Growth hormone releasing hormone signaling promotes Th17 cell differentiation and autoimmune inflammation

Authors: Lin Du, Bo Man Ho, Linbin Zhou, Yolanda Wong Ying Yip, Jing Na He, Yingying Wei, Clement C. Tham, Sun On Chan, Andrew V. Schally, Chi Pui Pang, Jian Li, Wai Kit Chu

Source: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f7cc99fe1f034fbb80b08ea07f7caf94

Growth hormone-releasing hormone antagonist MIA-602 inhibits inflammation induced by SARS-CoV-2 spike protein and bacterial lipopolysaccharide synergism in macrophages and human peripheral blood mononuclear cells

Authors: Giuseppina Granato, Iacopo Gesmundo, Francesca Pedrolli, Ramesh Kasarla, Laura Begani, Dana Banfi, Stefania Bruno, Tatiana Lopatina, Maria Felice Brizzi, Renzhi Cai, Wei Sha, Ezio Ghigo, Andrew V. Schally, Riccarda Granata

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: GHRH, GHRH antagonist, SARS-CoV-2 spike protein, macrophages, peripheral blood mononuclear cells (PBMC), inflammation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1231363/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/b14e8e79b3464a86bf94ec27c014b375

Age and Sex in the Development of Hepatic Encephalopathy: Role of Alcohol

Authors: Xiao Y. Tong, Hussain Hussain, Nagarajarao Shamaladevi, Michael D. Norenberg, Aya Fadel, Omar El Hiba, El got Abdeljalil, Bilal El-Mansoury, Deepak Kempuraj, Sampath Natarajan, Andrew V. Schally, Miklos Jaszberenyi, Luis Salgueiro, Michael J. Paidas, Arumugam R. Jayakumar

Source: Biology, Vol 13, Iss 4, p 228 (2024)

Subject Terms: alcohol, azoxymethane, brain edema, hepatic encephalopathy, thioacetamide, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2079-7737/13/4/228; https://doaj.org/toc/2079-7737

Access URL: https://doaj.org/article/be32dcb9f85c4c088e94bb026dcebcd2

Growth hormone-releasing hormone agonist attenuates vascular calcification in diabetic db/db mice

Authors: Hao-Lin Ren, Ruiping Cai, Ruize Xue, Yaoxia Zhang, Qian Xu, Xianyang Zhang, RenZhi Cai, Wei Sha, Andrew V. Schally, Ming-Sheng Zhou

Source: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

Subject Terms: vascular calcification, growth hormone-releasing hormone, diabetes, oxidative stress, vascular injury, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2023.1102525/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/a91dd026d7e041a0bf4e1cc7816a1aaa

Effects of GHRH Deficiency and GHRH Antagonism on Emotional Disorders in Mice

Authors: Lucia Recinella, Maria Loreta Libero, Serena Veschi, Anna Piro, Guya Diletta Marconi, Francesca Diomede, Annalisa Chiavaroli, Giustino Orlando, Claudio Ferrante, Rosalba Florio, Alessia Lamolinara, Renzhi Cai, Wei Sha, Andrew V. Schally, Roberto Salvatori, Luigi Brunetti, Sheila Leone

Source: Cells, Vol 12, Iss 22, p 2615 (2023)

Subject Terms: GHRH deficiency, GHRH antagonism, anxiety, depression, mood disorders, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/22/2615; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/176ee016bc7046c0a7ac5ff9c9711ebd

Estetrol Cotreatment of Androgen Deprivation Therapy in Infiltrating or Metastatic, Castration-sensitive Prostate Cancer: A Randomized, Double-blind, Phase II Trial (PCombi)

Authors: Herjan J.T. Coelingh Bennink, Jeroen A. van Moorselaar, E. David Crawford, Erik P.M. Roos, Diederik M. Somford, Ton A. Roeleveld, Tjard D. de Haan, Harm H.E. van Melick, Yacov Reisman, Yvette Zimmerman, Gonnie van Osta, Jan Krijgh, Neal D. Shore, Fred Saad, Andrew V. Schally, Frans M.J. Debruyne

Source: European Urology Open Science, Vol 28, Iss , Pp 52-61 (2021)

