Taxifolin mitigates cisplatin-induced testicular damage by reducing inflammation, oxidative stress, and apoptosis in mice

Authors: Al-Khawalde, Alayn' Al-marddyah A. ^a, Abukhalil, Mohammad H. ^{a, b, ⁎}, Althunibat, Osama Y. ^{a, c}, Jaber, Fatima A. ^d, Alaryani, Fatima S. ^d, Saleh, Alaa M. ^e, Albalawi, Aishah E. ^f, Alhasani, Reem H. ^g

Source: In Tissue and Cell April 2025 93

Potential Antimicrobial Activity of Marine Sponge Neopetrosia exigua

Authors: Majali, Ibrahim, Qaralleh, Haitham N., Idid, Syed Z., Saad, Shahbudin, Susanti, Deny, Althunibat, Osama Y.

Source: J Basic Appl Res, 2019, 1(1), 1-13

Subject Terms: Quantitative Biology - Biomolecules

Access URL: http://arxiv.org/abs/1912.05323

Taxifolin Protects Against 5-Fluorouracil-Induced Cardiotoxicity in Mice Through Mitigating Oxidative Stress, Inflammation, and Apoptosis: Possible Involvement of Sirt1/Nrf2/HO-1 Signaling.

Authors: Abukhalil, Mohammad H., Al-Alami, Zina, Alfwuaires, Manal A., Imran, Mohd Rasheeduddin, Aladaileh, Saleem H., Althunibat, Osama Y.

Source: Cardiovascular Toxicology; Mar2025, Vol. 25 Issue 3, p455-470, 16p

Subject Terms: NITRIC-oxide synthases, HEART injuries, LACTATE dehydrogenase, TROPONIN I, SUPEROXIDE dismutase

Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell death in rats

Authors: Althunibat, Osama Y., Abduh, Maisa Siddiq, Abukhalil, Mohammad H., Aladaileh, Saleem H., Hanieh, Hamza, Mahmoud, Ayman M.

Source: In Biomedicine & Pharmacotherapy May 2022 149

Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats

Authors: Abukhalil, Mohammad H., Althunibat, Osama Y., Aladaileh, Saleem H., Al-Amarat, Wesam, Obeidat, Heba M., Al-khawalde, Alayn' Al-marddyah A., Hussein, Omnia E., Alfwuaires, Manal A., Algefare, Abdulmohsen I., Alanazi, Khalid M., Al-Swailmi, Farhan K., Arab, Hany H., Mahmoud, Ayman M.

Source: In Biomedicine & Pharmacotherapy June 2021 138

The impact of weight loss diet programs on anemia, nutrient deficiencies, and organ dysfunction markers among university female students: A cross-sectional study.

Authors: Althunibat, Osama Y.¹ Osama.y.althunibat@ahu.edu.jo, Saghir, Sultan Ayesh Mohammed¹, Aladaileh, Saleem Hmoud^1,2, Rawadieh, Atikah¹

Source: Electronic Journal of General Medicine. Feb2023, Vol. 20 Issue 1, p1-11. 11p.

Subject Terms: *COLLEGE students, *FOOD habits, *REGULATION of body weight, *EVALUATION of human services programs, *CROSS-sectional method, *MULTIPLE organ failure, *RISK assessment, *WEIGHT loss, *MALNUTRITION, *QUESTIONNAIRES, *CHI-squared test, *RESEARCH funding, *IRON deficiency anemia, *BLOOD testing, *BODY mass index, *HEALTH promotion, *DISEASE risk factors

Fisetin ameliorates oxidative stress, inflammation and apoptosis in diabetic cardiomyopathy

Authors: Althunibat, Osama Y., Al Hroob, Amir M., Abukhalil, Mohammad H., Germoush, Mousa O., Bin-Jumah, May, Mahmoud, Ayman M.

Source: In Life Sciences 15 March 2019 221:83-92

Rosmarinic Acid Attenuates Testicular Damage via Modulating Oxidative Stress and Apoptosis in Streptozotocin-Induced Diabetic Albino Mice.

Authors: Al-khawaldeh, Omar, Al-Alami, Zina M., Althunibat, Osama Y., Abuamara, Tamer M. M., Mihdawi, Afnan, Abukhalil, Mohammad H.

Source: Stresses; Sep2024, Vol. 4 Issue 3, p505-517, 13p

Subject Terms: ROSMARINIC acid, OXIDATIVE stress, STREPTOZOTOCIN, REACTIVE oxygen species, APOPTOSIS

Distribution and association of weight-loss diet programs with body mass index and health status among students at Al-Hussein Bin Talal University, Jordan.

