CSF proteins of inflammation, proteolysis and lipid transport define preclinical AD and progression to AD dementia in cognitively unimpaired individuals

Authors: Marta del Campo, Carlos Quesada, Lisa Vermunt, Carel F. W. Peeters, Yanaika S. Hok-A-Hin, Calvin Trieu, Anouk den Braber, Inge M. W. Verberk, Pieter J. Visser, Betty M. Tijms, Wiesje M. van der Flier, Charlotte E. Teunissen

Source: Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-5 (2024)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1326

Access URL: https://doaj.org/article/02bf197ce2e0447abfb8c9d7bd7ba96c

Performance of plasma p‐tau217 and NfL in an unselected memory clinic setting

Authors: Rebecca Z. Rousset, Thomas Claessen, Argonde C. vanHarten, Afina W. Lemstra, Yolande A. L. Pijnenburg, Wiesje M. van derFlier, Anouk den Braber, Andreas Jeromin, Inge M. W. Verberk, Charlotte E. Teunissen

Source: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 4, Pp n/a-n/a (2024)

Subject Terms: AD continuum, Alzheimer's disease, biomarker profiles, blood‐based biomarkers, frontotemporal dementia, memory clinic, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8729

Access URL: https://doaj.org/article/f106dcd44d824a11815161c45552226d

Amyloid-PET imaging predicts functional decline in clinically normal individuals

Authors: Lisa Quenon, Lyduine E. Collij, David Vállez Garcia, Isadora Lopes Alves, Thomas Gérard, Vincent Malotaux, Lara Huyghe, Juan Domingo Gispert, Frank Jessen, Pieter Jelle Visser, Anouk den Braber, Craig W. Ritchie, Mercè Boada, Marta Marquié, Rik Vandenberghe, Emma S. Luckett, Michael Schöll, Giovanni B. Frisoni, Christopher Buckley, Andrew Stephens, Daniele Altomare, Lisa Ford, Cindy Birck, Anja Mett, Rossella Gismondi, Robin Wolz, Sylke Grootoonk, Richard Manber, Mahnaz Shekari, Renaud Lhommel, Laurence Dricot, Adrian Ivanoiu, Gill Farrar, Frederik Barkhof, Bernard J. Hanseeuw, the AMYPAD Consortium

Source: Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)

Subject Terms: Amyloid-PET, Centiloid, Preclinical Alzheimer, Functional decline, Instrumental activities of daily living, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1758-9193

Access URL: https://doaj.org/article/916789749e284220b7135dd30f36111c

Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer’s disease polygenic risk score

Authors: Jori Tomassen, Anouk den Braber, Sven J. van der Lee, Lianne M. Reus, Elles Konijnenberg, Stephen F. Carter, Maqsood Yaqub, Bart N.M. van Berckel, Lyduine E. Collij, Dorret I. Boomsma, Eco J.C. de Geus, Philip Scheltens, Karl Herholz, Betty M. Tijms, Pieter Jelle Visser

Source: BMC Neurology, Vol 22, Iss 1, Pp 1-11 (2022)

Subject Terms: Preclinical Alzheimer’s disease, APOE genotype, Polygenic risk score, Amyloid-β, Cognitive decline, Neuropsychology, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/de2470f34ab8427f961bab5f7eb68c5e

In vivo tau pathology is associated with synaptic loss and altered synaptic function

Authors: Emma M. Coomans, Deborah N. Schoonhoven, Hayel Tuncel, Sander C. J. Verfaillie, Emma E. Wolters, Ronald Boellaard, Rik Ossenkoppele, Anouk den Braber, Wiep Scheper, Patrick Schober, Steven P. Sweeney, J. Michael Ryan, Robert C. Schuit, Albert D. Windhorst, Frederik Barkhof, Philip Scheltens, Sandeep S. V. Golla, Arjan Hillebrand, Alida A. Gouw, Bart N. M. van Berckel

Source: Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2021)

Subject Terms: Alzheimer, Tau, Synaptic density, Synaptic function, PET, MEG, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1758-9193

Access URL: https://doaj.org/article/0311b602bb364b2b9a39d6b57ce39995

Ocular biomarkers for cognitive impairment in nonagenarians; a prospective cross-sectional study

