Detection of circulating tumor DNA by tumor-informed whole-genome sequencing enables prediction of recurrence in stage III colorectal cancer patients

Authors: Frydendahl, Amanda, Nors, Jesper, Rasmussen, Mads H., Henriksen, Tenna V., Nesic, Marijana, Reinert, Thomas, Afterman, Danielle, Lauterman, Tomer, Kuzman, Maja, Gonzalez, Santiago, Glavas, Dunja, Smadback, James, Maloney, Dillon, Levatic, Jurica, Yahalom, Michael, Ptashkin, Ryan, Tavassoly, Iman, Donenhirsh, Zohar, White, Eric, Kandasamy, Ravi, Alon, Ury, Nordentoft, Iver, Lindskrog, Sia V., Dyrskjøt, Lars, Jaensch, Claudia, Løve, Uffe S., Andersen, Per V., Thorlacius-Ussing, Ole, Iversen, Lene H., Gotschalck, Kåre A., Zviran, Asaf, Oklander, Boris, Andersen, Claus L.

Source: In European Journal of Cancer November 2024 211

Exploring the biology of ctDNA release in colorectal cancer

Authors: Andersen, Laura, Kisistók, Judit, Henriksen, Tenna V., Bramsen, Jesper B., Reinert, Thomas, Øgaard, Nadia, Mattesen, Trine B., Birkbak, Nicolai J., Andersen, Claus L.

Source: In European Journal of Cancer August 2024 207

Tumour-agnostic circulating tumour DNA analysis for improved recurrence surveillance after resection of colorectal liver metastases: A prospective cohort study

Authors: Øgaard, Nadia, Reinert, Thomas, Henriksen, Tenna V., Frydendahl, Amanda, Aagaard, Emilie, Ørntoft, Mai-Britt W., Larsen, Marie Ø., Knudsen, Anders R., Mortensen, Frank V., Andersen, Claus L.

Source: European journal of cancer. 163:163-176

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155860037.0x000001&indx=1&recIds=ETOCvdc_100155860037.0x000001

Development of blood-based biomarker tests for early detection of colorectal neoplasia: Influence of blood collection timing and handling procedures

Authors: Lech Pedersen, Niels, Mertz Petersen, Mathias, Ladd, Jon J., Lampe, Paul D., Bresalier, Robert S., Davis, Gerard J., Demuth, Christina, Jensen, Sarah Ø., Andersen, Claus L., Ferm, Linnea, Christensen, Ib J., Nielsen, Hans J.

Source: In Clinica Chimica Acta August 2020 507:39-53

CtDNA-guided adjuvant chemotherapy for colorectal cancer—ready for prime time?

Authors: Andersen, Claus L., Heitzer, Ellen

Source: Cancer cell. 40(9):911-913

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172915560.0x000001&indx=1&recIds=ETOCvdc_100172915560.0x000001

The effect of surgical trauma on circulating free DNA levels in cancer patients—implications for studies of circulating tumor DNA

Authors: Henriksen, Tenna V., Reinert, Thomas, Christensen, Emil, Sethi, Himanshu, Birkenkamp‐Demtröder, Karin, Gögenur, Mikail, Gögenur, Ismail, Zimmermann, Bernhard G., Dyrskjøt, Lars, Andersen, Claus L.

Source: Molecular oncology. 14(8):1670-1679

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107597833.0x000001&indx=1&recIds=ETOCvdc_100107597833.0x000001

Beyond basics: Key mutation selection features for successful tumor‐informed ctDNA detection.

Authors: Nesic, Marijana, Rasmussen, Mads H., Henriksen, Tenna V., Demuth, Christina, Frydendahl, Amanda, Nordentoft, Iver, Dyrskjøt, Lars, Andersen, Claus L.

Source: International Journal of Cancer; Sep2024, Vol. 155 Issue 5, p925-933, 9p

Subject Terms: CIRCULATING tumor DNA, BLADDER cancer, GENETIC mutation, SOMATIC mutation, ERROR rates

An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes

Authors: Bekker-Jensen, Dorte B., Kelstrup, Christian D., Batth, Tanveer S., Larsen, Sara C., Haldrup, Christa, Bramsen, Jesper B., Sørensen, Karina D., Høyer, Søren, Ørntoft, Torben F., Andersen, Claus L., Nielsen, Michael L., Olsen, Jesper V.

Source: In Cell Systems 28 June 2017 4(6):587-599

Dynamics of Human DNA Topoisomerases IIα and IIβ in Living Cells

Authors: Christensen, Morten O., Larsen, Morten K., Barthelmes, Hans Ullrich, Hock, Robert, Andersen, Claus L., Kjeldsen, Eigil, Knudsen, Birgitta R., Westergaard, Ole, Boege, Fritz, Mielke, Christian

Source: The Journal of Cell Biology, 2002 Apr 01. 157(1), 31-44.

Access URL: https://www.jstor.org/stable/1620937

SNHG16 is regulated by the Wnt pathway in colorectal cancer and affects genes involved in lipid metabolism

Authors: Christensen, Lise Lotte, True, Kirsten, Hamilton, Mark P., Nielsen, Morten M., Damas, Nkerorema D., Damgaard, Christian K., Ongen, Halit, Dermitzakis, Emmanouil, Bramsen, Jesper B., Pedersen, Jakob S., Lund, Anders H., Vang, Søren, Stribolt, Katrine, Madsen, Mogens R., Laurberg, Søren, McGuire, Sean E., Ørntoft, Torben F., Andersen, Claus L.

