Decursinol angelate relieves inflammatory bowel disease by inhibiting the ROS/TXNIP/NLRP3 pathway and pyroptosis

Authors: Yudi Wang, Jiamin Wang, Yonghu Chen, Xuezheng Li, Zhe Jiang

Source: Frontiers in Pharmacology, Vol 15 (2025)

Subject Terms: angelica gigas nakai, NLRP3 inflammasome, IBD, pyroptosis, decursinol angelate, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1520040/full; https://doaj.org/toc/1663-9812

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Herbal extract (Cervus elaphus Linnaeus, Angelica gigas Nakai, and Astragalus membranaceus Bunge) ameliorates chronic fatigue: A randomized, placebo-controlled, double-blind trial

Authors: SoYoung Ahn, Parivash Jamrasi, Byunggul Lim, Ji-won Seo, Xinxing Li, Shu Jiang, Yunho Sung, Seo Hyun Ahn, Chaeyoung Shin, Dongjin Noh, Bora Jin, Seonjoo Lee, Ki Won Lee, Jin Soo Kim, Young Tae Koo, Wook Song

Source: Integrative Medicine Research, Vol 13, Iss 4, Pp 101085- (2024)

Subject Terms: Angelica gigas nakai, Anti-fatigue, Astragalus membranaceus bunge, Cervus elaphus Linnaeus, Exercise performance, Miscellaneous systems and treatments, RZ409.7-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213422024000659; https://doaj.org/toc/2213-4220

Access URL: https://doaj.org/article/719c017f43cb4f18924ca93f8e018b17

Anti-Oral Microbial Effect of Ethanol Extract of Angelica gigas Nakai

Authors: Soon-Jeong Jeong

Source: 치위생과학회지, Vol 24, Iss 1, Pp 54-61 (2024)

Subject Terms: aggregatibacter actinomycetemcomitans, angelica gigas nakai, anti-oral bacterial effect, cham-dang-gui, streptococcus mutans, Dentistry, RK1-715

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Relation: https://doaj.org/toc/2233-7679

Access URL: https://doaj.org/article/214c48faedb54bb6aa1aab4403dd4bb3

Effects of the Germinated Glycine max and Angelica gigas Nakai Mixture on Hepatic Lipid Metabolism and Bone Turnover Balance in Ovariectomized Rats

Authors: Sangmin Lee, Yunsang Cho, Jihye Choi, Hwal Choi, Tae Sung Jung, Jungkee Kwon

Source: Applied Sciences, Vol 13, Iss 8, p 5084 (2023)

Subject Terms: osteoporosis, Glycine max, Angelica gigas Nakai, bone turnover, osteoclastogenesis, lipid metabolism, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

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Relation: https://www.mdpi.com/2076-3417/13/8/5084; https://doaj.org/toc/2076-3417

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Hematopoietic Effects of Angelica gigas Nakai Extract on Cyclophosphamide-Induced Myelosuppression

Authors: Mincheol Kang, Seojin Park, Yuseong Chung, Je-Oh Lim, Jae Seon Kang, Jun Hong Park

Source: Plants, Vol 11, Iss 24, p 3476 (2022)

Subject Terms: Angelica gigas Nakai, myelosuppression, cyclophosphamide, hematopoiesis, Botany, QK1-989

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Relation: https://www.mdpi.com/2223-7747/11/24/3476; https://doaj.org/toc/2223-7747

Access URL: https://doaj.org/article/6fca9999e008405f8d83ad3e14c9a31e

Protective effects of a standardized extract (HemoHIM) using indomethacin- and ethanol/HCl-induced gastric mucosal injury models

Authors: Da-Ae Kwon, Yong Sang Kim, Sin Hwa Baek, Seul-Ki Kim, Hyun Kyu Kim, Sung-Kee Jo, Uhee Jung, Hae-Ran Park, Hak Sung Lee

Source: Pharmaceutical Biology, Vol 57, Iss 1, Pp 543-549 (2019)

Subject Terms: inflammation, gastritis, gastric ulcer, angelica gigas nakai, cnidium officinale makino, paeonia japonica miyabe, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1388-0209; https://doaj.org/toc/1744-5116

Access URL: https://doaj.org/article/a496a429b6754b1f9a7747d53c3b0742

Angelica gigas NAKAI and Its Active Compound, Decursin, Inhibit Cellular Injury as an Antioxidant by the Regulation of AMP-Activated Protein Kinase and YAP Signaling

Authors: Yu-Rim Song, Boyun Jang, Sung-Min Lee, Su-Jin Bae, Seon-Been Bak, Young-Woo Kim

Source: Molecules, Vol 27, Iss 6, p 1858 (2022)

Subject Terms: AMPK, YAP, Angelica gigas NAKAI, neuropsychiatry, mitochondria, dementia, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/6/1858; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/3edb7410b5a34a94806dc34f41c49ff9

