A Common Cell of Origin for Inflammatory Myofibroblastic Tumor and Lung Adenocarcinoma with ALK rearrangement

Authors: Nesteryuk, Vasyl, Hamdani, Omar, Gong, Raymond, Almog, Nava, Alexander, Brian M., Soosman, Steffan, Yoneda, Ken, Ali, Siraj M., Borowsky, Alexander D., Riess, Jonathan W.

Source: Clinical lung cancer. 23(8):e550-e555

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HPV51-associated Leiomyosarcoma

Authors: Williams, Erik A., Montesion, Meagan, Lincoln, Vadim, Tse, Julie Y., Hiemenz, Matthew C., Mata, Douglas A., Shah, Bhamini B., Shoroye, Adebowale, Alexander, Brian M., Werth, Adrienne J., Foley-Peres, Kathleen, Milante, Riza R., Ross, Jeffrey S., Ramkissoon, Shakti H., Williams, Kevin Jon, Adhikari, Laura J., Zuna, Rosemary E., LeBoit, Philip E., Lin, Douglas I., Elvin, Julia A.

Source: American journal of surgical pathology. 46(6):729-741

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155501333.0x000001&indx=1&recIds=ETOCvdc_100155501333.0x000001

Genomic profiling of solid tumors harboring BRD4-NUT and response to immune checkpoint inhibitors

Authors: Riess, Jonathan W., Rahman, Shaila, Kian, Waleed, Edgerly, Claire, Heilmann, Andreas M., Madison, Russell, Ramkissoon, Shakti H., Klaitman, Shai Shlomi, Chung, Jon H., Trabucco, Sally E., Jin, Dexter X., Alexander, Brian M., Klempner, Samuel J., Albacker, Lee A., Frampton, Garrett M., Roisman, Laila C., Miller, Vincent A., Ross, Jeffrey S., Schrock, Alexa B., Gregg, Jeffrey P., Peled, Nir, Sokol, Ethan S., Ali, Siraj M.

Source: In Translational Oncology October 2021 14(10)

Leveraging external data in the design and analysis of clinical trials in neuro-oncology

Authors: Rahman, Rifaquat ^*, Ventz, Steffen, McDunn, Jon, Louv, Bill, Reyes-Rivera, Irmarie, Polley, Mei-Yin C, Merchant, Fahar, Abrey, Lauren E, Allen, Joshua E, Aguilar, Laura K, Aguilar-Cordova, Estuardo, Arons, David, Tanner, Kirk, Bagley, Stephen, Khasraw, Mustafa, Cloughesy, Timothy, Wen, Patrick Y, Alexander, Brian M ^*, Trippa, Lorenzo ^*

Source: In The Lancet Oncology October 2021 22(10):e456-e465

CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features

Authors: Williams, Erik A., Montesion, Meagan, Alexander, Brian M., Ramkissoon, Shakti H., Elvin, Julia A., Ross, Jeffrey S., Williams, Kevin Jon, Glomski, Krzysztof, Bledsoe, Jacob R., Tse, Julie Y., Mochel, Mark C.

Source: In Modern Pathology February 2021 34(2):358-370

Real-world association of HER2/ERBB2 concordance with trastuzumab clinical benefit in advanced esophagogastric cancer

Authors: Stein, Stacey M, Snider, Jeremy, Ali, Siraj M, Miksad, Rebecca A, Alexander, Brian M, Castellanos, Emily, Schrock, Alexa B, Madison, Russell, Swaminathan, Akshay, Venstrom, Jeffrey M, McCusker, Margaret

Source: Future oncology. 17(31):4101-4114

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A molecularly integrated grade for meningioma

Authors: Driver, Joseph, Hoffman, Samantha E, Tavakol, Sherwin, Woodward, Eleanor, Maury, Eduardo A, Bhave, Varun, Greenwald, Noah F, Nassiri, Farshad, Aldape, Kenneth, Zadeh, Gelareh, Choudhury, Abrar, Vasudevan, Harish N, Magill, Stephen T, Raleigh, David R, Abedalthagafi, Malak, Aizer, Ayal A, Alexander, Brian M, Ligon, Keith L, Reardon, David A, Wen, Patrick Y, Al-Mefty, Ossama, Ligon, Azra H, Dubuc, Adrian M, Beroukhim, Rameen, Claus, Elizabeth B, Dunn, Ian F, Santagata, Sandro, Linda Bi, Wenya

