Prognostic impact of the absence of biallelic deletion at the TRG locus for pediatric patients with T-cell acute lymphoblastic leukemia treated on the Medical Research Council UK Acute Lymphoblastic Leukemia 2003 trial

Authors: Nadine Farah, Amy A Kirkwood, Sunniyat Rahman, Theresa Leon, Sarah Jenkinson, Rosemary E. Gale, Katharine Patrick, Jeremy Hancock, Sujith Samarasinghe, David C. Linch, Anthony V Moorman, Nicholas Goulden, Ajay Vora, Marc R. Mansour

Source: Haematologica, Vol 103, Iss 7 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8532; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/2fd597fa6b7a4851a807edf8f7f8b49a

Outcome of central nervous system relapses in childhood acute lymphoblastic leukaemia--prospective open cohort analyses of the ALLR3 trial.

Authors: Ashish Narayan Masurekar, Catriona A Parker, Milensu Shanyinde, Anthony V Moorman, Jeremy P Hancock, Rosemary Sutton, Philip J Ancliff, Mary Morgan, Nicholas J Goulden, Chris Fraser, Peter M Hoogerbrugge, Tamas Revesz, Philip J Darbyshire, Shekhar Krishnan, Sharon B Love, Vaskar Saha

Source: PLoS ONE, Vol 9, Iss 10, p e108107 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4184796?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/a33a747b941a4d608fce934190131089

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

Authors: Jayaram Vijayakrishnan, James Studd, Peter Broderick, Ben Kinnersley, Amy Holroyd, Philip J. Law, Rajiv Kumar, James M. Allan, Christine J. Harrison, Anthony V. Moorman, Ajay Vora, Eve Roman, Sivaramakrishna Rachakonda, Sally E. Kinsey, Eamonn Sheridan, Pamela D. Thompson, Julie A. Irving, Rolf Koehler, Per Hoffmann, Markus M. Nöthen, Stefanie Heilmann-Heimbach, Karl-Heinz Jöckel, Douglas F. Easton, Paul D. P. Pharaoh, Alison M. Dunning, Julian Peto, Frederico Canzian, Anthony Swerdlow, Rosalind A. Eeles, ZSofia Kote-Jarai, Kenneth Muir, Nora Pashayan, The PRACTICAL Consortium, Mel Greaves, Martin Zimmerman, Claus R. Bartram, Martin Schrappe, Martin Stanulla, Kari Hemminki, Richard S. Houlston

Source: Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/6a850276ab0d4ba1a6215db9280b774f

Author Correction: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

Authors: Jayaram Vijayakrishnan, James Studd, Peter Broderick, Ben Kinnersley, Amy Holroyd, Philip J. Law, Rajiv Kumar, James M. Allan, Christine J. Harrison, Anthony V. Moorman, Ajay Vora, Eve Roman, Sivaramakrishna Rachakonda, Sally E. Kinsey, Eamonn Sheridan, Pamela D. Thompson, Julie A. Irving, Rolf Koehler, Per Hoffmann, Markus M. Nöthen, Stefanie Heilmann-Heimbach, Karl-Heinz Jöckel, Douglas F. Easton, Paul D. P. Pharaoh, Alison M. Dunning, Julian Peto, Frederico Canzian, Anthony Swerdlow, Rosalind A. Eeles, Zsofia Kote-Jarai, Kenneth Muir, Nora Pashayan, The PRACTICAL consortium, Mel Greaves, Martin Zimmerman, Claus R. Bartram, Martin Schrappe, Martin Stanulla, Kari Hemminki, Richard S. Houlston

Source: Nature Communications, Vol 10, Iss 1, Pp 1-3 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/3b6f8efa9fc34ebcb4db4d75611e74bc

Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

Authors: Zhaohui Gu, Michelle Churchman, Kathryn Roberts, Yongjin Li, Yu Liu, Richard C. Harvey, Kelly McCastlain, Shalini C. Reshmi, Debbie Payne-Turner, Ilaria Iacobucci, Ying Shao, I-Ming Chen, Marcus Valentine, Deqing Pei, Karen L. Mungall, Andrew J. Mungall, Yussanne Ma, Richard Moore, Marco Marra, Eileen Stonerock, Julie M. Gastier-Foster, Meenakshi Devidas, Yunfeng Dai, Brent Wood, Michael Borowitz, Eric E. Larsen, Kelly Maloney, Leonard A. Mattano Jr, Anne Angiolillo, Wanda L. Salzer, Michael J. Burke, Francesca Gianni, Orietta Spinelli, Jerald P. Radich, Mark D. Minden, Anthony V. Moorman, Bella Patel, Adele K. Fielding, Jacob M. Rowe, Selina M. Luger, Ravi Bhatia, Ibrahim Aldoss, Stephen J. Forman, Jessica Kohlschmidt, Krzysztof Mrózek, Guido Marcucci, Clara D. Bloomfield, Wendy Stock, Steven Kornblau, Hagop M. Kantarjian, Marina Konopleva, Elisabeth Paietta, Cheryl L. Willman, Mignon L. Loh, Stephen P. Hunger, Charles G. Mullighan

Source: Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a47717c88ef24c69ad243e26e4c2ed5d

Breakpoints of variant 9;22 translocations in chronic myeloid leukemia locate preferentially in the CG-richest regions of the genome.