Subject Terms: Androgen deprivation therapy, Bone, Cardiovascular safety, Antitumor efficacy, Estetrol, Hot flushes, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666168321000793; https://doaj.org/toc/2666-1683

Access URL: https://doaj.org/article/dc4f5a0c31044f3baa728ff536e9797f

Protective effects of growth hormone-releasing hormone analogs in DSS-induced colitis in mice

Authors: Lucia Recinella, Annalisa Chiavaroli, Valentina Di Valerio, Serena Veschi, Giustino Orlando, Claudio Ferrante, Iacopo Gesmundo, Riccarda Granata, Renzhi Cai, Wei Sha, Andrew V. Schally, Rossano Lattanzio, Luigi Brunetti, Sheila Leone

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/182f84ae73e34728bf37d0224ab8d8f7

Expression Levels of GHRH-Receptor, pAkt and Hsp90 Predict 10-Year Overall Survival in Patients with Locally Advanced Rectal Cancer

Authors: Dávid Fodor, Éva Pozsgai, Andrew V. Schally, Zoltán László, Éva Gömöri, Éva Szabó, László Rumi, Dorottya Lőcsei, Árpád Boronkai, Szabolcs Bellyei

Source: Biomedicines, Vol 11, Iss 3, p 719 (2023)

Subject Terms: neoadjuvant radiochemotherapy, rectal cancer, Hsp90, GHRH-R, predictive markers, overall survival, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/11/3/719; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/8759efa106814de79e1b04c3600f0cd0

Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variants in Primary Human Endometrial Carcinomas: Novel Therapeutic Approaches

Authors: Zsuzsanna Szabo, Eva Juhasz, Andrew V. Schally, Balazs Dezso, Sandor Huga, Zoltan Hernadi, Gabor Halmos, Csongor Kiss

Source: Molecules, Vol 27, Iss 9, p 2671 (2022)

Subject Terms: GHRH, receptors for GHRH, splice variants, human endometrial carcinoma, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/9/2671; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/b83aea609b2f489987562eb70cebb2ba

P53, GHRH, inflammation and cancer

Authors: Nektarios Barabutis, Andrew V. Schally, Agnieszka Siejka

Source: EBioMedicine, Vol 37, Iss , Pp 557-562 (2018)

Subject Terms: Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396418304523; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/ae2bed4f5e234690b14b9ef7f1df02a5

Structural Motif Descriptors as a Way To Elucidate the Agonistic or Antagonistic Activity of Growth Hormone–Releasing Hormone Peptide Analogues

Authors: Kevin Jeanne Dit Fouque, Luis M. Salgueiro, Renzhi Cai, Wei Sha, Andrew V. Schally, Francisco Fernandez-Lima

Source: ACS Omega, Vol 3, Iss 7, Pp 7432-7440 (2018)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/a4c8cbde96cc467591f06a8e83ca2d81

Expression of Luteinizing Hormone-Releasing Hormone (LHRH) and Type-I LHRH Receptor in Transitional Cell Carcinoma Type of Human Bladder Cancer

Authors: Zsuzsanna Szabó, Balázs Dezső, Klára Fodor, Krisztián Szegedi, Tibor Flaskó, Erzsébet Szabó, Gábor Oláh, Éva Sipos, Nikoletta Dobos, János Gardi, Andrew V. Schally, Gábor Halmos

Source: Molecules, Vol 26, Iss 5, p 1253 (2021)

Subject Terms: LHRH receptor, targeted therapy, bladder cancer, radioligand binding assay, immunohistochemistry, Western Blot, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/5/1253; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/f04a73b9071f40f2b7c6e2ae5b74033e

Expression of Somatostatin Receptor Subtypes (SSTR-1–SSTR-5) in Pediatric Hematological and Oncological Disorders

Authors: Kristof Harda, Zsuzsanna Szabo, Eva Juhasz, Balazs Dezso, Csongor Kiss, Andrew V. Schally, Gabor Halmos

Source: Molecules, Vol 25, Iss 23, p 5775 (2020)

Subject Terms: hematological-oncological disorders in children, somatostatin receptors, somatostatin analogs, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/23/5775; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/d9282d16ef09477193a896583ee5045f

