Synergistic anticancer effects of cisplatin and phenolic aglycones of the aerial part of Rumex dentatus L. in tongue squamous cell carcinoma: insights from network pharmacology and biological verification

Authors: Amany E. Ragab, Ghada M. Al-Ashmawy, Sherin R. El Afify, Ola A. El-Feky, Amera O. Ibrahim

Source: BMC Complementary Medicine and Therapies, Vol 25, Iss 1, Pp 1-28 (2025)

Subject Terms: Oral Squamous Cell Carcinoma (OSCC), Rumex dentatus L., Cisplatin Resistance, Apoptosis, Cell Cycle Arrest, Network Pharmacology, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/c120c4f50f6b44ef942bacb2d44c1dba

Antidepressants and type 2 diabetes: highways to knowns and unknowns

Authors: Nahi Sabih Alruwaili, Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Ali K. Albuhadily, Amany E. Ragab, Ahmad Awad Alenazi, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batiha

Source: Diabetology & Metabolic Syndrome, Vol 15, Iss 1, Pp 1-14 (2023)

Subject Terms: Type 2 diabetes, Depression, Antidepressants, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://doaj.org/toc/1758-5996

Access URL: https://doaj.org/article/9f28d61343454c0e8ebaef6e4fa73a38

In vitro and in silico β-lactamase inhibitory properties and phytochemical profile of Ocimum basilicum cultivated in central delta of Egypt

Authors: Nagwa A. Shoeib, Lamiaa A. Al-Madboly, Amany E. Ragab

Source: Pharmaceutical Biology, Vol 60, Iss 1, Pp 1969-1980 (2022)

Subject Terms: Methyl cinnamate, antimicrobial, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1388-0209; https://doaj.org/toc/1744-5116

Access URL: https://doaj.org/article/a5fe64c4a5af45abb68ea65e09b57310

Antihyperlipidemic effect of bread fortified with potato peel powder against Triton X-100-induced hyperlipidemia in male albino rats

Authors: Osama I.A. Soltan, Hanaa S.S. Gazwi, Amany E. Ragab, Magda E. Mahmoud, Ferial M.N. Fudllalah, Mesfer M. Alqahtani, Abdulrahman Alasmari, Hesham S. Ghazzawy, Dalia M. Hikal

Source: Journal of Functional Foods, Vol 108, Iss , Pp 105725- (2023)

Subject Terms: Bread, Potato peels, Triton X-100, AMPKα signaling pathway, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1756464623003250; https://doaj.org/toc/1756-4646

Access URL: https://doaj.org/article/fceb6c4dfc484b72b150157442c5c208

Pomegranate peel extract protects against the development of diabetic cardiomyopathy in rats by inhibiting pyroptosis and downregulating LncRNA-MALAT1

Authors: Mariam Ali Abo-Saif, Amany E. Ragab, Amera O. Ibrahim, Othman F. Abdelzaher, Ahmed B. M. Mehanyd, Maha Saber-Ayad, Ola A. El-Feky

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: long non-coding RNA-metastasis-associated lung adenocarcinoma transcript-1, NLRP3, caspase-1, IL1β, TGF-β, pomegranate peel extract, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1166653/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/24ec91116960407f912d6a8c8f89017f

Dietary Olive Leaf Extract Differentially Modulates Antioxidant Defense of Normal and Aeromonas hydrophila-Infected Common Carp (Cyprinus carpio) via Keap1/Nrf2 Pathway Signaling: A Phytochemical and Biological Link

Authors: Doaa H. Assar, Amany E. Ragab, Essam Abdelsatar, Abdallah S. Salah, Shimaa M. R. Salem, Basma M. Hendam, Soad Al Jaouni, Rasha A. Al Wakeel, Marwa F. AbdEl-Kader, Zizy I. Elbialy

Source: Animals, Vol 13, Iss 13, p 2229 (2023)

Subject Terms: olive leaf extract, C. carpio, Aeromonas hydrophila, antioxidant, immunostimulant, gene expression, Veterinary medicine, SF600-1100, Zoology, QL1-991

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2615/13/13/2229; https://doaj.org/toc/2076-2615

Access URL: https://doaj.org/article/58d5a301200043f8bc9167ccd2609439

Assessment of Bioactive Phytochemicals and Utilization of Rosa canina Fruit Extract as a Novel Natural Antioxidant for Mayonnaise

