Regulation of nc886 (vtRNA2-1) RNAs is associated with cardiometabolic risk factors and diseases

Authors: Sonja Rajić, Thomas Delerue, Justiina Ronkainen, Ruiyuan Zhang, Joanna Ciantar, Daria Kostiniuk, Pashupati P. Mishra, Leo-Pekka Lyytikäinen, Nina Mononen, Laura Kananen, Annette Peters, Juliane Winkelmann, Marcus E. Kleber, Stefan Lorkowski, Mika Kähönen, Terho Lehtimäki, Olli Raitakari, Melanie Waldenberger, Christian Gieger, Winfried März, Emily W. Harville, Sylvain Sebert, Saara Marttila, Emma Raitoharju

Source: Clinical Epigenetics, Vol 17, Iss 1, Pp 1-15 (2025)

Subject Terms: nc886, Cardiometabolic disease, Imprinted gene, DNA methylation, vtRNA2-1, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/f0630794563c4715b70bcc22704edcd7

Cross-sectional and longitudinal association of seven DNAm-based predictors with metabolic syndrome and type 2 diabetes

Authors: Suet Mei Chew, Alexander Teumer, Pamela R. Matías‑García, Christian Gieger, Juliane Winckelmann, Karsten Suhre, Christian Herder, Wolfgang Rathmann, Annette Peters, Melanie Waldenberger

Source: Clinical Epigenetics, Vol 17, Iss 1, Pp 1-16 (2025)

Subject Terms: Epigenetic age acceleration, DNAm age, Metabolic syndrome, Diabetes, Risk prediction, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/28bd913497d54befbd04f0aa3fa521bc

LEOPARD: missing view completion for multi-timepoint omics data via representation disentanglement and temporal knowledge transfer

Authors: Siyu Han, Shixiang Yu, Mengya Shi, Makoto Harada, Jianhong Ge, Jiesheng Lin, Cornelia Prehn, Agnese Petrera, Ying Li, Flora Sam, Giuseppe Matullo, Jerzy Adamski, Karsten Suhre, Christian Gieger, Stefanie M. Hauck, Christian Herder, Michael Roden, Francesco Paolo Casale, Na Cai, Annette Peters, Rui Wang-Sattler

Source: Nature Communications, Vol 16, Iss 1, Pp 1-20 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e4e92326b3bf41d6a466f35ae89242a9

Individual bioenergetic capacity as a potential source of resilience to Alzheimer’s disease

Authors: Matthias Arnold, Mustafa Buyukozkan, P. Murali Doraiswamy, Kwangsik Nho, Tong Wu, Vilmundur Gudnason, Lenore J. Launer, Rui Wang-Sattler, Jerzy Adamski, The Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Metabolomics Consortium, Philip L. De Jager, Nilüfer Ertekin-Taner, David A. Bennett, Andrew J. Saykin, Annette Peters, Karsten Suhre, Rima Kaddurah-Daouk, Gabi Kastenmüller, Jan Krumsiek

Source: Nature Communications, Vol 16, Iss 1, Pp 1-15 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/193737912505468d849ea8fa121a4645

Phenotype-based clusters, inflammation and cardiometabolic complications in older people before the diagnosis of type 2 diabetes: KORA F4/FF4 cohort study

Authors: Marie-Theres Huemer, Maria C. Spagnuolo, Haifa Maalmi, Robert Wagner, Gidon J. Bönhof, Margit Heier, Wolfgang Koenig, Wolfgang Rathmann, Katsiaryna Prystupa, Jana Nano, Dan Ziegler, Annette Peters, Michael Roden, Barbara Thorand, Christian Herder

Source: Cardiovascular Diabetology, Vol 24, Iss 1, Pp 1-14 (2025)

Subject Terms: Cardiovascular disease, Chronic kidney disease, Cohort, Diabetes, Heterogeneity, Inflammation, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/a51e8bed23c9491c82616ddca4df04fe

Longitudinal association between DNA methylation and type 2 diabetes: findings from the KORA F4/FF4 study

Authors: Liye Lai, Dave Laurence Juntilla, Monica Del, Monica Del C Gomez-Alonso, Harald Grallert, Barbara Thorand, Aiman Farzeen, Wolfgang Rathmann, Juliane Winkelmann, Holger Prokisch, Christian Gieger, Christian Herder, Annette Peters, Melanie Waldenberger

Source: Cardiovascular Diabetology, Vol 24, Iss 1, Pp 1-15 (2025)

