Reduced exposure to vasopressors through permissive hypotension to reduce mortality in critically ill people aged 65 and over: the 65 RCT

Authors: Paul R Mouncey, Alvin Richards-Belle, Karen Thomas, David A Harrison, M Zia Sadique, Richard D Grieve, Julie Camsooksai, Robert Darnell, Anthony C Gordon, Doreen Henry, Nicholas Hudson, Alexina J Mason, Michelle Saull, Chris Whitman, J Duncan Young, François Lamontagne, Kathryn M Rowan, the 65 trial investigators

Source: Health Technology Assessment, Vol 25, Iss 14 (2021)

Subject Terms: vasopressors, mean arterial pressure, blood pressure, critical care, intensive care, clinical trial, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1366-5278; https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/7608f160200d4a5d990ce3ec840ec1a1

Levosimendan to prevent acute organ dysfunction in sepsis: the LeoPARDS RCT

Authors: Anthony C Gordon, Shalini Santhakumaran, Farah Al-Beidh, Robert ML Orme, Gavin D Perkins, Mervyn Singer, Daniel F McAuley, Alexina J Mason, Josie K Ward, Kieran P O’Dea, Timothy Felton, Mary Cross, Janis Best-Lane, Jonas Lexow, Ashley Campbell, Deborah Ashby

Source: Efficacy and Mechanism Evaluation, Vol 5, Iss 6 (2018)

Subject Terms: acute kidney injury, bilirubin, biomarkers, blood pressure, cardiac output, cardiovascular failure, catecholamines, intensive care unit, outcome assessment, randomised placebo controlled trial, renal replacement therapy, septic shock, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2050-4365; https://doaj.org/toc/2050-4373

Access URL: https://doaj.org/article/0fdb3781dce7473aa22a1e9ace439a37

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A framework for extending trial design to facilitate missing data sensitivity analyses

Authors: Alexina J. Mason, Richard D. Grieve, Alvin Richards-Belle, Paul R. Mouncey, David A. Harrison, James R. Carpenter

Source: BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-12 (2020)

Subject Terms: Bayesian analysis, Clinical trials, Expert elicitation, Missing data, Pattern-mixture models, Sensitivity analysis, Medicine (General), R5-920

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12874-020-00930-2; https://doaj.org/toc/1471-2288

Access URL: https://doaj.org/article/9619989e72c24fa7af6bb9a2acd64f77