Correlation between the Expression of Angiogenic Factors and Stem Cell Markers in Human Uveal Melanoma

Authors: Klára Fodor, Éva Sipos, Nikoletta Dobos, János Nagy, Zita Steiber, Gábor Méhes, Kata Dull, Lóránt Székvölgyi, Andrew V. Schally, Gábor Halmos

Source: Life, Vol 10, Iss 12, p 310 (2020)

Subject Terms: uveal melanoma, cancer stem cell, angiogenesis, FZD6, VEGFA, Science

File Description: electronic resource

Relation: https://www.mdpi.com/2075-1729/10/12/310; https://doaj.org/toc/2075-1729

Access URL: https://doaj.org/article/2939d7e3c4f34e609d189b90f3ac5756

Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease

Authors: Chongxu Zhang, Tengjiao Cui, Renzhi Cai, Medhi Wangpaichitr, Mehdi Mirsaeidi, Andrew V. Schally, Robert M. Jackson

Source: Cells, Vol 9, Iss 10, p 2331 (2020)

Subject Terms: idiopathic pulmonary fibrosis, growth hormone-releasing hormone, antagonists, bleomycin, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/10/2331; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/f68cd9c9a77243458748497e722c0500

The effects of a growth hormone-releasing hormone antagonist and a gastrin-releasing peptide antagonist on intimal hyperplasia of the carotid artery after balloon injury in a diabetic rat model☆

Authors: John C. Moscona, Matthew N. Peters, Andrew V. Schally, Sudesh Srivastav, Patrice Delafontaine, Anand Irimpen

Source: Artery Research, Vol 19 (2017)

Subject Terms: Neointimal hyperplasia, Growth hormone-releasing hormone antagonist, Gastrin-releasing peptide antagonist, Arterial restenosis, Diabetes mellitus, Specialties of internal medicine, RC581-951, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.atlantis-press.com/article/125924982/view; https://doaj.org/toc/1876-4401

Access URL: https://doaj.org/article/f1db94ed0ec144cdb68ad211436aa838

Mini-Review: Novel Therapeutic Strategies to Blunt Actions of Pneumolysin in the Lungs

Authors: Martin Leustik, Maritza Romero, Helena Pillich, Norman L. Block, Ferenc G. Rick, Jonathan Lawson, Alexander Verin, Aluya Oseghale, Umapathy Siddaramappa, Boris Gorshkov, Evgeny Zemskov, Supriya Sridhar, Istvan Czikora, Rudolf Lucas, Andrew V. Schally, Trinad Chakraborty

Source: Toxins, Vol 5, Iss 7, Pp 1244-1260 (2013)

Subject Terms: pneumolysin, permeability edema, TNF, Growth Hormone-Releasing Hormone, Medicine

File Description: electronic resource

Relation: http://www.mdpi.com/2072-6651/5/7/1244; https://doaj.org/toc/2072-6651

Access URL: https://doaj.org/article/f087281299e04b3983ec7d671837bb53

Somatostatin Receptors as Molecular Targets in Human Uveal Melanoma

Authors: Kristof Harda, Zsuzsanna Szabo, Erzsebet Szabo, Gabor Olah, Klara Fodor, Csaba Szasz, Gabor Mehes, Andrew V. Schally, Gabor Halmos

Source: Molecules, Vol 23, Iss 7, p 1535 (2018)

Subject Terms: human uveal melanoma, somatostatin receptors, molecular targets SSTR-1-5, cancer therapy, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/23/7/1535; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/e6fe89552388451195697b29533676cb

Antagonists of Growth Hormone-Releasing Hormone Inhibit the Growth of U-87MG Human Glioblastoma in Nude Mice

Authors: Hippokratis Kiaris, Andrew V. Schally, Jozsef L. Varga

Source: Neoplasia: An International Journal for Oncology Research, Vol 2, Iss 3, Pp 242-250 (2000)

Subject Terms: cancer therapy, IGF, IGF receptor, brain tumors, GH-RH, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558600800330; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/b31d6d3841b94023b2a4a94b27b9f2c8

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