Source: In Molecular Oncology October 2016 10(8):1266-1282

Establishment and characterization of models of chemotherapy resistance in colorectal cancer: Towards a predictive signature of chemoresistance

Authors: Jensen, Niels F., Stenvang, Jan, Beck, Mette K., Hanáková, Barbora, Belling, Kirstine C., Do, Khoa N., Viuff, Birgitte, Nygård, Sune B., Gupta, Ramneek, Rasmussen, Mads H., Tarpgaard, Line S., Hansen, Tine P., Budinská, Eva, Pfeiffer, Per, Bosman, Fred, Tejpar, Sabine, Roth, Arnaud, Delorenzi, Mauro, Andersen, Claus L., Rømer, Maria U., Brünner, Nils, Moreira, José M.A.

Source: In Molecular Oncology June 2015 9(6):1169-1185

MethCORR infers gene expression from DNA methylation and allows molecular analysis of ten common cancer types using fresh-frozen and formalin-fixed paraffin-embedded tumor samples

Authors: Mattesen, Trine B., Andersen, Claus L., Bramsen, Jesper B.

Source: Clinical epigenetics. 13(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193303163.0x000001&indx=1&recIds=ETOCvdc_100193303163.0x000001

A Dual Program for Translation Regulation in Cellular Proliferation and Differentiation

Authors: Gingold, Hila, Tehler, Disa, Christoffersen, Nanna R., Nielsen, Morten M., Asmar, Fazila, Kooistra, Susanne M., Christophersen, Nicolaj S., Christensen, Lise Lotte, Borre, Michael, Sørensen, Karina D., Andersen, Lars D., Andersen, Claus L., Hulleman, Esther, Wurdinger, Tom, Ralfkiær, Elisabeth, Helin, Kristian, Grønbæk, Kirsten, Ørntoft, Torben, Waszak, Sebastian M., Dahan, Orna, Pedersen, Jakob Skou, Lund, Anders H., Pilpel, Yitzhak

Source: In Cell 11 September 2014 158(6):1281-1292

Mnk2 Alternative Splicing Modulates the p38-MAPK Pathway and Impacts Ras-Induced Transformation

Authors: Maimon, Avraham, Mogilevsky, Maxim, Shilo, Asaf, Golan-Gerstl, Regina, Obiedat, Akram, Ben-Hur, Vered, Lebenthal-Loinger, Ilana, Stein, Ilan, Reich, Reuven, Beenstock, Jonah, Zehorai, Eldar, Andersen, Claus L., Thorsen, Kasper, Ørntoft, Torben F., Davis, Roger J., Davidson, Ben, Mu, David, Karni, Rotem

Source: In Cell Reports 24 April 2014 7(2):501-513

Putting a brake on stress signaling: miR-625-3p as a biomarker for choice of therapy in colorectal cancer

Authors: Lyskjær, Iben, Rasmussen, Mads H, Andersen, Claus L

Source: Epigenomics. 8(11):1449-1452

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139371086.0x000001&indx=1&recIds=ETOCvdc_100139371086.0x000001

High expression of microRNA-625-3p is associated with poor response to first-line oxaliplatin based treatment of metastatic colorectal cancer

Authors: Rasmussen, Mads H., Jensen, Niels F., Tarpgaard, Line S., Qvortrup, Camilla, Rømer, Maria U., Stenvang, Jan, Hansen, Tine P., Christensen, Lise L., Lindebjerg, Jan, Hansen, Flemming, Jensen, Benny V., Hansen, Torben F., Pfeiffer, Per, Brünner, Nils, Ørntoft, Torben F., Andersen, Claus L.

Source: In Molecular Oncology June 2013 7(3):637-646

MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer

Authors: Mattesen, Trine B., Rasmussen, Mads H., Sandoval, Juan, Ongen, Halit, Árnadóttir, Sigrid S., Gladov, Josephine, Martinez-Cardus, Anna, Castro de Moura, Manuel, Madsen, Anders H., Laurberg, Søren, Dermitzakis, Emmanouil T., Esteller, Manel, Andersen, Claus L., Bramsen, Jesper B.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174611653.0x000001&indx=1&recIds=ETOCvdc_100174611653.0x000001

Publisher Correction: MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer

Authors: Mattesen, Trine B., Rasmussen, Mads H., Sandoval, Juan, Ongen, Halit, Árnadóttir, Sigrid S., Gladov, Josephine, Martinez-Cardus, Anna, de Moura, Manuel Castro, Madsen, Anders H., Laurberg, Søren, Dermitzakis, Emmanouil T., Esteller, Manel, Andersen, Claus L., Bramsen, Jesper B.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174600138.0x000001&indx=1&recIds=ETOCvdc_100174600138.0x000001

Alternative Splicing of SLC39A14 in Colorectal Cancer is Regulated by the Wnt Pathway

Authors: Thorsen, Kasper ^‡, Mansilla, Francisco ^‡, Schepeler, Troels ^‡, Øster, Bodil ^‡, Rasmussen, Mads H. ^‡, Dyrskjøt, Lars ^‡, Karni, Rotem ^§, Akerman, Martin ^¶, Krainer, Adrian R. ^¶, Laurberg, Søren ^‖, Andersen, Claus L. ^‡, Ørntoft, Torben F. ^{‖, **}

Source: In Molecular & Cellular Proteomics January 2011 10(1)

DREAMS: deep read-level error model for sequencing data applied to low-frequency variant calling and circulating tumor DNA detection.

Authors: Christensen, Mikkel H., Drue, Simon O., Rasmussen, Mads H., Frydendahl, Amanda, Lyskjær, Iben, Demuth, Christina, Nors, Jesper, Gotschalck, Kåre A., Iversen, Lene H., Andersen, Claus L., Pedersen, Jakob Skou

Source: Genome Biology; 4/30/2023, Vol. 24 Issue 1, p1-25, 25p