Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses

Authors: Malonis, Ryan J., Earnest, James T., Kim, Arthur S., Angeliadis, Matthew, Holtsberg, Frederick W., Aman, M. Javad, Jangra, Rohit K., Chandran, Kartik, Daily, Johanna P., Diamond, Michael S., Kielian, Margaret, Lai, Jonathan R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Sep . 118(37), 1-11.

Access URL: https://www.jstor.org/stable/27075766

Therapy for Argentine hemorrhagic fever in nonhuman primates with a humanized monoclonal antibody

Authors: Zeitlin, Larry, Cross, Robert W., Geisbert, Joan B., Borisevich, Viktoriya, Agans, Krystle N., Prasad, Abhishek N., Enterlein, Sven, Aman, M. Javad, Bornholdt, Zachary A., Brennan, Miles B., Campbell, Lioudmila, Kim, Do, Mlakar, Neil, Moyer, Crystal L., Pauly, Michael H., Shestowsky, William, Whaley, Kevin J., Fenton, Karla A., Geisbert, Thomas W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar . 118(11), 1-8.

Access URL: https://www.jstor.org/stable/27027616

Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies.

Authors: Wirchnianski, Ariel S.^1,2, Nyakatura, Elisabeth K.¹, Herbert, Andrew S.^3,4, andrew.s.herbert4.civ@health.mil, Kuehne, Ana I.³, Abbasi, Shawn A.^3,4, Florez, Catalina^3,4, Storm, Nadia⁵, McKay, Lindsay G. A.⁵, Dailey, Leandrew¹, Kuang, Erin⁴, Abelson, Dafna M.⁴, Wec, Anna Z.², Chakraborti, Srinjoy¹, Holtsberg, Frederick W.⁶, Shulenin, Sergey⁶, Bornholdt, Zachary A.⁷, Aman, M. Javad⁷, Honko, Anna N.⁴, Griffiths, Anthony⁴, Dye, John M.³

Source: PLoS Pathogens; 4/11/2024, Vol. 20 Issue 4, p1-25, 25p

The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection

Authors: Imre, Gergely, Krähling, Verena, Eichler, Madeleine, Trautmann, Sandra, Ferreirós, Nerea, Aman, M. Javad, Kashanchi, Fatah, Rajalingam, Krishnaraj, Pöhlmann, Stefan, Becker, Stephan, Meyer zu Heringdorf, Dagmar, Pfeilschifter, Josef

Source: In iScience 23 April 2021 24(4)

Potent Neutralization of Staphylococcal Enterotoxin B In Vivo by Antibodies that Block Binding to the T-Cell Receptor

Authors: Chen, Gang, Karauzum, Hatice, Long, Hua, Carranza, Danielle, Holtsberg, Frederick W., Howell, Katie A., Abaandou, Laura, Zhang, Bojie, Jarvik, Nick, Ye, Wei, Liao, Grant C., Gross, Michael L., Leung, Daisy W., Amarasinghe, Gaya K., Aman, M. Javad, Sidhu, Sachdev S.

Source: In Journal of Molecular Biology 4 October 2019 431(21):4354-4367

Ebola Virus VP40 Modulates Cell Cycle and Biogenesis of Extracellular Vesicles

Authors: Pleet, Michelle L., Erickson, James, DeMarino, Catherine, Barclay, Robert A., Cowen, Maria, Lepene, Benjamin, Liang, Janie, Kuhn, Jens H., Prugar, Laura, Stonier, Spencer W., Dye, John M., Zhou, Weidong, Liotta, Lance A., Aman, M. Javad, Kashanchi, Fatah

Source: The Journal of Infectious Diseases, 2018 Dec . 218, S365-S387.

Access URL: https://www.jstor.org/stable/26576203

Efficacy of Ebola Glycoprotein-Specific Equine Polyclonal Antibody Product Against Lethal Ebola Virus Infection in Guinea Pigs

Authors: Chan, Mable, Holtsberg, Frederick W., Vu, Hong, Howell, Katie A., Leung, Anders, Van der Hart, Evelyn, Walz, Paul H., Aman, M. Javad, Kodihalli, Shantha, Kobasa, Darwyn

Source: The Journal of Infectious Diseases, 2018 Dec . 218, S603-S611.