Source: Neuro-oncology. 24(5):796-808

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100152562344.0x000001&indx=1&recIds=ETOCvdc_100152562344.0x000001

The use of external control data for predictions and futility interim analyses in clinical trials

Authors: Ventz, Steffen, Comment, Leah, Louv, Bill, Rahman, Rifaquat, Wen, Patrick Y, Alexander, Brian M, Trippa, Lorenzo

Source: Neuro-oncology. 24(2):247-256

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139940754.0x000001&indx=1&recIds=ETOCvdc_100139940754.0x000001

CYLD-mutant cylindroma-like basaloid carcinoma of the anus: a genetically and morphologically distinct class of HPV-related anal carcinoma

Authors: Williams, Erik A., Montesion, Meagan, Sharaf, Radwa, Corines, James, Patel, Parth J., Gillespie, Brendan J., Pavlick, Dean C., Sokol, Ethan S., Alexander, Brian M., Williams, Kevin Jon, Elvin, Julia A., Ross, Jeffrey S., Ramkissoon, Shakti H., Hemmerich, Amanda C., Tse, Julie Y., Mochel, Mark C.

Source: In Modern Pathology December 2020 33(12):2614-2625

Pan-sarcoma genomic analysis of KMT2A rearrangements reveals distinct subtypes defined by YAP1–KMT2A–YAP1 and VIM–KMT2A fusions

Authors: Massoth, Lucas R., Hung, Yin P., Nardi, Valentina, Nielsen, G. Petur, Hasserjian, Robert P., Louissaint, Abner, Jr., Fisch, Adam S., Deshpande, Vikram, Zukerberg, Lawrence R., Lennerz, Jochen K., Selig, Martin, Glomski, Krzysztof, Patel, Parth J., Williams, Kevin Jon, Sokol, Ethan S., Alexander, Brian M., Vergilio, Jo-Anne, Ross, Jeffrey S., Pavlick, Dean C., Chebib, Ivan, Williams, Erik A.

Source: In Modern Pathology November 2020 33(11):2307-2317

Retrospective analysis of real-world data to determine clinical outcomes of patients with advanced non-small cell lung cancer following cell-free circulating tumor DNA genomic profiling

Authors: Madison, Russell ^*, Schrock, Alexa B., Castellanos, Emily, Gregg, Jeffrey P., Snider, Jeremy, Ali, Siraj M., Miller, Vincent A., Singal, Gaurav, Alexander, Brian M., Venstrom, Jeffrey M., Chung, Jon H.

Source: In Lung Cancer October 2020 148:69-78

Melanomas with activating RAF1 fusions: clinical, histopathologic, and molecular profiles

Authors: Williams, Erik A., Shah, Nikunj, Montesion, Meagan, Sharaf, Radwa, Pavlick, Dean C., Sokol, Ethan S., Alexander, Brian M., Venstrom, Jeff M., Elvin, Julia A., Ross, Jeffrey S., Tse, Julie Y., Mochel, Mark C.

Source: In Modern Pathology August 2020 33(8):1466-1474

Comprehensive Assessment of Immuno-oncology Biomarkers in Adenocarcinoma, Urothelial Carcinoma, and Squamous-cell Carcinoma of the Bladder

Authors: Necchi, Andrea ^⁎, Madison, Russell, Raggi, Daniele, Jacob, Joseph M., Bratslavsky, Gennady, Shapiro, Oleg, Elvin, Julia A., Vergilio, Jo-Anne, Killian, Jonathan K., Ngo, Nhu, Ramkissoon, Shakti, Severson, Eric, Hemmerich, Amanda C., Huang, Richard, Ali, Siraj M., Chung, Jon H., Reddy, Prasanth, Miller, Vincent A., Schrock, Alexa B., Gay, Laurie M., Alexander, Brian M., Grivas, Petros, Ross, Jeffrey S.

Source: In European Urology April 2020 77(4):548-556

Atypical Histopathological Features and the Risk of Treatment Failure in Nonmalignant Meningiomas: A Multi-Institutional Analysis

Authors: Lamba, Nayan, Hwang, William L., Kim, Daniel W., Niemierko, Andrzej, Marciscano, Ariel E., Mehan, William A., Jr., Benayoun, Marc D., Curry, William T., Barker, Fred G., II, Martuza, Robert L., Dunn, Ian F., Claus, Elizabeth, Bi, Wenya Linda, Aizer, Ayal A., Alexander, Brian M., Oh, Kevin S., Loeffler, Jay S., Shih, Helen A.

