A Neglected Gene: The Role of the ANG Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis.

Authors: Yu Zhang¹, Yanan Li¹, Shen Bin², Xi Cheng¹, Qi Niu¹ md_new@sina.com

Source: Aging & Disease. Jan2025, Vol. 16 Issue 1, p13-32. 20p.

Subject Terms: *ANGIOGENIN, *GENETICS of amyotrophic lateral sclerosis, *AMYOTROPHIC lateral sclerosis treatment

Association of plasma angiogenin with risk of major cardiovascular events in type 2 diabetes.

Authors: Gurung, Resham L.^1,2 (AUTHOR), Liu, Sylvia¹ (AUTHOR), Liu, Jian-Jun¹ (AUTHOR), M., Yiamunaa¹ (AUTHOR), Zheng, Huili¹ (AUTHOR), Chan, Clara¹ (AUTHOR), Ang, Keven¹ (AUTHOR), Subramaniam, Tavintharan³ (AUTHOR), Sum, Chee Fang³ (AUTHOR), Lim, Su Chi^1,3,4,5 (AUTHOR) lim.su.chi@ktph.com.sg

Source: Cardiovascular Diabetology. 2/15/2024, Vol. 23 Issue 1, p1-8. 8p.

Subject Terms: *ANGIOGENIN, *TYPE 2 diabetes, *MAJOR adverse cardiovascular events, *CARDIOVASCULAR diseases risk factors

Evaluation of the Effect of Recombinant Human Angiogenin on the Functional Properties of EA.Hy926 Endothelial Cells and Human Skin Fibroblasts In Vitro.

Authors: Lykov, A. P.¹ (AUTHOR) aplykov2@mail.ru, Goryachkin, A. M.² (AUTHOR), Surovtseva, M. A.¹ (AUTHOR), Drovosekov, M. N.² (AUTHOR), Poveshchenko, O. V.¹ (AUTHOR)

Source: Bulletin of Experimental Biology & Medicine. Jan2025, Vol. 178 Issue 3, p367-370. 4p.

Subject Terms: *SERUM-free culture media, *ANGIOGENIN, *ENDOTHELIAL cells, *FACTORS of production, *FIBROBLASTS

Vascular remodeling and TSLP/angiogenin overexpression in severe mixed asthma.

Authors: Bertolini, Francesca, Carriero, Vitina M.A., Arrigo, Elisa, Guida, Giuseppe, Levra, Stefano, Pizzimenti, Stefano, Profita, Mirella, Gnemmi, Isabella, Di Stefano, Antonino, Ricciardolo, Fabio L.M.

Source: Respiratory Research; 2/28/2025, Vol. 26 Issue 1, p1-14, 14p

Subject Terms: VASCULAR remodeling, THYMIC stromal lymphopoietin, EOSINOPHILS, ANGIOGENIN, NEUTROPHILS, ASTHMA, DISEASE exacerbation

Colorectal Cancer-Associated Myofibroblasts Exhibit Enhanced Angiogenin Expression and Signaling via the PLXNB2 Receptor.

Authors: Hu, Alexander¹ (AUTHOR), Nussbaum, Yulia I.^1,2 (AUTHOR), Mitchem, Jonathan^2,3 (AUTHOR), Yoo, James¹ (AUTHOR) jyoo@bwh.harvard.edu

Source: Journal of Surgical Research. Apr2024, Vol. 296, p273-280. 8p.

Subject Terms: *ANGIOGENIN, *GENE expression, *MYOFIBROBLASTS, *CELL receptors, *CELL communication, *GASTROINTESTINAL stromal tumors

Company/Entity: NATIONAL Center for Biotechnology Information (U.S.)

Role of circulating angiogenin levels in portal hypertension and TIPS.

Authors: Queck, Alexander¹ (AUTHOR), Uschner, Frank E.¹ (AUTHOR), Ferstl, Philip G.¹ (AUTHOR), Schulz, Martin¹ (AUTHOR), Brol, Maximilian J.¹ (AUTHOR), Praktiknjo, Michael² (AUTHOR), Schierwagen, Robert¹ (AUTHOR), Klein, Sabine¹ (AUTHOR), Strassburg, Christian P.² (AUTHOR), Meyer, Carsten³ (AUTHOR), Jansen, Christian² (AUTHOR), Berres, Marie-Luise⁴ (AUTHOR), Trebicka, Jonel^1,5 (AUTHOR) Jonel.Trebicka@kgu.de

Source: PLoS ONE. 8/25/2021, Vol. 16 Issue 8, p1-13. 13p.