Subject Terms: DNA methylation, Type 2 diabetes, Glycemic traits, Diabetes progression, Gene expression, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/8b525027daa34619a39bf19bc69da5a0

Deceleration capacity derived from a five-minute electrocardiogram predicts mortality in the general population

Authors: Alexander Steger, Petra Barthel, Alexander Müller, Ina-Maria Rückert-Eheberg, Birgit Linkohr, Julia Allescher, Melanie Maier, Alexander Hapfelmeier, Eimo Martens, Helene Hildegard Heidegger, Arne Michael Müller, Konstantinos D. Rizas, Stefan Kääb, Moritz F. Sinner, Daniel Sinnecker, Karl-Ludwig Laugwitz, Annette Peters, Georg Schmidt

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)

Subject Terms: General population screening, Non-invasive long-term risk stratification, Fully automated biosignal analysis, Electrocardiogram, Deceleration capacity of the heart rate, Autonomic regulation, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/b1e629972d4a4ea6be103e7f6751741a

Interpretable multimodal machine learning (IMML) framework reveals pathological signatures of distal sensorimotor polyneuropathy

Authors: Phong B. H. Nguyen, Daniel Garger, Diyuan Lu, Haifa Maalmi, Holger Prokisch, Barbara Thorand, Jerzy Adamski, Gabi Kastenmüller, Melanie Waldenberger, Christian Gieger, Annette Peters, Karsten Suhre, Gidon J. Bönhof, Wolfgang Rathmann, Michael Roden, Harald Grallert, Dan Ziegler, Christian Herder, Michael P. Menden

Source: Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2730-664X

Access URL: https://doaj.org/article/5acfc6a920e74f95b20e962048f193f5

Novel loci and biomedical consequences of iron homoeostasis variation

Authors: Elias Allara, Steven Bell, Rebecca Smith, Spencer J. Keene, Dipender Gill, Liam Gaziano, Deisy Morselli Gysi, Feiyi Wang, Vinicius Tragante, Amy Mason, Savita Karthikeyan, R. Thomas Lumbers, Emmanuela Bonglack, Willem Ouwehand, David J. Roberts, Joseph Dowsett, Sisse Rye Ostrowski, Margit Hørup Larsen, Henrik Ullum, Ole Birger Pedersen, Søren Brunak, Karina Banasik, Christian Erikstrup, DBDS Genomic Consortium, Jonathan Mitchell, Christian Fuchsberger, Cristian Pattaro, Peter P. Pramstaller, Domenico Girelli, Mikko Arvas, Jarkko Toivonen, Sophie Molnos, Annette Peters, Ozren Polasek, Igor Rudan, Caroline Hayward, Ciara McDonnell, Nicola Pirastu, James F. Wilson, Katja van den Hurk, Franke Quee, Luigi Ferrucci, Stefania Bandinelli, Toshiko Tanaka, Giorgia Girotto, Maria Pina Concas, Alessandro Pecori, Niek Verweij, Pim van der Harst, Yordi J. van de Vegte, Lambertus A. Kiemeney, Fred C. Sweep, Tessel E. Galesloot, Patrick Sulem, Daniel Gudbjartsson, Egil Ferkingstad, FinnGen Consortium, Luc Djousse, Kelly Cho, Michael Inouye, Stephen Burgess, Beben Benyamin, Konrad Oexle, Dorine Swinkels, Kari Stefansson, Magnus Magnusson, Andrea Ganna, Michael Gaziano, Kerry Ivey, John Danesh, Alexandre Pereira, Angela M. Wood, Adam S. Butterworth, Emanuele Di Angelantonio

Source: Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/9612bd28250149b99e442728bc5f20bf

Sex Differences in the Relationship of Socioeconomic Position With Cardiovascular Disease, Cardiovascular Risk Factors, and Estimated Cardiovascular Disease Risk: Results of the German National Cohort

Authors: Ilais Moreno Velásquez, Sanne A. E. Peters, Nico Dragano, Karin Halina Greiser, Marcus Dörr, Beate Fischer, Klaus Berger, Anke Hannemann, Renate B. Schnabel, Matthias Nauck, Susanne Göttlicher, Susanne Rospleszcz, Stefan N. Willich, Lilian Krist, Matthias B. Schulze, Kathrin Günther, Tilman Brand, Tamara Schikowski, Carina Emmel, Börge Schmidt, Karin B. Michels, Rafael Mikolajczyk, Alexander Kluttig, Volker Harth, Nadia Obi, Stefanie Castell, Carolina J. Klett‐Tammen, Wolfgang Lieb, Heiko Becher, Volker Winkler, Heike Minnerup, André Karch, Claudia Meinke‐Franze, Michael Leitzmann, Michael J. Stein, Barbara Bohn, Ben Schöttker, Kira Trares, Annette Peters, Tobias Pischon

