Immune determinants of CAR-T cell expansion in solid tumor patients receiving GD2 CAR-T cell therapy

Authors: Kaczanowska, Sabina, Murty, Tara, Alimadadi, Ahmad, Contreras, Cristina F., Duault, Caroline, Subrahmanyam, Priyanka B., Reynolds, Warren, Gutierrez, Norma A., Baskar, Reema, Wu, Catherine J., Michor, Franziska, Altreuter, Jennifer, Liu, Yang, Jhaveri, Aashna, Duong, Vandon, Anbunathan, Hima, Ong, Claire, Zhang, Hua, Moravec, Radim, Yu, Joyce, Biswas, Roshni, Van Nostrand, Stephen, Lindsay, James, Pichavant, Mina, Sotillo, Elena, Bernstein, Donna, Carbonell, Amanda, Derdak, Joanne, Klicka-Skeels, Jacquelyn, Segal, Julia E., Dombi, Eva, Harmon, Stephanie A., Turkbey, Baris, Sahaf, Bita, Bendall, Sean, Maecker, Holden, Highfill, Steven L., Stroncek, David, Glod, John, Merchant, Melinda, Hedrick, Catherine C., Mackall, Crystal L., Ramakrishna, Sneha, Kaplan, Rosandra N.

Source: In Cancer Cell 8 January 2024 42(1):35-51

Single‐cell immune profiling reveals long‐term changes in myeloid cells and identifies a novel subset of CD9+ monocytes associated with COVID‐19 hospitalization

Authors: Pandori, William J., Padgett, Lindsey E., Alimadadi, Ahmad, Gutierrez, Norma A., Araujo, Daniel J., Huh, Christine J., Olingy, Claire E., Dinh, Huy Q., Wu, Runpei, Vijayanand, Pandurangan, Chee, Serena J., Ottensmeier, Christian H., Hedrick, Catherine C.

Source: Journal of leukocyte biology. 112(5):1053-1063

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163236432.0x000001&indx=1&recIds=ETOCvdc_100163236432.0x000001

PD-1 and CD73 on naive CD4+T cells synergistically limit responses to self

Authors: Nettersheim, Felix Sebastian, Brunel, Simon, Sinkovits, Robert S., Armstrong, Sujit Silas, Roy, Payel, Billitti, Monica, Kobiyama, Kouji, Alimadadi, Ahmad, Bombin, Sergei, Lu, Lihui, Zoccheddu, Martina, Oliaeimotlagh, Mohammad, Benedict, Chris A., Sette, Alessandro, Ley, Klaus

Source: Nature Immunology; January 2025, Vol. 26 Issue: 1 p105-115, 11p

Olfr2-positive macrophages originate from monocytes proliferate in situ and present a pro-inflammatory foamy-like phenotype.

Authors: Suthahar, Sujit Silas Armstrong, Nettersheim, Felix Sebastian, Alimadadi, Ahmad, Wang, Erpei, Billitti, Monica, Resto-Trujillo, Natalya, Roy, Payel, Hedrick, Catherine C, Ley, Klaus, Orecchioni, Marco

Source: Cardiovascular Research; Sep2024, Vol. 120 Issue 13, p1577-1589, 13p

Subject Terms: MACROPHAGES, MYELOID cells, OLFACTORY receptors, WESTERN diet, ATHEROSCLEROTIC plaque

Single Cell High Dimensional Analysis of Human Peripheral Blood Mononuclear Cells Reveals Unique Intermediate Monocyte Subsets Associated with Sex Differences in Coronary Artery Disease.

Authors: Chatterjee, Nandini, Komaravolu, Ravi K., Durant, Christopher P., Wu, Runpei, McSkimming, Chantel, Drago, Fabrizio, Kumar, Sunil, Valentin-Guillama, Gabriel, Miller, Yury I., McNamara, Coleen A., Ley, Klaus, Taylor, Angela, Alimadadi, Ahmad, Hedrick, Catherine C.

Source: International Journal of Molecular Sciences; Mar2024, Vol. 25 Issue 5, p2894, 21p

Subject Terms: MONONUCLEAR leukocytes, CORONARY artery disease, DIMENSIONAL analysis, T cells, MONOCYTES, MYELOID cells, IMMUNOLOGIC memory

Geographic Terms: VIRGINIA

Machine Learning of Gut Microbiome Composition for Diagnostic Classification of Inflammatory Bowel Diseases

Authors: Manandhar, Ishan, Alimadadi, Ahmad, Aryal, Sachin, Munroe, Patricia, Joe, Bina, Cheng, Xi

Source: FASEB journal. 35

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125445469.0x000001&indx=1&recIds=ETOCvdc_100125445469.0x000001

Human CD79b⁺ neutrophils in the blood are associated with early-stage melanoma.

