Identification of functionally connected multi-omic biomarkers for Alzheimer's disease using modularity-constrained Lasso.

Authors: Linhui Xie, Pradeep Varathan, Kwangsik Nho, Andrew J Saykin, Paul Salama, Jingwen Yan

Source: PLoS ONE, Vol 15, Iss 6, p e0234748 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b0de73e770324f4a88e0310765730c6f

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease.

Authors: Seonjoo Lee, Molly E Zimmerman, Atul Narkhede, Sara E Nasrabady, Giuseppe Tosto, Irene B Meier, Tammie L S Benzinger, Daniel S Marcus, Anne M Fagan, Nick C Fox, Nigel J Cairns, David M Holtzman, Virginia Buckles, Bernardino Ghetti, Eric McDade, Ralph N Martins, Andrew J Saykin, Colin L Masters, John M Ringman, Stefan Fӧrster, Peter R Schofield, Reisa A Sperling, Keith A Johnson, Jasmeer P Chhatwal, Stephen Salloway, Stephen Correia, Clifford R Jack, Michael Weiner, Randall J Bateman, John C Morris, Richard Mayeux, Adam M Brickman, Dominantly Inherited Alzheimer Network

Source: PLoS ONE, Vol 13, Iss 5, p e0195838 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5942789?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ed7c9a6ecadf43f2bcdf1faf91145ddd

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study.

Authors: Vijay R Varma, Anup M Oommen, Sudhir Varma, Ramon Casanova, Yang An, Ryan M Andrews, Richard O'Brien, Olga Pletnikova, Juan C Troncoso, Jon Toledo, Rebecca Baillie, Matthias Arnold, Gabi Kastenmueller, Kwangsik Nho, P Murali Doraiswamy, Andrew J Saykin, Rima Kaddurah-Daouk, Cristina Legido-Quigley, Madhav Thambisetty

Source: PLoS Medicine, Vol 15, Iss 1, p e1002482 (2018)

Subject Terms: Medicine

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5784884?pdf=render; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/22f7f44d5e424f9fae92e9cc4533ed09

Mapping longitudinal scientific progress, collaboration and impact of the Alzheimer's disease neuroimaging initiative.

Authors: Xiaohui Yao, Jingwen Yan, Michael Ginda, Katy Börner, Andrew J Saykin, Li Shen, Alzheimer’s Disease Neuroimaging Initiative

Source: PLoS ONE, Vol 12, Iss 11, p e0186095 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5667864?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1ad54934c26d4787b82480ef74a83e7a

Increased Brain Connectivity In Early Postmenopausal Women with Subjective Cognitive Impairment

Authors: Jennifer N Vega, Lilia Zurkovsky, Kimberly Albert, Alyssa Melo, Brian D Boyd, Julie Dumas, Neil Woodward, Brenna C McDonald, Andrew J Saykin, Joon Hyuk Park, Magdalena Naylor, Paul A Newhouse

Source: Frontiers in Neuroscience, Vol 10 (2016)

Subject Terms: Estrogens, functional connectivity, Resting-state fMRI, postmenopausal women, Subjective Cognitive Complaints, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00433/full; https://doaj.org/toc/1662-453X

Access URL: https://doaj.org/article/0a291cb5cd814c14b832ee8e34bf41b6

Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group.

Authors: Yi Su, Tyler M Blazey, Christopher J Owen, Jon J Christensen, Karl Friedrichsen, Nelly Joseph-Mathurin, Qing Wang, Russ C Hornbeck, Beau M Ances, Abraham Z Snyder, Lisa A Cash, Robert A Koeppe, William E Klunk, Douglas Galasko, Adam M Brickman, Eric McDade, John M Ringman, Paul M Thompson, Andrew J Saykin, Bernardino Ghetti, Reisa A Sperling, Keith A Johnson, Stephen P Salloway, Peter R Schofield, Colin L Masters, Victor L Villemagne, Nick C Fox, Stefan Förster, Kewei Chen, Eric M Reiman, Chengjie Xiong, Daniel S Marcus, Michael W Weiner, John C Morris, Randall J Bateman, Tammie L S Benzinger, Dominantly Inherited Alzheimer Network

Source: PLoS ONE, Vol 11, Iss 9, p e0163669 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5029931?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/34776afea7e04c56aaf53449f4d482fc

Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group.

