Assessing bnAb potency in the context of HIV-1 envelope conformational plasticity.

Authors: Caio Foulkes, Nikolas Friedrich, Branislav Ivan, Emanuel Stiegeler, Carsten Magnus, Daniel Schmidt, Umut Karakus, Jacqueline Weber, Huldrych F Günthard, Chloé Pasin, Peter Rusert, Alexandra Trkola

Source: PLoS Pathogens, Vol 21, Iss 1, p e1012825 (2025)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/dd0d82584f014225b37d6d2cb1c3abd6

Low agreement and frequent invalid controls in two SARS-CoV-2 T-cell assays in people with compromised immune function.

Authors: Annette Audigé, Alain Amstutz, Macé M Schuurmans, Patrizia Amico, Dominique L Braun, Marcel P Stoeckle, Barbara Hasse, René Hage, Dominik Damm, Michael Tamm, Nicolas J Mueller, Huldrych F Günthard, Michael T Koller, Christof M Schönenberger, Alexandra Griessbach, Niklaus D Labhardt, Roger D Kouyos, Alexandra Trkola, Michael Huber, Katharina Kusejko, Heiner C Bucher, Irene A Abela, Matthias Briel, Frédérique Chammartin, Benjamin Speich, Swiss HIV Cohort Study, and the Swiss Transplant Cohort Study

Source: PLoS ONE, Vol 20, Iss 1, p e0317965 (2025)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cf332baac2ef4ecabefd3ce669c11759

ART-DEX: A novel strategy to monitor broadly neutralizing antibody activity during antiretroviral therapy of HIV-1

Authors: Magdalena Schwarzmüller, Alexandra Trkola

Source: STAR Protocols, Vol 5, Iss 3, Pp 103056- (2024)

Subject Terms: Cell Biology, Cell culture, High Throughput Screening, Immunology, Microbiology, Antibody, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166724002211; https://doaj.org/toc/2666-1667

Access URL: https://doaj.org/article/20c7187eb22842cba00cb82bd65d5b15

Decoupling HIV-1 antiretroviral drug inhibition from plasma antibody activity to evaluate broadly neutralizing antibody therapeutics and vaccines

Authors: Magdalena Schwarzmüller, Cristina Lozano, Merle Schanz, Irene A. Abela, Silvan Grosse-Holz, Selina Epp, Martina Curcio, Jule Greshake, Peter Rusert, Michael Huber, Roger D. Kouyos, Huldrych F. Günthard, Alexandra Trkola

Source: Cell Reports Medicine, Vol 5, Iss 9, Pp 101702- (2024)

Subject Terms: HIV-1, neutralizing antibody, antiretroviral therapy, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666379124004233; https://doaj.org/toc/2666-3791

Access URL: https://doaj.org/article/a726c3b8bb5347b0a26db15a5cdb413e

How much should we sequence? An analysis of the Swiss SARS-CoV-2 surveillance effort

Authors: Fanny Wegner, Blanca Cabrera-Gil, Araud Tanguy, Christiane Beckmann, Niko Beerenwinkel, Claire Bertelli, Matteo Carrara, Lorenzo Cerutti, Chaoran Chen, Samuel Cordey, Alexis Dumoulin, Louis du Plessis, Marc Friedli, Yannick Gerth, Gilbert Greub, Adrian Härri, Hans Hirsch, Cedric Howald, Michael Huber, Alexander Imhof, Laurent Kaiser, Verena Kufner, Stephen L. Leib, Karoline Leuzinger, Etleva Lleshi, Gladys Martinetti, Mirjam Mäusezahl, Milo Moraz, Richard Neher, Oliver Nolte, Alban Ramette, Maurice Redondo, Lorenz Risch, Lionel Rohner, Tim Roloff, Pascal Schläepfer, Katrin Schneider, Franziska Singer, Valeria Spina, Tanja Stadler, Erik Studer, Ivan Topolsky, Alexandra Trkola, Daniel Walther, Nadia Wohlwend, Cinzia Zehnder, Aitana Neves, Adrian Egli

Source: Microbiology Spectrum, Vol 12, Iss 5 (2024)

Subject Terms: SARS-CoV-2, surveillance studies, genomic surveillance, whole genome sequencing, modeling, molecular epidemiology, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/c4ccaa18016f452ba4419207aed44b4b

Exploring viral aetiology in upper respiratory tract infections: insights from metagenomic next-generation sequencing in Swiss outpatients before and during the SARS-CoV-2 pandemic

Authors: Verena Kufner, Andrea C. Frey, Sara H. Burkhard, Stefan Schmutz, Gabriela Ziltener, Maryam Zaheri, Caroline V. Wiedmer, Andreas Plate, Alexandra Trkola, Michael Huber, Nicolas J. Mueller

Source: Swiss Medical Weekly, Vol 154, Iss 4 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://smw.ch/index.php/smw/article/view/3797; https://doaj.org/toc/1424-3997