Authors: Andrew M. Fisher, Paul Strike, Claire Scott, Anthony V. Moorman

Source: Genes, Chromosomes & Cancer; Aug2005, Vol. 43 Issue 4, p383-389, 7p

ETV6/RUNX1 fusion at diagnosis and relapse: Some prognostic indications.

Authors: Mary Martineau, G. Reza Jalali, Kerry E. Barber, Zo J. Broadfield, Kan Luk Cheung, John Lilleyman, Anthony V. Moorman, Sue Richards, Hazel M. Robinson, Fiona Ross, Christine J. Harrison

Source: Genes, Chromosomes & Cancer; May2005, Vol. 43 Issue 1, p54-71, 18p

Comparative expressed sequence hybridization studies of high‐hyperdiploid childhood acute lymphoblastic leukemia.

Authors: Alicja M. Gruszka‐Westwood, Sharon W. Horsley, Angel Martinez‐Ramirez, Christine J. Harrison, Helena Kempski, Anthony V. Moorman, Fiona M. Ross, Michael Griffiths, Mel F. Greaves, Lyndal Kearney

Source: Genes, Chromosomes & Cancer; Nov2004, Vol. 41 Issue 3, p191-202, 12p

MLL translocations with concurrent 3′ deletions: Interpretation of FISH results.

Authors: Kerry E. Barber, Anthony M. Ford, Rachel L. Harris, Christine J. Harrison, Anthony V. Moorman

Source: Genes, Chromosomes & Cancer; Nov2004, Vol. 41 Issue 3, p266-271, 6p

t(14;19)(q32;q13): A recurrent translocation in B-cell precursor acute lymphoblastic leukemia.

Authors: Hazel M. Robinson, Kerry E. Taylor, G. Reza Jalali, Kan Luk Cheung, Christine J. Harrison, Anthony V. Moorman

Source: Genes, Chromosomes & Cancer; Jan2004, Vol. 39 Issue 1, p88, 5p

Targeted treatment options for paediatric B-cell precursor acute lymphoblastic leukaemia patients with constitutional or somatic chromosome 21 alterations

Authors: Naomi Michels, Femke M. Hormann, Aurélie Boeree, Edwin Sonneveld, Anthony V. Moorman, Gabriele Escherich, Rosemary Sutton, H. Berna Beverloo, Rob Pieters, C. Michel Zwaan, Monique L. den Boer, Judith M. Boer

Source: EJC Paediatric Oncology, Vol 3, Iss , Pp 100140- (2024)

Subject Terms: Acute lymphoblastic leukemia, RAS, JAK, Paediatric, Chromosome 21, Down syndrome, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772610X23001381; https://doaj.org/toc/2772-610X

Access URL: https://doaj.org/article/ecb1e835fb504ce692dbd72007e10a05

Results from UKALL60+, a phase 2 study in older patients with untreated acute lymphoblastic leukemia

Authors: Bela Patel, Amy A. Kirkwood, Clare J. Rowntree, Krisztina Z. Alapi, Emilio Barretta, Laura Clifton‐Hadley, Tom Creasey, SooWah Lee, David I. Marks, Anthony V. Moorman, Nicholas Morley, Pip Patrick, Zaynab Rana, Anita Rijneveld, John A. Snowden, Adele K. Fielding

Source: HemaSphere, Vol 8, Iss 6, Pp n/a-n/a (2024)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/f8ed0d4f316040aaadab89e48c475ad0

Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia

Authors: Hayden L. Bell, Helen J. Blair, Mankaran Singh, Anthony V. Moorman, Olaf Heidenreich, Frederik W. van Delft, John Lunec, Julie A. E. Irving

Source: Cancer Cell International, Vol 23, Iss 1, Pp 1-14 (2023)

Subject Terms: WEE1, Inhibitors, Leukemia, High-risk, Relapse, Translational, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2867

Access URL: https://doaj.org/article/9deed2b8e0db4595931334af42559dac

The Prognostic Effect of IKZF1 Deletions in ETV6::RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