Authors: Meyer, Melissa A., Dinh, Huy Q., Alimadadi, Ahmad, Araujo, Daniel J., Chatterjee, Nandini, Gutierrez, Norma A., Zhu, Yanfang Peipei, Hunter, Emma L., Shu Liang, Seumois, Gregory, Kiosses, William B., Catz, Sergio D., Vijayanand, Pandurangan, Ottensmeier, Christian, Hedrick, Catherine C.

Source: Frontiers in Immunology; 2023, p1-14, 14p

Subject Terms: MELANOMA, NEUTROPHILS, HEAD & neck cancer, BONE marrow, BLOOD cells, B cells, RANDOM forest algorithms

Single cell transcriptomics reveals recent CD8T cell receptor signaling in patients with coronary artery disease.

Authors: Iqneibi, Shahad, Saigusa, Ryosuke, Khan, Amir, Oliaeimotlagh, Mohammad, Suthahar, Sujit Silas Armstrong, Kumar, Sunil, Alimadadi, Ahmad, Durant, Christopher P., Ghosheh, Yanal, McNamara, Coleen A., Hedrick, Catherine C., Ley, Klaus

Source: Frontiers in Immunology; 2023, p1-12, 12p

Subject Terms: CELL receptors, CORONARY artery disease, CELL communication, T cell receptors, T cells

Nonclassical monocytes potentiate anti-tumoral CD8+ T cell responses in the lungs.

Authors: Padgett, Lindsey E., Marcovecchio, Paola M., Olingy, Claire E., Araujo, Daniel J., Steel, Kathleen, Dinh, Huy Q., Alimadadi, Ahmad, Zhu, Yanfang Peipei, Meyer, Melissa A., Kiosses, William B., Thomas, Graham D., Hedrick, Catherine C.

Source: Frontiers in Immunology; 2023, p1-14, 14p

Subject Terms: T cells, MONOCYTES, CD8 antigen, IMMUNOLOGIC memory, CANCER cells

SEX AND SALT-RESPONSIVE CONJUGATION OF BILE ACIDS BY THE HOLOBIONT REGULATES HYPERTENSION

Authors: Chakraborty, Saroj Chakrabort, Lulla, Anju, Cheng, Xi, Mccarthy, Cameron G, Yeo, Ji-Youn, Alimadadi, Ahmad, Mandal, Juthika, Saha, Piu, Yeoh, Beng San, Louis, Evangelina F, Mell, Blair, Jia, Wei, Wenceslau, Camilla F, Vijay-Kumar, Matam, Meyer, Katie, Joe, Bina

Source: Journal of hypertension. 39(1):e263-e264

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185186660.0x000001&indx=1&recIds=ETOCvdc_100185186660.0x000001

Single‐cell immune profiling reveals long‐term changes in myeloid cells and identifies a novel subset of CD9⁺ monocytes associated with COVID‐19 hospitalization.

Authors: Pandori, William J., Padgett, Lindsey E., Alimadadi, Ahmad, Gutierrez, Norma A., Araujo, Daniel J., Huh, Christine J., Olingy, Claire E., Dinh, Huy Q., Wu, Runpei, Vijayanand, Pandurangan, Chee, Serena J., Ottensmeier, Christian H., Hedrick, Catherine C.

Source: Journal of Leukocyte Biology; Nov2022, Vol. 112 Issue 5, p1053-1063, 11p

Subject Terms: SARS-CoV-2, CORONAVIRUS diseases, MYELOID cells, MONOCYTES, COVID-19

Combined protein and transcript single-cell RNA sequencing in human peripheral blood mononuclear cells.

Authors: Vallejo, Jenifer, Saigusa, Ryosuke, Gulati, Rishab, Armstrong Suthahar, Sujit Silas, Suryawanshi, Vasantika, Alimadadi, Ahmad, Durant, Christopher P., Ghosheh, Yanal, Roy, Payel, Ehinger, Erik, Pattarabanjird, Tanyaporn, Hanna, David B., Landay, Alan L., Tracy, Russell P., Lazar, Jason M., Mack, Wendy J., Weber, Kathleen M., Adimora, Adaora A., Hodis, Howard N., Tien, Phyllis C.

Source: BMC Biology; 9/1/2022, Vol. 20 Issue 1, p1-19, 19p

Subject Terms: MONONUCLEAR leukocytes, MESSENGER RNA, RNA sequencing, KILLER cells, CRYOPRESERVATION of cells, CYTOMETRY

Geographic Terms: LOUVAIN (Belgium)

Sex Differences in Coronary Artery Disease and Diabetes Revealed by scRNA-Seq and CITE-Seq of Human CD4+ T Cells.

