The prostate time bomb.

Authors: Lawton, Graham (AUTHOR)

Source: New Scientist. 8/17/2024, Vol. 263 Issue 2504, p40-43. 4p. 4 Color Photographs.

Subjects: GENETIC risk score, BRCA genes, PROSTATE cancer patients, DIGESTIVE system diseases, BENIGN prostatic hyperplasia, PROSTATE

TREATING PROSTATE CANCER AT ANY STAGE.

Authors: GARNICK, MARC B. (AUTHOR)

Source: Scientific American. May2024, Vol. 330 Issue 5, p66-69. 4p. 1 Diagram.

Subjects: ANDROGEN receptors, PROSTATE cancer, MALE reproductive organs, PROSTATE cancer patients, LYMPHADENECTOMY, POSITRON emission tomography computed tomography, PELVIS

Integrated Bioinformatic Analyses Reveal Thioredoxin as a Putative Marker of Cancer Stem Cells and Prognosis in Prostate Cancer.

Authors: Sugiki, Shigeru¹ (AUTHOR), Horie, Tetsuhiro^2,3 (AUTHOR), Kunii, Kenshiro¹ (AUTHOR), Sakamoto, Takuya^2,3 (AUTHOR), Nakamura, Yuka² (AUTHOR), Chikazawa, Ippei¹ (AUTHOR), Morita, Nobuyo¹ (AUTHOR), Ishigaki, Yasuhito² (AUTHOR), Miyazawa, Katsuhito¹ (AUTHOR) miyazawa@kanazawa-med.ac.jp

Source: Cancer Informatics. 2/24/2025, p1-12. 12p.

Subject Terms: *CANCER stem cells, *PROSTATE cancer prognosis, *RNA sequencing, *TUMOR markers, *PROSTATE cancer

Machine learning-based identification of co-expressed genes in prostate cancer and CRPC and construction of prognostic models.

Authors: Fan, Changhui¹ (AUTHOR), Huang, Zhiheng¹ (AUTHOR) 1011702103@qq.com, Xu, Han² (AUTHOR), Zhang, Tianhe¹ (AUTHOR), Wei, Haiyang¹ (AUTHOR), Gao, Junfeng¹ (AUTHOR), Xu, Changbao¹ (AUTHOR)

Source: Scientific Reports. 2/16/2025, Vol. 15 Issue 1, p1-13. 13p.

Subject Terms: *CASTRATION-resistant prostate cancer, *MEDICAL sciences, *GENE expression, *PROSTATE cancer patients, *PROSTATE-specific antigen

Personalized metronomic radiopharmaceutical therapy through injection profile optimization via physiologically based pharmacokinetic (PBPK) modeling.

Authors: Golzaryan, Aryan¹ (AUTHOR), Soltani, M.^1,2,3,4,5,6 (AUTHOR) msoltani@kntu.ac.ir, Moradi Kashkooli, Farshad¹ (AUTHOR), Saboury, Babak^4,7 (AUTHOR), Rahmim, Arman^4,8 (AUTHOR) arman.rahmim@ubc.ca

Source: Scientific Reports. 2/3/2025, Vol. 15 Issue 1, p1-12. 12p.

Subject Terms: *CASTRATION-resistant prostate cancer, *PROSTATE cancer patients, *ABSORBED dose, *RADIOPHARMACEUTICALS, *RADIOACTIVITY

Exosomal Liquid Biopsy in Prostate Cancer: A Systematic Review of Biomarkers for Diagnosis, Prognosis, and Treatment Response.

Authors: Hamid, Yameen^1,2 (AUTHOR) muhammad.hamid3@nhs.net, Rabbani, Rukhshana Dina³ (AUTHOR) rukhshana.rabbani@nhs.net, Afsara, Rakkan⁴ (AUTHOR) tushiafsararakkan125@gmail.com, Nowrin, Samarea⁵ (AUTHOR) samarea.nowrin@nhs.net, Ghose, Aruni³ (AUTHOR) aruni.ghose1@gmail.com, Papadopoulos, Vasileios⁶ (AUTHOR) vpapadoster@gmail.com, Sirlantzis, Konstantinos⁷ (AUTHOR) konstantinos.sirlantzis@canterbury.ac.uk, Ovsepian, Saak V.^8,9 (AUTHOR) s.v.ovsepian@greenwich.ac.uk, Boussios, Stergios^{3,10,11,12,13} (AUTHOR) stergiosboussios@gmail.com

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p802. 29p.

Subject Terms: *BENIGN prostatic hyperplasia, *PROSTATE cancer prognosis, *PROSTATE cancer patients, *CANCER diagnosis, *PROSTATE-specific antigen

AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate cancer.

