LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma

Authors: Hamed Alborzinia, Zhiyi Chen, Umut Yildiz, Florencio Porto Freitas, Felix C E Vogel, Julianna Patricia Varga, Jasmin Batani, Christoph Bartenhagen, Werner Schmitz, Gabriele Büchel, Bernhard Michalke, Jashuo Zheng, Svenja Meierjohann, Enrico Girardi, Elisa Espinet, Andrés F Flórez, Ancely Ferreira dos Santos, Nesrine Aroua, Tasneem Cheytan, Julie Haenlin, Lisa Schlicker, Thamara N Xavier da Silva, Adriana Przybylla, Petra Zeisberger, Giulio Superti‐Furga, Martin Eilers, Marcus Conrad, Marietta Fabiano, Ulrich Schweizer, Matthias Fischer, Almut Schulze, Andreas Trumpp, José Pedro Friedmann Angeli

Source: EMBO Molecular Medicine, Vol 15, Iss 8, Pp 1-17 (2023)

Subject Terms: ferroptosis, neuroblastoma, selenocysteine, selenoprotein, synthetic lethality, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/f738f088a5b24d4d84df76ffa09916f9

Glutaminolysis dynamics during astrocytoma progression correlates with tumor aggressiveness

Authors: Yollanda E. Moreira Franco, Maria Jose Alves, Miyuki Uno, Isabele Fattori Moretti, Marina Trombetta-Lima, Suzana de Siqueira Santos, Ancely Ferreira dos Santos, Gabriel Santos Arini, Mauricio S. Baptista, Antonio Marcondes Lerario, Sueli Mieko Oba-Shinjo, Suely Kazue Nagahashi Marie

Source: Cancer & Metabolism, Vol 9, Iss 1, Pp 1-15 (2021)

Subject Terms: Glutaminolysis, GBM, Low-grade astrocytoma, IDH1 mutation, Astrocytoma progression, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2049-3002

Access URL: https://doaj.org/article/29df389030994fb2967580dba96605f2

Troubling bonds: lipid unsaturation promotes selenium dependency and sensitivity to ferroptosis

Authors: Ancély Ferreira dos Santos, José Pedro Friedmann-Angeli

Source: EMBO Molecular Medicine, Vol 16, Iss 11, Pp 2657-2659 (2024)

Subject Terms: Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/ed084cd887e949199580fe0a61344b0e

Thiol starvation triggers melanoma state switching in an ATF4 and NRF2-dependent manner

Authors: Madlen Meinert, Christina Jessen, Anita Hufnagel, Julia Katharina Charlotte Kreß, Mychal Burnworth, Theo Däubler, Till Gallasch, Thamara Nishida Xavier da Silva, Ancély Ferreira dos Santos, Carsten Patrick Ade, Werner Schmitz, Susanne Kneitz, José Pedro Friedmann Angeli, Svenja Meierjohann

Source: Redox Biology, Vol 70, Iss , Pp 103011- (2024)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231723004123; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/3fd2a9cca6cd42a59ae9cc508320c0e7

The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2

Authors: Julia Katharina Charlotte Kreß, Christina Jessen, Anita Hufnagel, Werner Schmitz, Thamara Nishida Xavier da Silva, Ancély Ferreira dos Santos, Laura Mosteo, Colin R. Goding, José Pedro Friedmann Angeli, Svenja Meierjohann

Source: Cell Reports, Vol 42, Iss 7, Pp 112724- (2023)

Subject Terms: CP: Cell biology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723007350; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/e9c771ed6d1c4e52a0f3a51015e08aa6