Authors: Althunibat, Osama Y.¹, Mohammed Saghir, Sultan Ayesh¹ sultan_a1976@yahoo.com, Aladaileh, Saleem Hmoud¹, Alrawadeh, Atika¹, Al-Areefi, Mahmoud², Alghonmeen, Reham D.¹, Alkhawaldeh, Alayn Al-Marddyah A.¹, Obaidat, Heba M.¹

Source: Electronic Journal of General Medicine. Dec2022, Vol. 19 Issue 6, p1-9. 9p.

Subject Terms: *COLLEGE students, *CROSS-sectional method, *RESEARCH methodology, *HEALTH status indicators, *DIET therapy, *WEIGHT loss, *QUESTIONNAIRES, *DESCRIPTIVE statistics, *BODY mass index, *DATA analysis software, *HEALTH promotion

Geographic Terms: JORDAN

Cardioprotective Effect of Taxifolin against Isoproterenol-Induced Cardiac Injury through Decreasing Oxidative Stress, Inflammation, and Cell Death, and Activating Nrf2/HO-1 in Mice.

Authors: Obeidat, Heba M.¹ (AUTHOR), Althunibat, Osama Y.¹ (AUTHOR), Alfwuaires, Manal A.² (AUTHOR), Aladaileh, Saleem H.^1,3 (AUTHOR), Algefare, Abdulmohsen I.² (AUTHOR), Almuqati, Afaf F.⁴ (AUTHOR), Alasmari, Fawaz⁵ (AUTHOR), Aldal'in, Hammad Khalifeh⁶ (AUTHOR), Alanezi, Abdulkareem A.⁷ (AUTHOR), Alsuwayt, Bader³ (AUTHOR), Abukhalil, Mohammad H.^1,8 (AUTHOR) mabukhalil@ahu.edu.jo

Source: Biomolecules (2218-273X). Nov2022, Vol. 12 Issue 11, p1546. 16p.

Subject Terms: *CELL death, *HEART injuries, *OXIDATIVE stress, *MYOCARDIAL injury, *TROPONIN I, *PYROPTOSIS

Anti-MRSA and cytotoxic activities of different solvent extracts from Artemisia herba-alba grown in Shubak, Jordan.

Authors: Alghonmeen, Reham D., Dmour, Saif M., Saghir, Sultan A. M., Abushattal, Saqr, Alnaimat, Sulaiman, Al-zharani, Mohammed, Nasr, Fahd A., Althunibat, Osama Y.

Source: Open Veterinary Journal; 2024, Vol. 14 Issue 4, p990-1001, 12p

Subject Terms: METHICILLIN-resistant staphylococcus aureus, ETHYL acetate, ESCHERICHIA coli, KLEBSIELLA pneumoniae, COLORECTAL cancer, ARTEMISIA

Geographic Terms: JORDAN

Visnagin prevents isoproterenol‐induced myocardial injury by attenuating oxidative stress and inflammation and upregulating Nrf2 signaling in rats

Authors: Abukhalil, Mohammad H., Hussein, Omnia E., Aladaileh, Saleem H., Althunibat, Osama Y., Al‐Amarat, Wesam, Saghir, Sultan A., Alfwuaires, Manal A., Algefare, Abdulmohsen I., Alanazi, Khalid M., Al‐Swailmi, Farhan K., Kamel, Emadeldin M., Mahmoud, Ayman M.

Source: Journal of biochemical and molecular toxicology. 35(11)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134580594.0x000001&indx=1&recIds=ETOCvdc_100134580594.0x000001

Effect of Thymol and Carvacrol, the Major Components of Thymus capitatus on the Growth of Pseudomonas aeruginosa

Authors: Althunibat, Osama Y., Qaralleh, Haitham, Al-Dalin, Sati Yassin Ahmed, Abboud, Muayad, Khleifat, Khaled, Majali, Ibrahim S., Aldal in, Hammad K. H., Rayyan, Walid A., Jaafraa, Ahmad

Source: Journal of pure & applied microbiology. 10(1):367-374

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN605755470&indx=1&recIds=ETOCRN605755470

A review on the epigenetics modifications to nanomaterials in humans and animals: Novel epigenetic regulator.

Authors: Aldal'in, Hammad K., Radhi, Khadija S., Alazragi, Reem, Abdelnour, Sameh, Abukhalil, Mohammad H., Askar, Ahmed M., Khalifa, Norhan E., Noreldin, Ahmed E., Althunibat, Osama Y., Arif, Muhammad, Abd El-Hack, Mohamed E.