Authors: Jacoba A. van de Kreeke, Nienke Legdeur, Maryam Badissi, H. Ton Nguyen, Elles Konijnenberg, Jori Tomassen, Mara ten Kate, Anouk den Braber, Andrea B. Maier, H. Stevie Tan, Frank D. Verbraak, Pieter Jelle Visser

Source: BMC Geriatrics, Vol 20, Iss 1, Pp 1-9 (2020)

Subject Terms: Retina, Optical coherence tomography, Fundus photography, Singapore I vessel assessment, Nonagenarians, Ocular biomarkers, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12877-020-01556-1; https://doaj.org/toc/1471-2318

Access URL: https://doaj.org/article/bd4c311aa7d14ea68c1d56f730da6465

Abnormal cerebrospinal fluid levels of amyloid and tau are associated with cognitive decline over time in cognitively normal older adults: A monozygotic twin study

Authors: Jori Tomassen, Anouk den Braber, Sophie M. van der Landen, Elles Konijnenberg, Charlotte E. Teunissen, Lisa Vermunt, Eco J. C. de Geus, Dorret I. Boomsma, Philip Scheltens, Betty M. Tijms, Pieter Jelle Visser

Source: Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)

Subject Terms: amyloid‐beta, biomarkers, cerebrospinal fluid, cognition, cognitive decline, longitudinal design, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8737

Access URL: https://doaj.org/article/277af6272e3a491a827c46fdb6ccb8f0

Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

Authors: Fiona A. Hagenbeek, René Pool, Jenny van Dongen, Harmen H. M. Draisma, Jouke Jan Hottenga, Gonneke Willemsen, Abdel Abdellaoui, Iryna O. Fedko, Anouk den Braber, Pieter Jelle Visser, Eco J. C. N. de Geus, Ko Willems van Dijk, Aswin Verhoeven, H. Eka Suchiman, Marian Beekman, P. Eline Slagboom, Cornelia M. van Duijn, BBMRI Metabolomics Consortium, Amy C. Harms, Thomas Hankemeier, Meike Bartels, Michel G. Nivard, Dorret I. Boomsma

Source: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/bdd7a85c5d32461f9a054623f04904bd

White matter microstructure disruption in early stage amyloid pathology

Authors: Lyduine E. Collij, Silvia Ingala, Herwin Top, Viktor Wottschel, Kristine E. Stickney, Jori Tomassen, Elles Konijnenberg, Mara ten Kate, Carole Sudre, Isadora Lopes Alves, Maqsood M. Yaqub, Alle Meije Wink, Dennis Van ‘t Ent, Philip Scheltens, Bart N.M. vanBerckel, Pieter Jelle Visser, Frederik Barkhof, Anouk Den Braber

Source: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)

Subject Terms: Amyloid beta (Aβ), diffusion tensor imaging (DTI), magnetic resonance imaging (MRI), positron emission tomography (PET), preclinical Alzheimer's disease (AD), white matter microstructure, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8729

Access URL: https://doaj.org/article/c4b13b8a0c6a4a42b7af36d1b23cafda

The EMIF-AD PreclinAD study: study design and baseline cohort overview

Authors: Elles Konijnenberg, Stephen F. Carter, Mara ten Kate, Anouk den Braber, Jori Tomassen, Chinenye Amadi, Linda Wesselman, Hoang-Ton Nguyen, Jacoba A. van de Kreeke, Maqsood Yaqub, Matteo Demuru, Sandra D. Mulder, Arjan Hillebrand, Femke H. Bouwman, Charlotte E. Teunissen, Erik H. Serné, Annette C. Moll, Frank D. Verbraak, Rainer Hinz, Neil Pendleton, Adriaan A. Lammertsma, Bart N. M. van Berckel, Frederik Barkhof, Dorret I. Boomsma, Philip Scheltens, Karl Herholz, Pieter Jelle Visser

Source: Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-12 (2018)

Subject Terms: Preclinical Alzheimer’s disease, Amyloid, Cognitively normal, Monozygotic twins, [18F]flutemetamol, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13195-018-0406-7; https://doaj.org/toc/1758-9193