Authors: Saigusa, Ryosuke, Vallejo, Jenifer, Gulati, Rishab, Suthahar, Sujit Silas Armstrong, Suryawanshi, Vasantika, Alimadadi, Ahmad, Makings, Jeffrey, Durant, Christopher P., Freuchet, Antoine, Roy, Payel, Ghosheh, Yanal, Pandori, William, Pattarabanjird, Tanyaporn, Drago, Fabrizio, Taylor, Angela, McNamara, Coleen A., Shemesh, Avishai, Lanier, Lewis L., Hedrick, Catherine C., Ley, Klaus

Source: International Journal of Molecular Sciences; Sep2022, Vol. 23 Issue 17, p9875, 21p

Subject Terms: CORONARY artery disease, MONONUCLEAR leukocytes, CD4 antigen, RISK perception, PEOPLE with diabetes, GERM cells, SEX (Biology)

CD33 Expression on Peripheral Blood Monocytes Predicts Efficacy of Anti-PD-1 Immunotherapy Against Non-Small Cell Lung Cancer.

Authors: Olingy, Claire, Alimadadi, Ahmad, Araujo, Daniel J., Barry, David, Gutierrez, Norma A., Werbin, Max Hardy, Arriola, Edurne, Patel, Sandip Pravin, Ottensmeier, Christian H., Dinh, Huy Q., Hedrick, Catherine C.

Source: Frontiers in Immunology; 4/14/2022, Vol. 13, p1-15, 15p

Subject Terms: NON-small-cell lung carcinoma, MONONUCLEAR leukocytes, MONOCYTES, MYELOID cells, CELL death

Single‐cell immune profiling reveals long‐term changes in myeloid cells and identifies a novel subset of CD9+monocytes associated with COVID‐19 hospitalization

Authors: Pandori, William J., Padgett, Lindsey E., Alimadadi, Ahmad, Gutierrez, Norma A., Araujo, Daniel J., Huh, Christine J., Olingy, Claire E., Dinh, Huy Q., Wu, Runpei, Vijayanand, Pandurangan, Chee, Serena J., Ottensmeier, Christian H., Hedrick, Catherine C.

Source: Journal of Leukocyte Biology; November 2022, Vol. 112 Issue: 5 p1053-1063, 11p

Sex differences in salt‐responsive modulation of bile acids by microbiota regulates Hypertension

Authors: Chakraborty, Saroj, Lulla, Anju, Cheng, Xi, McCarthy, Cameron G., Yeo, Ji-Youn, Alimadadi, Ahmad, Mandal, Juthika, Saha, Piu, Yeoh, Beng San, Louis, Evangelina F, Mell, Blair, Jia, Wei, Wenceslau, Camilla F., Kumar, Matam Vijay, Meyer, Katie

Source: FASEB journal. 34(S1):1-1

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140413755.0x000001&indx=1&recIds=ETOCvdc_100140413755.0x000001

Gut microbiome-based supervised machine learning for clinical diagnosis of inflammatory bowel diseases.

Authors: Manandhar, Ishan¹ (AUTHOR), Alimadadi, Ahmad¹ (AUTHOR), Aryal, Sachin¹ (AUTHOR), Munroe, Patricia B.² (AUTHOR), Joe, Bina¹ (AUTHOR) bina.joe@utoledo.edu, Xi Cheng¹ (AUTHOR) Xi.Cheng@utoledo.edu

Source: American Journal of Physiology: Gastrointestinal & Liver Physiology. Mar2021, Vol. 320 Issue 3, pG328-G337. 10p. 3 Charts, 5 Graphs.

Machine Learning Strategy for Gut Microbiome-Based Diagnostic Screening of Cardiovascular Disease.

Authors: Aryal, Sachin, Alimadadi, Ahmad, Manandhar, Ishan, Joe, Bina, Cheng, Xi

Source: Hypertension (0194911X); Nov2020, Vol. 76 Issue 5, p1555-1562, 8p

Machine learning-based classification and diagnosis of clinical cardiomyopathies.

Authors: Alimadadi, Ahmad^1,2, Manandhar, Ishan^1,2, Aryal, Sachin^1,2, Munroe, Patricia B.³, Joe, Bina^1,2, Xi Cheng¹

Source: Physiological Genomics. Sep2020, Vol. 52 Issue 9, p391-400. 10p.

Subject Terms: *CARDIOMYOPATHIES, *HEART diseases, *CARDIAC hypertrophy, *DILATED cardiomyopathy, *MACHINE learning, *MEDICAL practice, *RADIAL distribution function

Artificial intelligence and machine learning to fight COVID-19.

Authors: Alimadadi, Ahmad^1,2 (AUTHOR), Aryal, Sachin^1,2 (AUTHOR), Manandhar, Ishan^1,2 (AUTHOR), Munroe, Patricia B.^1,2,3,4 (AUTHOR), Joe, Bina^1,2 (AUTHOR), Xi Cheng^1,2 (AUTHOR) Xi.Cheng@utoledo.edu

Source: Physiological Genomics. Apr2020, Vol. 52 Issue 4, p200-202. 3p. 1 Diagram.