Source: Annals of Animal Science; Jul2023, Vol. 23 Issue 3, p615-628, 14p

Subject Terms: EPIGENETICS, NANOSTRUCTURED materials, GENE expression, EPIGENOMICS, DNA methylation, ANIMAL diseases, NANOBIOTECHNOLOGY

Hepatoprotective effect of taxifolin on cyclophosphamide-induced oxidative stress, inflammation, and apoptosis in mice: Involvement of Nrf2/HO-1 signaling.

Authors: Althunibat, Osama Y., Abukhalil, Mohammad H., Jghef, Muthana M., Alfwuaires, Manal A., Algefare, Abdulmohsen I., Alsuwayt, Bader, Alazragi, Reem, Abourehab, Mohammed A. S., Almuqati, Afaf F., Karimulla, Shaik, Aladaileh, Saleem H.

Source: Biomolecules & Biomedicine; 2023, Vol. 23 Issue 4, p649-660, 12p

Protective role of Punica granatum L. peel extract against oxidative damage in experimental diabetic rats

Authors: Althunibat, Osama Y., Al-Mustafa, Ahmed H., Tarawneh, Khaled, Khleifat, Khaled M., Ridzwan, B.H., Qaralleh, Haitham N.

Source: In Process Biochemistry 2010 45(4):581-585

A review on the epigenetics modifications to nanomaterials in humans and animals: Novel epigenetic regulator

Authors: Aldal’in, Hammad K., Radhi, Khadija S., Alazragi, Reem, Abdelnour, Sameh, Abukhalil, Mohammad H., Askar, Ahmed M., Khalifa, Norhan E., Noreldin, Ahmed E., Althunibat, Osama Y., Arif, Muhammad, Abd El-Hack, Mohamed E.

Source: Annals of Animal Science; July 2023, Vol. 23 Issue: 3 p615-628, 14p

Taxifolin Prevents Cisplatin Nephrotoxicity by Modulating Nrf2/HO-1 Pathway and Mitigating Oxidative Stress and Inflammation in Mice.

Authors: Alanezi, Abdulkareem A., Almuqati, Afaf F., Alfwuaires, Manal A., Alasmari, Fawaz, Namazi, Nader I., Althunibat, Osama Y., Mahmoud, Ayman M.

Source: Pharmaceuticals (14248247); Nov2022, Vol. 15 Issue 11, p1310, 14p

Subject Terms: NUCLEAR factor E2 related factor, CELL death, CISPLATIN, OXIDATIVE stress

Punicalagin Protects against the Development of Methotrexate-Induced Hepatotoxicity in Mice via Activating Nrf2 Signaling and Decreasing Oxidative Stress, Inflammation, and Cell Death.

Authors: Al-khawalde, Alayn' Al-marddyah A., Abukhalil, Mohammad H., Jghef, Muthana M., Alfwuaires, Manal A., Alaryani, Fatima S., Aladaileh, Saleem H., Algefare, Abdulmohsen I., Karimulla, Shaik, Alasmari, Fawaz, Aldal'in, Hammad Khalifeh, Alanezi, Abdulkareem A., Althunibat, Osama Y.

Source: International Journal of Molecular Sciences; Oct2022, Vol. 23 Issue 20, p12334-N.PAG, 18p

Subject Terms: CELL death, OXIDATIVE stress, NUCLEAR factor E2 related factor, HEPATOTOXICOLOGY, ASPARTATE aminotransferase, MICE, CATALASE, SUPEROXIDE dismutase

Upregulation of Nrf2/HO-1 Signaling and Attenuation of Oxidative Stress, Inflammation, and Cell Death Mediate the Protective Effect of Apigenin against Cyclophosphamide Hepatotoxicity.

Authors: Al-Amarat, Wesam, Abukhalil, Mohammad H., Alruhaimi, Reem S., Alqhtani, Haifa A., Aldawood, Nouf, Alfwuaires, Manal A., Althunibat, Osama Y., Aladaileh, Saleem H., Algefare, Abdulmohsen I., Alanezi, Abdulkareem A., AbouEl-ezz, Ali M., Ahmeda, Ahmad F., Mahmoud, Ayman M.

Source: Metabolites (2218-1989); Jul2022, Vol. 12 Issue 7, pN.PAG-N.PAG, 14p

Subject Terms: CELL death, OXIDATIVE stress, APIGENIN, HEPATOTOXICOLOGY, CYCLOPHOSPHAMIDE, REACTIVE oxygen species, ALKALINE phosphatase