Access URL: https://www.jstor.org/stable/26576233

Role of Antibodies in Protection Against Ebola Virus in Nonhuman Primates Immunized With Three Vaccine Platforms

Authors: Warfield, Kelly L., Howell, Katie A., Vu, Hong, Geisbert, Joan, Wong, Gary, Shulenin, Sergey, Sproule, Stephanie, Holtsberg, Frederick W., Leung, Daisy W., Amarasinghe, Gaya K., Swenson, Dana L., Bavari, Sina, Kobinger, Gary P., Geisbert, Thomas W., Aman, M. Javad

Source: The Journal of Infectious Diseases, 2018 Dec . 218, S553-S564.

Access URL: https://www.jstor.org/stable/26576226

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

Authors: Saphire, Erica Ollmann, Schendel, Sharon L., Fusco, Marnie L., Gangavarapu, Karthik, Gunn, Bronwyn M., Wec, Anna Z., Halfmann, Peter J., Brannan, Jennifer M., Herbert, Andrew S., Qiu, Xiangguo, Wagh, Kshitij, He, Shihua, Giorgi, Elena E., Theiler, James, Pommert, Kathleen B.J., Krause, Tyler B., Turner, Hannah L., Murin, Charles D., Pallesen, Jesper, Davidson, Edgar, Ahmed, Rafi, Aman, M. Javad, Bukreyev, Alexander, Burton, Dennis R., Crowe, James E., Jr., Davis, Carl W., Georgiou, George, Krammer, Florian, Kyratsous, Christos A., Lai, Jonathan R., Nykiforuk, Cory, Pauly, Michael H., Rijal, Pramila, Takada, Ayato, Townsend, Alain R., Volchkov, Viktor, Walker, Laura M., Wang, Cheng-I., Zeitlin, Larry, Doranz, Benjamin J., Ward, Andrew B., Korber, Bette, Kobinger, Gary P., Andersen, Kristian G., Kawaoka, Yoshihiro, Alter, Galit, Chandran, Kartik, Dye, John M.

Source: In Cell 9 August 2018 174(4):938-952

Design and evaluation of bi- and trispecific antibodies targeting multiple filovirus glycoproteins

Authors: Nyakatura, Elisabeth K., Zak, Samantha E., Wec, Anna Z., Hofmann, Daniel, Shulenin, Sergey, Bakken, Russell R., Aman, M. Javad, Chandran, Kartik, Dye, John M., Lai, Jonathan R.

Source: In Journal of Biological Chemistry 20 April 2018 293(16):6201-6211

Antigenic landscapes on Staphylococcus aureus pore-forming toxins reveal insights into specificity and cross-neutralization

Authors: Kailasan, Shweta, Kant, Ravi, Noonan-Shueh, Madeleine, Kanipakala, Tulasikumari, Liao, Grant, Shulenin, Sergey, Leung, Daisy W., Alm, Richard A., Adhikari, Rajan P., Amarasinghe, Gaya K., Gross, Michael L., Aman, M. Javad

Source: MAbs. 14(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168255968.0x000001&indx=1&recIds=ETOCvdc_100168255968.0x000001

Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries

Authors: Yuan, Tom Z., Garg, Pankaj, Wang, Linya, Willis, Jordan R., Kwan, Eric, Hernandez, Ana G Lujan, Tuscano, Emily, Sever, Emily N., Keane, Erica, Soto, Cinque, Mucker, Eric M., Fouch, Mallorie E., Davidson, Edgar, Doranz, Benjamin J., Kailasan, Shweta, Aman, M. Javad, Li, Haoyang, Hooper, Jay W., Saphire, Erica Ollmann, Crowe, James E., Liu, Qiang, Axelrod, Fumiko, Sato, Aaron K.

Source: MAbs. 14(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168255949.0x000001&indx=1&recIds=ETOCvdc_100168255949.0x000001

Ebola Virus-like Particles Protect from Lethal Ebola Virus Infection

Authors: Warfield, Kelly L., Bosio, Catharine M., Welcher, Brent C., Deal, Emily M., Mohamadzadeh, Mansour, Schmaljohn, Alan, Aman, M. Javad, Bavari, Sina

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Dec . 100(26), 15889-15894.

Access URL: https://www.jstor.org/stable/3149101

In vivo Oligomerization and Raft Localization of Ebola Virus Protein VP40 during Vesicular Budding

Authors: Panchal, Rekha G., Ruthel, Gordon, Kenny, Tara A., Kallstrom, George H., Lane, Douglas, Badie, Shirin S., Li, Limin, Bavari, Sina, Aman, M. Javad

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Dec . 100(26), 15936-15941.