Authors: Wang, Hong¹ (AUTHOR), Cui, Chunli² (AUTHOR), Li, Weiyi³ (AUTHOR), Wu, Hui¹ (AUTHOR), Sha, Jianjun¹ (AUTHOR) shajianjun@renji.com, Pan, Jiahua¹ (AUTHOR) panjiahua@renji.com, Xue, Wei¹ (AUTHOR) xuewei@renji.com

Source: Journal of Experimental & Clinical Cancer Research (17569966). 1/14/2025, Vol. 44 Issue 1, p1-19. 19p.

Subject Terms: *CASTRATION-resistant prostate cancer, *MEDICAL sciences, *CANCER stem cells, *CANCER cell proliferation, *PROSTATE cancer patients

The Emerging Predictive and Prognostic Role of Aggressive-Variant-Associated Tumor Suppressor Genes Across Prostate Cancer Stages.

Authors: Pedrani, Martino^1,2 (AUTHOR) martino.pedrani@eoc.ch, Barizzi, Jessica³ (AUTHOR), Salfi, Giuseppe^1,4 (AUTHOR) alessandro.nepote@eoc.ch, Nepote, Alessandro^1,4,5 (AUTHOR) sara.merler@eoc.ch, Testi, Irene^1,6 (AUTHOR) ricardo.pereiramestre@eoc.ch, Merler, Sara^1,4,7,8 (AUTHOR) fabio.turco@eoc.ch, Castelo-Branco, Luis¹ (AUTHOR) silke.gillessen@eoc.ch, Mestre, Ricardo Pereira^1,4 (AUTHOR), Turco, Fabio¹ (AUTHOR), Tortola, Luigi¹ (AUTHOR), Theurillat, Jean-Philippe^4,8 (AUTHOR), Gillessen, Silke^1,8 (AUTHOR), Vogl, Ursula¹ (AUTHOR) ursula.vogl@eoc.ch

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 1, p318. 38p.

Subject Terms: *TUMOR suppressor genes, *PROSTATE cancer prognosis, *GENOMICS, *PROSTATE cancer, *TUMOR classification

Comparative Study on the Application Value of Transperineal Prostate Combined Biopsy and Transrectal Prostate Systematic Biopsy in Diagnosing Prostate Cancer in Patients with Different PSA Zones.

Authors: Hailuo Wang¹, Hao Wang¹, Wen Gao², Peng Xu, Jingkai Wang³, Hao Xu⁴, Deng Pan⁴, Yuyang Ma⁴, Ruoran Zhang³, Peiyong Zhang⁵, Kun Pang^1,5 paking@xzhmu.edu.cn

Source: Urology Journal. Jan/Feb2025, Vol. 22 Issue 1, p37-43. 7p.

Subject Terms: *PROSTATE biopsy, *PROSTATE cancer patients, *PROSTATE-specific antigen, *ENDORECTAL ultrasonography, *PROSTATE cancer, *STATISTICAL significance

The association between dietary acid load and odds of prostate cancer: a case-control study.

Authors: Mehranfar, Sanaz¹ (AUTHOR), Jalilpiran, Yahya^1,2 (AUTHOR), Rahimi, Haleh³ (AUTHOR), Jafari, Alireza¹ (AUTHOR), Setayesh, Leila¹ (AUTHOR), Clark, Cain C. T.⁴ (AUTHOR), Faghih, Shiva⁵ (AUTHOR) shivafaghih@gmail.com

Source: Journal of Health, Population & Nutrition. 3/8/2025, Vol. 44 Issue 1, p1-10. 10p.

Subject Terms: *PROSTATE cancer, *DIET, *DISEASE risk factors, *IRANIANS, *CASE-control method, *ODDS ratio

Non-DRE Voided Urine Test to Diagnose Prostate Cancer: Updated Results.

Authors: Gomella, Patrick T.¹ (AUTHOR) patrick.gomella@jefferson.edu, Leong, Joon Yau^1,2 (AUTHOR), Gomella, Leonard G.^1,3 (AUTHOR), Tomar, Vivek S.^2,4 (AUTHOR), Teran, Hector^1,2 (AUTHOR), Trabulsi, Edouard J.^2,3 (AUTHOR), Thakur, Madhukar L.^3,4 (AUTHOR)

Source: Diagnostics (2075-4418). Mar2025, Vol. 15 Issue 5, p607. 9p.

Subject Terms: *DIGITAL rectal examination, *PROSTATE cancer patients, *PROSTATE-specific antigen, *RADICAL prostatectomy, *CANCER cells

ARv7 promotes the escape of prostate cancer cells from androgen deprivation therapy-induced senescence by mediating the SKP2/p27 axis.

