T-bet+ B cells are activated by and control endogenous retroviruses through TLR-dependent mechanisms

Authors: Eileen Rauch, Timm Amendt, Aleksandra Lopez Krol, Fabian B. Lang, Vincent Linse, Michelle Hohmann, Ann-Christin Keim, Susanne Kreutzer, Kevin Kawengian, Malte Buchholz, Philipp Duschner, Saskia Grauer, Barbara Schnierle, Andreas Ruhl, Ingo Burtscher, Sonja Dehnert, Chege Kuria, Alexandra Kupke, Stephanie Paul, Thomas Liehr, Marcus Lechner, Markus Schnare, Andreas Kaufmann, Magdalena Huber, Thomas H. Winkler, Stefan Bauer, Philipp Yu

Source: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/614f814272ae48b086e1c7fdf428b850

Rapid Development of Modified Vaccinia Virus Ankara (MVA)-Based Vaccine Candidates Against Marburg Virus Suitable for Clinical Use in Humans

Authors: Alina Tscherne, Georgia Kalodimou, Alexandra Kupke, Cornelius Rohde, Astrid Freudenstein, Sylvia Jany, Satendra Kumar, Gerd Sutter, Verena Krähling, Stephan Becker, Asisa Volz

Source: Vaccines, Vol 12, Iss 12, p 1316 (2024)

Subject Terms: Modified Vaccinia virus Ankara (MVA), viral vector vaccine, emerging viruses, rapid vaccine development, Marburg virus, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/12/1316; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/335b9ecf356444e18bbf4b531bcb86ea

Increased neutralization and IgG epitope identification after MVA-MERS-S booster vaccination against Middle East respiratory syndrome

Authors: Anahita Fathi, Christine Dahlke, Verena Krähling, Alexandra Kupke, Nisreen M. A. Okba, Matthijs P. Raadsen, Jasmin Heidepriem, Marcel A. Müller, Grigori Paris, Susan Lassen, Michael Klüver, Asisa Volz, Till Koch, My L. Ly, Monika Friedrich, Robert Fux, Alina Tscherne, Georgia Kalodimou, Stefan Schmiedel, Victor M. Corman, Thomas Hesterkamp, Christian Drosten, Felix F. Loeffler, Bart L. Haagmans, Gerd Sutter, Stephan Becker, Marylyn M. Addo

Source: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/9c0741a645df4990aa04ffff02338df4

Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity

Authors: Christian Meyer zu Natrup, Alina Tscherne, Christine Dahlke, Malgorzata Ciurkiewicz, Dai-Lun Shin, Anahita Fathi, Cornelius Rohde, Georgia Kalodimou, Sandro Halwe, Leonard Limpinsel, Jan H. Schwarz, Martha Klug, Meral Esen, Nicole Schneiderhan-Marra, Alex Dulovic, Alexandra Kupke, Katrin Brosinski, Sabrina Clever, Lisa-Marie Schünemann, Georg Beythien, Federico Armando, Leonie Mayer, Marie L. Weskamm, Sylvia Jany, Astrid Freudenstein, Tamara Tuchel, Wolfgang Baumgärtner, Peter Kremsner, Rolf Fendel, Marylyn M. Addo, Stephan Becker, Gerd Sutter, Asisa Volz

Source: The Journal of Clinical Investigation, Vol 132, Iss 24 (2022)

Subject Terms: Infectious disease, Vaccines, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/c3dacfdcee5044c4a6d220158af4b33c

Short- and Long-Interval Prime-Boost Vaccination with the Candidate Vaccines MVA-SARS-2-ST and MVA-SARS-2-S Induces Comparable Humoral and Cell-Mediated Immunity in Mice

Authors: Georgia Kalodimou, Sylvia Jany, Astrid Freudenstein, Jan Hendrik Schwarz, Leonard Limpinsel, Cornelius Rohde, Alexandra Kupke, Stephan Becker, Asisa Volz, Alina Tscherne, Gerd Sutter