Access URL: https://doaj.org/article/1550fd3ad24a4070bf47c772e48b117e

Novel genetic loci associated with hippocampal volume

Authors: Derrek P. Hibar, Hieab H. H. Adams, Neda Jahanshad, Ganesh Chauhan, Jason L. Stein, Edith Hofer, Miguel E. Renteria, Joshua C. Bis, Alejandro Arias-Vasquez, M. Kamran Ikram, Sylvane Desrivières, Meike W. Vernooij, Lucija Abramovic, Saud Alhusaini, Najaf Amin, Micael Andersson, Konstantinos Arfanakis, Benjamin S. Aribisala, Nicola J. Armstrong, Lavinia Athanasiu, Tomas Axelsson, Ashley H. Beecham, Alexa Beiser, Manon Bernard, Susan H. Blanton, Marc M. Bohlken, Marco P. Boks, Janita Bralten, Adam M. Brickman, Owen Carmichael, M. Mallar Chakravarty, Qiang Chen, Christopher R. K. Ching, Vincent Chouraki, Gabriel Cuellar-Partida, Fabrice Crivello, Anouk Den Braber, Nhat Trung Doan, Stefan Ehrlich, Sudheer Giddaluru, Aaron L. Goldman, Rebecca F. Gottesman, Oliver Grimm, Michael E. Griswold, Tulio Guadalupe, Boris A. Gutman, Johanna Hass, Unn K. Haukvik, David Hoehn, Avram J. Holmes, Martine Hoogman, Deborah Janowitz, Tianye Jia, Kjetil N. Jørgensen, Nazanin Karbalai, Dalia Kasperaviciute, Sungeun Kim, Marieke Klein, Bernd Kraemer, Phil H. Lee, David C. M. Liewald, Lorna M. Lopez, Michelle Luciano, Christine Macare, Andre F. Marquand, Mar Matarin, Karen A. Mather, Manuel Mattheisen, David R. McKay, Yuri Milaneschi, Susana Muñoz Maniega, Kwangsik Nho, Allison C. Nugent, Paul Nyquist, Loes M. Olde Loohuis, Jaap Oosterlaan, Martina Papmeyer, Lukas Pirpamer, Benno Pütz, Adaikalavan Ramasamy, Jennifer S. Richards, Shannon L. Risacher, Roberto Roiz-Santiañez, Nanda Rommelse, Stefan Ropele, Emma J. Rose, Natalie A. Royle, Tatjana Rundek, Philipp G. Sämann, Arvin Saremi, Claudia L. Satizabal, Lianne Schmaal, Andrew J. Schork, Li Shen, Jean Shin, Elena Shumskaya, Albert V. Smith, Emma Sprooten, Lachlan T. Strike, Alexander Teumer, Diana Tordesillas-Gutierrez, Roberto Toro, Daniah Trabzuni, Stella Trompet, Dhananjay Vaidya, Jeroen Van der Grond, Sven J. Van der Lee, Dennis Van der Meer, Marjolein M. J. Van Donkelaar, Kristel R. Van Eijk, Theo G. M. Van Erp, Daan Van Rooij, Esther Walton, Lars T. Westlye, Christopher D. Whelan, Beverly G. Windham, Anderson M. Winkler, Katharina Wittfeld, Girma Woldehawariat, Christiane Wolf, Thomas Wolfers, Lisa R. Yanek, Jingyun Yang, Alex Zijdenbos, Marcel P. Zwiers, Ingrid Agartz, Laura Almasy, David Ames, Philippe Amouyel, Ole A. Andreassen, Sampath Arepalli, Amelia A. Assareh, Sandra Barral, Mark E. Bastin, Diane M. Becker, James T. Becker, David A. Bennett, John Blangero, Hans van Bokhoven, Dorret I. Boomsma, Henry Brodaty, Rachel M. Brouwer, Han G. Brunner, Randy L. Buckner, Jan K. Buitelaar, Kazima B. Bulayeva, Wiepke Cahn, Vince D. Calhoun, Dara M. Cannon, Gianpiero L. Cavalleri, Ching-Yu Cheng, Sven Cichon, Mark R. Cookson, Aiden Corvin, Benedicto Crespo-Facorro, Joanne E. Curran, Michael Czisch, Anders M. Dale, Gareth E. Davies, Anton J. M. De Craen, Eco J. C. De Geus, Philip L. De