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 14, Iss 5 (2025)

Subject Terms: cardiovascular disease, cardiovascular risk, educational attainment, income, socioeconomic position, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/4203b8dda9454afe80bcd928771b675a

Mendelian randomization study highlights the role of hematological traits on Type-2 diabetes mellitus in African ancestry individuals

Authors: Chisom Soremekun, Daudi Jjingo, David Kateete, Oyekanmi Nash, Dorothea Nitsch, Moffat Nyirenda, Dipender Gill, Eleftheria Zeggini, Harald Grallert, Annette Peters, Tinashe Chikowore, Chiara Batini, Opeyemi Soremekun, Segun Fatumo

Source: Frontiers in Pharmacology, Vol 16 (2025)

Subject Terms: Type-2 diabetes, blood cell traits, mendelian randomization, Africa, Hematological traits, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2025.1436972/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/8848ef2157fa4890b0d598fc59612ea0

The mediatory role of androgens on sex differences in glucose homeostasis and incidence of type 2 diabetes: the KORA study

Authors: Hamidreza Raeisi-Dehkordi, Barbara Thorand, Sara Beigrezaei, Annette Peters, Wolfgang Rathman, Jerzy Adamski, Angeline Chatelan, Yvonne T. van der Schouw, Oscar H. Franco, Taulant Muka, Jana Nano

Source: Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-11 (2024)

Subject Terms: Sex differences, Sex hormones, Androgens, Glycemic control, Type 2 diabetes, Mediation analysis., Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/924b8285d5314ae8a5c24bde2da692fd

Atmospheric new particle formation identifier using longitudinal global particle number size distribution data

Authors: Simonas Kecorius, Leizel Madueño, Mario Lovric, Nikolina Racic, Maximilian Schwarz, Josef Cyrys, Juan Andrés Casquero-Vera, Lucas Alados-Arboledas, Sébastien Conil, Jean Sciare, Jakub Ondracek, Anna Gannet Hallar, Francisco J. Gómez-Moreno, Raymond Ellul, Adam Kristensson, Mar Sorribas, Nikolaos Kalivitis, Nikolaos Mihalopoulos, Annette Peters, Maria Gini, Konstantinos Eleftheriadis, Stergios Vratolis, Kim Jeongeun, Wolfram Birmili, Benjamin Bergmans, Nina Nikolova, Adelaide Dinoi, Daniele Contini, Angela Marinoni, Andres Alastuey, Tuukka Petäjä, Sergio Rodriguez, David Picard, Benjamin Brem, Max Priestman, David C. Green, David C. S. Beddows, Roy M. Harrison, Colin O’Dowd, Darius Ceburnis, Antti Hyvärinen, Bas Henzing, Suzanne Crumeyrolle, Jean-Philippe Putaud, Paolo Laj, Kay Weinhold, Kristina Plauškaitė, Steigvilė Byčenkienė

Source: Scientific Data, Vol 11, Iss 1, Pp 1-10 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2052-4463

Access URL: https://doaj.org/article/9b3c536832eb4a779fe51832dbc05a02

Association between myosteatosis and impaired glucose metabolism: A deep learning whole‐body magnetic resonance imaging population phenotyping approach

Authors: Matthias Jung, Hanna Rieder, Marco Reisert, Susanne Rospleszcz, Johanna Nattenmueller, Annette Peters, Christopher L. Schlett, Fabian Bamberg, Jakob Weiss

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 5, Pp 1750-1760 (2024)

Subject Terms: body composition, diabetes, myosteatosis, quantitative MRI, skeletal muscle, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/00123a66db364f46a6e19dab14331fcc

