Impacts of PI3K/protein kinase B pathway activation in reactive astrocytes: from detrimental effects to protective functions

Authors: Ramón Pérez-Núñez, María Fernanda González, Ana María Avalos, Lisette Leyton

Source: Neural Regeneration Research, Vol 20, Iss 4, Pp 1031-1041 (2025)

Subject Terms: inflammation, integrins, neuroprotective, neurotoxic, phosphatidylinositol 3-kinase, reactive astrocytes, signal transduction, thy-1 (cd90), Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://journals.lww.com/10.4103/NRR.NRR-D-23-01756; https://doaj.org/toc/1673-5374; https://doaj.org/toc/1876-7958

Access URL: https://doaj.org/article/9126bf4aab634a41a2063a842291be7d

Thy-1 (CD90)-regulated cell adhesion and migration of mesenchymal cells: insights into adhesomes, mechanical forces, and signaling pathways

Authors: Alejandra Valdivia, Ana María Avalos, Lisette Leyton

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: reactive astrocytes, cancer cells, fibroblasts, signal transduction, adhesome, mechanobiology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.1221306/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/773a618e5e2d4e81ad2082ebe3e5ac84

Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis

Authors: Ramón Pérez-Núñez, Alejandro Chamorro, María Fernanda González, Pamela Contreras, Rocío Artigas, Alejandro H. Corvalán, Brigitte van Zundert, Christopher Reyes, Pablo R. Moya, Ana María Avalos, Pascal Schneider, Andrew F. G. Quest, Lisette Leyton

Source: Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)

Subject Terms: Brain damage, Inflammation, Astrogliosis, ALS model, Bioinformatics analysis, PI3K/AKT signaling pathway, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/8f88a252b77145c0982c107e62d40b7f

Thy-1 (CD90)-Induced Metastatic Cancer Cell Migration and Invasion Are β3 Integrin-Dependent and Involve a Ca2+/P2X7 Receptor Signaling Axis

Authors: Marianne Brenet, Samuel Martínez, Ramón Pérez-Nuñez, Leonardo A. Pérez, Pamela Contreras, Jorge Díaz, Ana María Avalos, Pascal Schneider, Andrew F. G. Quest, Lisette Leyton

Source: Frontiers in Cell and Developmental Biology, Vol 8 (2021)

Subject Terms: Thy-1 (CD90), integrin, P2X7R, trans-endothelial migration, breast cancer, melanoma, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2020.592442/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/7837a62594974388907d6aa8a21149c8

Drug resistance phenotypes and genotypes in Mexico in representative gram-negative species: Results from the infivar network.

Authors: Elvira Garza-González, Paola Bocanegra-Ibarias, Miriam Bobadilla-Del-Valle, Luis Alfredo Ponce-de-León-Garduño, Verónica Esteban-Kenel, Jesus Silva-Sánchez, Ulises Garza-Ramos, Humberto Barrios-Camacho, Luis Esaú López-Jácome, Claudia A Colin-Castro, Rafael Franco-Cendejas, Samantha Flores-Treviño, Rayo Morfín-Otero, Fabian Rojas-Larios, Juan Pablo Mena-Ramírez, María Guadalupe Fong-Camargo, Cecilia Teresita Morales-De-la-Peña, Lourdes García-Mendoza, Elena Victoria Choy-Chang, Laura Karina Aviles-Benitez, José Manuel Feliciano-Guzmán, Eduardo López-Gutiérrez, Mariana Gil-Veloz, Juan Manuel Barajas-Magallón, Efren Aguirre-Burciaga, Laura Isabel López-Moreno, Rebeca Thelma Martínez-Villarreal, Jorge Luis Canizales-Oviedo, Carlos Miguel Cetina-Umaña, Daniel Romero-Romero, Fidencio David Bello-Pazos, Nicolás Rogelio Eric Barlandas-Rendón, Joyarib Yanelli Maldonado-Anicacio, Enrique Bolado-Martínez, Mario Galindo-Méndez, Talia Perez-Vicelis, Norma Alavez-Ramírez, Braulio J Méndez-Sotelo, Juan Francisco Cabriales-Zavala, Yirla Citlali Nava-Pacheco, Martha Irene Moreno-Méndez, Ricardo García-Romo, Aldo Rafael Silva-Gamiño, Ana María Avalos-Aguilera, María Asunción Santiago-Calderón, Maribel López-García, María Del Consuelo Velázquez-Acosta, Dulce Isabel Cobos-Canul, María Del Rosario Vázquez-Larios, Ana Elizabeth Ortiz-Porcayo, Arely Elizabeth Guerrero-Núñez, Jazmín Valero-Guzmán, Alina Aracely Rosales-García, Heidy Leticia Ostos-Cantú, Adrián Camacho-Ortiz