Access URL: https://www.jstor.org/stable/3149109

Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability

Authors: Zhao, Xuelian, Howell, Katie A., He, Shihua, Brannan, Jennifer M., Wec, Anna Z., Davidson, Edgar, Turner, Hannah L., Chiang, Chi-I., Lei, Lin, Fels, J. Maximilian, Vu, Hong, Shulenin, Sergey, Turonis, Ashley N., Kuehne, Ana I., Liu, Guodong, Ta, Mi, Wang, Yimeng, Sundling, Christopher, Xiao, Yongli, Spence, Jennifer S., Doranz, Benjamin J., Holtsberg, Frederick W., Ward, Andrew B., Chandran, Kartik, Dye, John M., Qiu, Xiangguo, Li, Yuxing, Aman, M. Javad

Source: In Cell 18 May 2017 169(5):891-904

Dry and liquid formulations of IBT-V02, a novel multi-component toxoid vaccine, are effective against Staphylococcus aureus isolates from low-to-middle income countries.

Authors: Yu Wang, Mukherjee, Ipsita, Venkatasubramaniam, Arundhathi, Dikeman, Dustin, Orlando, Nicholas, Jing Zhang, Ortines, Roger, Mednikov, Mark, Sherchand, Shardulendra P., Kanipakala, Tulasikumari, Thao Le, Shukla, Sanjay, Ketner, Mark, Adhikari, Rajan P., Karauzum, Hatice, Aman, M. Javad, Archer, Nathan K.

Source: Frontiers in Immunology; 2024, p1-15, 15p

Subject Terms: STAPHYLOCOCCUS aureus, SOFT tissue infections, SURGICAL site infections, OSTEOMYELITIS, METHICILLIN-resistant staphylococcus aureus, RABBIT diseases, VACCINES

Geographic Terms: CONGO (Democratic Republic), PALESTINE, CAMBODIA

Functional Cleavage of the Common Cytokine Receptor γ Chain (γ c ) by Calpain

Authors: Noguchi, Masayuki, Sarin, Apurva, Aman, M. Javad, Nakajima, Hiroshi, Shores, Elizabeth W., Henkart, Pierre A., Leonard, Warren J.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1997 Oct . 94(21), 11534-11539.

Access URL: https://www.jstor.org/stable/43320

Protective efficacy of a novel alpha hemolysin subunit vaccine (AT62) against Staphylococcus aureus skin and soft tissue infections

Authors: Adhikari, Rajan P., Thompson, Christopher D., Aman, M. Javad, Lee, Jean C.

Source: In Vaccine 7 December 2016 34(50):6402-6407

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

Authors: Howell, Katie A., Qiu, Xiangguo, Brannan, Jennifer M., Bryan, Christopher, Davidson, Edgar, Holtsberg, Frederick W., Wec, Anna Z., Shulenin, Sergey, Biggins, Julia E., Douglas, Robin, Enterlein, Sven G., Turner, Hannah L., Pallesen, Jesper, Murin, Charles D., He, Shihua, Kroeker, Andrea, Vu, Hong, Herbert, Andrew S., Fusco, Marnie L., Nyakatura, Elisabeth K., Lai, Jonathan R., Keck, Zhen-Yong, Foung, Steven K.H., Saphire, Erica Ollmann, Zeitlin, Larry, Ward, Andrew B., Chandran, Kartik, Doranz, Benjamin J., Kobinger, Gary P., Dye, John M., Aman, M. Javad

Source: In Cell Reports 17 May 2016 15(7):1514-1526

A "Trojan horse" bispecific-antibody strategy for broad protection against ebolaviruses

Authors: Wec, Anna Z., Nyakatura, Elisabeth K., Herbert, Andrew S., Howell, Katie A., Holtsberg, Frederick W., Bakken, Russell R., Mittler, Eva, Christin, John R., Shulenin, Sergey, Jangra, Rohit K., Bharrhan, Sushma, Kuehne, Ana I., Bornholdt, Zachary A., Flyak, Andrew I., Saphire, Erica Ollmann, Crowe, James E., Aman, M. Javad, Dye, John M., Lai, Jonathan R., Chandran, Kartik

Source: Science, 2016 Oct . 354(6310), 350-354.

Access URL: https://www.jstor.org/stable/44710847