Authors: Osama I. A. Soltan, Hanaa S. S. Gazwi, Amany E. Ragab, Abdullah S. M. Aljohani, Ibrahim M. El-Ashmawy, Gaber El-Saber Batiha, Amin A. Hafiz, Sanaa M. Abdel-Hameed

Source: Molecules, Vol 28, Iss 8, p 3350 (2023)

Subject Terms: Rosa canina fruit extract, GC–MS, HLPC, shelf life, mayonnaise, sensory evaluation, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/28/8/3350; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/f2dbb2ec651f4a0f85fb3153fa23bed5

Evaluation of Zamia floridana A. DC. Leaves and Its Isolated Secondary Metabolites as Natural Anti-Toxoplasma and Anti-Cancer Agents Using In Vitro and In Silico Studies

Authors: Hosam M. El-Seadawy, Kamilia A. Abo El-Seoud, Mona El-Aasr, Haytham O. Tawfik, Wagdy M. Eldehna, Amany E. Ragab

Source: Metabolites, Vol 13, Iss 1, p 10 (2022)

Subject Terms: Zamia floridana, toxoplasmosis, cytotoxicity, in silico docking, bioflavonoids, phenolic acid derivatives, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-1989/13/1/10; https://doaj.org/toc/2218-1989

Access URL: https://doaj.org/article/3b634da1aab045e883572eb623a91e4d

Phytochemical Profile of the Ethanol Extract of Malvaviscus arboreus Red Flower and Investigation of the Antioxidant, Antimicrobial, and Cytotoxic Activities

Authors: Hanaa S. S. Gazwi, Nagwa A. Shoeib, Magda E. Mahmoud, Osama I. A. Soltan, Moaz M. Hamed, Amany E. Ragab

Source: Antibiotics, Vol 11, Iss 11, p 1652 (2022)

Subject Terms: Malvaviscus arboreus, GC-MS, HPLC, antimicrobial, antioxidant, HepG2, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/11/11/1652; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/c774443620fb453588f1827dd3a7da77

Toxoplasmocidal and Cytotoxic Activities Guided Isolation and Characterization of an Undescribed Bioflavonoid-di-C-glucoside from Cycas rumphii Miq. Cultivated in Egypt

Authors: Hosam M. El-Seadawy, Kamilia A. Abo El-Seoud, Mona El-Aasr, Haytham O. Tawfik, Amany E. Ragab

Source: Plants, Vol 11, Iss 21, p 2867 (2022)

Subject Terms: Cycas rumphii, Cycadaceae, toxoplasmosis, cytotoxicity, phenolic acid, biflavonoids, Botany, QK1-989

File Description: electronic resource

Relation: https://www.mdpi.com/2223-7747/11/21/2867; https://doaj.org/toc/2223-7747

Access URL: https://doaj.org/article/288bc777d24949c2b2193908e25abad2

Unravelling the In Vitro and In Vivo Anti-Helicobacter pylori Effect of Delphinidin-3-O-Glucoside Rich Extract from Pomegranate Exocarp: Enhancing Autophagy and Downregulating TNF-α and COX2

Authors: Amany E. Ragab, Lamiaa A. Al-Madboly, Ghada M. Al-Ashmawy, Maha Saber-Ayad, Mariam A. Abo-Saif

Source: Antioxidants, Vol 11, Iss 9, p 1752 (2022)

Subject Terms: Pomegranate, anthocyanin, H. pylori, Malondialdehyde, catalase, TNF-α, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/11/9/1752; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/6a56080788b248eca9f9124f39579369

In Vitro Characterization of Inhibitors for Lung A549 and Leukemia K562 Cell Lines from Fungal Transformation of Arecoline Supported by In Silico Docking to M3-mAChR and ADME Prediction

Authors: Amany E. Ragab, Ebtisam T. Badawy, Shaimaa M. Aboukhatwa, Amal Kabbash, Kamilia A. Abo El-Seoud

Source: Pharmaceuticals, Vol 15, Iss 10, p 1171 (2022)

Subject Terms: arecoline, fungal transformation, lung A549, leukemia K562, apoptosis, M3-mAChR, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/15/10/1171; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/25039111d1544ad69c1bc201143c122f