Authors: Zhuang, Dian¹ (AUTHOR), Kang, Jinsong¹ (AUTHOR), Luo, Haoge² (AUTHOR), Tian, Yu¹ (AUTHOR), Liu, Xiaoping¹ (AUTHOR), Shao, Chen³ (AUTHOR) shaochen@jlu.edu.cn

Source: BMC Biology. 2/28/2025, Vol. 23 Issue 1, p1-16. 16p.

Subject Terms: *ANDROGEN deprivation therapy, *CASTRATION-resistant prostate cancer, *MEDICAL sciences, *CELLULAR aging, *CELL cycle

RhoB regulates prostate cancer cell proliferation and docetaxel sensitivity via the PI3K-AKT signaling pathway.

Authors: Sheng, Tiantian¹ (AUTHOR), Su, Hang² (AUTHOR), Yao, Lu³ (AUTHOR), Qu, Zhen¹ (AUTHOR), Liu, Hui¹ (AUTHOR), Shao, Wenjuan⁴ (AUTHOR) Shaowenjuan1022@163.com, Zhang, Xiangyu¹ (AUTHOR) zhangxiangyu666@126.com

Source: BMC Cancer. 2/26/2025, Vol. 25 Issue 1, p1-14. 14p.

Subject Terms: *CASTRATION-resistant prostate cancer, *MEDICAL sciences, *CANCER cell proliferation, *CYTOLOGY, *LIFE sciences

Identification of CSRP1 as novel biomarker for hormone-sensitive prostate cancer by the combination of clinical and functional research.

Authors: Pan, Chenxi¹ (AUTHOR), Wang, Wei² (AUTHOR), He, Yi² (AUTHOR) heyi_gzr@163.com, Yang, Bo² (AUTHOR) yangbo20160101@163.com

Source: Cancer Cell International. 2/24/2025, Vol. 25 Issue 1, p1-16. 16p.

Subject Terms: *MEDICAL sciences, *PROSTATE cancer, *MULTIOMICS, *MEDICAL research, *TUMOR growth

Stereotactic body radiotherapy (SBRT) as a treatment for localized prostate cancer: a retrospective analysis.

Authors: De Cooman, Brecht¹ (AUTHOR) Brecht.De.Cooman@vub.be, Debacker, Tibaut² (AUTHOR), Adams, Thomas³ (AUTHOR), Lamberts, Guy⁴ (AUTHOR), De Troyer, Bart⁵ (AUTHOR), Claessens, Marc⁶ (AUTHOR), De Kerf, Geert⁷ (AUTHOR), Mercier, Carole⁷ (AUTHOR), Dirix, Piet⁷ (AUTHOR), Ost, Piet⁷ (AUTHOR)

Source: Radiation Oncology. 2/21/2025, Vol. 20 Issue 1, p1-11. 11p.

Subject Terms: *EXTERNAL beam radiotherapy, *PROSTATE cancer patients, *SECOND grade (Education), *STEREOTACTIC radiotherapy, *ELECTRONIC health records

LINC00657 exhibits oncogenic properties in prostate cancer and may serve as a prognostic biomarker in cancer.

Authors: Wen, Yaoan¹ (AUTHOR), Zhan, Shuyuan¹ (AUTHOR), Wang, Shenfan² (AUTHOR), Yang, Longjie¹ (AUTHOR), Yang, Siqi¹ (AUTHOR), Zheng, Song¹ (AUTHOR) zhengwu_99@outlook.com

Source: BMC Cancer. 2/21/2025, Vol. 25 Issue 1, p1-9. 9p.

Subject Terms: *PROSTATE cancer prognosis, *MEDICAL sciences, *LINCRNA, *CELL migration, *OVERALL survival

Cell Models of Castration Resistant and High Dose Testosterone-Resistant Prostate Cancer Recapitulate the Heterogeneity of Response Observed in Clinical Practice.

Authors: Graham, Laura S.¹ (AUTHOR) laura.graham@cuanschutz.edu, Su, Lih-Jen¹ (AUTHOR) joseph.petraccione@cuanschutz.edu, Nicklawsky, Andrew² (AUTHOR) andrew.nicklawsky@cuanschutz.edu, Feng, Frances Xiuyan³ (AUTHOR) frances.feng@cuanschutz.edu, Orlicky, David³ (AUTHOR) david.orlicky@cuanschutz.edu, Petraccione, Joseph¹ (AUTHOR) maren.salzmann-sullivan@cuanschutz.edu, Salzmann-Sullivan, Maren¹ (AUTHOR) thomas.flaig@cuanschutz.edu, Nordeen, Steven K.³ (AUTHOR) steve.nordeen@cuanschutz.edu, Flaig, Thomas W.¹ (AUTHOR)

Source: Cancers. Feb2025, Vol. 17 Issue 4, p593. 12p.

