Intracellular localization of sphingosine kinase 1 alters access to substrate pools but does not affect the degradative fate of sphingosine-1-phosphate[S]

Authors: Deanna L. Siow, Charles D. Anderson, Evgeny V. Berdyshev, Anastasia Skobeleva, Stuart M. Pitson, Binks W. Wattenberg

Source: Journal of Lipid Research, Vol 51, Iss 9, Pp 2546-2559 (2010)

Subject Terms: sphingolipid metabolism, lipid kinase, phosphorylated sphingolipid, sphingosine-1-phosphate lyase, sphingosine, ceramide, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520422850; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/b9694a204b6142418dad7ed55abb33d5

Lipid phosphate phosphohydrolase type 1 (LPP1) degrades extracellular lysophosphatidic acid in vivo.

Authors: Jose L. Tomsig, Ashley H. Snyder, Evgeny V. Berdyshev, Anastasia Skobeleva, Chifundo Mataya, Viswanathan Natarajan, David N. Brindley, Kevin R. Lynch

Source: Biochemical Journal; May2009, Vol. 419 Issue 3, p611-618, 8p

Subject Terms: PHOSPHATASES, LYSOPHOSPHOLIPIDS, LIPIDS, CELL proliferation, CELL growth, WOUND healing, BLOOD platelets