Biotransformation of Modified Benzylisoquinoline Alkaloids: Boldine and Berberine and In Silico Molecular Docking Studies of Metabolites on Telomerase and Human Protein Tyrosine Phosphatase 1B

Authors: Duaa Eliwa, Abdel-Rahim S. Ibrahim, Amal Kabbash, Mona El-Aasr, Michał Tomczyk, Yousef A. Bin Jardan, Gaber El-Saber Batiha, Amany E. Ragab

Source: Pharmaceuticals, Vol 15, Iss 10, p 1195 (2022)

Subject Terms: biotransformation, boldine, berberine, Cunninghamella elegans NRRL 2310, Rhodotorula rubra NRRL y1592, Penicillium chrysogeneum ATCC 10002, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/15/10/1195; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/809700e40610477aa7c6ea74db69f6f7

Purification, Characterization, Identification, and Anticancer Activity of a Circular Bacteriocin From Enterococcus thailandicus

Authors: Lamiaa A. Al-Madboly, Nehal M. El-Deeb, Amal Kabbash, Manal A. Nael, Ahmed M. Kenawy, Amany E. Ragab

Source: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

Subject Terms: purification, circular, bacteriocin, anticancer, protein sequence, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fbioe.2020.00450/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/699c9a61211a4875a33fb47645b6b2b8

Promising Antiviral Activity of Agrimonia pilosa Phytochemicals against Severe Acute Respiratory Syndrome Coronavirus 2 Supported with In Vivo Mice Study

Authors: Nashwah G. M. Attallah, Aya H. El-Kadem, Walaa A. Negm, Engy Elekhnawy, Thanaa A. El-Masry, Elshaymaa I. Elmongy, Najla Altwaijry, Ashwag S. Alanazi, Gadah Abdulaziz Al-Hamoud, Amany E. Ragab

Source: Pharmaceuticals, Vol 14, Iss 12, p 1313 (2021)

Subject Terms: ALI, immunomodulatory, LPS, LC-ESI-MS/MS, plaque reduction, SARS-CoV-2, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/14/12/1313; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/2429b3d53cd746c89e0f3e79b6e049f3

Stress-Based Production, and Characterization of Glutathione Peroxidase and Glutathione S-Transferase Enzymes From Lactobacillus plantarum

Authors: Lamiaa A. Al-Madboly, Safaa M. Ali, Esmail M. El Fakharany, Amany E. Ragab, Eman G. Khedr, Khaled M. Elokely

Source: Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)

Subject Terms: Lactobacillus plantarum, glutathione s-transferase, glutathione-peroxidase, enzymatic activity, purification, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fbioe.2020.00078/full; https://doaj.org/toc/2296-4185

Access URL: https://doaj.org/article/4c0c4f84460440efaa3bda8e5918f6da

Ameliorative Effects of Aspergillus awamori against the Initiation of Hepatocarcinogenesis Induced by Diethylnitrosamine in a Rat Model: Regulation of Cyp19 and p53 Gene Expression

Authors: Doaa H. Assar, Abd-Allah A. Mokhbatly, Emad W. Ghazy, Amany E. Ragab, Samah Abou Asa, Walied Abdo, Zizy I. Elbialy, Nora Elbialy Mohamed, Ali H. El-Far

Source: Antioxidants, Vol 10, Iss 6, p 922 (2021)

Subject Terms: diethylnitrosamine, hepatocellular carcinoma, Aspergillus awamori, antioxidant, UPLC-PDA-MS/MS, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/10/6/922; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/6dc1c6dc0ed643d3b48a9d7b04e7aaa3

Microbial Oxidation of the Fusidic Acid Side Chain by Cunninghamella echinulata

Authors: Abdel-Rahim S. Ibrahim, Khaled M. Elokely, Daneel Ferreira, Amany E. Ragab

Source: Molecules, Vol 23, Iss 4, p 970 (2018)

Subject Terms: fusidic acid, Cunninghamella echinulata, C-26-oxidation, C-27-oxidation, Organic chemistry, QD241-441

File Description: electronic resource

Relation: http://www.mdpi.com/1420-3049/23/4/970; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/b22fbb39d59545c68d118c4f65606a35