BAMLET kills chemotherapy-resistant mesothelioma cells, holding oleic acid in an activated cytotoxic state.

Authors: Emma M Rath, Yuen Yee Cheng, Mark Pinese, Kadir H Sarun, Amanda L Hudson, Christopher Weir, Yiwei D Wang, Anders P Håkansson, Viive M Howell, Guo Jun Liu, Glen Reid, Robert B Knott, Anthony P Duff, W Bret Church

Source: PLoS ONE, Vol 13, Iss 8, p e0203003 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC6114908?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b5148fcd6d5344b09e16fe05daeefe86

Binding and Dynamics Demonstrate the Destabilization of Ligand Binding for the S688Y Mutation in the NMDA Receptor GluN1 Subunit

Authors: Jake Zheng Chen, William Bret Church, Karine Bastard, Anthony P. Duff, Thomas Balle

Source: Molecules, Vol 28, Iss 10, p 4108 (2023)

Subject Terms: molecular dynamics, NMDA receptor, membrane protein, ligand binding, encephalopathies, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/10/4108; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/89e51df75ec846df9552c04bc57ec3c9

Structure and Potential Cellular Targets of HAMLET-like Anti-Cancer Compounds made from Milk Components

Authors: Emma M. Rath, Anthony P. Duff, Anders P. Håkansson, Catherine S. Vacher, Guo Jun Liu, Robert B. Knott, William Bret Church

Source: Journal of Pharmacy & Pharmaceutical Sciences, Vol 18, Iss 4 (2015)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/25205; https://doaj.org/toc/1482-1826

Access URL: https://doaj.org/article/cb9cc241d0344536b755f3108eefcede

Structural basis underlying the synergism of NADase and SLO during group A Streptococcus infection

Authors: Wei-Jiun Tsai, Yi-Hsin Lai, Yong-An Shi, Michal Hammel, Anthony P. Duff, Andrew E. Whitten, Karyn L. Wilde, Chun-Ming Wu, Robert Knott, U-Ser Jeng, Chia-Yu Kang, Chih-Yu Hsu, Jian-Li Wu, Pei-Jane Tsai, Chuan Chiang-Ni, Jiunn-Jong Wu, Yee-Shin Lin, Ching-Chuan Liu, Toshiya Senda, Shuying Wang

Source: Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/2cd8522dbd71452f8c5716972482d2f5

In-cell DNP NMR reveals multiple targeting effect of antimicrobial peptide

Authors: Frances Separovic, Vinzenz Hofferek, Anthony P. Duff, Malcom J. McConville, Marc-Antoine Sani

Source: Journal of Structural Biology: X, Vol 6, Iss , Pp 100074- (2022)

Subject Terms: Antimicrobial peptide, Bacteria, In-cell NMR, Membranes, DNP, REDOR, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590152422000150; https://doaj.org/toc/2590-1524

Access URL: https://doaj.org/article/62e986025a334d5ea341502dc782cb6d