Authors: Yi Su, Tyler M Blazey, Christopher J Owen, Jon J Christensen, Karl Friedrichsen, Nelly Joseph-Mathurin, Qing Wang, Russ C Hornbeck, Beau M Ances, Abraham Z Snyder, Lisa A Cash, Robert A Koeppe, William E Klunk, Douglas Galasko, Adam M Brickman, Eric McDade, John M Ringman, Paul M Thompson, Andrew J Saykin, Bernardino Ghetti, Reisa A Sperling, Keith A Johnson, Stephen P Salloway, Peter R Schofield, Colin L Masters, Victor L Villemagne, Nick C Fox, Stefan Förster, Kewei Chen, Eric M Reiman, Chengjie Xiong, Daniel S Marcus, Michael W Weiner, John C Morris, Randall J Bateman, Tammie L S Benzinger, Dominantly Inherited Alzheimer Network

Source: PLoS ONE, Vol 11, Iss 3, p e0152082 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3c1e448b15fa468cb6de83c58a76a317

Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer’s disease continuum

Authors: Junhao Wen, Zhijian Yang, Ilya M. Nasrallah, Yuhan Cui, Guray Erus, Dhivya Srinivasan, Ahmed Abdulkadir, Elizabeth Mamourian, Gyujoon Hwang, Ashish Singh, Mark Bergman, Jingxuan Bao, Erdem Varol, Zhen Zhou, Aleix Boquet-Pujadas, Jiong Chen, Arthur W. Toga, Andrew J. Saykin, Timothy J. Hohman, Paul M. Thompson, Sylvia Villeneuve, Randy Gollub, Aristeidis Sotiras, Katharina Wittfeld, Hans J. Grabe, Duygu Tosun, Murat Bilgel, Yang An, Daniel S. Marcus, Pamela LaMontagne, Tammie L. Benzinger, Susan R. Heckbert, Thomas R. Austin, Lenore J. Launer, Mark Espeland, Colin L. Masters, Paul Maruff, Jurgen Fripp, Sterling C. Johnson, John C. Morris, Marilyn S. Albert, R. Nick Bryan, Susan M. Resnick, Luigi Ferrucci, Yong Fan, Mohamad Habes, David Wolk, Li Shen, Haochang Shou, Christos Davatzikos

Source: Translational Psychiatry, Vol 14, Iss 1, Pp 1-14 (2024)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2158-3188

Access URL: https://doaj.org/article/56d631e8319148739bce0f8e8b35d005

miR‐133b as a potential regulator of a synaptic NPTX2 protein in Alzheimer's disease

Authors: Sang‐Won Han, Young Ho Park, Paula J Bice, David A. Bennett, SangYun Kim, Andrew J. Saykin, Kwangsik Nho

Source: Annals of Clinical and Translational Neurology, Vol 11, Iss 10, Pp 2799-2804 (2024)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2328-9503

Access URL: https://doaj.org/article/0de7246f31f447c58a400279cbcd01b2

Coupled pulsatile vascular and paravascular fluid dynamics in the human brain

Authors: Adam M. Wright, Yu-Chien Wu, Ho-Ching Yang, Shannon L. Risacher, Andrew J. Saykin, Yunjie Tong, Qiuting Wen

Source: Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-12 (2024)

Subject Terms: Neurofluids, Non-invasive imaging, Cerebrospinal fluid flow, Dynamic diffusion-weighted imaging (dynDWI), Functional MRI (fMRI), Paravascular CSF (pCSF), Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2045-8118

Access URL: https://doaj.org/article/dd6915e075624a428a6dd64f508b45b2

CYP1B1-RMDN2 Alzheimer’s disease endophenotype locus identified for cerebral tau PET

Authors: Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Thea Rosewood, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul Aisen, Reisa Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Svaldi, Clifford R. Jack, William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth Mormino, Rachel F. Buckley, Keith Johnson, Hyun-Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin-Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Department of Defense Alzheimer’s Disease Neuroimaging Initiative (DoD-ADNI), the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN), the Australian Imaging, Biomarker & Lifestyle Study (AIBL), Andrew J. Saykin

Source: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/534dba93d5bf4620975ce9a0f564baf7

Hippocampal Transcriptome-Guided Genetic Analysis of Correlated Episodic Memory Phenotypes in Alzheimer's Disease

Authors: Jingwen eYan, Sungeun eKim, Kwangsik eNho, Rui eChen, Shannon L. Risacher, Jason H Moore, Andrew J Saykin, Li eShen

Source: Frontiers in Genetics, Vol 6 (2015)

Subject Terms: Hippocampus, Alzheimer’s disease, episodic memory, Genetic associate study, correlated phenotypes, Genetics, QH426-470

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00117/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/6ddc8f85bdb54c43a2831d39b87271cd

Association of cancer history with Alzheimer’s disease onset and structural brain changes

Authors: Kelly Nicole Holohan Nudelman, Shannon L. Risacher, John D. West, Brenna C. McDonald, Sujuan eGao, Andrew J Saykin

Source: Frontiers in Physiology, Vol 5 (2014)

Subject Terms: Genetics, Cancer, MRI, Alzheimer’s disease, APOE, ADNI, Physiology, QP1-981

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00423/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/571d28923b244f9880030e0120fd0950

Black Americans' perceptions of Alzheimer's disease, a healthy brain, and strategies for brain health promotion

Authors: Johanne Eliacin, Angelina Polsinelli, Kenzie A. Cameron, Andrew J. Saykin, Sophia Wang

Source: PEC Innovation, Vol 4, Iss , Pp 100282- (2024)

Subject Terms: Black Americans, Alzheimer's disease, Perceptions and knowledge of AD disparities, Healthy brain, Mixed-methods, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S277262822400030X; https://doaj.org/toc/2772-6282

Access URL: https://doaj.org/article/2ff0866500c148c9845f644733c359b9

Altered cerebral blood flow one month after systemic chemotherapy for breast cancer: a prospective study using pulsed arterial spin labeling MRI perfusion.

