Real‐world characteristics and treatment of cardiac transthyretin amyloidosis: A multicentre, observational study

Authors: Richard J. Nies, Svenja Ney, Ingrid Kindermann, Yvonne Bewarder, Angela Zimmer, Fabian Knebel, Katrin Hahn, Sebastian Spethmann, Peter Luedike, Lars Michel, Tienush Rassaf, Maria Papathanasiou, Stefan Störk, Vladimir Cejka, Amin Polzin, Fabian Voss, Malte Kelm, Bernhard Unsöld, Christine Meindl, Michael Paulus, Ali Yilmaz, Bishwas Chamling, Caroline Morbach, Roman Pfister

Source: ESC Heart Failure, Vol 12, Iss 2, Pp 1203-1216 (2025)

Subject Terms: Cardiac amyloidosis, Cardiomyopathy, Heart failure, TTR, Transthyretin, Tafamidis, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5822

Access URL: https://doaj.org/article/39c87cb2fbd84d709642f98d878f8f9a

Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy

Authors: Julius Borger, Elric Zweck, Constanze Moos, Patrick Horn, Fabian Voß, Heinz‐Peter Schultheiss, Jacob Eifer Møller, Udo Boeken, Hug Aubin, Artur Lichtenberg, Malte Kelm, Michael Roden, Amin Polzin, Ralf Westenfeld, Julia Szendroedi, Daniel Scheiber

Source: ESC Heart Failure, Vol 12, Iss 2, Pp 1246-1255 (2025)

Subject Terms: Heart failure, Inflammation, Mitochondria, Reactive oxygen species, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5822

Access URL: https://doaj.org/article/f5c767046c1f44b48c0becbb935eb316

Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure

Authors: Pawel Lisowski, Selene Lickfett, Agnieszka Rybak-Wolf, Carmen Menacho, Stephanie Le, Tancredi Massimo Pentimalli, Sofia Notopoulou, Werner Dykstra, Daniel Oehler, Sandra López-Calcerrada, Barbara Mlody, Maximilian Otto, Haijia Wu, Yasmin Richter, Philipp Roth, Ruchika Anand, Linda A. M. Kulka, David Meierhofer, Petar Glazar, Ivano Legnini, Narasimha Swamy Telugu, Tobias Hahn, Nancy Neuendorf, Duncan C. Miller, Annett Böddrich, Amin Polzin, Ertan Mayatepek, Sebastian Diecke, Heidi Olzscha, Janine Kirstein, Cristina Ugalde, Spyros Petrakis, Sidney Cambridge, Nikolaus Rajewsky, Ralf Kühn, Erich E. Wanker, Josef Priller, Jakob J. Metzger, Alessandro Prigione

Source: Nature Communications, Vol 15, Iss 1, Pp 1-27 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/340c015abcae4c679391b04ea77b6a41

Anthracycline therapy induces an early decline of cardiac contractility in low-risk patients with breast cancer

Authors: Fabian Voß, Fabian Nienhaus, Saskia Pietrucha, Eugen Ruckhäberle, Tanja Fehm, Tobias Melz, Mareike Cramer, Sebastian M. Haberkorn, Ulrich Flögel, Ralf Westenfeld, Daniel Scheiber, Christian Jung, Malte Kelm, Amin Polzin, Florian Bönner

Source: Cardio-Oncology, Vol 10, Iss 1, Pp 1-13 (2024)

Subject Terms: Breast cancer, Anthracyclines, Cardiotoxicity, Myocardial damage, CMR, Diseases of the circulatory (Cardiovascular) system, RC666-701, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2057-3804

Access URL: https://doaj.org/article/2a80ab0f0636410096831446a6099c75

Mitochondrial Creatine Kinase 2 (Ckmt2) as a Plasma-Based Biomarker for Evaluating Reperfusion Injury in Acute Myocardial Infarction