Jager, Greig I. De Zubicaray, Ian J. Deary, Stéphanie Debette, Charles DeCarli, Norman Delanty, Chantal Depondt, Anita DeStefano, Allissa Dillman, Srdjan Djurovic, Gary Donohoe, Wayne C. Drevets, Ravi Duggirala, Thomas D. Dyer, Christian Enzinger, Susanne Erk, Thomas Espeseth, Iryna O. Fedko, Guillén Fernández, Luigi Ferrucci, Simon E. Fisher, Debra A. Fleischman, Ian Ford, Myriam Fornage, Tatiana M. Foroud, Peter T. Fox, Clyde Francks, Masaki Fukunaga, J. Raphael Gibbs, David C. Glahn, Randy L. Gollub, Harald H. H. Göring, Robert C. Green, Oliver Gruber, Vilmundur Gudnason, Sebastian Guelfi, Asta K. Håberg, Narelle K. Hansell, John Hardy, Catharina A. Hartman, Ryota Hashimoto, Katrin Hegenscheid, Andreas Heinz, Stephanie Le Hellard, Dena G. Hernandez, Dirk J. Heslenfeld, Beng-Choon Ho, Pieter J. Hoekstra, Wolfgang Hoffmann, Albert Hofman, Florian Holsboer, Georg Homuth, Norbert Hosten, Jouke-Jan Hottenga, Matthew Huentelman, Hilleke E. Hulshoff Pol, Masashi Ikeda, Clifford R. Jack Jr, Mark Jenkinson, Robert Johnson, Erik G. Jönsson, J. Wouter Jukema, René S. Kahn, Ryota Kanai, Iwona Kloszewska, David S. Knopman, Peter Kochunov, John B. Kwok, Stephen M. Lawrie, Hervé Lemaître, Xinmin Liu, Dan L. Longo, Oscar L. Lopez, Simon Lovestone, Oliver Martinez, Jean-Luc Martinot, Venkata S. Mattay, Colm McDonald, Andrew M. McIntosh, Francis J. McMahon, Katie L. McMahon, Patrizia Mecocci, Ingrid Melle, Andreas Meyer-Lindenberg, Sebastian Mohnke, Grant W. Montgomery, Derek W. Morris, Thomas H. Mosley, Thomas W. Mühleisen, Bertram Müller-Myhsok, Michael A. Nalls, Matthias Nauck, Thomas E. Nichols, Wiro J. Niessen, Markus M. Nöthen, Lars Nyberg, Kazutaka Ohi, Rene L. Olvera, Roel A. Ophoff, Massimo Pandolfo, Tomas Paus, Zdenka Pausova, Brenda W. J. H. Penninx, G. Bruce Pike, Steven G. Potkin, Bruce M. Psaty, Simone Reppermund, Marcella Rietschel, Joshua L. Roffman, Nina Romanczuk-Seiferth, Jerome I. Rotter, Mina Ryten, Ralph L. Sacco, Perminder S. Sachdev, Andrew J. Saykin, Reinhold Schmidt, Helena Schmidt, Peter R. Schofield, Sigurdur Sigursson, Andrew Simmons, Andrew Singleton, Sanjay M. Sisodiya, Colin Smith, Jordan W. Smoller, Hilkka Soininen, Vidar M. Steen, David J. Stott, Jessika E. Sussmann, Anbupalam Thalamuthu, Arthur W. Toga, Bryan J. Traynor, Juan Troncoso, Magda Tsolaki, Christophe Tzourio, Andre G. Uitterlinden, Maria C. Valdés Hernández, Marcel Van der Brug, Aad van der Lugt, Nic J. A. van der Wee, Neeltje E. M. Van Haren, Dennis van ’t Ent, Marie-Jose Van Tol, Badri N. Vardarajan, Bruno Vellas, Dick J. Veltman, Henry Völzke, Henrik Walter, Joanna M. Wardlaw, Thomas H. Wassink, Michael E. Weale, Daniel R. Weinberger, Michael W. Weiner, Wei Wen, Eric Westman, Tonya White, Tien Y. Wong, Clinton B. Wright, Ronald H. Zielke, Alan B. Zonderman, Nicholas G. Martin, Cornelia M. Van Duijn, Margaret J. Wright, W. T. Longstreth, Gunter Schumann, Hans J. Grabe, Barbara Franke, Lenore J. Launer, Sarah E. Medland, Sudha Seshadri, Paul M. Thompson, M. Arfan Ikram