Authors: Kelly N H Nudelman, Yang Wang, Brenna C McDonald, Susan K Conroy, Dori J Smith, John D West, Darren P O'Neill, Bryan P Schneider, Andrew J Saykin

Source: PLoS ONE, Vol 9, Iss 5, p e96713 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4016018?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ae25152a00ba4166b4cdb9ed6779e69e

Gliovascular transcriptional perturbations in Alzheimer’s disease reveal molecular mechanisms of blood brain barrier dysfunction

Authors: Özkan İş, Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yilmaz, Prabesh Bhattarai, Tulsi Patel, Jeremiah Bergman, Zachary Quicksall, Michael G. Heckman, Frederick Q. Tutor-New, Birsen Can Demirdogen, Launia White, Shunsuke Koga, Vincent Krause, Yasuteru Inoue, Takahisa Kanekiyo, Mehmet Ilyas Cosacak, Nastasia Nelson, Annie J. Lee, Badri Vardarajan, Richard Mayeux, Naomi Kouri, Kaancan Deniz, Troy Carnwath, Stephanie R. Oatman, Laura J. Lewis-Tuffin, Thuy Nguyen, for the Alzheimer’s Disease Neuroimaging Initiative, Minerva M. Carrasquillo, Jonathan Graff-Radford, Ronald C. Petersen, Clifford R. Jr Jack, Kejal Kantarci, Melissa E. Murray, Kwangsik Nho, Andrew J. Saykin, Dennis W. Dickson, Caghan Kizil, Mariet Allen, Nilüfer Ertekin-Taner

Source: Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0f4d86fabcd9496f8761615d7234bc5b

Cholinergic Enhancement of Brain Activation in Mild Cognitive Impairment (MCI) during Episodic Memory Encoding

Authors: Shannon L Risacher, Yang eWang, Heather A Wishart, Laura A Rabin, Laura A Flashman, Brenna C McDonald, John D West, Robert B Santulli, Andrew J Saykin

Source: Frontiers in Psychiatry, Vol 4 (2013)

Subject Terms: Mild Cognitive Impairment, functional magnetic resonance imaging (fMRI), Alzheimer’s disease (AD), episodic encoding, donepezil (Aricept), task-related functional connectivity, Psychiatry, RC435-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00105/full; https://doaj.org/toc/1664-0640

Access URL: https://doaj.org/article/0e68003d2c1b4e8cae385a2dd230cb92

The Role of Apolipoprotein E (APOE) Genotype in Early Mild Cognitive Impairment (E-MCI)

Authors: Shannon L Risacher, Sungeun eKim, Li eShen, Kwangsik eNho, Tatiana eForoud, Robert C Green, Ronald C Petersen, Clifford R Jack, Paul S Aisen, Robert A Koeppe, William J Jagust, Leslie M Shaw, John Q Trojanowski, Michael W Weiner, Andrew J Saykin

Source: Frontiers in Aging Neuroscience, Vol 5 (2013)

Subject Terms: positron emission tomography (PET), Apolipoprotein E (APOE), early mild cognitive impairment (E-MCI), Florbetapir/AV-45/Amyvid, magnetic resonance imaging (MRI), cerebrospinal fluid (CSF), Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fnagi.2013.00011/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/741c2170f57e4083af2dd4da2db59d02

Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel.

Authors: Sungeun Kim, Shanker Swaminathan, Mark Inlow, Shannon L Risacher, Kwangsik Nho, Li Shen, Tatiana M Foroud, Ronald C Petersen, Paul S Aisen, Holly Soares, Jon B Toledo, Leslie M Shaw, John Q Trojanowski, Michael W Weiner, Brenna C McDonald, Martin R Farlow, Bernardino Ghetti, Andrew J Saykin, Alzheimer’s Disease Neuroimaging Initiative (ADNI)

Source: PLoS ONE, Vol 8, Iss 7, p e70269 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3720913?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2c28cd2aca714081832418d4236d540b

Characterizing the role of brain derived neurotrophic factor genetic variation in Alzheimer's disease neurodegeneration.

Authors: Robyn A Honea, Carlos Cruchaga, Rodrigo D Perea, Andrew J Saykin, Jeffrey M Burns, Daniel R Weinberger, Alison M Goate, Alzheimer’s Disease Neuroimaging Initiative (ADNI)

Source: PLoS ONE, Vol 8, Iss 9, p e76001 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24086677/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f1f7f66bbc4a4d45a9dfa182d1be689a