Authors: Alexander Lang, Daniel Oehler, Marcel Benkhoff, Yvonne Reinders, Maike Barcik, Khatereh Shahrjerdi, Madlen Kaldirim, Albert Sickmann, Lisa Dannenberg, Amin Polzin, Susanne Pfeiler, Malte Kelm, Maria Grandoch, Christian Jung, Norbert Gerdes

Source: Biomedicines, Vol 12, Iss 10, p 2368 (2024)

Subject Terms: myocardial infarction, reperfusion injury, mitochondrial damage, biomarker, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/10/2368; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/d1ed960cc82248259f46c1e3484df36f

Sphingosine-1-phosphate suppresses GLUT activity through PP2A and counteracts hyperglycemia in diabetic red blood cells

Authors: Nadine Thomas, Nathalie H. Schröder, Melissa K. Nowak, Philipp Wollnitzke, Shahrooz Ghaderi, Karin von Wnuck Lipinski, Annalena Wille, Jennifer Deister-Jonas, Jens Vogt, Markus H. Gräler, Lisa Dannenberg, Tobias Buschmann, Philipp Westhoff, Amin Polzin, Malte Kelm, Petra Keul, Sarah Weske, Bodo Levkau

Source: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e7bc77bce542466b84c00d135951cee7

Comparison of costs associated with transcatheter mitral valve repair: PASCAL vs MitraClip in a real-world setting

Authors: Jean Marc Haurand, Jafer Haschemi, Daniel Oehler, Yvonne Heinen, Amin Polzin, Malte Kelm, Patrick Horn

Source: BMC Health Services Research, Vol 23, Iss 1, Pp 1-11 (2023)

Subject Terms: Mitral valve regurgitation, Cost comparison, MitraClip, PASCAL, Complications, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1472-6963

Access URL: https://doaj.org/article/20ece8e294744141832570ddc3dd8a00

A comparison of conventional and advanced 3D imaging techniques for percutaneous left atrial appendage closure

Authors: Houtan Heidari, Dominika Kanschik, Oliver Maier, Georg Wolff, Maximilian Brockmeyer, Maryna Masyuk, Raphael Romano Bruno, Amin Polzin, Ralf Erkens, Gerald Antoch, Sebastian Daniel Reinartz, Nikos Werner, Malte Kelm, Tobias Zeus, Shazia Afzal, Christian Jung

Source: Frontiers in Cardiovascular Medicine, Vol 11 (2024)

Subject Terms: left atrial appendage closure, virtual reality, cardiac computed tomography, 3D printing, transesophageal echocardiography, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2024.1328906/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/b9a8951f8cba473a948663f4f92a5130

Influence of Classic and Metabolic Comorbidities on Cmr-derived Myocardial Risk Markers in Patients with St-elevation Myocardial Infarction

Authors: Houtan Heidari, MD, Marie Schäferhoff, Patricia Wischmann, MD, Rojda Ipek, MD, Fabian Nienhaus, Sebastian Haberkorn, Amin Polzin, MD, Christian Jung, MD, Michael Roden, MD, Malte Kelm, MD, Florian Boenner, MD, Mareike Cramer, MD

Source: Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100375- (2024)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1097664724003661; https://doaj.org/toc/1097-6647

Access URL: https://doaj.org/article/e2f20bb714664532a41a69079299dc8c

Elevated t1-relaxation Time in Remote Myocardium After AMI Correlates with Diabetes Mellitus

Authors: Madlen Kaldirim, MD, Rojda Ipek, MD, Houtan Heidari, MD, Amin Polzin, MD, Michael Roden, MD, Florian Bönner, MD, Malte Kelm, MD, Mareike Cramer, MD

Source: Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100379- (2024)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1097664724003703; https://doaj.org/toc/1097-6647

Access URL: https://doaj.org/article/974f88ce7f324daead27d3285a7fb2fd

SYSTEMI - systemic organ communication in STEMI: design and rationale of a cohort study of patients with ST-segment elevation myocardial infarction