Source: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/769accb8151a4aceadb44ac82c3f59e0

Homogenizing Estimates of Heritability Among SOLAR-Eclipse, OpenMx, APACE, and FPHI Software Packages in Neuroimaging Data

Authors: Peter Kochunov, Binish Patel, Habib Ganjgahi, Brian Donohue, Meghann Ryan, Elliot L. Hong, Xu Chen, Bhim Adhikari, Neda Jahanshad, Paul M. Thompson, Dennis Van’t Ent, Anouk den Braber, Eco J. C. de Geus, Rachel M. Brouwer, Dorret I. Boomsma, Hilleke E. Hulshoff Pol, Greig I. de Zubicaray, Katie L. McMahon, Nicholas G. Martin, Margaret J. Wright, Thomas E. Nichols

Source: Frontiers in Neuroinformatics, Vol 13 (2019)

Subject Terms: DTI, heritability, imaging genetics, reproducability, genetics, population, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fninf.2019.00016/full; https://doaj.org/toc/1662-5196

Access URL: https://doaj.org/article/33ad280a795e4913b39dbec284ea8718

Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data

Authors: Isabelle Bos, Stephanie J. B. Vos, Willemijn J. Jansen, Rik Vandenberghe, Silvy Gabel, Ainara Estanga, Mirian Ecay-Torres, Jori Tomassen, Anouk den Braber, Alberto Lleó, Isabel Sala, Anders Wallin, Petronella Kettunen, José L. Molinuevo, Lorena Rami, Gaël Chetelat, Vincent de la Sayette, Magda Tsolaki, Yvonne Freund-Levi, Peter Johannsen, The Alzheimer's Disease Neuroimaging Initiative, Gerald P. Novak, Inez Ramakers, Frans R. Verhey, Pieter Jelle Visser

Source: Frontiers in Aging Neuroscience, Vol 10 (2018)

Subject Terms: Alzheimer's disease, amyloid-beta, tau, cognition, neuropsychological examination, normative data, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnagi.2018.00193/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/7d99b5ef6ae14298a061444872adece3

Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies

Authors: Fiona A. Hagenbeek, René Pool, Jenny van Dongen, H. M. Draisma, Jouke Jan Hottenga, Gonneke Willemsen, Abdel Abdellaoui, Iryna O. Fedko, Anouk den Braber, Pieter Jelle Visser, Eco J. C. N. de Geus, Ko Willems van Dijk, Aswin Verhoeven, H. Eka Suchiman, Marian Beekman, P. Eline Slagboom, Cornelia M. van Duijn, BBMRI Metabolomics Consortium, Amy C. Harms, Thomas Hankemeier, Meike Bartels, Michel G. Nivard, Dorret I. Boomsma

Source: Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b65681b22d914170b8fba0c5f5e1d1c4

Resting-State fMRI Functional Connectivity Is Associated with Sleepiness, Imagery, and Discontinuity of Mind.

Authors: Diederick Stoffers, B Alexander Diaz, Gang Chen, Anouk den Braber, Dennis van 't Ent, Dorret I Boomsma, Huibert D Mansvelder, Eco de Geus, Eus J W Van Someren, Klaus Linkenkaer-Hansen

Source: PLoS ONE, Vol 10, Iss 11, p e0142014 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4634926?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ebb52647669847299b97df1007959112

Sex differences in gray and white matter structure in age-matched unrelated males and females and opposite-sex siblings.

Authors: Anouk den Braber, Dennis van ‘t Ent, Diederick Stoffers, Klaus Linkenkaer-Hansen, Dorret I. Boomsma, Eco J.C. de Geus

Source: International Journal of Psychological Research, Vol 6 (2013)

Subject Terms: Sex differences, opposite-sex twins, structural magnetic resonance imaging, voxel based morphometry, diffusion tensor imaging, fractional anisotropy., Psychology, BF1-990

File Description: electronic resource

Relation: https://revistas.usb.edu.co/index.php/IJPR/article/view/712; https://doaj.org/toc/2011-2084; https://doaj.org/toc/2011-7922

Access URL: https://doaj.org/article/3a233cccd6fe4cd4b9d2c73401f143c0

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