Subject Terms: *PROSTATE tumors treatment, *CASTRATION-resistant prostate cancer, *TESTOSTERONE, *ANTIANDROGENS, *BIOLOGICAL models, *IN vitro studies, *DRUG resistance in cancer cells, *RESEARCH funding, *CLINICAL trials, *IN vivo studies, *MICE, *CELL lines, *HORMONE therapy, *DRUG efficacy, *ANIMAL experimentation, *EVALUATION

Circulating Epithelial Tumor Cells (CETC/CTC) in Prostate Cancer: Potential Prognostic Marker for the Risk of Recurrence During Radiotherapy.

Authors: Schott, Dorothea¹ (AUTHOR) dschott@simfo.de, Pizon, Monika^1,2 (AUTHOR), Drozdz, Sonia^2,3 (AUTHOR), Mäurer, Irina^3,4 (AUTHOR), Wurschi, Georg^2,4,5 (AUTHOR), Pachmann, Katharina¹ (AUTHOR), Mäurer, Matthias^2,5 (AUTHOR)

Source: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 4, p1548. 15p.

Subject Terms: *PROSTATE cancer patients, *CANCER-related mortality, *PROGNOSIS, *EPITHELIAL cells, *CANCER radiotherapy

How Standard of Truth Methodology Impacts Diagnostic PSMA-Targeting Radiopharmaceutical Evaluation: Learnings from the Phase 3 SPOTLIGHT Study.

Authors: Lowentritt, Benjamin H.¹ (AUTHOR) blowentritt@chesuro.com, Chau, Albert² (AUTHOR) albert@datacision.co.uk, Davis, Phillip³ (AUTHOR) phillip.davis@blueearthdx.com

Source: Diagnostics (2075-4418). Feb2025, Vol. 15 Issue 4, p473. 9p.

Subject Terms: *STATISTICAL significance, *PROSTATE cancer patients, *PROSTATE-specific antigen, *LYMPH nodes, *CHI-squared test

A multicentre implementation trial of an Artificial Intelligence-driven biomarker to inform Shared decisions for androgen deprivation therapy in men undergoing prostate radiotherapy: the ASTuTE protocol.

Authors: Wegener, Eric^1,2 (AUTHOR) eric.wegener@genesiscare.com, Ng, Michael³ (AUTHOR) michael.ng@genesiscare.com, Guerrieri, Mario³ (AUTHOR) mario.guerrieri@genesiscare.com, Showalter, Timothy N.⁴ (AUTHOR) tim@artera.ai, Leon, Jeremy de⁵ (AUTHOR) jeremy.deleon@genesiscare.com, Ramani, Sagar⁶ (AUTHOR) sagar.ramani@genesiscare.com, Dreosti, Marcus⁷ (AUTHOR) marcus.dreosti@genesiscare.com, Lim, Tee⁸ (AUTHOR) tee.lim@genesiscare.com, Wong, Bradley⁹ (AUTHOR) bradley.wong@genesiscare.com, Chao, Michael¹⁰ (AUTHOR) michael.chao@genesiscare.com, Hogan, Kathryn⁵ (AUTHOR) kathryn.hogan@genesiscare.com, Raman, Avi¹¹ (AUTHOR) aviraman@hotmail.com, McClintock, Scott¹² (AUTHOR) reception@drscottmcclintock.com.au, Foreman, Darren¹³ (AUTHOR) daforeman@me.com, Brown, Matthew¹⁴ (AUTHOR) Matthew.Brown2@health.wa.gov.au, McCombie, Stephen¹⁴ (AUTHOR) Stephen.McCombie@health.wa.gov.au, McMillan, Kevin¹⁵ (AUTHOR) kevinmcmillan@urologyeast.com.au, Beattie, Kieran¹⁶ (AUTHOR) kabeattie@gmail.com, Frydenberg, Mark¹⁷ (AUTHOR) frydenberg@optusnet.com.au, Wong, Lih-Ming¹⁸ (AUTHOR) secretary.ming@melbourneurologygroup.com.au

Source: BMC Cancer. 2/13/2025, Vol. 25 Issue 1, p1-10. 10p.

Subject Terms: *ANDROGEN deprivation therapy, *PROSTATE cancer patients, *MEDICAL sciences, *PROGNOSIS, *ARTIFICIAL intelligence