Access URL: https://doaj.org/article/7e495464ca974744b327ddaf778b99f2

Assessing immunogenicity barriers of the HIV-1 envelope trimer

Authors: Liridona Maliqi, Nikolas Friedrich, Matthias Glögl, Stefan Schmutz, Daniel Schmidt, Peter Rusert, Merle Schanz, Maryam Zaheri, Chloé Pasin, Cyrille Niklaus, Caio Foulkes, Thomas Reinberg, Birgit Dreier, Irene Abela, David Peterhoff, Alexandra Hauser, Roger D. Kouyos, Huldrych F. Günthard, Marit J. van Gils, Rogier W. Sanders, Ralf Wagner, Andreas Plückthun, Alexandra Trkola

Source: npj Vaccines, Vol 8, Iss 1, Pp 1-14 (2023)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2059-0105

Access URL: https://doaj.org/article/3c1b7ec8277b4efcb7d60e82c1710437

Cross-protective HCoV immunity reduces symptom development during SARS-CoV-2 infection

Authors: Irene A. Abela, Magdalena Schwarzmüller, Agne Ulyte, Thomas Radtke, Sarah R. Haile, Priska Ammann, Alessia Raineri, Sonja Rueegg, Selina Epp, Christoph Berger, Jürg Böni, Amapola Manrique, Annette Audigé, Michael Huber, Peter W. Schreiber, Thomas Scheier, Jan Fehr, Jacqueline Weber, Peter Rusert, Huldrych F. Günthard, Roger D. Kouyos, Milo A. Puhan, Susi Kriemler, Alexandra Trkola, Chloé Pasin

Source: mBio, Vol 15, Iss 2 (2024)

Subject Terms: SARS-CoV-2, pre-exisiting immunity, cross-immunity, respiratory infection, HCoV, children, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/872636c2b790494c92aab9ac0e622d10

Long-term course of neutralising antibodies against SARS-CoV-2 in vaccinated and unvaccinated staff and residents in a Swiss nursing home: a cohort study 2021–2022

Authors: Lisa Perrig, Irene A. Abela, Nicolas Banholzer, Annette Audigé, Selina Epp, Catrina Mugglin, Kathrin Zürcher, Matthias Egger, Alexandra Trkola, Lukas Fenner

Source: Swiss Medical Weekly, Vol 153, Iss 12 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://smw.ch/index.php/smw/article/view/3502; https://doaj.org/toc/1424-3997

Access URL: https://doaj.org/article/43c4abed8bfa45fdaaad1391800d5574

Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity

Authors: Irene A. Abela, Chloé Pasin, Magdalena Schwarzmüller, Selina Epp, Michèle E. Sickmann, Merle M. Schanz, Peter Rusert, Jacqueline Weber, Stefan Schmutz, Annette Audigé, Liridona Maliqi, Annika Hunziker, Maria C. Hesselman, Cyrille R. Niklaus, Jochen Gottschalk, Eméry Schindler, Alexander Wepf, Urs Karrer, Aline Wolfensberger, Silvana K. Rampini, Patrick M. Meyer Sauteur, Christoph Berger, Michael Huber, Jürg Böni, Dominique L. Braun, Maddalena Marconato, Markus G. Manz, Beat M. Frey, Huldrych F. Günthard, Roger D. Kouyos, Alexandra Trkola

Source: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/9ae1432b592c419493eac058f90406ee

Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization

Authors: Nikolas Friedrich, Emanuel Stiegeler, Matthias Glögl, Thomas Lemmin, Simon Hansen, Claus Kadelka, Yufan Wu, Patrick Ernst, Liridona Maliqi, Caio Foulkes, Mylène Morin, Mustafa Eroglu, Thomas Liechti, Branislav Ivan, Thomas Reinberg, Jonas V. Schaefer, Umut Karakus, Stephan Ursprung, Axel Mann, Peter Rusert, Roger D. Kouyos, John A. Robinson, Huldrych F. Günthard, Andreas Plückthun, Alexandra Trkola

Source: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ecac0450d3ce4cd7a9cab854f96059f2

A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®

Authors: Benjamin Speich, Frédérique Chammartin, Daniel Smith, Marcel P. Stoeckle, Patrizia Amico, Anna L. Eichenberger, Barbara Hasse, Macé M. Schuurmans, Thomas Müller, Michael Tamm, Michael Dickenmann, Irene A. Abela, Alexandra Trkola, Hans H. Hirsch, Oriol Manuel, Matthias Cavassini, Lars G. Hemkens, Matthias Briel, Nicolas J. Mueller, Andri Rauch, Huldrych F. Günthard, Michael T. Koller, Heiner C. Bucher, Katharina Kusejko, in collaboration with the study groups from the Swiss HIV Cohort Study and the Swiss Transplant Cohort Study

Source: Trials, Vol 22, Iss 1, Pp 1-16 (2021)

Subject Terms: SARS-CoV-2, Randomized controlled trial, HIV, Organ transplant, Platform trial, Vaccine, Protocol, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/2128b74ef7444eeeafbfd6921999843a

Postvaccination anti-S IgG levels predict anti-SARS-CoV-2 neutralising activity over 24 weeks in patients with RA