Subject Terms: *PORTAL hypertension, *ANGIOGENIN, *VENOUS pressure, *HEPATIC portal system, *TREATMENT effectiveness, *PATHOGENESIS, *ANGIOGRAPHY, *PORTAL vein

Secretome from estrogen-responding human placenta-derived mesenchymal stem cells rescues ovarian function and circadian rhythm in mice with cyclophosphamide-induced primary ovarian insufficiency

Authors: Duy-Cuong Le, Mai-Huong T. Ngo, Yung-Che Kuo, Shu-Hwa Chen, Chung-Yen Lin, Thai-Yen Ling, Quoc Thao Trang Pham, Heng-Kien Au, Jihwan Myung, Yen-Hua Huang

Source: Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-29 (2024)

Subject Terms: Placenta mesenchymal stem cell, Estrogen receptor, Primary ovarian insufficiency, Ovarian circadian rhythm disorder, Angiogenin, Exosomal miRNA, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/0b97f6b1c17d4239a8ce8de9c3b219ea

Loss of angiogenin function is related to earlier ALS onset and a paradoxical increase in ALS duration.

Authors: Aluri, Krishna C.^1,2, Salisbury, Joseph P.^1,2, Prehn, Jochen H. M.³, Agar, Jeffrey N.^1,2,4 j.agar@northeastern.edu

Source: Scientific Reports. 2/28/2020, Vol. 10 Issue 1, p1-13. 13p.

Subject Terms: *ANGIOGENIN, *AMYOTROPHIC lateral sclerosis, *PARKINSON'S disease, *RIBONUCLEASES, *NEUROLOGISTS

The Impact of Thyroiditis on the Immune Profile in Young Patients with Uncomplicated Type 1 Diabetes.

Authors: Neubauer-Geryk, Jolanta, Myśliwiec, Małgorzata, Zorena, Katarzyna, Bieniaszewski, Leszek

Source: International Journal of Molecular Sciences; Sep2024, Vol. 25 Issue 17, p9721, 14p

Subject Terms: AUTOIMMUNE thyroiditis, TYPE 1 diabetes, VASCULAR endothelial growth factors, THYROID diseases, ANGIOGENIN

Novel biomarkers in the saliva of healthy young males and females in a randomized crossover study on sedentary time: An exploratory analysis.

Authors: Meens Miller, Emmeline, O'Rourke, Nicholas, Jeffrey, Michael, Green-Johnson, Julia, Dogra, Shilpa

Source: PLoS ONE; 8/20/2024, Vol. 19 Issue 8, p1-15, 15p

Subject Terms: EXERCISE therapy, GROWTH factors, HEART beat, ANGIOGENIN, BIOMARKERS

Effects of ALS-associated 5’tiRNAGly-GCC on the transcriptomic and proteomic profile of primary neurons in vitro

Authors: Jirström, Elisabeth ^{a, b}, Matveeva, Anna ^{a, b}, Baindoor, Sharada ^a, Donovan, Paul ^{a, b}, Ma, Qilian ^{a, b, c}, Morrissey, Elena Perez ^{a, b}, Arijs, Ingrid ^{d, e}, Boeckx, Bram ^{d, e}, Lambrechts, Diether ^{d, e}, Garcia-Munoz, Amaya ^f, Dillon, Eugène T. ^g, Wynne, Kieran ^f, Ying, Zheng ^c, Matallanas, David ^f, Hogg, Marion C. ^{a, b, 1}, Prehn, Jochen H.M. ^{a, b, ⁎}

Source: In Experimental Neurology March 2025 385

Non-enzymatic glycation of human angiogenin: Effects on enzymatic activity and binding to hRI and DNA.

Authors: Panda, Atashi¹ (AUTHOR), Sabnam, Kabira¹ (AUTHOR), De, Soumya² (AUTHOR), Dasgupta, Swagata¹ (AUTHOR) swagata@chem.iitkgp.ac.in

Source: Biochimie. May2023, Vol. 208, p151-159. 9p.

