Benchmark of screening markers for KEAP1/NFE2L2 mutations and joint analysis with the K1N2-score

Authors: Christoph Arolt, Andreas H. Scheel, Margaret Dugan, Robert Wild, Vanessa Richartz, Barbara Holz, Johannes Brägelmann, Svenja Wagener-Ryczek, Sabine Merkelbach-Bruse, Juergen Wolf, Reinhard Buettner, Luigi Catanzariti, Matthias Scheffler, Axel M. Hillmer

Source: npj Precision Oncology, Vol 8, Iss 1, Pp 1-6 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/76dc8f63fb394e5b86b259d9d82f8616

Tumour area infiltration and cell count in endoscopic biopsies of therapy-naive upper GI tract carcinomas by QuPath analysis: implications for predictive biomarker testing

Authors: Andreas H. Scheel, Hannah Lamberty, Yuri Tolkach, Florian Gebauer, Birgid Schoemig-Markiefka, Thomas Zander, Reinhard Buettner, Josef Rueschoff, Christiane Josephine Bruns, Wolfgang Schroeder, Alexander Quaas

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/3fa29354b4e7437cae6b5f805d6c5c1a

Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer

Authors: Florian Malchers, Lucia Nogova, Martijn H.A. van Attekum, Lukas Maas, Johannes Brägelmann, Christoph Bartenhagen, Luc Girard, Graziella Bosco, Ilona Dahmen, Sebastian Michels, Clare E. Weeden, Andreas H. Scheel, Lydia Meder, Kristina Golfmann, Philipp Schuldt, Janna Siemanowski, Jan Rehker, Sabine Merkelbach-Bruse, Roopika Menon, Oliver Gautschi, Johannes M. Heuckmann, Elisabeth Brambilla, Marie-Liesse Asselin-Labat, Thorsten Persigehl, John D. Minna, Henning Walczak, Roland T. Ullrich, Matthias Fischer, Hans Christian Reinhardt, Jürgen Wolf, Reinhard Büttner, Martin Peifer, Julie George, Roman K. Thomas

Source: The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)

Subject Terms: Genetics, Oncology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/ef6247e9f6b84dbca5a0844486ed3d80

Overcoming EGFR G724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors

Authors: Jana Fassunke, Fabienne Müller, Marina Keul, Sebastian Michels, Marcel A. Dammert, Anna Schmitt, Dennis Plenker, Jonas Lategahn, Carina Heydt, Johannes Brägelmann, Hannah L. Tumbrink, Yannic Alber, Sebastian Klein, Alena Heimsoeth, Ilona Dahmen, Rieke N. Fischer, Matthias Scheffler, Michaela A. Ihle, Vanessa Priesner, Andreas H. Scheel, Svenja Wagener, Anna Kron, Konrad Frank, Katia Garbert, Thorsten Persigehl, Michael Püsken, Stefan Haneder, Bernhard Schaaf, Ernst Rodermann, Walburga Engel-Riedel, Enriqueta Felip, Egbert F. Smit, Sabine Merkelbach-Bruse, H. Christian Reinhardt, Stefan M. Kast, Jürgen Wolf, Daniel Rauh, Reinhard Büttner, Martin L. Sos

Source: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d0509a8e9f1241e6a692b9bd9e5d0a9b

Physical basis of the ‘magnification rule’ for standardized Immunohistochemical scoring of HER2 in breast and gastric cancer

Authors: Andreas H. Scheel, Frédérique Penault-Llorca, Wedad Hanna, Gustavo Baretton, Peter Middel, Judith Burchhardt, Manfred Hofmann, Bharat Jasani, Josef Rüschoff

Source: Diagnostic Pathology, Vol 13, Iss 1, Pp 1-7 (2018)

Subject Terms: HER2/neu, Immunohistochemistry, Breast cancer, Gastric cancer, Magnification rule, Predictive biomarker, Pathology, RB1-214

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13000-018-0696-x; https://doaj.org/toc/1746-1596

Access URL: https://doaj.org/article/b3325c6ae48c49bd9e0ab7a9cb8b79da

ALK G1269A mutation as a potential mechanism of acquired resistance to crizotinib in an ALK-rearranged inflammatory myofibroblastic tumor

Authors: Sebastian Y. F. Michels, Andreas H. Scheel, Thomas Wündisch, Johannes M. Heuckmann, Roopika Menon, Michael Puesken, Carsten Kobe, Helen Pasternack, Carina Heydt, Matthias Scheffler, Rieke Fischer, Anne M. Schultheis, Sabine Merkelbach-Bruse, Lukas Heukamp, Reinhard Büttner, Jürgen Wolf

Source: npj Precision Oncology, Vol 1, Iss 1, Pp 1-4 (2017)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/33a80232e38044a3a05d9a9bbd74b52a

Oncogenic KRAS Impairs EGFR Antibodies' Efficiency by C/EBPβ-Dependent Suppression of EGFR Expression

Authors: Stefanie Derer, Sven Berger, Martin Schlaeth, Tanja Schneider-Merck, Katja Klausz, Stefan Lohse, Marije B. Overdijk, Michael Dechant, Christian Kellner, Iris Nagelmeier, Andreas H. Scheel, Jeroen J. Lammerts van Bueren, Jan G.J. van de Winkel, Paul W.H.I. Parren, Matthias Peipp, Thomas Valerius

Source: Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 3, Pp 190-205 (2012)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558612800327; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/f35805a210d2477089c2536154f9e1ad