Transcription Factor GATA4 Regulates Cell Type–Specific Splicing Through Direct Interaction With RNA in Human Induced Pluripotent Stem Cell–Derived Cardiac Progenitors

Authors: Zhu, Lili, Choudhary, Krishna, Gonzalez-Teran, Barbara, Ang, Yen-Sin, Thomas, Reuben, Stone, Nicole R., Liu, Lei, Zhou, Ping, Zhu, Chenchen, Ruan, Hongmei, Huang, Yu, Jin, Shibo, Pelonero, Angelo, Koback, Frances, Padmanabhan, Arun, Sadagopan, Nandhini, Hsu, Austin, Costa, Mauro W., Gifford, Casey A., van Bemmel, Joke G., Hüttenhain, Ruth, Vedantham, Vasanth, Conklin, Bruce R., Black, Brian L., Bruneau, Benoit G., Steinmetz, Lars, Krogan, Nevan J., Pollard, Katherine S., Srivastava, Deepak

Source: Circulation. 146(10):770-787

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100170822145.0x000001&indx=1&recIds=ETOCvdc_100170822145.0x000001

A New Therapeutic Framework for Atrial Fibrillation Drug Development

Authors: Ang, Yen-Sin, Rajamani, Sridharan, Haldar, Saptarsi M., Hüser, Jörg

Source: Circulation research. 127(1):184-201

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190132841.0x000001&indx=1&recIds=ETOCvdc_100190132841.0x000001

Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration

Authors: Mohamed, Tamer M.A., Ang, Yen-Sin, Radzinsky, Ethan, Zhou, Ping, Huang, Yu, Elfenbein, Arye, Foley, Amy, Magnitsky, Sergey, Srivastava, Deepak

Source: In Cell 22 March 2018 173(1):104-116

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis

Authors: Ang, Yen-Sin, Rivas, Renee N., Ribeiro, Alexandre J.S., Srivas, Rohith, Rivera, Janell, Stone, Nicole R., Pratt, Karishma, Mohamed, Tamer M.A., Fu, Ji-Dong, Spencer, C. Ian, Tippens, Nathaniel D., Li, Molong, Narasimha, Anil, Radzinsky, Ethan, Moon-Grady, Anita J., Yu, Haiyuan, Pruitt, Beth L., Snyder, Michael P., Srivastava, Deepak

Source: In Cell 15 December 2016 167(7):1734-1749

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness

Authors: Ribeiro, Alexandre J. S., Ang, Yen-Sin, Fu, Ji-Dong, Rivas, Renee N., Mohamed, Tamer M. A., Higgs, Gadryn C., Srivastava, Deepak, Pruitt, Beth L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Oct . 112(41), 12705-12710.

Access URL: https://www.jstor.org/stable/26465484

Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes

Authors: Ribeiro, Alexandre J.S., Schwab, Olivier, Mandegar, Mohammad A., Ang, Yen-Sin, Conklin, Bruce R., Srivastava, Deepak, Pruitt, Beth L.

Source: Circulation research. 120(10):1572-1583

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100044207605.0x000001&indx=1&recIds=ETOCvdc_100044207605.0x000001

Regulation of Embryonic and Induced Pluripotency by Aurora Kinase-p53 Signaling

Authors: Lee, Dung-Fang, Su, Jie, Ang, Yen-Sin, Carvajal-Vergara, Xonia, Mulero-Navarro, Sonia, Pereira, Carlos F., Gingold, Julian, Wang, Hung-Liang, Zhao, Ruiying, Sevilla, Ana, Darr, Henia, Williamson, Andrew J.K., Chang, Betty, Niu, Xiaohong, Aguilo, Francesca, Flores, Elsa R., Sher, Yuh-Pyng, Hung, Mien-Chie, Whetton, Anthony D., Gelb, Bruce D., Moore, Kateri A., Snoeck, Hans-Willem, Ma’ayan, Avi, Schaniel, Christoph, Lemischka, Ihor R.