Subject Terms: *ANGIOGENIN, *DNA, *RECEPTOR for advanced glycation end products (RAGE), *PROTEIN-protein interactions, *RIBONUCLEASES, *RIBOSE

Copper(II) binding properties and anticancer activity of peptide fragments from a β-strand region of angiogenin protein

Authors: Magrì, Antonio ^a, Marrone, Alessandro ^b, Tolbatov, Iogann ^{c, ⁎}, Tabbì, Giovanni ^a, Chiaverini, Lorenzo ^d, Attanasio, Francesco ^a, Marzo, Tiziano ^d, Naletova, Irina ^{a, ⁎}, La Mendola, Diego ^{d, ⁎}

Source: In Inorganica Chimica Acta 1 July 2025 582

The ANGPTL4-HIF-1α loop: a critical regulator of renal interstitial fibrosis

Authors: Yan Li, Shuang Chen, Qian Yang, Xiao Liu, Weiming Zhou, Ting Kang, Weihua Wu, Santao Ou

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)

Subject Terms: Chronic kidney disease, Renal interstitial fibrosis, Angiogenin-like 4, Hypoxia-inducible factor-1α, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/eb86df9f10d84aaf87d76242ca06ab22

New link between RNH1 and E2F1: regulates the development of lung adenocarcinoma

Authors: Wenyue Zhao, Yang Liu, Ying Yang, Liming Wang

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)

Subject Terms: Lung adenocarcinoma, Ribonuclease/angiogenin inhibitor 1 (RNH1), E2F transcription factor 1 (E2F1), Tumorigenesis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/b0f2a0d1c2824433ab1fea24999bebeb

Severity of hypoxic ischemic encephalopathy correlates with increased expression of angiogenin in neonates.

Authors: El Shimi, M. Sami¹, Abdou, R.M.¹ raniaabdou0811@yahoo.com, Fathey, M.², Mostafa, S.¹

Source: Journal of Neonatal - Perinatal Medicine. 2018, Vol. 11 Issue 2, p185-190. 6p. 3 Charts, 2 Graphs.

Subject Terms: *ANGIOGENIN, *CEREBRAL anoxia, *BRAIN damage, *NEWBORN infants' injuries, *BIRTH injuries, *THERAPEUTICS

Effects of Pathogenic Mutants of the Neuroprotective RNase 5-Angiogenin in Amyotrophic Lateral Sclerosis (ALS).

Authors: Gotte, Giovanni

Source: Genes; Jun2024, Vol. 15 Issue 6, p738, 22p

Subject Terms: AMYOTROPHIC lateral sclerosis, NEURODEGENERATION, MISSENSE mutation, NEUROPROTECTIVE agents, RIBONUCLEASES, ANGIOGENIN

Activation of angiogenin expression in macrophages by lipopolysaccharide via the TLR4/NF-κB pathway in colitis

Authors: Yao Zhengrong, Bai Rongpan, Liu Wei, Liu Yaxing, Zhou Wei, Xu Zhengping, Sheng Jinghao

Source: Acta Biochimica et Biophysica Sinica, Vol 56, Pp 857-865 (2024)

Subject Terms: angiogenin, macrophage, lipopolysaccharide, TLR4, NF-κB, Biochemistry, QD415-436, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1672-9145

Access URL: https://doaj.org/article/5dba5f93810d41f4bbe37ccd1e2f983f

Structure of angiogenin dimer bound to double‐stranded RNA.

Authors: Sievers, Katharina¹ (AUTHOR) katharina.sievers@uni-goettingen.de, Ficner, Ralf¹ (AUTHOR)

Source: Acta Crystallographica: Section F, Structural Biology Communications. Sep2022, Vol. 78 Issue 9, p330-337. 8p.

Subject Terms: *DOUBLE-stranded RNA, *ANGIOGENIN, *ENDONUCLEASES, *RIBONUCLEASE A, *RNA

Research progress on the structure, function, and use of angiogenin in malignant tumours

Authors: Mao, Mingwen ^{a, b}, Chen, Weina ^c, Ye, Dong ^{b, ⁎}

Source: In Heliyon 15 May 2024 10(9)