Preventive effect of Angelica gigas Nakai extract oral administration on dry eye syndrome

Authors: Younje Lee, Kang Min Kim, Jae Seon Kang

Source: Asian Pacific Journal of Tropical Medicine, Vol 11, Iss 6, Pp 369-375 (2018)

Subject Terms: angelica gigas nakai, benzalkonium chloride, dry eye syndrome, Arctic medicine. Tropical medicine, RC955-962

File Description: electronic resource

Relation: http://www.apjtm.org/article.asp?issn=1995-7645;year=2018;volume=11;issue=6;spage=369;epage=375;aulast=Lee; https://doaj.org/toc/2352-4146

Access URL: https://doaj.org/article/6ff7c22fb2d147958e6a2d91a9343271

The topical application of low-temperature argon plasma enhances the anti-inflammatory effect of Jaun-ointment on DNCB-induced NC/Nga mice

Authors: Jeong-Hae Choi, Yeon-Suk Song, Hae-June Lee, Gyoo-Cheon Kim, Jin-Woo Hong

Source: BMC Complementary and Alternative Medicine, Vol 17, Iss 1, Pp 1-10 (2017)

Subject Terms: Low-temperature argon plasma, Transdermal drug delivery of herbal extracts, Jaun-ointment, Angelica gigas Nakai, Lithospermum erythrorhizon Siebold & Zucc, DNCB-induced cutaneous inflammation in NC/Nga, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12906-017-1850-9; https://doaj.org/toc/1472-6882

Access URL: https://doaj.org/article/cac8890b8eca40cda64de7bf91986e4f

Decursin and decursinol angelate-rich Angelica gigas Nakai extract suppresses de novo lipogenesis and alleviates nonalcoholic fatty liver disease and dyslipidemia in mice fed a high fat diet

Authors: Ui-Jin Bae, Mi-Ra Oh, Tae-Sung Jung, Soo-Wan Chae, Byung-Hyun Park

Source: Journal of Functional Foods, Vol 31, Iss , Pp 208-216 (2017)

Subject Terms: Angelica gigas Nakai, Decursin, Decursinol angelate, Lipogenesis, Sirt1, NAFLD, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464617300804; https://doaj.org/toc/1756-4646

Access URL: https://doaj.org/article/2ba06d2f125c42878caad7c5e9f01598

Antithrombotic Effect of the Ethanol Extract of Angelica gigas Nakai (AGE 232)

Authors: Pia Loreto Werlinger Bravo, Hui Jin, Hyunwoo Park, Min Sang Kim, Hirofumi Matsui, Hanki Lee, Joo-Won Suh

Source: Life, Vol 11, Iss 9, p 939 (2021)

Subject Terms: thrombus formation, acetylsalicylic acid, Angelica gigas Nakai, improvement of blood circulation, anti-platelet aggregation, bleeding in the gut, Science

File Description: electronic resource

Relation: https://www.mdpi.com/2075-1729/11/9/939; https://doaj.org/toc/2075-1729

Access URL: https://doaj.org/article/c3ac3003be3e47a4917dec690ac8d2cf

Therapeutic Effects of Decursin and Angelica gigas Nakai Root Extract in Gerbil Brain after Transient Ischemia via Protecting BBB Leakage and Astrocyte Endfeet Damage

Authors: Tae-Kyeong Lee, II-Jun Kang, Hyejin Sim, Jae-Chul Lee, Ji-Hyeon Ahn, Dae-Won Kim, Joon-Ha Park, Choong-Hyun Lee, Jong-Dai Kim, Moo-Ho Won, Soo-Young Choi

Source: Molecules, Vol 26, Iss 8, p 2161 (2021)

Subject Terms: Angelica gigas Nakai, astrocyte endfeet, blood–brain barrier, decursin, hippocampus, immunoglobulin G, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/8/2161; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/fa13274aa1a54475938f38e5efb8e934

Effects of Decursin and Angelica gigas Nakai Root Extract on Hair Growth in Mouse Dorsal Skin via Regulating Inflammatory Cytokines

Authors: Tae-Kyeong Lee, Bora Kim, Dae Won Kim, Ji Hyeon Ahn, Hyejin Sim, Jae-Chul Lee, Go Eun Yang, Young Her, Joon Ha Park, Hyun Sook Kim, Tae Heung Sim, Hyun Sam Lee, Moo-Ho Won

Source: Molecules, Vol 25, Iss 16, p 3697 (2020)

Subject Terms: Angelica gigas Nakai, decursin, hair growth facilitator, hair loss, inflammation, Organic chemistry, QD241-441

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Relation: https://www.mdpi.com/1420-3049/25/16/3697; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/21dcb220a28044798bf04f3a4d1dd97f

