseng total saponins, comparative pharmacokinetic study, large volume direct injection, compatibility mechanism, mertansine, human hepatocytes, cytochrome P450, UDP-glucuronosyltransferases, sodium-glucose cotransporter 2 (SGLT2) inhibitors, DWP16001, kidney distribution, inhibition mode, diabetes, transporter-enzyme interplay, influx transporter, efflux transporter, physiologically based pharmacokinetic model, cytochrome P450 enzymes, tiropramide, healthy Korean subjects, modeling, population pharmacokinetic, quercetin, breast cancer resistance protein, inhibitor, prazosin, sulfasalazine, kinetic analysis, food–drug interactions, Caco-2, EpiIntestinal, first-pass, P-gp, BCRP, drug transporter, CYP3A4, oral availability, automatization, drug absorption, drug dosing, head-and-neck cancer, real-time measurements, taxanes, tissue engineering, UHPLC-MS/MS, metformin, verapamil, drug interaction, organic cation transporter 2, renal excretion, acute renal failure, gentamicin, cisplatin, hepatic CYP3A1(23), creatinine clearance, renal clearance, nonrenal clearance, Medicine and Nursing, Manufacturing industries

File Description: image/jpeg

Access URL: https://directory.doabooks.org/handle/20.500.12854/77070
https://mdpi.com/books/pdfview/book/4688

Hydroethanolic Cyperus rotundus L. extract exhibits anti-obesity property and increases lifespan expectancy in Drosophila melanogaster fed a high-fat diet

Authors: Nattapong Wongchum, Ananya Dechakhamphu, Panatda Panya, Somchai Pinlaor, Sitthisak Pinmongkhonkul, Alongklod Tanomtong

Source: Journal of HerbMed Pharmacology, Vol 11, Iss 2, Pp 296-304 (2022)

Subject Terms: herbal medicine, anti-obesity agent, oxidative stress, longevity, animal model, Medicine (General), R5-920, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://herbmedpharmacol.com/PDF/jhp-11-296.pdf; https://doaj.org/toc/2345-5004

Access URL: https://doaj.org/article/8ca19c28d4514694a4f9c48931c3b86e

Pancreatic Lipase inhibition assay of various extracts of leaves of Murraya Koenigii in southern areas of Goa

Authors: Pinto Pearl, Alva Priya D., Chinnarasu Sivaprakasam, Sadasivam Mohanraj, Cojandaraj Louis

Source: BIO Web of Conferences, Vol 86, p 01055 (2024)

Subject Terms: murraya koenigii, pancreatic lipase inhibitory activity, soxhlet extraction, p-nitrophenyl butyrate, anti-obesity agent, Microbiology, QR1-502, Physiology, QP1-981, Zoology, QL1-991

File Description: electronic resource

Relation: https://www.bio-conferences.org/articles/bioconf/pdf/2024/05/bioconf_rtbs2024_01055.pdf; https://doaj.org/toc/2117-4458

Access URL: https://doaj.org/article/9da7c9eee9454555a5b199283a30ad39

Edible Mushrooms as Novel Myco-Therapeutics: Effects on Lipid Level, Obesity and BMI

Authors: Faheem Mustafa, Hitesh Chopra, Atif Amin Baig, Satya Kumar Avula, Sony Kumari, Tapan Kumar Mohanta, Muthupandian Saravanan, Awdhesh Kumar Mishra, Nanaocha Sharma, Yugal Kishore Mohanta

Source: Journal of Fungi, Vol 8, Iss 2, p 211 (2022)

Subject Terms: edible mushroom, obesity, lipid profile, body mass index, gut microbiota, anti-obesity agent, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2309-608X/8/2/211; https://doaj.org/toc/2309-608X

Access URL: https://doaj.org/article/04c12066ee074ca0bb1e93388f44e6d4

Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent

Authors: In Yong Bae, Min Sun Choi, Young Seok Ji, Sang-Ku Yoo, Kyungil Kim, Hye Hyun Yoo

Source: Pharmaceutics, Vol 12, Iss 2, p 127 (2020)

Subject Terms: hsg4112, anti-obesity agent, stereoselectivity, pharmacokinetics, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/12/2/127; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/f128c33741f24471912c105d81dd1770

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