Source: In Cell Stem Cell 3 August 2012 11(2):179-194

Stem cells and reprogramming: breaking the epigenetic barrier?

Authors: Ang, Yen-Sin, Gaspar-Maia, Alexandre, Lemischka, Ihor R., Bernstein, Emily

Source: In Trends in Pharmacological Sciences 2011 32(7):394-401

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

Authors: Ang, Yen-Sin, Tsai, Su-Yi, Lee, Dung-Fang, Monk, Jonathan, Su, Jie, Ratnakumar, Kajan, Ding, Junjun, Ge, Yongchao, Darr, Henia, Chang, Betty, Wang, Jianlong, Rendl, Michael, Bernstein, Emily, Schaniel, Christoph, Lemischka, Ihor R.

Source: In Cell 2011 145(2):183-197

Genomic Integrity Safeguards Self-Renewal in Embryonic Stem Cells

Authors: Su, Jie, Zhu, Dandan, Huo, Zijun, Gingold, Julian A., Ang, Yen-Sin, Tu, Jian, Zhou, Ruoji, Lin, Yu, Luo, Haidan, Yang, Huiling, Zhao, Ruiying, Schaniel, Christoph, Moore, Kateri A., Lemischka, Ihor R., Lee, Dung-Fang

Source: Cell reports. 28(6):1400-1409.e4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114474839.0x000001&indx=1&recIds=ETOCvdc_100114474839.0x000001

The molecular basis of ageing in stem cells

Authors: Tam, Wai-Leong, Ang, Yen-Sin, Lim, Bing

Source: In Mechanisms of Ageing and Development 2007 128(1):137-148

Construction and Validation of a Regulatory Network for Pluripotency and Self-Renewal of Mouse Embryonic Stem Cells.

Authors: Xu, Huilei^1,2,3, Ang, Yen-Sin^2,3, Sevilla, Ana^2,3, Lemischka, Ihor R.^1,2,3 ihor.lemischka@mssm.edu, Ma'ayan, Avi^1,3 avi.maayan@mssm.edu

Source: PLoS Computational Biology. Aug2014, Vol. 10 Issue 8, p1-14. 14p. 6 Diagrams.

Subject Terms: *EMBRYONIC stem cells, *LABORATORY mice, *PLURIPOTENT stem cells, *GENE expression, *BOOLEAN functions, *COMPUTATIONAL biology

Oxygen

Authors: Ang, Yen-Sin, Srivastava, Deepak

Source: Circulation research. 115(10):824-825

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCETOCvdc_100030307533.0x000001&indx=1&recIds=ETOCETOCvdc_100030307533.0x000001

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Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome.

Authors: Carvajal-Vergara, Xonia, Sevilla, Ana, D'Souza, Sunita L., Ang, Yen-Sin, Schaniel, Christoph, Lee, Dung-Fang, Lei Yang, Kaplan, Aaron D., Adler, Eric D., Rozov, Roye, YongChao Ge, Cohen, Ninette, Edelmann, Lisa J., Chang, Betty, Waghray, Avinash, Jie Su, Pardo, Sherly, Lichtenbelt, Klaske D., Tartaglia, Marco, Gelb, Bruce D.

Source: Nature. 6/10/2010, Vol. 465 Issue 7299, p808-812. 5p. 1 Diagram, 3 Graphs.

Subjects: STEM cell research, GENETIC disorders, PULMONARY stenosis, GENITAL diseases, DEAFNESS, PROTEIN kinases, PHOSPHATASES, CARDIOMYOPATHIES, HEART cells, PATIENTS

A Tuned Tension Regulates the Contractility of Cardiomyocytes Differentiated from Induced Pluripotent Stem Cells

Authors: Ribeiro, Alexandre J., Ang, Yen-Sin, Wilson, Robin E., Rivas, Renee N., Srivastava, Deepak, Pruitt, Beth L.

Source: In Biophysical Journal 16 February 2016 110(3) Supplement 1:294a-294a

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