Source: Viruses, Vol 15, Iss 5, p 1180 (2023)

Subject Terms: Modified Vaccinia virus Ankara, SARS-CoV-2, preclinical testing, vaccinia virus, vector vaccine, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/15/5/1180; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/1273b01d73fc4963ac4a077943276725

Osteogenesis imperfecta in a male holstein calf associated with a possible oligogenic origin

Authors: Xuying Zhang, Marc Hirschfeld, Julia Beck, Alexandra Kupke, Kernt Köhler, Ekkehard Schütz, Bertram Brenig

Source: Veterinary Quarterly, Vol 40, Iss 1, Pp 58-67 (2020)

Subject Terms: bovine, cattle, cow, osteodysplasia, osteodystrophy, osteogenesis imperfecta, brittle bone disease, congenital bone disorder, embryo transfer, malformation, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/0165-2176; https://doaj.org/toc/1875-5941

Access URL: https://doaj.org/article/88dc0545da9246c083ff8a608fe869bd

Protective CD8+ T Cell Response Induced by Modified Vaccinia Virus Ankara Delivering Ebola Virus Nucleoprotein

Authors: Alexandra Kupke, Asisa Volz, Erik Dietzel, Astrid Freudenstein, Jörg Schmidt, Hosam Shams-Eldin, Sylvia Jany, Lucie Sauerhering, Verena Krähling, Michelle Gellhorn Serra, Christiane Herden, Markus Eickmann, Stephan Becker, Gerd Sutter

Source: Vaccines, Vol 10, Iss 4, p 533 (2022)

Subject Terms: Ebola virus, Modified Vaccinia virus Ankara, vaccine, correlates of protection, nucleoprotein, glycoprotein, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/10/4/533; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/c197fefc32064d6e8959d5b89150555f

Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection

Authors: Sandro Halwe, Alexandra Kupke, Kanika Vanshylla, Falk Liberta, Henning Gruell, Matthias Zehner, Cornelius Rohde, Verena Krähling, Michelle Gellhorn Serra, Christoph Kreer, Michael Klüver, Lucie Sauerhering, Jörg Schmidt, Zheng Cai, Fei Han, David Young, Guangwei Yang, Marek Widera, Manuel Koch, Anke Werner, Lennart Kämper, Nico Becker, Michael S. Marlow, Markus Eickmann, Sandra Ciesek, Felix Schiele, Florian Klein, Stephan Becker

Source: Viruses, Vol 13, Iss 8, p 1498 (2021)

Subject Terms: SARS-CoV-2, monoclonal antibody, neutralizing antibody, virus, animal experiments, mice, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/13/8/1498; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/a952a8244dfc4b74bafbb2519784edf5

Spectrum of pathogen- and model-specific histopathologies in mouse models of acute pneumonia.

Authors: Kristina Dietert, Birgitt Gutbier, Sandra M Wienhold, Katrin Reppe, Xiaohui Jiang, Ling Yao, Catherine Chaput, Jan Naujoks, Markus Brack, Alexandra Kupke, Christin Peteranderl, Stephan Becker, Carolin von Lachner, Nelli Baal, Hortense Slevogt, Andreas C Hocke, Martin Witzenrath, Bastian Opitz, Susanne Herold, Holger Hackstein, Leif E Sander, Norbert Suttorp, Achim D Gruber

Source: PLoS ONE, Vol 12, Iss 11, p e0188251 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5695780?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e118d1a225d845ef9ec169aa82829540

Intranasal location and immunohistochemical characterization of the equine olfactory epithelium

Authors: Alexandra Kupke, Sabine Wenisch, Klaus Failing, Christiane Herden

Source: Frontiers in Neuroanatomy, Vol 10 (2016)

Subject Terms: Immunohistochemistry, horse, statistical analysis, subtypes, olfactory epithelium, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Human anatomy, QM1-695

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fnana.2016.00097/full; https://doaj.org/toc/1662-5129

Access URL: https://doaj.org/article/fb20604737504515bc0df7163400db89