Association analysis between an epigenetic alcohol risk score and blood pressure

Authors: Helena Bui, Amena Keshawarz, Mengyao Wang, Mikyeong Lee, Scott M. Ratliff, Lisha Lin, Kira S. Birditt, Jessica D. Faul, Annette Peters, Christian Gieger, Thomas Delerue, Sharon L. R. Kardia, Wei Zhao, Xiuqing Guo, Jie Yao, Jerome I. Rotter, Yi Li, Xue Liu, Dan Liu, Juliana F. Tavares, Gökhan Pehlivan, Monique M. B. Breteler, Irma Karabegovic, Carolina Ochoa-Rosales, Trudy Voortman, Mohsen Ghanbari, Joyce B. J. van Meurs, Mohamed Kamal Nasr, Marcus Dörr, Hans J. Grabe, Stephanie J. London, Alexander Teumer, Melanie Waldenberger, David R. Weir, Jennifer A. Smith, Daniel Levy, Jiantao Ma, Chunyu Liu

Source: Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)

Subject Terms: Epigenetic risk score, DNA methylation, Blood pressure, Hypertension, Alcohol, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/778cf18febfb469f98f4928da01f6554

Subclinical impairment of the left atrium is associated with MRI-based lung volume but not with parameters from pulmonary function testing

Authors: Charlotte Wintergerst, Roberto Lorbeer, Blerim Mujaj, Bernard E. Bulwer, Susanne Rospleszcz, Esther Askani, Holger Schulz, Stefan Karrasch, Annette Peters, Christopher L. Schlett, Fabian Bamberg, Ricarda von Krüchten

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)

Subject Terms: Population-based whole-body MRI, Subclinical cardiopulmonary impairment, Heart failure with preserved ejection fraction, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/aea96e769c554202a7e2cbb799f104dd

Association of plasma proteomics with mortality in individuals with and without type 2 diabetes: Results from two population-based KORA cohort studies

Authors: Hong Luo, Agnese Petrera, Stefanie M. Hauck, Wolfgang Rathmann, Christian Herder, Christian Gieger, Annika Hoyer, Annette Peters, Barbara Thorand

Source: BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)

Subject Terms: Proteomics, All-cause mortality, Type 2 diabetes, Cardiovascular mortality, Cancer-related mortality, Other-cause mortality, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/b7fb32982f614d9383d286e2f1c76ab3

Lung function-associated exposome profile in the era of climate change: Pooled analysis of 8 population-based European cohorts within the EXPANSE project

Authors: Ayoung Jeong, Gianfranco Lovison, Alonso Bussalleu, Marta Cirach, Payam Dadvand, Kees de Hoogh, Claudia Flexeder, Gerard Hoek, Medea Imboden, Stefan Karrasch, Gerard H. Koppelman, Sara Kress, Petter Ljungman, Renata Majewska, Göran Pershagen, Regina Pickford, Youchen Shen, Roel C.H. Vermeulen, Jelle J. Vlaanderen, Megi Vogli, Kathrin Wolf, Zhebin Yu, Erik Melén, Agnieszka Pac, Annette Peters, Tamara Schikowski, Marie Standl, Ulrike Gehring, Nicole Probst-Hensch

Source: Environment International, Vol 196, Iss , Pp 109269- (2025)

Subject Terms: Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0160412025000200; https://doaj.org/toc/0160-4120

Access URL: https://doaj.org/article/2ff28fa40d61495880327370d823505a

Cardiovascular disease outcomes in relation to 25-hydroxyvitamin D and its seasonal variation: Results from the BiomarCaRE consortium.

Authors: Viktor Oskarsson, Veikko Salomaa, Pekka Jousilahti, Luigi Palmieri, Chiara Donfrancesco, Susana Sans, Licia Iacoviello, Simona Costanzo, Marco M Ferrario, Giancarlo Cesana, Barbara Thorand, Annette Peters, Hugh Tunstall-Pedoe, Mark Woodward, Tanja Zeller, Stefan Blankenberg, Kari Kuulasmaa, Stefan Söderberg

Source: PLoS ONE, Vol 20, Iss 4, p e0319607 (2025)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6d0ff4cd02cd44bcbb309f00ac3cac7d

Respiratory rate and its associations with disease and lifestyle factors in the general population – results from the KORA-FF4 study

Authors: Ina-Maria Rückert-Eheberg, Alexander Steger, Alexander Müller, Birgit Linkohr, Petra Barthel, Melanie Maier, Julia Allescher, Moritz F. Sinner, Konstantinos D. Rizas, Wolfgang Rathmann, Karl-Ludwig Laugwitz, Stefan Kääb, Annette Peters, Georg Schmidt

Source: PLoS ONE, Vol 20, Iss 3 (2025)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11896064/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/abc1fa7cf16b4fd19c276c913c5a9721