Authors: Florian Bönner, Christian Jung, Amin Polzin, Ralf Erkens, Lisa Dannenberg, Rojda Ipek, Madlen Kaldirim, Mareike Cramer, Patricia Wischmann, Oana-Patricia Zaharia, Christian Meyer, Ulrich Flögel, Bodo Levkau, Axel Gödecke, Jens Fischer, Nicolaj Klöcker, Martina Krüger, Michael Roden, Malte Kelm

Source: BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-9 (2023)

Subject Terms: Master Switches, Metabolism, Myocardial ischemia, STEMI, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2261

Access URL: https://doaj.org/article/f6db499aba71485eb415e6f9108a18fd

The Clinical Frailty Scale for mortality prediction of old acutely admitted intensive care patients: a meta-analysis of individual patient-level data

Authors: Raphael Romano Bruno, Bernhard Wernly, Sean M. Bagshaw, Mark van den Boogaard, Jai N. Darvall, Lina De Geer, Pablo Ruiz de Gopegui Miguelena, Daren K. Heyland, David Hewitt, Aluko A. Hope, Emilie Langlais, Pascale Le Maguet, Carmel L. Montgomery, Dimitrios Papageorgiou, Philippe Seguin, Wytske W. Geense, J. Alberto Silva-Obregón, Georg Wolff, Amin Polzin, Lisa Dannenberg, Malte Kelm, Hans Flaatten, Michael Beil, Marcus Franz, Sigal Sviri, Susannah Leaver, Bertrand Guidet, Ariane Boumendil, Christian Jung

Source: Annals of Intensive Care, Vol 13, Iss 1, Pp 1-13 (2023)

Subject Terms: Frailty, Intensive care medicine, Outcome prediction, Systematic review, Individual patient-level data meta-analysis, Elderly, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2110-5820

Access URL: https://doaj.org/article/f73ffebfebed4fd7ae4ab037c0e372fe

Revealing concealed cardioprotection by platelet Mfsd2b-released S1P in human and murine myocardial infarction

Authors: Amin Polzin, Lisa Dannenberg, Marcel Benkhoff, Maike Barcik, Carolin Helten, Philipp Mourikis, Samantha Ahlbrecht, Laura Wildeis, Justus Ziese, Dorothee Zikeli, Daniel Metzen, Hao Hu, Leonard Baensch, Nathalie H. Schröder, Petra Keul, Sarah Weske, Philipp Wollnitzke, Dragos Duse, Süreyya Saffak, Mareike Cramer, Florian Bönner, Tina Müller, Markus H. Gräler, Tobias Zeus, Malte Kelm, Bodo Levkau

Source: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/69086935381d4c428839f590beca54d4

Sphingosine‐1‐phosphate improves outcome of no‐reflow acute myocardial infarction via sphingosine‐1‐phosphate receptor 1

Authors: Amin Polzin, Lisa Dannenberg, Marcel Benkhoff, Maike Barcik, Petra Keul, Aysel Ayhan, Sarah Weske, Samantha Ahlbrecht, Kajetan Trojovsky, Carolin Helten, Sebastian Haberkorn, Ulrich Flögel, Tobias Zeus, Tina Müller, Markus H. Gräler, Malte Kelm, Bodo Levkau

Source: ESC Heart Failure, Vol 10, Iss 1, Pp 334-341 (2023)

Subject Terms: Cardioprotection, LAD‐ligation, Infarct size, Remodelling, Sphingosine‐1‐phosphate, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5822

Access URL: https://doaj.org/article/ff12a4b41a044c2dbe150ec1060b1b94

Platelets Induce Cell Apoptosis of Cardiac Cells via FasL after Acute Myocardial Infarction

Authors: Kim J. Krott, Friedrich Reusswig, Matthias Dille, Evelyn Krüger, Simone Gorressen, Saoussen Karray, Amin Polzin, Malte Kelm, Jens W. Fischer, Margitta Elvers