Authors: Anna Østergaard, Amir Enshaei, Rob Pieters, Ajay Vora, Martin A. Horstmann, Gabriele Escherich, Bertil Johansson, Mats Heyman, Kjeld Schmiegelow, Peter M. Hoogerbrugge, Monique L. den Boer, Roland P. Kuiper, Anthony V. Moorman, Judith M. Boer, Frank N. van Leeuwen

Source: HemaSphere, Vol 7, Iss 5, p e875 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000875; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/5645c5c18f97430d84ab7aaaba94a6bf

Clinical and Prognostic Impact of Copy Number Alterations and Associated Risk Profiles in a Cohort of Pediatric B-cell Precursor Acute Lymphoblastic Leukemia Cases Treated Under ICiCLe Protocol

Authors: Sanjeev Kumar Gupta, Minu Singh, Pragna H. Chandrashekar, Sameer Bakhshi, Amita Trehan, Ritu Gupta, Rozy Thakur, Smeeta Gajendra, Preity Sharma, Sreejesh Sreedharanunni, Manupdesh S. Sachdeva, Deepam Pushpam, Neelam Varma, Deepak Bansal, Richa Jain, Srinivasan Peyam, Anthony V. Moorman, Prateek Bhatia

Source: HemaSphere, Vol 6, Iss 10, p e782 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/HS9.0000000000000782; https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/b950bc5a01cc428cb83e1fab0526250c

Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement

Authors: Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. de Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell

Source: Haematologica, Vol 108, Iss 3 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10624; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/7ac03037b4cc476bb5a3d391aea80fe8

Genetic and genomic analysis of acute lymphoblastic leukemia in older adults reveals a distinct profile of abnormalities: analysis of 210 patients from the UKALL14 and UKALL60+ clinical trials

Authors: Thomas Creasey, Emilio Barretta, Sarra L. Ryan, Ellie Butler, Amy A. Kirkwood, Daniel Leongamornlert, Elli Papaemmanuil, Pip Patrick, Laura Clifton-Hadley, Bela Patel, Tobias Menne, Andrew K. McMillan, Christine J. Harrison, Clare J. Rowntree, Nick Morley, David I. Marks, Adele K. Fielding, Anthony V. Moorman

Source: Haematologica, Vol 107, Iss 9 (2021)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10453; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/8a04be27587840df8c9f2b5d4ebd7f27

The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment

Authors: Thai Hoa Tran, Jonathan V. Nguyen, Adrian Stecula, Jon Akutagawa, Anthony V. Moorman, Benjamin S. Braun, Andrej Sali, Charles G. Mullighan, Neil P. Shah, Yunfeng Dai, Meenakshi Devidas, Kathryn G. Roberts, Catherine C. Smith, Mignon L. Loh

Source: Haematologica, Vol 106, Iss 8 (2021)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10193; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/6b4cc17e613943ff9b4b6ed26ceaa218

Intragenic amplification of PAX5: a novel subgroup in B-cell precursor acute lymphoblastic leukemia?

Authors: Claire Schwab, Karin Nebral, Lucy Chilton, Cristina Leschi, Esmé Waanders, Judith M. Boer, Markéta Žaliová, Rosemary Sutton, Ingegerd Ivanov Öfverholm, Kentaro Ohki, Yuka Yamashita, Stefanie Groeneveld-Krentz, Eva Froňková, Marleen Bakkus, Joelle Tchinda, Thayana da Conceição Barbosa, Grazia Fazio, Wojciech Mlynarski, Agata Pastorczak, Giovanni Cazzaniga, Maria S. Pombo-de-Oliveira, Jan Trka, Renate Kirschner-Schwabe, Toshihiko Imamura, Gisela Barbany, Martin Stanulla, Andishe Attarbaschi, Renate Panzer-Grümayer, Roland P. Kuiper, Monique L. den Boer, Hélène Cavé, Anthony V. Moorman, Christine J. Harrison, Sabine Strehl

Source: Blood Advances, Vol 1, Iss 19, Pp 1473-1477 (2017)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2473952920302846; https://doaj.org/toc/2473-9529

Access URL: https://doaj.org/article/64841652a85648169d0a262aedd8c662

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Authors: Paul. B. Sinclair, Helen H. Blair, Sarra L. Ryan, Lars Buechler, Joanna Cheng, Jake Clayton, Rebecca Hanna, Shaun Hollern, Zoe Hawking, Matthew Bashton, Claire J. Schwab, Lisa Jones, Lisa J. Russell, Helen Marr, Peter Carey, Christina Halsey, Olaf Heidenreich, Anthony V. Moorman, Christine J. Harrison

Source: Haematologica, Vol 103, Iss 4 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8417; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/061b963a6e4f465eb098f328b26facdc