CRISPR/Cas9-edited ROS1 + non-small cell lung cancer cell lines highlight differential drug sensitivity in 2D vs 3D cultures while reflecting established resistance profiles

Authors: Marc Terrones, Christophe Deben, Felicia Rodrigues-Fortes, Anne Schepers, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)

Subject Terms: ROS1 + Non-small cell lung cancer, Tyrosine kinase inhibitors, CRISPR/Cas9, Drug resistance, 3D cell culture, 2D cell culture, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/8badfa4b346b46089af6735007b9b043

Epigenome-wide methylation analysis of colorectal carcinoma, adenoma and normal tissue reveals novel biomarkers addressing unmet clinical needs

Authors: Katleen Janssens, Isabelle Neefs, Joe Ibrahim, Anne Schepers, Patrick Pauwels, Marc Peeters, Guy Van Camp, Ken Op de Beeck

Source: Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)

Subject Terms: Colorectal cancer, Methylation, Biomarkers, Adenoma, Carcinoma, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/f0195dd157dc48ceb7a73e17eb3bb1f3