Source: In World Neurosurgery January 2020 133:e804-e812

New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures

Authors: Boxer, Adam L., Gold, Michael, Feldman, Howard, Boeve, Bradley F., Dickinson, Susan L.-J., Fillit, Howard, Ho, Carole, Paul, Robert, Pearlman, Rodney, Sutherland, Margaret, Verma, Ajay, Arneric, Stephen P., Alexander, Brian M., Dickerson, Bradford C., Dorsey, Earl Ray, Grossman, Murray, Huey, Edward D., Irizarry, Michael C., Marks, William J., Masellis, Mario, McFarland, Frances, Niehoff, Debra, Onyike, Chiadi U., Paganoni, Sabrina, Panzara, Michael A., Rockwood, Kenneth, Rohrer, Jonathan D., Rosen, Howard, Schuck, Robert N., Soares, Holly D., Tatton, Nadine

Source: Alzheimer's & dementia. 16(1):131-143

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111019038.0x000001&indx=1&recIds=ETOCvdc_100111019038.0x000001

Urothelial cancer harbours EGFR and HER2 amplifications and exon 20 insertions

Authors: Madison, Russell W., Gupta, Sumati V., Elamin, Yasir Y., Lin, Douglas I., Pal, Sumanta K., Necchi, Andrea, Miller, Vincent A., Ross, Jeffrey S., Chung, Jon H., Alexander, Brian M., Schrock, Alexa B., Heymach, John V., Reddy, Prasanth, Ali, Siraj M.

Source: BJU international. 125(5):739-746

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107062886.0x000001&indx=1&recIds=ETOCvdc_100107062886.0x000001

Evidence‐Based Development and Clinical Use of Precision Oncology Therapeutics

Authors: Comment, Leah A., Ward, Ashley F., Schrock, Alexa B., Fabrizio, David, Venstrom, Jeffrey M., Hegde, Priti S., Alexander, Brian M.

Source: Clinical pharmacology & therapeutics. 108(3):440-443

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108113584.0x000001&indx=1&recIds=ETOCvdc_100108113584.0x000001

Prediction of Outcomes with a Computational Biology Model in Newly Diagnosed Glioblastoma Patients Treated with Radiation Therapy and Temozolomide

Authors: Rahman, Rifaquat, Trippa, Lorenzo, Alden, Stephanie, Fell, Geoffrey, Abbasi, Taher, Mundkur, Yatin, Singh, Neeraj K., Talawdekar, Anay, Husain, Zakir, Vali, Shireen, Ligon, Keith L., Wen, Patrick Y., Alexander, Brian M.

Source: International journal of radiation oncology, biology, physics. 108(3):716-724

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164527661.0x000001&indx=1&recIds=ETOCvdc_100164527661.0x000001

Neurosurgical Resection and Stereotactic Radiation Versus Stereotactic Radiation Alone in Patients with a Single or Solitary Brain Metastasis

Authors: Lamba, Nayan, Cagney, Daniel N., Brigell, Rachel H., Martin, Allison M., Besse, Luke A., Catalano, Paul J., Phillips, John G., Pashtan, Itai M., Bi, Wenya Linda, Claus, Elizabeth B., Golby, Alexandra J., Dunn, Ian F., Smith, Timothy R., Tanguturi, Shyam K., Haas-Kogan, Daphne A., Alexander, Brian M., Aizer, Ayal A.

Source: In World Neurosurgery February 2019 122:e1557-e1561

New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures

Authors: Boxer, Adam L., Gold, Michael, Feldman, Howard, Boeve, Bradley F., Dickinson, Susan L.-J., Fillit, Howard, Ho, Carole, Paul, Robert, Pearlman, Rodney, Sutherland, Margaret, Verma, Ajay, Arneric, Stephen P., Alexander, Brian M., Dickerson, Bradford C., Dorsey, Earl Ray, Grossman, Murray, Huey, Edward D., Irizarry, Michael C., Marks, William J., Masellis, Mario, McFarland, Frances, Niehoff, Debra, Onyike, Chiadi U., Paganoni, Sabrina, Panzara, Michael A., Rockwood, Kenneth, Rohrer, Jonathan D., Rosen, Howard, Schuck, Robert N., Soares, Holly D., Tatton, Nadine

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association