The Characteristics of the Growth and the Active Compounds of Angelica gigas Nakai in Cultivation Sites

Authors: Yunmi Park, Pil Sun Park, Dae Hui Jeong, Sujin Sim, Nahyun Kim, Hongwoo Park, Kwon Seok Jeon, Yurry Um, Mahn-Jo Kim

Source: Plants, Vol 9, Iss 7, p 823 (2020)

Subject Terms: Angelica gigas Nakai, active compounds, correlation analysis, growth, root, Botany, QK1-989

File Description: electronic resource

Relation: https://www.mdpi.com/2223-7747/9/7/823; https://doaj.org/toc/2223-7747

Access URL: https://doaj.org/article/c3adc941acd34d10bafd72c3cd9f0e24

Effect of Angelica gigas Nakai Ethanol Extract and Decursin on Human Pancreatic Cancer Cells

Authors: Bitna Kweon, Yo-Han Han, Ji-Ye Kee, Jeong-Geon Mun, Hee Dong Jeon, Dae Hwan Yoon, Byung-Min Choi, Seung-Heon Hong

Source: Molecules, Vol 25, Iss 9, p 2028 (2020)

Subject Terms: Angelica gigas Nakai, decursin, ultra-performance liquid chromatography, cell cycle arrest, apoptosis, matrix metalloproteinase, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/9/2028; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/203963ea8f7f41dab83be66384f33755

Layered Double Hydroxide Nanomaterials Encapsulating Angelica gigas Nakai Extract for Potential Anticancer Nanomedicine

Authors: Hyoung-Jun Kim, Gyeong Jin Lee, Ae-Jin Choi, Tae-Hyun Kim, Tae-il Kim, Jae-Min Oh

Source: Frontiers in Pharmacology, Vol 9 (2018)

Subject Terms: layered double hydroxide, Angelica gigas Nakai, anticancer activity, decursin species, nanobiohybrid, phytochemical, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2018.00723/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/cd7581e45e2a4b8cbf231cc7776de5db

Single-dose Intramuscular Injection Toxicology of Danggui Pharmacopuncture (DGP) in Sprague-Dawley Rats

Authors: SeungHo Sun, JongJin Jeong, Sunju Park, KwangHo Lee, JunSang Yu, HyungSik Seo, KiRok Kwon

Source: Journal of Pharmacopuncture, Vol 18, Iss 1, Pp 56-62 (2015)

Subject Terms: acupuncture, Angelica gigas nakai, Angelica gigantis radix, herbal medicine, pharmacopuncture, single-dose toxicity test, Medicine, Miscellaneous systems and treatments, RZ409.7-999, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2093-6966; https://doaj.org/toc/2234-6856

Access URL: https://doaj.org/article/e0604c71bccf4f3e82a62f81edb547bf

Bio- Fortification of Angelica gigas Nakai Nano-Powder Using Bio-Polymer by Hot Melt Extrusion to Enhance the Bioaccessibility and Functionality of Nutraceutical Compounds

Authors: Md Obyedul Kalam Azad, Wie Soo Kang, Jung Dae Lim, Cheol Ho Park

Source: Pharmaceuticals, Vol 13, Iss 1, p 3 (2019)

Subject Terms: angelica gigas nakai, biopolymer, hot melt extrusion, nanocomposite, phenolic compound, antioxidant capacity, solubility, bioaccessibility, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/13/1/3; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/c17ac79903ed4eccb84ebe47766b0f8b

Rapid and Efficient Separation of Decursin and Decursinol Angelate from Angelica gigas Nakai using Ionic Liquid, (BMIm)BF4, Combined with Crystallization

Authors: Alice Nguvoko Kiyonga, Ji-Hun An, Ki Yong Lee, Changjin Lim, Young-Ger Suh, Young-Won Chin, Kiwon Jung

Source: Molecules, Vol 24, Iss 13, p 2390 (2019)

Subject Terms: ionic liquids, decursin, decursinol angelate, Angelica gigas Nakai, crystallization, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/24/13/2390; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/07aa9d1ff6884c8a9998bced82ca4ad9

The Effect of Intravenous Injection of the Water Extract of Angelica gigas Nakai on Gliosis in the Middle Cerebral Artery Occlusion Rats

Authors: Bong-Keun Song, Yong-Cheol Jeon, Sun-Ae Kim, An-Na Shim, Keemoon Seong, Eon-Jeon Lee

Source: Journal of Pharmacopuncture, Vol 14, Iss 3, Pp 5-17 (2011)

Subject Terms: Angelica gigas Nakai, gliosis, CD81, GFAP, MCAO, Astrocyte, c-Fos, ERK, Medicine, Miscellaneous systems and treatments, RZ409.7-999, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2093-6966; https://doaj.org/toc/2234-6856

Access URL: https://doaj.org/article/b968ef9909ca46f5a69886dcce6f425f