Authors: Johannes von Kempis, Andrea Rubbert-Roth, Burkhard Ludewig, Irene A Abela, Magdalena Schwarzmueller, Alexandra Trkola, Sabrina Pagano, Nicolas Vuilleumier, Kristin Schmiedeberg, Natalia Barbara Pikor, Selina Epp, Sarah Grabherr, Angelica Brooke Patterson, Madalina Nussberger

Source: RMD Open, Vol 8, Iss 2 (2022)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://rmdopen.bmj.com/content/8/2/e002575.full; https://doaj.org/toc/2056-5933

Access URL: https://doaj.org/article/49f5af80ace247819dba1ad5b207b03b

Do we cause false positives? An experimental series on droplet or airborne SARS-CoV-2 contamination of sampling tubes during swab collection in a test center

Authors: Thomas Scheier, Cyril Shah, Michael Huber, Hugo Sax, Barbara Hasse, Huldrych F. Günthard, Alexandra Trkola, Peter W. Schreiber

Source: Antimicrobial Resistance and Infection Control, Vol 10, Iss 1, Pp 1-4 (2021)

Subject Terms: SARS-CoV-2, COVID-19, False-positive test results, Contamination, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/2047-2994

Access URL: https://doaj.org/article/7b8286c0b2fe4fb0aa6ed631375455bb

Antibodies from convalescent plasma promote SARS-CoV-2 clearance in individuals with and without endogenous antibody response

Authors: Maddalena Marconato, Irene A. Abela, Anthony Hauser, Magdalena Schwarzmüller, Rheliana Katzensteiner, Dominique L. Braun, Selina Epp, Annette Audigé, Jacqueline Weber, Peter Rusert, Eméry Schindler, Chloé Pasin, Emily West, Jürg Böni, Verena Kufner, Michael Huber, Maryam Zaheri, Stefan Schmutz, Beat M. Frey, Roger D. Kouyos, Huldrych F. Günthard, Markus G. Manz, Alexandra Trkola

Source: The Journal of Clinical Investigation, Vol 132, Iss 12 (2022)

Subject Terms: COVID-19, Therapeutics, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/297d34da9c8446cd95b66a14cc84d8ad

Evolution of SARS-CoV-2 seroprevalence and clusters in school children from June 2020 to April 2021: prospective cohort study Ciao Corona

Authors: Agne Ulyte, Thomas Radtke, Irene A. Abela, Sarah R. Haile, Priska Ammann, Christoph Berger, Alexandra Trkola, Jan Fehr, Milo A. Puhan, Susi Kriemler

Source: Swiss Medical Weekly, Vol 151, Iss 4546 (2021)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://www.smw.ch/index.php/smw/article/view/3106; https://doaj.org/toc/1424-3997

Access URL: https://doaj.org/article/85649719850944c99bed2d67e106ffeb

The TransFLUas influenza transmission study in acute healthcare - recruitment rates and protocol adherence in healthcare workers and inpatients

Authors: Hila Schwarz, Jürg Böni, Roger D. Kouyos, Teja Turk, Edouard Battegay, Malcolm Kohler, Rouven Müller, Heidi Petry, Hugo Sax, Rainer Weber, Allison McGeer, Alexandra Trkola, Stefan P. Kuster

Source: BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-9 (2019)

Subject Terms: Influenza, Transmission, Asymptomatic infection, Surveillance, Healthcare-associated infection, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12879-019-4057-5; https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/cfa72d6c4947420fb00b3572490b5204

Variation in SARS-CoV-2 seroprevalence across districts, schools and classes: baseline measurements from a cohort of primary and secondary school children in Switzerland

Authors: Sarah R Haile, Milo Alan Puhan, Anja Frei, Agne Ulyte, Christoph Berger, Susi Kriemler, Thomas Radtke, Michael Huber, Merle Schanz, Magdalena Schwarzmueller, Alexandra Trkola, Jan Fehr, Irene Alma Abela, Jacob Blankenberger, Ruedi Jung, Celine Capelli

Source: BMJ Open, Vol 11, Iss 7 (2021)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/11/7/e047483.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/1700a19e521b4d53932e6812efaba54c

Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies

Authors: Christophe Caillat, Delphine Guilligay, Johana Torralba, Nikolas Friedrich, Jose L Nieva, Alexandra Trkola, Christophe J Chipot, François L Dehez, Winfried Weissenhorn

Source: eLife, Vol 10 (2021)

Subject Terms: HIV-1, gp41, membrane fusion, LN01, 4E10, 2H10, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/65005; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/c1f8eb01d322414cb7d10e348e2d38dc

SARS-CoV-2 variants reveal features critical for replication in primary human cells.

Authors: Marie O Pohl, Idoia Busnadiego, Verena Kufner, Irina Glas, Umut Karakus, Stefan Schmutz, Maryam Zaheri, Irene Abela, Alexandra Trkola, Michael Huber, Silke Stertz, Benjamin G Hale

Source: PLoS Biology, Vol 19, Iss 3, p e3001006 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/942eb63eba2e43ccbc2ad9759b98db2c