NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism

Authors: Allouche, Jennifer, Rachmin, Inbal, Adhikari, Kaustubh, Pardo, Luba M., Lee, Ju Hee, McConnell, Alicia M., Kato, Shinichiro, Fan, Shaohua, Kawakami, Akinori, Suita, Yusuke, Wakamatsu, Kazumasa, Igras, Vivien, Zhang, Jianming, Navarro, Paula P., Lugo, Camila Makhlouta, Noonan, Haley R., Christie, Kathleen A., Itin, Kaspar, Mujahid, Nisma, Lo, Jennifer A., Won, Chong Hyun, Evans, Conor L., Weng, Qing Yu, Wang, Hequn, Osseiran, Sam, Lovas, Alyssa, Németh, István, Cozzio, Antonio, Navarini, Alexander A., Hsiao, Jennifer J., Nguyen, Nhu, Kemény, Lajos V., Iliopoulos, Othon, Berking, Carola, Ruzicka, Thomas, Gonzalez-José, Rolando, Bortolini, Maria-Cátira, Canizales-Quinteros, Samuel, Acuna-Alonso, Victor, Gallo, Carla, Poletti, Giovanni, Bedoya, Gabriel, Rothhammer, Francisco, Ito, Shosuke, Schiaffino, Maria Vittoria, Chao, Luke H., Kleinstiver, Benjamin P., Tishkoff, Sarah, Zon, Leonard I., Nijsten, Tamar, Ruiz-Linares, Andrés, Fisher, David E., Roider, Elisabeth

Source: In Cell 5 August 2021 184(16):4268-4283

Generation of heterozygous and homozygous NF1 lines from human-induced pluripotent stem cells using CRISPR/Cas9 to investigate bone defects associated with neurofibromatosis type 1.

Authors: Darle, Annabelle, Mahiet, Thibault, Aubin, Déborah, Doyen, Manon, El Kassar, Lina, Parfait, Béatrice, Lemaitre, Gilles, Baldeschi, Christine, Allouche, Jennifer, Holic, Nathalie

Source: Frontiers in Cell & Developmental Biology; 2024, p1-12, 12p

Subject Terms: PLURIPOTENT stem cells, CRISPRS, GENOME editing, MESENCHYMAL stem cells, NEUROFIBROMATOSIS 1, GENETIC variation, GENETIC disorders

In vitro modeling of hyperpigmentation associated to neurofibromatosis type 1 using melanocytes derived from human embryonic stem cells

Authors: Allouche, Jennifer, Bellon, Nathalia, Saidani, Manoubia, Stanchina-Chatrousse, Laure, Masson, Yolande, Patwardhan, Anand, Gilles-Marsens, Floriane, Delevoye, Cédric, Domingues, Sophie, Nissan, Xavier, Martinat, Cécile, Lemaitre, Gilles, Peschanski, Marc, Baldeschi, Christine

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Jul . 112(29), 9034-9039.

Access URL: https://www.jstor.org/stable/26466105

Generating Functional and Highly Proliferative Melanocytes Derived from Human Pluripotent Stem Cells: A Promising Tool for Biotherapeutic Approaches to Treat Skin Pigmentation Disorders.

Authors: Saidani, Manoubia, Darle, Annabelle, Jarrige, Margot, Polveche, Hélène, El Kassar, Lina, Julié, Séverine, Bessou-Touya, Sandrine, Holic, Nathalie, Lemaitre, Gilles, Martinat, Cécile, Baldeschi, Christine, Allouche, Jennifer

Source: International Journal of Molecular Sciences; Apr2023, Vol. 24 Issue 7, p6398, 20p

Subject Terms: HUMAN stem cells, PIGMENTATION disorders, MELANOCYTES, PLURIPOTENT stem cells, SKIN regeneration, HOMEOSTASIS, SKIN biopsy

A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin

Authors: Mujahid, Nisma, Liang, Yanke, Murakami, Ryo, Choi, Hwan Geun, Dobry, Allison S., Wang, Jinhua, Suita, Yusuke, Weng, Qing Yu, Allouche, Jennifer, Kemeny, Lajos V., Hermann, Andrea L., Roider, Elisabeth M., Gray, Nathanael S., Fisher, David E.

Source: In Cell Reports 13 June 2017 19(11):2177-2184

Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses.

Authors: Lo, Jennifer A., Kawakubo, Masayoshi, Juneja, Vikram R., Su, Mack Y., Erlich, Tal H., LaFleur, Martin W., Kemeny, Lajos V., Rashid, Mamunur, Malehmir, Mohsen, Rabi, S. Alireza, Raghavan, Rumya, Allouche, Jennifer, Kasumova, Gyulnara, Frederick, Dennie T., Pauken, Kristen E., Weng, Qing Yu, Pereira da Silva, Marcelo, Xu, Yu, van der Sande, Anita A. J., Silkworth, Whitney

Source: Science Translational Medicine; 2/17/2021, Vol. 13 Issue 581, p1-12, 12p

Subject Terms: IMMUNE checkpoint inhibitors, ANTIGENS, CELLULAR recognition, PROGRAMMED cell death 1 receptors, T cells, AUTOANTIGENS, CELL populations, SPREADING cortical depression

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