NMNAT2 is a druggable target to drive neuronal NAD production

Authors: James R. Tribble, Melissa Jöe, Carmine Varricchio, Amin Otmani, Alessio Canovai, Baninia Habchi, Evangelia Daskalakis, Romanas Chaleckis, Andrea Loreto, Jonathan Gilley, Craig E. Wheelock, Gauti Jóhannesson, Raymond C. B. Wong, Michael P. Coleman, Andrea Brancale, Pete A. Williams

Source: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/752e0ceae3fe4a6387d7e708ced0fe15

Prophylactic nicotinamide treatment protects from rotenone-induced neurodegeneration by increasing mitochondrial content and volume

Authors: Amin Otmani, Gauti Jóhannesson, Rune Brautaset, James R. Tribble, Pete A. Williams

Source: Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-12 (2024)

Subject Terms: Nicotinamide, Retina, Retina ganglion cells, Mitochondria, Neurodegeneration, Optic nerve, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/c38a73fa7f8049deb758ef1af5f2a4a5

Author Correction: NMNAT2 is a druggable target to drive neuronal NAD production

Authors: James R. Tribble, Melissa Jöe, Carmine Varricchio, Amin Otmani, Alessio Canovai, Baninia Habchi, Evangelia Daskalakis, Romanas Chaleckis, Andrea Loreto, Jonathan Gilley, Craig E. Wheelock, Gauti Jóhannesson, Raymond C. B. Wong, Michael P. Coleman, Andrea Brancale, Pete A. Williams

Source: Nature Communications, Vol 15, Iss 1, Pp 1-2 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/26dff57e67d64561bc637003537e66aa

Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction

Authors: James R. Tribble, Amin Otmani, Shanshan Sun, Sevannah A. Ellis, Gloria Cimaglia, Rupali Vohra, Melissa Jöe, Emma Lardner, Abinaya P. Venkataraman, Alberto Domínguez-Vicent, Eirini Kokkali, Seungsoo Rho, Gauti Jóhannesson, Robert W. Burgess, Peter G. Fuerst, Rune Brautaset, Miriam Kolko, James E. Morgan, Jonathan G. Crowston, Marcela Votruba, Pete A. Williams

Source: Redox Biology, Vol 43, Iss , Pp 101988- (2021)

Subject Terms: Glaucoma, Retina, Retinal ganglion cell, Nicotinamide, Metabolism, Metabolomics, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231721001361; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/11535b7d2b994327966f83eaacbf9faa