Practical Utility of Serum Ammonia in Children With Acute Liver Failure: A Biomarker of Outcome

Authors: Hala Mohsen Abdullatif, MD, Katharina Weigel, Anita Verma, MD, Akash Deep, MD, Anil Dhawan, MD, FRCPCH

Source: Transplantation Direct, Vol 11, Iss 3, p e1755 (2025)

Subject Terms: Surgery, RD1-811

File Description: electronic resource

Relation: http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001755; https://doaj.org/toc/2373-8731

Access URL: https://doaj.org/article/024fc774f89e46f19f3233ab91d95571

Hereditary tyrosinaemia type 1 in the absence of succinylacetone: 4‐oxo 6‐hydroxyhepanoate (4OHHA), a putative diagnostic biomarker

Authors: Preeya Rehsi, Karolina Witek, Erin Emmett, Rachel Carling, Charles Turner, Neil Dalton, Tim Hutchin, Nedim Hadzic, Anil Dhawan, Roshni Vara

Source: JIMD Reports, Vol 65, Iss 4, Pp 255-261 (2024)

Subject Terms: 4‐oxo 6‐hydroxyhepanoate, emerging diagnostic biomarker, fumarylacetoacetate hydrolase, succinylacetone, tyrosinaemia type 1, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2192-8312

Access URL: https://doaj.org/article/e08df0a789ed4de9ad5e32b318cf89af

Liver transplantation in ornithine transcarbamylase deficiency: A retrospective multicentre cohort study

Authors: Berna Seker Yilmaz, Julien Baruteau, Anupam Chakrapani, Michael Champion, Efstathia Chronopoulou, Lee C. Claridge, Anne Daly, Catherine Davies, James Davison, Anil Dhawan, Stephanie Grunewald, Girish L. Gupte, Nigel Heaton, Hugh Lemonde, Pat McKiernan, Philippa Mills, Andrew A.M. Morris, Helen Mundy, Germaine Pierre, Sanjay Rajwal, Siyamini Sivananthan, Srividya Sreekantam, Karolina M. Stepien, Roshni Vara, Mildrid Yeo, Paul Gissen

Source: Molecular Genetics and Metabolism Reports, Vol 37, Iss , Pp 101020- (2023)

Subject Terms: Liver transplantation, Ornithine transcarbamylase deficiency, Metabolic correction, Neurological outcome, Growth, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2214426923000666; https://doaj.org/toc/2214-4269

Access URL: https://doaj.org/article/4b378179f00043a097ba2e977f075d5f

Transient elastography and von Willebrand factor as predictors of portal hypertension and decompensation in children

Authors: Akshat Goel, Robert Hegarty, Shweta Dixit, Bethany Tucker, Abdel Douiri, Eirini Kyrana, Vandana Jain, Anil Dhawan, Tassos Grammatikopoulos

Source: JHEP Reports, Vol 5, Iss 12, Pp 100935- (2023)

Subject Terms: Biomarkers, Clinically significant varices, Variceal Bleeding, Liver Stiffness, Spleen Stiffness, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923002665; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/5438b6b89dc84cf0b845f546a4966698

Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease

Authors: Gabriella Assante, Sriram Chandrasekaran, Stanley Ng, Aikaterini Tourna, Carolina H. Chung, Kowsar A. Isse, Jasmine L. Banks, Ugo Soffientini, Celine Filippi, Anil Dhawan, Mo Liu, Steven G. Rozen, Matthew Hoare, Peter Campbell, J. William O. Ballard, Nigel Turner, Margaret J. Morris, Shilpa Chokshi, Neil A. Youngson

Source: Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)

Subject Terms: Steatosis, Histone acetylation, Hepatocellular carcinoma, NAFLD, ARLD, Telomerase, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/4c59d9255acd4dbe97a0e6aee280b26c

Liver Disease and Risk of Hepatocellular Carcinoma in Children With Mutations in TALDO1

Authors: Tassos Grammatikopoulos, Nedim Hadzic, Pierre Foskett, Sandra Strautnieks, Marianne Samyn, Roshni Vara, Anil Dhawan, Jozef Hertecant, Fatma Al Jasmi, Obydur Rahman, University of Washington Center for Mendelian Genomics, Maesha Deheragoda, Laura N. Bull, Richard J Thompson

Source: Hepatology Communications, Vol 6, Iss 3, Pp 473-479 (2022)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/2471-254X