Source: Biomedicines, Vol 12, Iss 5, p 1077 (2024)

Subject Terms: platelets, myocardial infarction, apoptosis, cardiomyocytes, Fas ligand, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/5/1077; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/60335821fb874b1789797d31e987aa92

Days alive and out of hospital after left ventricular assist device implantation

Authors: Sebastian Roth, René M'Pembele, Alexandra Stroda, Josephine Voit, Giovanna Lurati Buse, Stephan U. Sixt, Ralf Westenfeld, Amin Polzin, Philipp Rellecke, Igor Tudorache, Markus W. Hollmann, Udo Boeken, Payam Akhyari, Artur Lichtenberg, Ragnar Huhn, Hug Aubin

Source: ESC Heart Failure, Vol 9, Iss 4, Pp 2455-2463 (2022)

Subject Terms: Heart failure, Cardiac surgery, Quality of life, Mechanical circulatory support, Patient‐centred outcomes, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5822

Access URL: https://doaj.org/article/9e4c7ccf619c424f89d26f4f6d787a0d

Evaluation of clinical outcomes in patients treated with heparin or direct thrombin inhibitors during extracorporeal membrane oxygenation: a systematic review and meta-analysis

Authors: René M’Pembele, Sebastian Roth, Aljoscha Metzger, Anthony Nucaro, Alexandra Stroda, Amin Polzin, Markus W. Hollmann, Giovanna Lurati Buse, Ragnar Huhn

Source: Thrombosis Journal, Vol 20, Iss 1, Pp 1-19 (2022)

Subject Terms: Bivalirudin, Argatroban, Anticoagulation, Bleeding, Thrombosis, Mechanical circulatory support, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-9560

Access URL: https://doaj.org/article/2e0a78f21ea94137aa3242bcdbf99a0c

Staphylococcus aureus increases platelet reactivity in patients with infective endocarditis

Authors: Amin Polzin, Lisa Dannenberg, René M’Pembele, Philipp Mourikis, David Naguib, Saif Zako, Carolin Helten, Tobias Petzold, Bodo Levkau, Thomas Hohlfeld, Mareike Barth, Tobias Zeus, Stephan Sixt, Ragnar Huhn, Payam Akhyari, Artur Lichtenberg, Malte Kelm, Till Hoffmann

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/205bc71baeb04e69a92b60b45e19829d

Recombinant Acetylcholine Receptor Immunization Induces a Robust Model of Experimental Autoimmune Myasthenia Gravis in Mice

Authors: Lukas Theissen, Christina B. Schroeter, Niklas Huntemann, Saskia Räuber, Vera Dobelmann, Derya Cengiz, Alexander Herrmann, Kathrin Koch-Hölsken, Norbert Gerdes, Hao Hu, Philipp Mourikis, Amin Polzin, Malte Kelm, Hans-Peter Hartung, Sven G. Meuth, Christopher Nelke, Tobias Ruck

Source: Cells, Vol 13, Iss 6, p 508 (2024)

Subject Terms: myasthenia gravis, complement, murine model, experimental autoimmune myasthenia gravis, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/6/508; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/f4973adcbfe1453db7ec94a458ee2aec

Echocardiographic-Fluoroscopic Fusion Imaging Improves Interventionalists’ Learning Curve for Percutaneous Left Atrial Appendage Closure—Initial, Single-Center, Retrospective Observations

Authors: Dominika Kanschik, Houtan Heidari, Kathrin Klein, Amin Polzin, Verena Veulemans, Jürgen Leick, Malte Kelm, Christian Jung, Tobias Zeus, Shazia Afzal

Source: Journal of Cardiovascular Development and Disease, Vol 11, Iss 3, p 82 (2024)

Subject Terms: structural heart diseases, left atrial appendage closure, fusion imaging, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.mdpi.com/2308-3425/11/3/82; https://doaj.org/toc/2308-3425

Access URL: https://doaj.org/article/b708d0c61d454bb7bfc667b71651f3a9