Source: PLoS ONE, Vol 16, Iss 3, p e0248614 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0248614&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1faa527b75184017b9f68b5722adcb7c

Connexins in Astrocyte Migration

Authors: Raúl Lagos-Cabré, Francesca Burgos-Bravo, Ana María Avalos, Lisette Leyton

Source: Frontiers in Pharmacology, Vol 10 (2020)

Subject Terms: connexin 43, gap junctions, hemichannels, inflammation, scar-forming astrocytes, reactive astrocytes, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.01546/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/27a057c394314d18919ddd01c8435fc8

Region-Specific Reduction of BDNF Protein and Transcripts in the Hippocampus of Juvenile Rats Prenatally Treated With Sodium Valproate

Authors: Constanza R. Fuentealba, Jenny L. Fiedler, Francisco A. Peralta, Ana María Avalos, Felipe I. Aguayo, Katherine P. Morgado-Gallardo, Esteban E. Aliaga

Source: Frontiers in Molecular Neuroscience, Vol 12 (2019)

Subject Terms: autism, valproate, BDNF, long-3′UTR-bdnf, hippocampus, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnmol.2019.00261/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/798032a72fc843db8a5cabf4124edfd4

Antidepressant-relevant behavioral and synaptic molecular effects of long-term fasudil treatment in chronically stressed male rats

Authors: Luciano Román-Albasini, Gabriela Díaz-Véliz, Felipe Antonio Olave, Felipe Ignacio Aguayo, Gonzalo García-Rojo, Wladimir Antonio Corrales, Juan Pablo Silva, Ana María Ávalos, Paulina S. Rojas, Esteban Aliaga, Jenny Lucy Fiedler

Source: Neurobiology of Stress, Vol 13, Iss , Pp 100234- (2020)

Subject Terms: Fasudil, Chronic stress, Behavior, Hippocampus, Synaptoneurosomes, Antidepressants, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429, Neurophysiology and neuropsychology, QP351-495

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352289520300242; https://doaj.org/toc/2352-2895

Access URL: https://doaj.org/article/b65e996881a24847b82209811b82eefc

IL-17A levels increase in the infarcted region of the left ventricle in a rat model of myocardial infarction

Authors: Ana María Ávalos, Felipe A Apablaza, Mariana Quiroz, Viviana Toledo, Juan Pedro Peña, Luis Michea, Carlos E Irarrazabal, Flavio A Carrión, Fernando E Figueroa

Source: Biological Research, Vol 45, Iss 2, Pp 193-200 (2012)

Subject Terms: Interleukin-17, Th17, myocardial infarction, cardiovascular disease, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000200012; https://doaj.org/toc/0716-9760; https://doaj.org/toc/0717-6287

Access URL: https://doaj.org/article/69ef782e85674ea2ab896db3cc0bca3d

Signaling triggered by Thy-1 interaction with ß3 integrin on astrocytes is an essential step towards unraveling neuronal Thy-1 function

Authors: ANA MARIA AVALOS, CECILIA V. LABRA, ANDREW F.G. QUEST, LISSETTE LEYTON

Source: Biological Research, Vol 35, Iss 2, Pp 231-238 (2002)

Subject Terms: Thy-1 ligand/integrins, GPI-anchored proteins, strocytes, focal adhesion, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200015; https://doaj.org/toc/0716-9760; https://doaj.org/toc/0717-6287

Access URL: https://doaj.org/article/06c406df9d934695a44ea3e4736f5bc4

Early BCR Events and Antigen Capture, Processing and Loading on MHC Class II on B cells

Authors: Ana Maria Avalos, Hidde ePloegh

Source: Frontiers in Immunology, Vol 5 (2014)

Subject Terms: B cell receptor, antigen valency, antigen recognition by BCR, antigen presentation by B cells, B cells as APC, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00092/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a6de70f215284513b1baef5aced78170