Access URL: https://doaj.org/article/940c477ffd0640db99f0a2ccb9b4a507

Impact of progressive familial intrahepatic cholestasis on caregivers: caregiver-reported outcomes from the multinational PICTURE study

Authors: Claudia Mighiu, Sonia O’Hara, Enrico Ferri Grazzi, Karen F. Murray, Jörn M. Schattenberg, Emily Ventura, Melanie Karakaidos, Alison Taylor, Harpreet Brrang, Anil Dhawan, Jose Willemse, Alan Finnegan

Source: Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-9 (2022)

Subject Terms: Progressive familial intrahepatic cholestasis, Caregiver burden, Work productivity, Employment, Patient-reported outcomes, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1750-1172

Access URL: https://doaj.org/article/e0b23825ac854b53acaf7e8711c99ff9

Fatty liver disease in children (MAFLD/PeFLD Type 2): unique classification considerations and challenges

Authors: Robert Hegarty, Eirini Kyrana, Emer Fitzpatrick, Anil Dhawan

Source: Therapeutic Advances in Endocrinology and Metabolism, Vol 14 (2023)

Subject Terms: Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://doaj.org/toc/2042-0196

Access URL: https://doaj.org/article/3c0120fedce04c3f8fde2e17a55be6d3

Correction: Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease

Authors: Gabriella Assante, Sriram Chandrasekaran, Stanley Ng, Aikaterini Tourna, Carolina H. Chung, Kowsar A. Isse, Jasmine L. Banks, Ugo Soffientini, Celine Filippi, Anil Dhawan, Mo Liu, Steven G. Rozen, Matthew Hoare, Peter Campbell, J. William O. Ballard, Nigel Turner, Margaret J. Morris, Shilpa Chokshi, Neil A. Youngson

Source: Genome Medicine, Vol 15, Iss 1, Pp 1-1 (2023)

Subject Terms: Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/eb93debd63754739be2c1d678c35747f

Epidemiology and Risk Factors for Viral Infections in Pediatric Liver Transplant Recipients and Impact on Outcome

Authors: Hala Abdullatif, Anil Dhawan, Anita Verma

Source: Viruses, Vol 15, Iss 5, p 1059 (2023)

Subject Terms: liver transplantation, CMV, EBV, non-EBV-CMV viral infections, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/15/5/1059; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/5b37dc7b1a3a437480006815ea13dd88

Outcomes of adults who received liver transplant as young children

Authors: Sunitha Vimalesvaran, Lara Neves Souza, Maesha Deheragoda, Marianne Samyn, Jemma Day, Anita Verma, Hector Vilca-Melendez, Mohamed Rela, Nigel Heaton, Anil Dhawan

Source: EClinicalMedicine, Vol 38, Iss , Pp 100987- (2021)

Subject Terms: pediatric, Liver transplantation, long-term, biopsychosocial, outcomes, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537021002674; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/746e99f3266743a29cb0887c013686a5

Cellular Therapies in Pediatric Liver Diseases

Authors: Sunitha Vimalesvaran, Jessica Nulty, Anil Dhawan

Source: Cells, Vol 11, Iss 16, p 2483 (2022)

Subject Terms: pediatric liver transplantation, hepatocyte transplantation, mesenchymal stromal cell, acute liver failure, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/16/2483; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/21bd436e770a4d9e9760153ed9637bc3

Biliary-Atresia-Associated Mannosidase-1-Alpha-2 Gene Regulates Biliary and Ciliary Morphogenesis and Laterality

Authors: Juhoon So, Mylarappa Ningappa, Joseph Glessner, Jun Min, Chethan Ashokkumar, Sarangarajan Ranganathan, Brandon W. Higgs, Dong Li, Qing Sun, Lori Schmitt, Amy C. Biery, Steven Dobrowolski, Christine Trautz, Leah Fuhrman, Molly Christine Schwartz, Nikolai Thomas Klena, Joseph Fusco, Krishna Prasadan, Morayooluwa Adenuga, Nada Mohamed, Qi Yan, Wei Chen, William Horne, Anil Dhawan, Khalid Sharif, Deirdre Kelly, Robert H Squires, George K. Gittes, Hakon Hakonarson, Victor Morell, Cecilia Lo, Shankar Subramaniam, Donghun Shin, Rakesh Sindhi

Source: Frontiers in Physiology, Vol 11 (2020)

Subject Terms: biliary atresia, liver transplantation, cilia, biliary morphogenesis, laterality, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2020.538701/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/e1c329030930403a8e3a5542aa7c32a8

Epidemiology, Risk Factors and Outcome Due to Multidrug Resistant Organisms in Paediatric Liver Transplant Patients in the Era of Antimicrobial Stewardship and Screening

Authors: Anita Verma, Sunitha Vimalesvaran, Anil Dhawan

Source: Antibiotics, Vol 11, Iss 3, p 387 (2022)

Subject Terms: liver transplantation, paediatric, multidrug resistant organisms, antimicrobial stewardship, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/11/3/387; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/59588440b2934c2a8ea852d92274b4f7

Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications

Authors: John Ong, Maria Paola Serra, Joe Segal, Ana-Maria Cujba, Soon Seng Ng, Richard Butler, Val Millar, Stephanie Hatch, Salman Zimri, Hiroyuki Koike, Karen Chan, Andrew Bonham, Michelle Walk, Ty Voss, Nigel Heaton, Ragai Mitry, Anil Dhawan, Daniel Ebner, Davide Danovi, Hiromitsu Nakauchi, S. Tamir Rashid

Source: Stem Cell Reports, Vol 10, Iss 3, Pp 693-702 (2018)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671118300511; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/7c1f980085ad4d33ad10a8f4d8dd7616

Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease

Authors: Christos Spanos, Elaina M. Maldonado, Ciarán P. Fisher, Petchpailin Leenutaphong, Ernesto Oviedo-Orta, David Windridge, Francisco J. Salguero, Alexandra Bermúdez-Fajardo, Mark E. Weeks, Caroline Evans, Bernard M. Corfe, Naila Rabbani, Paul J. Thornalley, Michael H. Miller, Huan Wang, John F. Dillon, Alberto Quaglia, Anil Dhawan, Emer Fitzpatrick, J. Bernadette Moore

Source: Proteome Science, Vol 16, Iss 1, Pp 1-16 (2018)

Subject Terms: Non-alcoholic fatty liver disease, Glyoxalase, Methylglyoxal, Proteomics, iTRAQ, Cytology, QH573-671

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12953-018-0131-y; https://doaj.org/toc/1477-5956

Access URL: https://doaj.org/article/f4d6753e39c246199b19b878476f18b9

A New High Throughput Screening Platform for Cell Encapsulation in Alginate Hydrogel Shows Improved Hepatocyte Functions by Mesenchymal Stromal Cells Co-encapsulation

Authors: Valeria Iansante, Anil Dhawan, Fatma Masmoudi, Charlotte A. Lee, Raquel Fernandez-Dacosta, Simon Walker, Emer Fitzpatrick, Ragai R. Mitry, Céline Filippi

Source: Frontiers in Medicine, Vol 5 (2018)

Subject Terms: hepatocytes, mesenchymal stromal cells, alginate, hydrogel, microbeads, high throughput screening, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmed.2018.00216/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/1365163c4e2a4251bfc546dbc9ea5dcd

Cryopreservation of Hepatocyte Microbeads for Clinical Transplantation

Authors: Suttiruk Jitraruch, Anil Dhawan, Robin D. Hughes, Celine Filippi, Sharon C. Lehec, Leanne Glover, Ragai R. Mitry

Source: Cell Transplantation, Vol 26 (2017)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/0963-6897; https://doaj.org/toc/1555-3892

Access URL: https://doaj.org/article/71d8bae42112478f8d0b39394ecc56d9

Instant Blood-Mediated Inflammatory Reaction in Hepatocyte Transplantation: Current Status and Future Perspectives

Authors: Charlotte A. Lee, Anil Dhawan, Richard A. Smith, Ragai R. Mitry, Emer Fitzpatrick

Source: Cell Transplantation, Vol 25 (2016)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/0963-6897; https://doaj.org/toc/1555-3892

Access URL: https://doaj.org/article/f54e8087701c4838b85b63997757604b

Use of indocyanine green for functional assessment of human hepatocytes for transplantation

Authors: Cheng-Maw Ho, Anil Dhawan, Robin D. Hughes, Sharon C. Lehec, Juliana Puppi, Christina Philippeos, Po-Huang Lee, Ragai R. Mitry

Source: Asian Journal of Surgery, Vol 35, Iss 1, Pp 9-15 (2012)

Subject Terms: cell transplantation, functional assessment, human hepatocyte transplantation, indocyanine green, taurine, Surgery, RD1-811

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1015958412000371; https://doaj.org/toc/1015-9584

Access URL: https://doaj.org/article/47acad8115ce4221af5ed96c6711aafc